DNA-directed RNA polymerase I subunit RPA1 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	N-(2-(Dimethylamino)ethyl)-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide	IC50	50.0 [1]
	N-(2-(Dimethylamino)ethyl)-11-oxo-11H-pyrido(2,1-b)quinazoline-6-carboxamide	IC50	2170.0 [1]
	N-(2-Morpholin-4-ylethyl)-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide	IC50	1250.0 [1]
	N-[2-(1H-Indol-3-yl)ethyl]-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide	IC50	31700.0 [1]
	N-[2-(Dimethylamino)ethyl]-N-ethyl-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide	IC50	100000.0 [1]
	N-(2-Imidazol-1-ylethyl)-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide	IC50	980.0 [1]
	12-Oxo-N-(2-pyridin-3-ylethyl)-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide	IC50	11800.0 [1]
	12-Oxo-N-(2-pyridin-2-ylethyl)-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide	IC50	15840.0 [1]
	12-Oxo-N-[2-(2-oxoimidazolidin-1-yl)ethyl]-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide	IC50	13100.0 [1]
	N-(2-Methylsulfonylethyl)-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide	IC50	5210.0 [1]
	N-[4-(Dimethylamino)butyl]-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide	IC50	660.0 [1]
	N-[3-(Dimethylamino)propyl]-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide	IC50	430.0 [1]
	N-[2-(1-Methylpyrrolidin-2-yl)ethyl]-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide	IC50	2010.0 [1]
	N-[3-(Dimethylamino)propyl]-N-methyl-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide	IC50	33850.0 [1]
	N-(Azetidin-3-yl)-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide	IC50	210.0 [1]
	N-(1-Methylpiperidin-4-yl)-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide	IC50	180.0 [1]
	Tert-butyl 3-[(12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carbonyl)amino]azetidine-1-carboxylate	IC50	35400.0 [1]
	4-(4-Propan-2-ylpiperazine-1-carbonyl)-12H-benzo[g]pyrido[2,1-b]quinazolin-12-one	IC50	100000.0 [1]
	N-Methyl-N-(1-methylpyrrolidin-3-yl)-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide	IC50	41990.0 [1]
	4-[(3S)-3-(Dimethylamino)pyrrolidine-1-carbonyl]-12H-benzo[g]pyrido[2,1-b]quinazolin-12-one	IC50	100000.0 [1]
	4-[3-(Diethylamino)pyrrolidine-1-carbonyl]-12H-benzo[g]pyrido[2,1-b]quinazolin-12-one	IC50	31800.0 [1]
	12-Oxo-N-(2-piperidin-1-ylethyl)-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide	IC50	180.0 [1]
	12-Oxo-N-(2-pyrrolidin-1-ylethyl)-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide	IC50	90.0 [1]
	N-[2-(Diethylamino)ethyl]-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide	IC50	140.0 [1]
	N-[1-(Dimethylamino)propan-2-yl]-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide	IC50	110.0 [1]
	CID 90644360	IC50	40.0 [1]
	N-[2-[Di(propan-2-yl)amino]ethyl]-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide	IC50	3040.0 [1]
	N-[2-(4-Methylpiperazin-1-yl)ethyl]-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide	IC50	1090.0 [1]
	N-[2-[2-Methoxyethyl(methyl)amino]ethyl]-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide	IC50	730.0 [1]
	N-[2-(Diethylamino)ethyl]-11-oxopyrido[2,1-b]quinazoline-6-carboxamide	IC50	1350.0 [1]
	2-(Dimethylamino)ethyl 12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxylate	IC50	50900.0 [1]
	N-[2-(Dimethylamino)ethyl]-N-methyl-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide	IC50	22100.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 32 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ DNA-directed RNA polymerase I subunit RPA1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/dna-directed-rna-polymerase-i-subunit-rpa1-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 21). Quest Database™ DNA-directed RNA polymerase I subunit RPA1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/dna-directed-rna-polymerase-i-subunit-rpa1-inhibitors-ic50-ki.
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