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Deoxyribonuclease-1 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
Gentian violet cationIC50350.0 [1]
5,6-Dihydroxy-2-phenylpyrimidine-4-carboxylic acidIC50100000.0 [1]
5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxylic acidIC50100000.0 [1]
N-(4-Fluorobenzyl)-5,6-dihydroxy-2-thien-2-ylpyrimidine-4-carboxamideIC50100000.0 [1]
3-Hydroxyquinazoline-2,4(1H,3H)-dioneIC50100000.0 [1]
4-(4,6-Dichloro-1,3,5-triazin-2-ylamino)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acidIC50300000.0 [1]
5-Hydroxy-1-methyl-6-oxo-2-(2-thienyl)pyrimidine-4-carboxylic acidIC50100000.0 [1]
3-Hydroxy-1H-thieno[2,3-d]pyrimidine-2,4-dioneIC50100000.0 [1]
5,6-Dihydroxy-2-(2-thienyl)pyrimidine-4-carboxamideIC50100000.0 [1]
5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxylic acid methyl esterIC50100000.0 [1]
2(1H)-Pyridinone, 5-(4-fluorophenyl)-3-hydroxy-IC50100000.0 [1]
3-Hydroxy-7-phenyl-1H-thieno[3,2-d]pyrimidine-2,4-dioneIC50100000.0 [1]
3-Hydroxy-7-(4-methylphenyl)furo[3,2-d]pyrimidine-2,4(1H,3H)-dioneIC50100000.0 [1]
1-Benzyl-3-hydroxythieno[2,3-d]pyrimidine-2,4(1H,3H)-dioneIC50100000.0 [1]
2-Anilino-N-[2-(3,4-dihydroxyphenyl)ethyl]acetamideIC50100000.0 [1]
2-Anilino-N-[(3,4-dihydroxyphenyl)methyl]acetamideIC50100000.0 [1]
2-Anilino-N-(3,4-dihydroxyphenyl)acetamideIC50100000.0 [1]
N-[(3,4-Dihydroxyphenyl)methyl]-3-phenylpropanamideIC50100000.0 [1]
N-[(3,4-Dihydroxyphenyl)methyl]-2-phenoxyacetamideIC50100000.0 [1]
N-[(3,4-Dihydroxyphenyl)methyl]-2-phenylacetamideIC50100000.0 [1]
2-(4-Chlorophenyl)-N-[(3,4-dihydroxyphenyl)methyl]acetamideIC50100000.0 [1]
2-(2-Chlorophenyl)-N-[(3,4-dihydroxyphenyl)methyl]acetamideIC50100000.0 [1]
2-(2,4-Dichlorophenyl)-N-[(3,4-dihydroxyphenyl)methyl]acetamideIC50100000.0 [1]
N-[(3,4-Dihydroxyphenyl)methyl]cyclopentanecarboxamideIC50100000.0 [1]
2-Cyclohexyl-N-[(3,4-dihydroxyphenyl)methyl]acetamideIC50100000.0 [1]
N-[(3,4-Dihydroxyphenyl)methyl]-2-(4-morpholin-4-ylphenyl)acetamideIC50100000.0 [1]
2-(4-Acetylpiperazin-1-yl)-N-[(3,4-dihydroxyphenyl)methyl]acetamideIC50100000.0 [1]
N-[(3,4-Dihydroxyphenyl)methyl]-1-[(4-fluorophenyl)methyl]piperidine-4-carboxamideIC50100000.0 [1]
2-(2,4-Dichlorophenyl)-1-(6,7-dihydroxy-3,4-dihydro-1H-isoquinolin-2-yl)ethanoneIC50100000.0 [1]
2-(2,4-Dichlorophenyl)-N-[(3,4-dihydroxyphenyl)methyl]-N-methylacetamideIC50100000.0 [1]
N-[(2-Chloro-3,4-dihydroxyphenyl)methyl]-2-(2,4-dichlorophenyl)acetamideIC50100000.0 [1]
2-(2,4-Dichlorophenyl)-N-[(2-fluoro-4,5-dihydroxyphenyl)methyl]acetamideIC50100000.0 [1]
1-(2,4-Dichlorophenyl)-N-[(3,4-dihydroxyphenyl)methyl]methanesulfonamideIC50100000.0 [1]
N-[(2,4-Dichlorophenyl)methyl]-2-(3,4-dihydroxyphenyl)acetamideIC50100000.0 [1]
1-(4-Chlorophenyl)-3-[(3,4-dihydroxyphenyl)methyl]ureaIC50100000.0 [1]
1-[(4-Chlorophenyl)methyl]-3-[(3,4-dihydroxyphenyl)methyl]imidazolidin-2-oneIC50100000.0 [1]
4-[[3-(4-Chlorophenyl)-1,2,4-oxadiazol-5-yl]methyl]benzene-1,2-diolIC50100000.0 [1]
3-Hydroxy-5-(3-pyrazol-1-ylphenyl)-1H-pyridin-2-oneIC50100000.0 [1]
5-(3-Chloro-4-fluorophenyl)-3-hydroxy-1H-pyridin-2-oneIC50100000.0 [1]
N-[4-(5-Hydroxy-6-oxo-1H-pyridin-3-yl)phenyl]acetamideIC50100000.0 [1]
3-Hydroxy-5-(1-methylindazol-6-yl)-1H-pyridin-2-oneIC50100000.0 [1]
7-Anilino-3-hydroxy-1H-quinazoline-2,4-dioneIC5030200.0 [1]
3-Hydroxy-7-pyrrolidin-1-yl-1H-quinazoline-2,4-dioneIC5027900.0 [1]
N-(3-Hydroxy-2,4-dioxo-1H-quinazolin-8-yl)acetamideIC50100000.0 [1]
N-(3-Hydroxy-2,4-dioxo-1H-quinazolin-6-yl)acetamideIC5087000.0 [1]
3-Hydroxy-6-phenyl-1H-pyrimidine-2,4-dioneIC50100000.0 [1]
N-[(3,4-Dihydroxyphenyl)methyl]benzamideIC50100000.0 [1]
N-[(E)-(2,5-Dibromo-3,4-dihydroxyphenyl)methylideneamino]-2-(3-methylanilino)acetamideIC50100000.0 [1]
Methyl 5,6-dihydroxy-2-phenylpyrimidine-4-carboxylateIC50100000.0 [1]
2-Anilino-N-[(E)-(3,4-dihydroxyphenyl)methylideneamino]acetamideIC50100000.0 [1]
4-[3-[(4-Chlorophenyl)methyl]-1,2,4-oxadiazol-5-yl]benzene-1,2-diolIC50100000.0 [1]
5-Hydroxy-N-methyl-6-oxo-2-thiophen-2-yl-1H-pyrimidine-4-carboxamideIC5067600.0 [1]
5-Hydroxy-6-oxo-N-propyl-2-thiophen-2-yl-1H-pyrimidine-4-carboxamideIC50100000.0 [1]
5-Hydroxy-N-(2-hydroxyethyl)-6-oxo-2-thiophen-2-yl-1H-pyrimidine-4-carboxamideIC50100000.0 [1]
N-Butan-2-yl-5-hydroxy-6-oxo-2-thiophen-2-yl-1H-pyrimidine-4-carboxamideIC50100000.0 [1]
N-(2-Acetamidoethyl)-5-hydroxy-6-oxo-2-thiophen-2-yl-1H-pyrimidine-4-carboxamideIC5062600.0 [1]
5-Hydroxy-6-oxo-N-pyridin-3-yl-2-thiophen-2-yl-1H-pyrimidine-4-carboxamideIC50100000.0 [1]
5-Hydroxy-N-(2-morpholin-4-ylethyl)-6-oxo-2-thiophen-2-yl-1H-pyrimidine-4-carboxamideIC5058900.0 [1]
3-Hydroxy-1-methylquinazoline-2,4(1H,3H)-dioneIC50100000.0 [1]
N-(3-Hydroxy-2,4-dioxo-1H-quinazolin-7-yl)acetamideIC50100000.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Deoxyribonuclease-1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.20 Nov2024https://www.aatbio.com/data-sets/deoxyribonuclease-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024November 20). Quest Database™ Deoxyribonuclease-1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/deoxyribonuclease-1-inhibitors-ic50-ki.
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