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DCN1-like protein 1 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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1-Benzyl-1-(1-pentan-2-ylpiperidin-4-yl)-3-[3-(trifluoromethyl)phenyl]ureaIC5050.0 [1], 62.0 [2]
3-(1-Benzylpiperidin-4-yl)-1-phenylureaIC5067000.0 [1]
1-(1,3-Benzodioxol-5-yl)-3-(1-benzylpiperidin-4-yl)ureaIC5067000.0 [1]
1-[[3-Fluoro-5-(trifluoromethyl)phenyl]methyl]-1-(1-propylpiperidin-4-yl)-3-[3-(trifluoromethyl)phenyl]ureaIC501000.0 [1]
1-(1,3-Benzodioxol-5-ylmethyl)-1-(1-tert-butylpiperidin-4-yl)-3-[3-(trifluoromethyl)phenyl]ureaIC50310.0 [1]
1-Benzyl-1-piperidin-4-yl-3-[3-(trifluoromethyl)phenyl]ureaIC5021000.0 [1]
1-Benzyl-1-[1-(cyclopropylmethyl)piperidin-4-yl]-3-[3-(trifluoromethyl)phenyl]ureaIC50210.0 [1]
1-Benzyl-1-(1-propylpiperidin-4-yl)-3-[3-(trifluoromethyl)phenyl]ureaIC50820.0 [1]
1-(Furan-2-ylmethyl)-1-(1-propylpiperidin-4-yl)-3-[3-(trifluoromethyl)phenyl]ureaIC50750.0 [1]
N-[(2H-1,3-Benzodioxol-5-yl)methyl]-N-(1-propylpiperidin-4-yl)-N'-[3-(trifluoromethyl)phenyl]ureaIC501100.0 [1]
1-Benzyl-1-(1-butylpiperidin-4-yl)-3-[3-(trifluoromethyl)phenyl]ureaIC50260.0 [1]
NAcM-OPTIC5045.0 [1]
1-(1,3-Benzodioxol-5-ylmethyl)-1-(1-butylpiperidin-4-yl)-3-[3-(trifluoromethyl)phenyl]ureaIC50360.0 [1]
1-(1-Benzylpiperidin-4-yl)-3-[3-(trifluoromethyl)phenyl]ureaIC507600.0 [1]
1-Benzyl-1-(1-benzylpiperidin-4-yl)-3-[3-(trifluoromethyl)phenyl]ureaIC503200.0 [1]
1-[1-[(4-Methylphenyl)methyl]piperidin-4-yl]-3-[3-(trifluoromethyl)phenyl]ureaIC5019000.0 [1]
1-Benzyl-1-[1-(3-methylbutyl)piperidin-4-yl]-3-[3-(trifluoromethyl)phenyl]ureaIC50790.0 [1]
1-Benzyl-1-[1-(3,3-dimethylbutyl)piperidin-4-yl]-3-[3-(trifluoromethyl)phenyl]ureaIC50170.0 [1]
1-Benzyl-1-[1-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)piperidin-4-yl]-3-[3-(trifluoromethyl)phenyl]ureaIC50360.0 [1]
1-Benzyl-1-[1-(2,2-dimethylpropyl)piperidin-4-yl]-3-[3-(trifluoromethyl)phenyl]ureaIC50960.0 [1]
1-(1-Benzylpiperidin-4-yl)-3-[3-(morpholin-4-ylmethyl)phenyl]ureaIC5067000.0 [1]
1-Propyl-1-(1-propylpiperidin-4-yl)-3-[3-(trifluoromethyl)phenyl]ureaIC5010000.0 [1]
1-(2-Methylpropyl)-1-(1-propylpiperidin-4-yl)-3-[3-(trifluoromethyl)phenyl]ureaIC505800.0 [1]
1-(3-Methylbutyl)-1-(1-propylpiperidin-4-yl)-3-[3-(trifluoromethyl)phenyl]ureaIC502700.0 [1]
1-Benzyl-3-[3-(trifluoromethyl)phenyl]-1-[1-(3,3,3-trifluoropropyl)piperidin-4-yl]ureaIC5023000.0 [1]
1-Benzyl-1-(1-propylsulfonylpiperidin-4-yl)-3-[3-(trifluoromethyl)phenyl]ureaIC50740.0 [1]
1-Benzyl-1-[1-(cyclohexylmethyl)piperidin-4-yl]-3-[3-(trifluoromethyl)phenyl]ureaIC50620.0 [1]
1-[1-[(4-Fluorophenyl)methyl]piperidin-4-yl]-3-[3-(trifluoromethyl)phenyl]ureaIC5014000.0 [1]
1-[1-[(2-Chlorophenyl)methyl]piperidin-4-yl]-3-[3-(trifluoromethyl)phenyl]ureaIC5028000.0 [1]
1-(2-Methoxyethyl)-1-(1-propylpiperidin-4-yl)-3-[3-(trifluoromethyl)phenyl]ureaIC5021000.0 [1]
1-[1-[(2-Methylphenyl)methyl]piperidin-4-yl]-3-[3-(trifluoromethyl)phenyl]ureaIC504000.0 [1]
1-Benzyl-1-(1-pentylpiperidin-4-yl)-3-[3-(trifluoromethyl)phenyl]ureaIC50660.0 [1]
1-[1-[(3-Fluorophenyl)methyl]piperidin-4-yl]-3-[3-(trifluoromethyl)phenyl]ureaIC5016000.0 [1]
1-(1-Benzylpiperidin-4-yl)-3-[3-(2-methylpyrazol-3-yl)phenyl]ureaIC5067000.0 [1]
1-Benzyl-1-(1-prop-2-enoylpiperidin-4-yl)-3-[3-(trifluoromethyl)phenyl]ureaIC5036000.0 [1]
1-Benzyl-1-[1-[(4-fluorophenyl)methyl]piperidin-4-yl]-3-[3-(trifluoromethyl)phenyl]ureaIC5010000.0 [1]
1-Benzyl-1-[1-(1,3-thiazol-2-ylmethyl)piperidin-4-yl]-3-[3-(trifluoromethyl)phenyl]ureaIC5067000.0 [1]
1-Benzyl-1-[1-(1H-pyrazol-5-ylmethyl)piperidin-4-yl]-3-[3-(trifluoromethyl)phenyl]ureaIC502400.0 [1]
1-[1-[(2-Fluorophenyl)methyl]piperidin-4-yl]-3-[3-(trifluoromethyl)phenyl]ureaIC5013000.0 [1]
1-(1-Propylpiperidin-4-yl)-1-(pyridin-3-ylmethyl)-3-[3-(trifluoromethyl)phenyl]ureaIC501300.0 [1]
1-Benzyl-1-[1-(1H-imidazol-5-ylmethyl)piperidin-4-yl]-3-[3-(trifluoromethyl)phenyl]ureaIC505900.0 [1]
1-(Cyclohexylmethyl)-1-(1-propylpiperidin-4-yl)-3-[3-(trifluoromethyl)phenyl]ureaIC502400.0 [1]
1-(1-Propylpiperidin-4-yl)-1-(pyridin-4-ylmethyl)-3-[3-(trifluoromethyl)phenyl]ureaIC504200.0 [1]
1-[1-[(3-Chlorophenyl)methyl]piperidin-4-yl]-3-[3-(trifluoromethyl)phenyl]ureaIC5033000.0 [1]
1-Benzyl-1-(1-butanoylpiperidin-4-yl)-3-[3-(trifluoromethyl)phenyl]ureaIC5036000.0 [1]
1-Benzyl-1-[1-(cyclopentylmethyl)piperidin-4-yl]-3-[3-(trifluoromethyl)phenyl]ureaIC50370.0 [1]
1-[1-[(3-Methylphenyl)methyl]piperidin-4-yl]-3-[3-(trifluoromethyl)phenyl]ureaIC506600.0 [1]
1-[1-[(4-Chlorophenyl)methyl]piperidin-4-yl]-3-[3-(trifluoromethyl)phenyl]ureaIC5025000.0 [1]
1-Butyl-1-(1-propylpiperidin-4-yl)-3-[3-(trifluoromethyl)phenyl]ureaIC501400.0 [1]
1-(1-Benzoylpiperidin-4-yl)-3-[3-(trifluoromethyl)phenyl]ureaIC5067000.0 [1]
1-Benzyl-3-[3-fluoro-5-(trifluoromethyl)phenyl]-1-[1-[(3-methoxyphenyl)methyl]piperidin-4-yl]ureaIC5028000.0 [1]
1-Benzyl-3-[3-fluoro-5-(trifluoromethyl)phenyl]-1-[1-[(2-methoxyphenyl)methyl]piperidin-4-yl]ureaIC5025000.0 [1]
1-[1-(1,3-Benzodioxol-5-ylmethyl)piperidin-4-yl]-1-benzyl-3-[3-(trifluoromethyl)phenyl]ureaIC5012000.0 [1]
1-Benzyl-3-(3,4-difluorophenyl)-1-(1-pentan-2-ylpiperidin-4-yl)ureaIC50817.0 [1]
1-Benzyl-3-[4-cyano-3-(trifluoromethyl)phenyl]-1-(1-pentan-2-ylpiperidin-4-yl)ureaIC50260.0 [1]
1-Benzyl-3-(3-chloro-5-fluorophenyl)-1-(1-pentan-2-ylpiperidin-4-yl)ureaIC50481.0 [1]
1-Benzyl-3-[3-fluoro-5-(trifluoromethyl)phenyl]-1-[1-[(1-methylimidazol-2-yl)methyl]piperidin-4-yl]ureaIC5028000.0 [1]
1-Benzyl-3-[3-fluoro-5-(trifluoromethyl)phenyl]-1-[1-(pyridin-4-ylmethyl)piperidin-4-yl]ureaIC5028000.0 [1]
1-Benzyl-3-(5-chloro-2-fluorophenyl)-1-(1-pentan-2-ylpiperidin-4-yl)ureaIC5034000.0 [1]
[(3S,4S)-1-Benzyl-4-[[3-(trifluoromethyl)phenyl]carbamoylamino]piperidin-3-yl] acetateIC5012000.0 [1]
1-Benzyl-3-[3-fluoro-5-(trifluoromethyl)phenyl]-1-(1-pentan-2-ylpiperidin-4-yl)ureaIC5058.0 [1]
1-Benzyl-3-(2,3-dihydro-1H-inden-5-yl)-1-(1-pentan-2-ylpiperidin-4-yl)ureaIC5077.0 [1]
1-Benzyl-1-(1-butylpiperidin-4-yl)-3-[4-fluoro-3-(trifluoromethyl)phenyl]ureaIC50612.0 [1]
1-Benzyl-3-(4-bromophenyl)-1-(1-pentan-2-ylpiperidin-4-yl)ureaIC5068.0 [1]
1-Benzyl-3-naphthalen-2-yl-1-(1-pentan-2-ylpiperidin-4-yl)ureaIC5018.0 [1]
1-Benzyl-1-(1-butylpiperidin-4-yl)-3-(3-chloro-4-methylphenyl)ureaIC50325.0 [1]
1-Benzyl-3-(4-iodophenyl)-1-(1-pentan-2-ylpiperidin-4-yl)ureaIC5054.0 [1]
1-Benzyl-3-[4-fluoro-3-(trifluoromethyl)phenyl]-1-(1-pentan-2-ylpiperidin-4-yl)ureaIC50290.0 [1]
1-Benzyl-1-(1-butylpiperidin-4-yl)-3-[2-fluoro-3-(trifluoromethyl)phenyl]ureaIC50583.0 [1]
3-(1,3-Benzothiazol-6-yl)-1-benzyl-1-(1-pentan-2-ylpiperidin-4-yl)ureaIC50626.0 [1]
1-Benzyl-3-(3-fluorophenyl)-1-(1-pentan-2-ylpiperidin-4-yl)ureaIC501690.0 [1]
1-Benzyl-1-(1-pentan-2-ylpiperidin-4-yl)-3-(4-propan-2-ylphenyl)ureaIC50654.0 [1]
1-Benzyl-1-[1-(pyridin-3-ylmethyl)piperidin-4-yl]-3-[3-(trifluoromethyl)phenyl]ureaIC5020000.0 [1]
1-Benzyl-3-[2-methyl-6-(trifluoromethyl)pyridin-3-yl]-1-(1-pentan-2-ylpiperidin-4-yl)ureaIC5013300.0 [1]
1-Benzyl-3-[3-fluoro-5-(trifluoromethyl)phenyl]-1-[1-(3-phenylpropyl)piperidin-4-yl]ureaIC503210.0 [1]
3-(1,3-Benzodioxol-5-yl)-1-benzyl-1-(1-pentan-2-ylpiperidin-4-yl)ureaIC50990.0 [1]
1-Benzyl-1-(1-butylpiperidin-4-yl)-3-(3,5-difluorophenyl)ureaIC504270.0 [1]
1-Benzyl-1-(1-butylpiperidin-4-yl)-3-(3-fluorophenyl)ureaIC503570.0 [1]
1-Benzyl-3-(4-bromo-2-methylphenyl)-1-(1-pentan-2-ylpiperidin-4-yl)ureaIC509430.0 [1]
1-Benzyl-1-[1-[(3-chloro-5-ethoxy-4-hydroxyphenyl)methyl]piperidin-4-yl]-3-[3-(trifluoromethyl)phenyl]ureaIC5067000.0 [1]
1-Benzyl-1-[1-[(4-benzylphenyl)methyl]piperidin-4-yl]-3-[3-fluoro-5-(trifluoromethyl)phenyl]ureaIC5022000.0 [1]
1-Benzyl-1-(1-butylpiperidin-4-yl)-3-(3-chlorophenyl)ureaIC50358.0 [1]
1-Benzyl-1-(1-butylpiperidin-4-yl)-3-(3-chloro-4-fluorophenyl)ureaIC501090.0 [1]
1-Benzyl-3-[3-fluoro-5-(trifluoromethyl)phenyl]-1-[1-[(E)-3-phenylprop-2-enyl]piperidin-4-yl]ureaIC504270.0 [1]
1-Benzyl-3-[3-fluoro-5-(trifluoromethyl)phenyl]-1-[1-(oxolan-3-ylmethyl)piperidin-4-yl]ureaIC504490.0 [1]
1-Benzyl-3-[2-fluoro-5-(trifluoromethyl)phenyl]-1-(1-pentan-2-ylpiperidin-4-yl)ureaIC507440.0 [1]
1-Benzyl-1-(1-butylpiperidin-4-yl)-3-[3-fluoro-5-(trifluoromethyl)phenyl]ureaIC50256.0 [1]
1-Benzyl-3-(3-fluoro-4-methylphenyl)-1-(1-pentan-2-ylpiperidin-4-yl)ureaIC50241.0 [1]
1-Benzyl-1-(1-pentan-2-ylpiperidin-4-yl)-3-[4-(trifluoromethyl)phenyl]ureaIC50314.0 [1]
1-Benzyl-3-(4-methylphenyl)-1-(1-pentan-2-ylpiperidin-4-yl)ureaIC50356.0 [1]
1-Benzyl-1-(1-butylpiperidin-4-yl)-3-(3-methylphenyl)ureaIC501300.0 [1]
1-Benzyl-3-[3-fluoro-5-(trifluoromethyl)phenyl]-1-[1-(3-methylsulfanylbutyl)piperidin-4-yl]ureaIC501790.0 [1]
1-Benzyl-3-[3-fluoro-5-(trifluoromethyl)phenyl]-1-[1-[(1-methylindol-5-yl)methyl]piperidin-4-yl]ureaIC5021000.0 [1]
1-Benzyl-1-(1-pentan-2-ylpiperidin-4-yl)-3-quinolin-6-ylureaIC5020000.0 [1]
1-Benzyl-3-[3-fluoro-5-(trifluoromethyl)phenyl]-1-[1-[(3-methylimidazol-4-yl)methyl]piperidin-4-yl]ureaIC5024000.0 [1]
1-[1-(1,3-Benzothiazol-2-ylmethyl)piperidin-4-yl]-1-benzyl-3-[3-fluoro-5-(trifluoromethyl)phenyl]ureaIC5025000.0 [1]
1-Benzyl-3-(4-chlorophenyl)-1-(1-pentan-2-ylpiperidin-4-yl)ureaIC50112.0 [1]
1-Benzyl-1-(1-butylpiperidin-4-yl)-3-(3-cyanophenyl)ureaIC504250.0 [1]
1-Benzyl-3-[3-fluoro-5-(trifluoromethyl)phenyl]-1-[1-[(3-phenoxyphenyl)methyl]piperidin-4-yl]ureaIC5024000.0 [1]
1-Benzyl-3-[3-fluoro-5-(trifluoromethyl)phenyl]-1-[1-[(5-methylfuran-2-yl)methyl]piperidin-4-yl]ureaIC5024000.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ DCN1-like protein 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/dcn1-like-protein-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 22). Quest Database™ DCN1-like protein 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/dcn1-like-protein-1-inhibitors-ic50-ki.
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