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D-amino-acid oxidase Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
4H-Thieno[3,2-b]pyrrole-5-carboxylic acidIC5011.9 [1]
4H-Thieno[3,2-b]pyrrole-5-carboxylic acidKi3.5 [1]
Benzoic acidIC502089.3 [1], 65700.0 [2], 134000.0 [3]
Benzoic acidKi2000.0 [1], 7000.0 [2], 10900.0 [3], 54000.0 [4]
4H-Furo[3,2-b]pyrrole-5-carboxylic acidIC509.0 [1], 17.2 [2], 141.0 [3], 214.0 [4]
4H-Furo[3,2-b]pyrrole-5-carboxylic acidKi35.5 [1]
6-[2-(3,5-Difluorophenyl)ethyl]-4-hydroxypyridazin-3(2H)-oneIC501.5 [1], 7.0 [2], 11.0 [3]
3-Hydroxy-5-(2-Phenylethyl)pyridin-2(1h)-OneIC503.9 [1], 20.0 [2], 140.0 [3]
6-[2-(3-Fluorophenyl)ethyl]-4-hydroxypyridazin-3(2H)-oneIC501.4 [1], 6.0 [2], 9.7 [3]
4-Hydroxy-6-{2-[3-(trifluoromethyl)phenyl]ethyl}pyridazin-3(2H)-oneIC502.4 [1], 8.3 [2], 16.0 [3]
6-[2-(4-Chlorophenyl)ethyl]-4-hydroxypyridazin-3(2H)-oneIC502.7 [1], 6.3 [2], 13.0 [3]
6-[2-(4-Fluorophenyl)ethyl]-4-hydroxypyridazin-3(2H)-oneIC503.1 [1], 7.2 [2], 10.0 [3]
4-Hydroxy-6-{2-[2-(trifluoromethyl)phenyl]ethyl}pyridazin-3(2H)-oneIC508.4 [1], 14.0 [2], 45.0 [3]
6-[2-(2-Fluorophenyl)ethyl]-4-hydroxypyridazin-3(2H)-oneIC502.0 [1], 4.4 [2], 13.0 [3]
6-(2-Cyclohexylethyl)-4-hydroxypyridazin-3(2H)-oneIC504.7 [1], 9.8 [2], 10.0 [3], 31.0 [4]
4-Hydroxy-6-(1-phenylethyl)pyridazin-3(2H)-oneIC504.9 [1], 11.0 [2], 32.0 [3]
Unii-76IC00yrvrIC5012.0 [1], 19.0 [2], 27.0 [3]
3-Hydroxyquinolin-2(1h)-OneIC504.0 [1], 6.9 [2], 42.0 [3], 43.0 [4]
6-Chlorobenzo[d]isoxazol-3-olIC5017.2 [1], 27.0 [2], 110.0 [3], 507.0 [4]
6-{2-[3,5-Bis(Trifluoromethyl)phenyl]ethyl}-4-hydroxy-2,3-dihydropyridazin-3-oneIC5057.0 [1], 63.0 [2], 250.0 [3]
6-(Phenoxymethyl)-1,2-dihydropyridazine-3,4-dioneIC502.2 [1], 5.1 [2]
3-HydroxycoumarinIC5034.67 [1]
3-HydroxycoumarinKi13.0 [1], 156.0 [2]
5-Methyl-1H-pyrazole-3-carboxylic acidIC50473.0 [1], 910.0 [2]
4-(4-Chlorophenethyl)-1H-pyrrole-2-carboxylic acidIC5011.48 [1], 238.0 [2]
4-(4-Chlorophenethyl)-1H-pyrrole-2-carboxylic acidKi7.2 [1]
3-Hydroxy-6-(2-Phenylethyl)pyridazin-4(1h)-OneIC502.4 [1], 3.8 [2], 10.0 [3]
6-(3-Phenylpropyl)-1,2-dihydropyridazine-3,4-dioneIC5013.0 [1], 233.0 [2]
6-[2-(2,4-Difluorophenyl)ethyl]-4-hydroxypyridazin-3(2H)-oneIC502.2 [1], 5.5 [2], 13.0 [3]
Malonic acidIC5010000000.0 [1]
3-Hydroxycinnamic acidIC506269000.0 [1], 10000000.0 [2]
3-Thiophenecarboxylic acidIC504400.0 [1]
3-Thiophenecarboxylic acidKi8160.0 [1]
Crotonic acidIC50357000.0 [1], 598000.0 [2]
5-Chloro-2,3-pyridinediolIC5047.0 [1], 930.0 [2]
5-Aminonicotinic acidIC502500000.0 [1]
4,5,6,7-Tetrahydrobenzo[b]thiophene-2-carboxylic acidIC50900000.0 [1], 1450000.0 [2]
5-Phenyl-1,3,4-oxadiazol-2-olIC50253000.0 [1], 365000.0 [2]
5-Chloro-3-hydroxyquinolin-2(1H)-oneIC504.0 [1], 9.0 [2]
2-(Naphthalen-1-ylmethyl)-1,2,4-triazinane-3,5,6-trioneIC5050.0 [1]
2-(Naphthalen-1-ylmethyl)-1,2,4-triazinane-3,5,6-trioneKi60.0 [1]
5-Chloro-6-fluoro-3-hydroxyquinolin-2(1H)-oneIC505.0 [1], 8.2 [2]
5,6-Dihydro-4H-cyclopenta[b]thiophene-2-carboxylic acidIC5059800.0 [1]
5,6-Dihydro-4H-cyclopenta[b]thiophene-2-carboxylic acidKi9920.0 [1]
5-(2-Methylphenyl)-3H-1,3,4-oxadiazol-2-oneIC50199000.0 [1], 298000.0 [2]
5,6-Dichloro-1,2-benzoxazol-3-olIC503.09 [1]
5,6-Dichloro-1,2-benzoxazol-3-olKi1.7 [1]
4-Ethyl-5-propylthiophene-2-carboxylic acidIC507905000.0 [1], 10000000.0 [2]
4-Ethyl-5-methylthiophene-2-carboxylic acidIC50666000.0 [1], 1104000.0 [2]
5-Methyl-4-propylthiophene-2-carboxylic acidIC501832000.0 [1], 3725000.0 [2]
3-(2-Phenylethyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acidIC50218.78 [1]
3-(2-Phenylethyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acidKi190.0 [1]
6-[(E)-2-(4-Chlorophenyl)ethenyl]-1,2-dihydropyridazine-3,4-dioneIC50120.0 [1], 570.0 [2]
6-Cyclohexyl-1,2-dihydropyridazine-3,4-dioneIC50300.0 [1], 1000.0 [2]
6-(3,3-Dimethylbutyl)-1,2-dihydropyridazine-3,4-dioneIC50670.0 [1], 1000.0 [2]
6-[2-(3-Methoxyphenyl)ethyl]-1,2-dihydropyridazine-3,4-dioneIC502.1 [1], 8.8 [2]
6-[2-(3,5-Dimethoxyphenyl)ethyl]-1,2-dihydropyridazine-3,4-dioneIC5013.0 [1], 25.0 [2]
6-[2-(4-Methoxyphenyl)ethyl]-1,2-dihydropyridazine-3,4-dioneIC502.9 [1], 10.0 [2]
2-Methyl-1,2,4-triazinane-3,5,6-trioneIC502800.0 [1], 3100.0 [2]
6-[(E)-2-Phenylethenyl]-1,2-dihydropyridazine-3,4-dioneIC502.4 [1], 3.8 [2]
6-[(2-Fluorophenoxy)methyl]-1,2-dihydropyridazine-3,4-dioneIC503.5 [1], 8.9 [2]
6-[2-[3-(Hydroxymethyl)phenyl]ethyl]-1,2-dihydropyridazine-3,4-dioneIC502.1 [1], 8.8 [2]
6-[2-[4-(Hydroxymethyl)phenyl]ethyl]-1,2-dihydropyridazine-3,4-dioneIC502.9 [1], 10.0 [2]
6-[2-[3-(Hydroxymethyl)-5-methoxyphenyl]ethyl]-1,2-dihydropyridazine-3,4-dioneIC5013.0 [1], 25.0 [2]
6-[2-(4-Tert-butylphenyl)ethyl]-1,2-dihydropyridazine-3,4-dioneIC506.6 [1], 18.0 [2]
6-[[4-(Hydroxymethyl)phenyl]sulfanylmethyl]-1,2-dihydropyridazine-3,4-dioneIC505.2 [1], 12.0 [2]
6-[(4-Fluorophenoxy)methyl]-1,2-dihydropyridazine-3,4-dioneIC502.9 [1], 13.0 [2]
6-[(3-Fluorophenoxy)methyl]-1,2-dihydropyridazine-3,4-dioneIC502.3 [1], 13.0 [2]
6-[2-[4-(3,3-Difluoroprop-1-ynyl)phenyl]ethyl]-1,2-dihydropyridazine-3,4-dioneIC508.1 [1], 18.0 [2]
6-[2-(4-Methylphenyl)ethyl]-1,2-dihydropyridazine-3,4-dioneIC506.1 [1], 14.0 [2]
6-[2-(4-Phenylphenyl)ethyl]-1,2-dihydropyridazine-3,4-dioneIC501.2 [1], 16.0 [2]
6-[2-(3-Methylphenyl)ethyl]-1,2-dihydropyridazine-3,4-dioneIC502.5 [1], 4.6 [2]
6-[2-(2-Methylphenyl)ethyl]-1,2-dihydropyridazine-3,4-dioneIC503.3 [1], 8.4 [2]
6-(2-Naphthalen-1-ylethyl)-1,2-dihydropyridazine-3,4-dioneIC502.3 [1], 8.8 [2]
6-(4-Phenylbutyl)-1,2-dihydropyridazine-3,4-dioneIC502.5 [1], 11.0 [2]
3(2H)-Pyridazinone, 6-butyl-4-hydroxy-IC506.9 [1], 13.0 [2]
NorepinephrineIC5010000000.0 [1]
Nicotinic acidIC501125000.0 [1]
CeftriaxoneIC5010000.0 [1]
Kojic acidIC502000.0 [1]
2-Thiophenecarboxylic acidIC507800.0 [1]
3-Aminobenzoic acidIC50392000.0 [1]
3-AminopyridineIC5010000000.0 [1]
Pyrrole-2-carboxylic acidIC505000.0 [1]
2,3-DihydroxypyridineIC501150.0 [1]
Indole-2-carboxylic acidIC50745.0 [1]
3-Hydroxypicolinic acidIC502478000.0 [1]
2-HydroxybenzimidazoleIC50100000.0 [1]
MofegilineIC5010000.0 [1]
5-Chlorosalicylic acidIC503671000.0 [1]
Mesotartaric acidIC5010000000.0 [1]
AdrenaloneIC501000000.0 [1]
5-Fluorosalicylic acidIC501045000.0 [1]
2-Aminonicotinic acidIC501000000.0 [1]
3-Aminopicolinic acidIC501000000.0 [1]
3-Hydroxyindolin-2-oneIC50100000.0 [1]
6-Aminonicotinic acidIC502500000.0 [1]
Benzo[d]isoxazol-3-olIC50418.0 [1]
5-Hydroxynicotinic acidIC5010000000.0 [1]
7-ChloroisatinIC507870.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ D-amino-acid oxidase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/d-amino-acid-oxidase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ D-amino-acid oxidase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/d-amino-acid-oxidase-inhibitors-ic50-ki.
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