Cystine/glutamate transporter Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	L-Cysteine	IC50	116000.0 [1]
	L-Cysteine	Ki	59000.0 [1]
	(S)-4-Carboxyphenylglycine	IC50	5000.0 [1], 15000.0 [2]
	4-[(E)-N-(2,4-Dinitroanilino)-C-methylcarbonimidoyl]-5-methyl-1,2-oxazole-3-carboxylic acid	IC50	290000.0 [1]
	4-[(E)-N-(2,4-Dinitroanilino)-C-methylcarbonimidoyl]-5-methyl-1,2-oxazole-3-carboxylic acid	Ki	147000.0 [1]
	5-Methyl-4-[(E)-C-methyl-N-(4-nitroanilino)carbonimidoyl]-1,2-oxazole-3-carboxylic acid	IC50	127000.0 [1]
	5-Methyl-4-[(E)-C-methyl-N-(4-nitroanilino)carbonimidoyl]-1,2-oxazole-3-carboxylic acid	Ki	60000.0 [1]
	4-[(E)-N-[3,5-Bis(trifluoromethyl)anilino]-C-methylcarbonimidoyl]-5-methyl-1,2-oxazole-3-carboxylic acid	IC50	129000.0 [1]
	4-[(E)-N-[3,5-Bis(trifluoromethyl)anilino]-C-methylcarbonimidoyl]-5-methyl-1,2-oxazole-3-carboxylic acid	Ki	64000.0 [1]
	4-[(E)-N-(2,4-Dinitroanilino)-C-methylcarbonimidoyl]-5-(2-naphthalen-2-ylethyl)-1,2-oxazole-3-carboxylic acid	IC50	225000.0 [1]
	4-[(E)-N-(2,4-Dinitroanilino)-C-methylcarbonimidoyl]-5-(2-naphthalen-2-ylethyl)-1,2-oxazole-3-carboxylic acid	Ki	113000.0 [1]
	Sulfasalazine	IC50	30000.0 [1]
	Mesalamine	IC50	1000000.0 [1]
	Quisqualic acid	IC50	5000.0 [1]
	Sulfapyridine	IC50	1000000.0 [1]
	L-Homocysteic acid	IC50	35000.0 [1]
	Erastin	IC50	200.0 [1]
	L-Serine O-sulfate	IC50	26000.0 [1]
	Susalimod	IC50	70000.0 [1]
	2-Hydroxy-5-[2-[4-(pyridin-2-ylsulfamoyl)phenyl]ethynyl]benzoic acid	IC50	30000.0 [1]
	3-Phenylethynyl-benzoic acid	IC50	270000.0 [1]
	5-(Phenylazo)salicylic acid	IC50	200000.0 [1]
	Imidazole ketone erastin	IC50	30.0 [1]
	3-(5-Acetyl-2-propan-2-yloxyphenyl)-2-[[4-[2-(4-chlorophenoxy)acetyl]piperazin-1-yl]methyl]quinazolin-4-one	IC50	30.0 [1]
	2-[[4-[2-(4-Chlorophenoxy)acetyl]piperazin-1-yl]methyl]-3-[5-(2-piperazin-1-ylacetyl)-2-propan-2-yloxyphenyl]quinazolin-4-one	IC50	100.0 [1]
	2-[[4-[2-(4-Chlorophenoxy)acetyl]piperazin-1-yl]methyl]-3-[5-[2-(4-methylpiperazin-1-yl)acetyl]-2-propan-2-yloxyphenyl]quinazolin-4-one	IC50	300.0 [1]
	2-[[4-[2-(4-Chlorophenoxy)acetyl]piperazin-1-yl]methyl]-3-[5-(2-morpholin-4-ylacetyl)-2-propan-2-yloxyphenyl]quinazolin-4-one	IC50	10.0 [1]
	2-[[4-[2-(4-Chlorophenoxy)acetyl]piperazin-1-yl]methyl]-3-[2-propan-2-yloxy-5-[2-(4-prop-2-enylpiperazin-1-yl)acetyl]phenyl]quinazolin-4-one	IC50	10.0 [1]
	2-[[4-[2-(4-Chlorophenoxy)acetyl]piperazin-1-yl]methyl]-3-[5-[2-[4-[(4-methoxyphenyl)methyl]piperazin-1-yl]acetyl]-2-propan-2-yloxyphenyl]quinazolin-4-one	IC50	4.0 [1]
	2-[[4-[2-(4-Chlorophenoxy)acetyl]piperazin-1-yl]methyl]-3-[5-(2-fluoroacetyl)-2-propan-2-yloxyphenyl]quinazolin-4-one	IC50	40.0 [1]
	2-[[4-[2-(4-Chlorophenoxy)acetyl]piperazin-1-yl]methyl]-3-[2-propan-2-yloxy-5-(2,2,2-trifluoroacetyl)phenyl]quinazolin-4-one	IC50	20.0 [1]
	Methyl 2-hydroxy-5-[[4-[(2-pyridinylamino)sulfonyl]phenyl]ethynyl]benzoate	IC50	1000000.0 [1]
	2-Hydroxy-5-[(E)-2-[4-(pyridin-2-ylsulfamoyl)phenyl]ethenyl]benzoic acid	IC50	70000.0 [1]
	Methyl 2-hydroxy-5-[(E)-2-[4-(pyridin-2-ylsulfamoyl)phenyl]ethenyl]benzoate	IC50	900000.0 [1]
	2-Hydroxy-5-[2-[4-(pyridin-2-ylsulfamoyl)phenyl]ethyl]benzoic acid	IC50	700000.0 [1]
	2-Hydroxy-5-(phenylethynyl)benzoic acid	IC50	150000.0 [1]
	3-[3-Carboxy-5-[2-(1-naphthyl)ethyl]isoxazole-4-yl]-L-alanine	Ki	117000.0 [1]
	3-[3-Carboxy-5-[2-(2-naphthyl)ethyl]isoxazole-4-yl]-L-alanine	Ki	52000.0 [1]
	3-[2-[4-(Pyridin-2-ylsulfamoyl)phenyl]ethynyl]benzoic acid	IC50	75000.0 [1]
	3-[2-[4-(Pyridin-2-ylsulfamoyl)phenyl]ethyl]benzoic acid	IC50	920000.0 [1]
	Methyl 2-hydroxy-5-[2-[4-(pyridin-2-ylsulfamoyl)phenyl]ethyl]benzoate	IC50	1000000.0 [1]
	(R)-4-Carboxyphenylglycine	IC50	1000000.0 [1]
	Piperazine Erastin	IC50	800.0 [1]
	3-[2-[[4-[2-(4-Chlorophenoxy)acetyl]piperazin-1-yl]methyl]-4-oxoquinazolin-3-yl]-4-propan-2-yloxybenzaldehyde	IC50	60.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 44 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Cystine/glutamate transporter Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/cystine-glutamate-transporter-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 21). Quest Database™ Cystine/glutamate transporter Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/cystine-glutamate-transporter-inhibitors-ic50-ki.
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