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Cystathionine gamma-lyase Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
Aminooxyacetic acidIC50570.0 [1], 4000.0 [2]
PenicillamineIC50270000.0 [1]
L-PropargylglycineIC5040000.0 [1]
AviglycineIC501100.0 [1]
beta-Cyano-L-alanineIC5014000.0 [1]
AgathisflavoneIC50400000.0 [1]
CupressuflavoneIC50400000.0 [1]
Podocarpusflavone AIC50400000.0 [1]
Methyl N-[[(Z)-indol-3-ylidenemethyl]amino]carbamodithioateIC50100000.0 [1]
[1-(2-Pyridinyl)ethylidene]hydrazinecarbodithioic acid, methyl esterIC50100000.0 [1]
(2S,3R)-3-[(2S,3R)-5,7-Dihydroxy-2-(4-methoxyphenyl)-4-oxo-2,3-dihydrochromen-3-yl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-oneIC50400000.0 [1]
7-Amino-5-imino-1H-quinoline-2,8-dioneIC506300.0 [1]
5-Methylsulfanyl-2-pyridin-2-yl-2,3-dihydro-1,3,4-thiadiazoleIC506000.0 [1]
Methyl N-[(E)-pyridin-3-ylmethylideneamino]carbamodithioateIC5050000.0 [1]
[2-(4-Methoxyanilino)-2-oxoethyl] N-[(E)-(5-bromopyridin-2-yl)methylideneamino]carbamodithioateIC50100000.0 [1]
[2-(4-Tert-butylanilino)-2-oxoethyl] N-[(E)-(3-fluoropyridin-2-yl)methylideneamino]carbamodithioateIC502000.0 [1]
Methyl N-[(E)-pyrazin-2-ylmethylideneamino]carbamodithioateIC5015000.0 [1]
(2-Anilino-2-oxoethyl) N-[(E)-pyridin-2-ylmethylideneamino]carbamodithioateIC506000.0 [1]
Methyl N-[(E)-1H-pyrazol-5-ylmethylideneamino]carbamodithioateIC5015000.0 [1]
[2-Oxo-2-[4-(trifluoromethyl)anilino]ethyl] N-[(E)-(3-fluoropyridin-2-yl)methylideneamino]carbamodithioateIC506000.0 [1]
[2-(3-Bromoanilino)-2-oxoethyl] N-[(E)-pyridin-2-ylmethylideneamino]carbamodithioateIC50100000.0 [1]
(4S)-2-Oxo-N-prop-2-ynyl-1,3-thiazolidine-4-carboxamideIC5030000.0 [1]
[2-(4-Tert-butylanilino)-2-oxoethyl] N-[(E)-pyridin-3-ylmethylideneamino]carbamodithioateIC5012000.0 [1]
[2-(4-Methylanilino)-2-oxoethyl] N-[(E)-(4-chloro-1-methylpyrazol-3-yl)methylideneamino]carbamodithioateIC503000.0 [1]
Methyl N-[(E)-(6-bromopyridin-2-yl)methylideneamino]carbamodithioateIC5012000.0 [1]
[2-(4-Methylanilino)-2-oxoethyl] N-[(E)-(6-methylpyridin-2-yl)methylideneamino]carbamodithioateIC503500.0 [1]
[2-(4-Methoxyanilino)-2-oxoethyl] N-[(E)-1,3-thiazol-4-ylmethylideneamino]carbamodithioateIC502100.0 [1]
[2-(4-Tert-butylanilino)-2-oxoethyl] N-[(E)-pyridin-4-ylmethylideneamino]carbamodithioateIC5040000.0 [1]
[2-(4-Fluoroanilino)-2-oxoethyl] N-[(E)-pyridin-2-ylmethylideneamino]carbamodithioateIC50100000.0 [1]
Methyl N-[(E)-(3-methylpyridin-2-yl)methylideneamino]carbamodithioateIC506000.0 [1]
[2-(4-Methylanilino)-2-oxoethyl] N-[(E)-(6-bromopyridin-2-yl)methylideneamino]carbamodithioateIC5010000.0 [1]
[2-(4-Methoxyanilino)-2-oxoethyl] N-[(E)-pyridin-2-ylmethylideneamino]carbamodithioateIC502000.0 [1]
[2-(4-Methylanilino)-2-oxoethyl] N-[(E)-(3-methylpyridin-2-yl)methylideneamino]carbamodithioateIC502500.0 [1]
[2-(4-Methoxyanilino)-2-oxoethyl] N-[(E)-(4-chloro-1-methylpyrazol-3-yl)methylideneamino]carbamodithioateIC502700.0 [1]
[2-(4-Tert-butylanilino)-2-oxoethyl] N-[(E)-pyrazin-2-ylmethylideneamino]carbamodithioateIC50100000.0 [1]
[2-(4-Methoxyanilino)-2-oxoethyl] N-[(E)-(6-methylpyridin-2-yl)methylideneamino]carbamodithioateIC501900.0 [1]
Methyl N-[(E)-1,3-thiazol-4-ylmethylideneamino]carbamodithioateIC507000.0 [1]
[2-(4-Methylanilino)-2-oxoethyl] N-[(E)-(3-fluoropyridin-2-yl)methylideneamino]carbamodithioateIC502000.0 [1]
[2-(4-Methylanilino)-2-oxoethyl] N-[(E)-pyridin-2-ylmethylideneamino]carbamodithioateIC502000.0 [1]
[2-(4-Methylanilino)-2-oxoethyl] N-[(E)-pyridin-3-ylmethylideneamino]carbamodithioateIC5025000.0 [1]
Methyl N-[(E)-(5-bromopyridin-2-yl)methylideneamino]carbamodithioateIC5010000.0 [1]
Methyl N-[(E)-(4-chloro-1-methylpyrazol-3-yl)methylideneamino]carbamodithioateIC506000.0 [1]
[2-(4-Tert-butylanilino)-2-oxoethyl] N-[(E)-(6-bromopyridin-2-yl)methylideneamino]carbamodithioateIC5015000.0 [1]
[2-(4-Methoxyanilino)-2-oxoethyl] N-[(E)-(3-fluoropyridin-2-yl)methylideneamino]carbamodithioateIC501200.0 [1]
Methyl N-[(E)-(1-methylindol-2-yl)methylideneamino]carbamodithioateIC50100000.0 [1]
[2-(4-Tert-butylanilino)-2-oxoethyl] N-[(E)-(6-methylpyridin-2-yl)methylideneamino]carbamodithioateIC506000.0 [1]
[2-(4-Tert-butylanilino)-2-oxoethyl] N-[(E)-pyridin-2-ylmethylideneamino]carbamodithioateIC503000.0 [1]
[2-(4-Tert-butylanilino)-2-oxoethyl] N-[(E)-(4-chloro-1-methylpyrazol-3-yl)methylideneamino]carbamodithioateIC506000.0 [1]
Methyl N-[(E)-(3-fluoropyridin-2-yl)methylideneamino]carbamodithioateIC505000.0 [1]
Methyl N-[(E)-pyridin-2-ylmethylideneamino]carbamodithioateIC506000.0 [1]
Chembl4170257IC505000.0 [1]
(E)-Methyl 2-(pyridin-4-ylmethylene)hydrazinecarbodithioateIC5040000.0 [1]
8-[(2R,3S)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-2,3-dihydrochromen-3-yl]-7-hydroxy-2-(4-hydroxyphenyl)-5-methoxychromen-4-oneIC50400000.0 [1]
2'',4''-Di-O-(Z-p-coumaroyl)afzelinIC50400000.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Cystathionine gamma-lyase Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/cystathionine-gamma-lyase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Cystathionine gamma-lyase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/cystathionine-gamma-lyase-inhibitors-ic50-ki.
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