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Collagenase Inhibitors (IC50, Ki)

Structure
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▼
Compound Name
▲
▼
Standard Type
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▼
Standard Values (in nM)
▲
▼
N-Hydroxy-2-[(4-nitro-benzyl)-pentafluorobenzenesulfonyl-amino]-acetamideKi5.0 [1]
N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-(4-nitro-benzyl)-amino]-acetamideKi20.0 [1]
N-Hydroxy-2-[(4-nitro-benzyl)-(nonafluorobutane-1-sulfonyl)-amino]-acetamideKi12.0 [1]
NafamostatIC50420000.0 [1]
N-HydroxybenzenesulfonamideKi83000.0 [1]
(2S,3R)-3-(Cyclopentylmethyl)-N-hydroxy-4-oxo-4-piperidin-1-yl-2-[(3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl]butanamideIC507.0 [1]
N-Hydroxy-N~2~-[(4-Methoxyphenyl)sulfonyl]glycinamideKi120.0 [1]
2-[Benzyl-(4-methoxyphenyl)sulfonylamino]-N-hydroxy-3-methylbutanamideKi17.0 [1]
2-[Benzyl-(4-methoxyphenyl)sulfonylamino]-N-hydroxyacetamideKi27.0 [1]
N-Hydroxy-2,4,6-trimethylbenzenesulfonamideKi39000.0 [1]
2-[Benzyl-(4-methoxyphenyl)sulfonylamino]-N-hydroxypropanamideKi20.0 [1]
(2S)-N-Benzyl-5-(diaminomethylideneamino)-2-[[(2S)-2-[[1-[(2,6-dichlorophenyl)methyl]-3-(pyrrolidin-1-ylmethyl)indol-6-yl]carbamoylamino]-3-(4-methoxyphenyl)propanoyl]amino]pentanamideIC5046300.0 [1]
N-Hydroxy-2-[(2-nitro-benzyl)-(nonafluorobutane-1-sulfonyl)-amino]-propionamideKi10.0 [1]
N-Hydroxy-2-[(2-nitro-benzyl)-pentafluorobenzenesulfonyl-amino]-propionamideKi5.0 [1]
N-Hydroxy-2-[(4-nitro-benzyl)-(nonafluorobutane-1-sulfonyl)-amino]-propionamideKi11.0 [1]
N-Hydroxy-2-[(4-nitro-benzyl)-pentafluorobenzenesulfonyl-amino]-propionamideKi5.0 [1]
N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-(4-nitro-benzyl)-amino]-propionamideKi21.0 [1]
N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-(2-nitro-benzyl)-amino]-propionamideKi19.0 [1]
n-HydroxymethanesulfonamideKi100.0 [1]
2-[Benzyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]-N-hydroxyacetamideKi6.0 [1]
2-[(2-Chlorophenyl)methyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]-N-hydroxypropanamideKi5.0 [1]
N-Hydroxy-2-[(2,3,4,5,6-pentafluorophenyl)sulfonylamino]propanamideKi45.0 [1]
N-Hydroxy-4-methylbenzenesulfonamideKi88000.0 [1]
N-Hydroxy-2-(1,1,2,2,3,3,4,4,4-nonafluorobutylsulfonylamino)propanamideKi79.0 [1]
N-Hydroxy-2-(1,1,2,2,3,3,4,4,4-nonafluorobutylsulfonylamino)acetamideKi80.0 [1]
MMP-3 Inhibitor VIIIKi13.0 [1]
N-Hydroxy-2-[(4-methoxyphenyl)sulfonylamino]-4-methylpentanamideKi95.0 [1]
N-Hydroxy-2-[(2-nitrophenyl)methyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]acetamideKi6.0 [1]
N-Hydroxy-2-[(4-methoxyphenyl)sulfonylamino]propanamideKi130.0 [1]
N-Hydroxy-4-methyl-2-(1,1,2,2,3,3,4,4,4-nonafluorobutylsulfonylamino)pentanamideKi69.0 [1]
N-Hydroxy-3-methyl-2-(1,1,2,2,3,3,4,4,4-nonafluorobutylsulfonylamino)butanamideKi78.0 [1]
N-Hydroxy-2-[(2,3,4,5,6-pentafluorophenyl)sulfonylamino]acetamideKi54.0 [1]
2-[Benzyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]-N-hydroxy-4-methylpentanamideKi5.0 [1]
2-[Benzyl(1,1,2,2,3,3,4,4,4-nonafluorobutylsulfonyl)amino]-N-hydroxy-4-methylpentanamideKi8.0 [1]
N-Hydroxy-2-[(4-methoxyphenyl)sulfonyl-[(2-nitrophenyl)methyl]amino]acetamideKi24.0 [1]
N-Hydroxy-4-methyl-2-[(2,3,4,5,6-pentafluorophenyl)sulfonylamino]pentanamideKi38.0 [1]
2-[Benzyl(1,1,2,2,3,3,4,4,4-nonafluorobutylsulfonyl)amino]-N-hydroxyacetamideKi13.0 [1]
N-Hydroxy-3-methyl-2-[(2,3,4,5,6-pentafluorophenyl)sulfonylamino]butanamideKi40.0 [1]
N-Hydroxy-2-[(2-nitrophenyl)methyl-(1,1,2,2,3,3,4,4,4-nonafluorobutylsulfonyl)amino]acetamideKi13.0 [1]
2-[Benzyl(1,1,2,2,3,3,4,4,4-nonafluorobutylsulfonyl)amino]-N-hydroxypropanamideKi12.0 [1]
2-[Benzyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]-N-hydroxypropanamideKi6.0 [1]
2-[Benzyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]-N-hydroxy-3-methylbutanamideKi5.0 [1]
2-[Benzyl(1,1,2,2,3,3,4,4,4-nonafluorobutylsulfonyl)amino]-N-hydroxy-3-methylbutanamideKi10.0 [1]
2-[(2-Chlorophenyl)methyl-(1,1,2,2,3,3,4,4,4-nonafluorobutylsulfonyl)amino]-N-hydroxypropanamideKi11.0 [1]
2-[(2-Chlorophenyl)methyl-(4-methoxyphenyl)sulfonylamino]-N-hydroxypropanamideKi22.0 [1]
4-Chloro-N-hydroxybenzene-1-sulfonamideKi80000.0 [1]
N-Hydroxy-2-[(4-methoxyphenyl)sulfonylamino]-3-methylbutanamideKi103.0 [1]
N-Hydroxy-2-[(4-nitro-benzyl)-(3-trifluoromethyl-benzenesulfonyl)-amino]-acetamideKi5.0 [1]
N-Hydroxy-2-[(4-nitro-benzyl)-trifluoromethanesulfonyl-amino]-acetamideKi73.0 [1]
N-Hydroxy-2-[3-naphthalen-1-yl-1-(4-nitro-benzyl)-ureido]-acetamideKi18.0 [1]
N-Hydroxy-2-[(4-nitro-benzyl)-trichloromethanesulfonyl-amino]-acetamideKi70.0 [1]
2-[(3,4-Dichlorophenyl)carbamoyl-[(4-nitrophenyl)methyl]amino]-N-hydroxyacetamideKi11.0 [1]
N-Hydroxy-2-[(2-methylphenyl)sulfonylcarbamoyl-[(4-nitrophenyl)methyl]amino]acetamideKi10.0 [1]
2-[(3,5-Dichloro-2-hydroxyphenyl)sulfonyl-[(4-nitrophenyl)methyl]amino]-N-hydroxyacetamideKi9.0 [1]
N-Hydroxy-2-[(4-iodo-benzenesulfonyl)-(4-nitro-benzyl)-amino]-acetamideKi32.0 [1]
2-[[3-(Benzenesulfonylcarbamoylamino)phenyl]sulfonyl-[(4-nitrophenyl)methyl]amino]-N-hydroxyacetamideKi18.0 [1]
2-[[4-[(4-Chlorophenyl)sulfonylcarbamoylamino]phenyl]sulfonyl-[(4-nitrophenyl)methyl]amino]-N-hydroxyacetamideKi13.0 [1]
(2S)-N-Benzyl-5-(diaminomethylideneamino)-2-[[(2S)-2-[[1-[(4-fluorophenyl)methyl]-3-(pyrrolidin-1-ylmethyl)indol-6-yl]carbamoylamino]-3-phenylpropanoyl]amino]pentanamideIC5012700.0 [1]
2-[3-(3-Chloro-phenyl)-1-(4-nitro-benzyl)-ureido]-N-hydroxy-acetamideKi16.0 [1]
N-Hydroxy-2-[(naphthalene-2-sulfonyl)-(4-nitro-benzyl)-amino]-acetamideKi10.0 [1]
2-[[4-[(4-Methylphenyl)sulfonylcarbamoylamino]phenyl]sulfonyl-[(4-nitrophenyl)methyl]amino]acetic acidKi30.0 [1]
2-[3-(4-Fluoro-phenyl)-1-(4-nitro-benzyl)-ureido]-N-hydroxy-acetamideKi21.0 [1]
2-[(2,4-Difluorophenyl)carbamoyl-[(4-nitrophenyl)methyl]amino]-N-hydroxyacetamideKi13.0 [1]
N-Hydroxy-2-[(naphthalene-1-sulfonyl)-(4-nitro-benzyl)-amino]-acetamideKi15.0 [1]
N-Hydroxy-2-[(4-methylphenyl)sulfonylcarbamoyl-[(4-nitrophenyl)methyl]amino]acetamideKi12.0 [1]
{4-[Hydroxycarbamoylmethyl-(4-nitro-benzyl)-sulfamoyl]-phenyl}-carbamic acid tert-butyl esterKi9.0 [1]
2-[[4-[(4-Fluorophenyl)sulfonylcarbamoylamino]phenyl]sulfonyl-[(4-nitrophenyl)methyl]amino]acetic acidKi29.0 [1]
N-Hydroxy-2-[(2-nitro-benzenesulfonyl)-(4-nitro-benzyl)-amino]-acetamideKi18.0 [1]
2-[(2,4-Dinitro-phenylsulfanyl)-(4-nitro-benzyl)-amino]-N-hydroxy-acetamideKi12.0 [1]
N-Hydroxy-2-[[4-[(4-methylphenyl)sulfonylcarbamoylamino]phenyl]sulfonyl-[(4-nitrophenyl)methyl]amino]acetamideKi19.0 [1]
N-Hydroxy-2-[(4-nitro-benzyl)-(4-nitro-phenylsulfanyl)-amino]-acetamideKi13.0 [1]
N-Hydroxy-2-[(4-nitrophenyl)methyl-(2,4,6-trimethylphenyl)sulfonylamino]acetamideKi24.0 [1]
N-Hydroxy-2-[(4-nitro-benzenesulfonyl)-(4-nitro-benzyl)-amino]-acetamideKi13.0 [1]
2-[[3-[(4-Chlorophenyl)sulfonylcarbamoylamino]phenyl]sulfonyl-[(4-nitrophenyl)methyl]amino]acetic acidKi37.0 [1]
N-Hydroxy-3-(trifluoromethyl)benzenesulfonamideKi800.0 [1]
N-Hydroxy-2-[(4-nitro-benzyl)-(2-nitro-phenylsulfanyl)-amino]-acetamideKi10.0 [1]
2-[(4-Fluoro-benzenesulfonyl)-(4-nitro-benzyl)-amino]-N-hydroxy-acetamideKi42.0 [1]
2-[[4-(Benzenesulfonylcarbamoylamino)phenyl]sulfonyl-[(4-nitrophenyl)methyl]amino]acetic acidKi24.0 [1]
2-[[3-[(4-Methylphenyl)sulfonylcarbamoylamino]phenyl]sulfonyl-[(4-nitrophenyl)methyl]amino]acetic acidKi33.0 [1]
2-[Dimethylsulfamoyl-[(4-nitrophenyl)methyl]amino]-N-hydroxyacetamideKi79.0 [1]
2-[3-(4-Chloro-phenyl)-1-(4-nitro-benzyl)-ureido]-N-hydroxy-acetamideKi15.0 [1]
2-[3-Benzoyl-1-(4-nitro-benzyl)-thioureido]-N-hydroxy-acetamideKi6.0 [1]
{3-[Hydroxycarbamoylmethyl-(4-nitro-benzyl)-sulfamoyl]-phenyl}-carbamic acid tert-butyl esterKi9.0 [1]
2-[[3-[(4-Fluorophenyl)sulfonylcarbamoylamino]phenyl]sulfonyl-[(4-nitrophenyl)methyl]amino]acetic acidKi30.0 [1]
2-[[4-[(4-Fluorophenyl)sulfonylcarbamoylamino]phenyl]sulfonyl-[(4-nitrophenyl)methyl]amino]-N-hydroxyacetamideKi18.0 [1]
2-[[3-[(4-Fluorophenyl)sulfonylcarbamoylamino]phenyl]sulfonyl-[(4-nitrophenyl)methyl]amino]-N-hydroxyacetamideKi17.0 [1]
3-[Hydroxycarbamoylmethyl-(4-nitro-benzyl)-sulfamoyl]-benzoic acidKi10.0 [1]
4-[Hydroxycarbamoylmethyl-(4-nitro-benzyl)-sulfamoyl]-benzoic acidKi7.0 [1]
2-[(4-Chlorophenyl)sulfonylcarbamoyl-[(4-nitrophenyl)methyl]amino]-N-hydroxyacetamideKi9.0 [1]
2-[(4-Fluorophenyl)sulfonylcarbamoyl-[(4-nitrophenyl)methyl]amino]-N-hydroxyacetamideKi10.0 [1]
N-Hydroxy-2-[[3-[(2-methylphenyl)sulfonylcarbamoylamino]phenyl]sulfonyl-[(4-nitrophenyl)methyl]amino]acetamideKi23.0 [1]
2-[[3-[(4-Chlorophenyl)sulfonylcarbamoylamino]phenyl]sulfonyl-[(4-nitrophenyl)methyl]amino]-N-hydroxyacetamideKi21.0 [1]
2-[(4-Bromo-benzenesulfonyl)-(4-nitro-benzyl)-amino]-N-hydroxy-acetamideKi36.0 [1]
2-[[3-(Benzenesulfonylcarbamoylamino)phenyl]sulfonyl-[(4-nitrophenyl)methyl]amino]acetic acidKi28.0 [1]
N-Hydroxy-2-[[3-[(4-methylphenyl)sulfonylcarbamoylamino]phenyl]sulfonyl-[(4-nitrophenyl)methyl]amino]acetamideKi20.0 [1]
2-[(Heptadecafluorooctane-1-sulfonyl)-(4-nitro-benzyl)-amino]-N-hydroxy-acetamideKi8.0 [1]
(2S)-N-Benzyl-5-(diaminomethylideneamino)-2-[[(2S)-3-(4-methoxyphenyl)-2-[[3-(pyrrolidin-1-ylmethyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]indol-6-yl]carbamoylamino]propanoyl]amino]pentanamideIC5024200.0 [1]
2-[Benzenesulfonyl-(4-nitro-benzyl)-amino]-N-hydroxy-acetamideKi51.0 [1]
2-[(4-Chloro-benzenesulfonyl)-(4-nitro-benzyl)-amino]-N-hydroxy-acetamideKi41.0 [1]
2-[(2,5-Dichloro-benzenesulfonyl)-(4-nitro-benzyl)-amino]-N-hydroxy-acetamideKi16.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Collagenase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/collagenase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 22). Quest Database™ Collagenase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/collagenase-inhibitors-ic50-ki.
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