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Chymotrypsin-like protease CTRL-1 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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▼
Standard Values (in nM)
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▼
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-hydroxypropanoyl]amino]propanoyl]amino]-3-methylbutanoyl]amino]-N-[(2S)-1-(1H-imidazol-5-yl)-3-oxopropan-2-yl]-4-methylpentanamideIC505700.0 [1]
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-hydroxypropanoyl]amino]propanoyl]amino]-3-methylbutanoyl]amino]-N-[(2S)-5-(dimethylamino)-1,5-dioxopentan-2-yl]-4-methylpentanamideIC5037000.0 [1]
(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-hydroxypropanoyl]amino]propanoyl]amino]-N-[(2S)-3-cyclohexyl-1-[[(2S)-1-(1H-imidazol-5-yl)-3-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-3-methylbutanamideIC5065.0 [1]
N-[5-[[Amino(nitramido)methylidene]amino]-1-[(4-methyl-1-oxopentan-2-yl)amino]-1-oxopentan-2-yl]-2-cyclopentyl-10-(1,3-dioxoisoindol-2-yl)decanamideIC502.0 [1]
(2S)-2-[[(2S,3R)-2-Acetamido-3-hydroxybutanoyl]amino]-N-[(2S)-3-cyclohexyl-1-[[(2S)-1-(1H-imidazol-5-yl)-3-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-3-methylbutanamideIC5098.0 [1]
Ethyl (E,4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-hydroxypropanoyl]amino]propanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]-7-(dimethylamino)-7-oxohept-2-enoateIC50330000.0 [1]
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-hydroxypropanoyl]amino]propanoyl]amino]-3-methylbutanoyl]amino]-4-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]pentanamideIC503000000.0 [1]
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-hydroxypropanoyl]amino]propanoyl]amino]-3-methylbutanoyl]amino]-N-[(2S)-3,3-dimethyl-1-oxobutan-2-yl]-4-methylpentanamideIC503000000.0 [1]
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-hydroxypropanoyl]amino]propanoyl]amino]-3-methylbutanoyl]amino]-4-methyl-N-[(2S)-1-oxo-3-phenylpropan-2-yl]pentanamideIC502000000.0 [1]
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-hydroxypropanoyl]amino]propanoyl]amino]-3-methylbutanoyl]amino]-N-[(2S)-1-cyclohexyl-3-oxopropan-2-yl]-4-methylpentanamideIC5062000.0 [1]
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-hydroxypropanoyl]amino]propanoyl]amino]-3-methylbutanoyl]amino]-4-methyl-N-[(2S)-1-oxo-3-thiophen-2-ylpropan-2-yl]pentanamideIC5048000.0 [1]
(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-hydroxypropanoyl]amino]propanoyl]amino]-N-[(2S)-1-[[(2S)-1-(1H-imidazol-5-yl)-3-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-3-methylbutanamideIC50390.0 [1]
(2S)-2-Acetamido-N-[(2S)-1-[[(2S)-3-cyclohexyl-1-[[(2S)-1-(1H-imidazol-5-yl)-3-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]butanediamideIC5010000.0 [1]
(2S)-2-[[(2S)-2-Acetamido-3-hydroxypropanoyl]amino]-N-[(2S)-3-cyclohexyl-1-[[(2S)-1-(1H-imidazol-5-yl)-3-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-3-methylbutanamideIC50340.0 [1]
(2S)-2-[[(2S)-2-Acetamidopropanoyl]amino]-N-[(2S)-3-cyclohexyl-1-[[(2S)-1-(1H-imidazol-5-yl)-3-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-3-methylbutanamideIC50270.0 [1]
N-[5-[[Amino(nitramido)methylidene]amino]-1-[(4-methyl-1-oxopentan-2-yl)amino]-1-oxopentan-2-yl]-10-cyano-2-cyclopentyldecanamideIC506.0 [1]
N-[5-[[Amino(nitramido)methylidene]amino]-1-[[3-methyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butyl]amino]-1-oxopentan-2-yl]-10-cyano-2-cyclopentyldecanamideIC508.0 [1]
N-[5-[[Amino(nitramido)methylidene]amino]-1-[(1-chloro-5-methyl-2-oxohexan-3-yl)amino]-1-oxopentan-2-yl]-10-cyano-2-cyclopentyldecanamideIC501000.0 [1]
N-[5-[[Amino(nitramido)methylidene]amino]-1-[[1-(ethylamino)-5-methyl-1,2-dioxohexan-3-yl]amino]-1-oxopentan-2-yl]-10-cyano-2-cyclopentyldecanamideIC5013.0 [1]
Items per page: 1 - 10 of 19
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References

This online tool may be cited as follows

MLA

"Quest Database™ Chymotrypsin-like protease CTRL-1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Nov. 2024, https://www.aatbio.com/data-sets/chymotrypsin-like-protease-ctrl-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, November 21). Quest Database™ Chymotrypsin-like protease CTRL-1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/chymotrypsin-like-protease-ctrl-1-inhibitors-ic50-ki.
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