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Chitinase 1 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(2-methylpropyl)piperidin-4-amineIC50232.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(2-methylpropyl)piperidin-4-amineKi312.0 [1]
5-{4-[2-(4-Bromophenoxy)ethyl]piperazin-1-Yl}-4h-1,2,4-Triazol-3-AmineIC506755.0 [1]
1-[1-(5-Amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-3-(4-bromophenyl)ureaIC50100000.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[(4-bromophenyl)methyl]piperidine-4-carboxamideIC50100000.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-bromophenyl)ethyl]-N-ethylpiperidin-4-amineIC50105.0 [1]
N-[[1-(5-Amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]methyl]-4-bromobenzamideIC5023100.0 [1]
N-[1-(5-Amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-1-(4-bromophenyl)methanesulfonamideIC50100000.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-benzyl-N-[2-(4-chlorophenyl)ethyl]piperidin-4-amineIC50163.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-ethylpiperidin-4-amineIC50385.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-cyclopropylphenyl)ethyl]-N-methylpiperidin-4-amineIC50765.0 [1]
N-[1-(5-Amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-2-(4-bromophenyl)acetamideIC50100000.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-bromophenyl)ethyl]-N-(2-methylpropyl)piperidin-4-amineIC50123.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(naphthalen-1-ylmethyl)piperidin-4-amineIC5036.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-methyl-N-(2-phenylethyl)piperidin-4-amineIC50100000.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-bromophenyl)ethyl]-N-methylpiperidin-4-amineIC50175.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-methylpiperidin-4-amineIC50389.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-ethylphenyl)ethyl]-N-methylpiperidin-4-amineIC501011.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-tert-butylphenyl)ethyl]-N-methylpiperidin-4-amineIC504160.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-methyl-N-[2-(4-methylphenyl)ethyl]piperidin-4-amineIC501525.0 [1]
3-[4-[[(4-Bromophenyl)methyl-methylamino]methyl]piperidin-1-yl]-1H-1,2,4-triazol-5-amineIC50100000.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-propan-2-ylpiperidin-4-amineIC50945.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-methyl-N-[2-(4-propan-2-ylphenyl)ethyl]piperidin-4-amineIC501175.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-[(2-chlorophenyl)methyl]piperidin-4-amineIC50149.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(2,4-dichlorophenyl)ethyl]-N-methylpiperidin-4-amineIC502255.0 [1]
N-[1-(5-Amino-1H-1,2,4-triazol-3-yl)piperidin-4-yl]-1-(4-bromophenyl)-N-methylmethanesulfonamideIC50100000.0 [1]
1-(5-Amino-1H-1,2,4-triazol-3-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(cyclohexylmethyl)piperidin-4-amineIC50123.0 [1]
1-[4-(5-Amino-1H-1,2,4-triazol-3-yl)piperazin-1-yl]-2-(4-bromophenoxy)ethanoneIC50100000.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Chitinase 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Nov2024https://www.aatbio.com/data-sets/chitinase-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024November 21). Quest Database™ Chitinase 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/chitinase-1-inhibitors-ic50-ki.
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