| 2-(Pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one | IC50 | 10.0 [1] |
| 8-Chloro-2-[(2s)-Pyrrolidin-2-Yl][1]benzofuro[3,2-D]pyrimidin-4(3h)-One | IC50 | 3.4 [1], 118.0 [2], 140.0 [3] |
| N-[5-(1-Benzyltriazol-4-yl)-1H-indazol-3-yl]benzamide | Ki | 0.4 [1], 0.5 [2], 0.6 [3] |
| 4-(4-Hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(1H)-one | IC50 | 1.4 [1], 3.0 [2] |
| 2-(2-Amino-pyrimidin-4-yl)-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one | IC50 | 7.0 [1] |
| 8-Bromanyl-2-[[(3s)-3-Oxidanylpyrrolidin-1-Yl]methyl]-3h-[1]benzofuro[3,2-D]pyrimidin-4-One | IC50 | 7.7 [1], 1471.0 [2] |
| 2-[[(3S)-3-Aminopyrrolidin-1-yl]methyl]-8-bromo-3H-[1]benzofuro[3,2-d]pyrimidin-4-one | IC50 | 10.0 [1], 625.0 [2] |
| 8-Bromo-2-(pyrrolidin-1-ylmethyl)[1]benzofuro[3,2-d]pyrimidin-4(3H)-one | IC50 | 3.7 [1], 353.0 [2] |
| 8-Bromo-2-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]-3H-[1]benzofuro[3,2-d]pyrimidin-4-one | IC50 | 5.5 [1], 1805.0 [2] |
| 1-(2-Aminopyrimidin-4-yl)indole-6-carbonitrile | IC50 | 75.0 [1], 5000.0 [2] |
| 1-[(8-Bromo-4-oxo-3,4-dihydro[1]benzofuro[3,2-d]pyrimidin-2-yl)methyl]pyrrolidine-3-carboxylic acid | IC50 | 13.0 [1], 40000.0 [2] |
| 8-Bromo-2-[(2S,4R)-4-hydroxypyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one | IC50 | 9.1 [1], 440.0 [2] |
| 2-Azetidin-3-yl-8-bromo[1]benzofuro[3,2-d]pyrimidin-4(3H)-one | IC50 | 7.7 [1], 2536.0 [2] |
| 8-Bromo-2-{[(3S)-3-(methyloxy)pyrrolidin-1-yl]methyl}[1]benzofuro[3,2-d]pyrimidin-4(3H)-one | IC50 | 11.0 [1], 362.0 [2] |
| 8-Bromo-2-piperidin-4-yl[1]benzofuro[3,2-d]pyrimidin-4(3H)-one | IC50 | 6.2 [1], 1434.0 [2] |
| 8-Bromo-2-piperidin-3-yl[1]benzofuro[3,2-d]pyrimidin-4(3H)-one | IC50 | 15.0 [1], 2356.0 [2] |
| 8-Bromo-2-[(2S,4S)-4-fluoropyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one | IC50 | 11.0 [1], 566.0 [2] |
| 2-[(2S,4R)-4-Fluoropyrrolidin-2-yl]-8-(methyloxy)[1]benzofuro[3,2-d]pyrimidin-4(3H)-one | IC50 | 3.9 [1], 292.0 [2] |
| 8-Chloro-2-[(2S,4R)-4-fluoropyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one | IC50 | 4.0 [1], 167.0 [2] |
| 2-(1-Aminoethyl)-8-bromo-3H-[1]benzofuro[3,2-d]pyrimidin-4-one | IC50 | 7.9 [1], 874.0 [2] |
| 8-(Methyloxy)-2-[(2S)-pyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one | IC50 | 6.1 [1], 1374.0 [2] |
| 8-Bromo-2-[(2R)-pyrrolidin-2-yl]-3H-[1]benzofuro[3,2-d]pyrimidin-4-one | IC50 | 70.0 [1], 4592.0 [2] |
| 8-Bromo-2-[(2S)-pyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one | IC50 | 4.8 [1], 75.0 [2] |
| 8-Bromo-2-[(2S,4R)-4-fluoropyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one | IC50 | 3.7 [1], 82.0 [2] |
| 8-Bromo-2-[(2S)-1-methylpyrrolidin-2-yl]-3H-[1]benzofuro[3,2-d]pyrimidin-4-one | IC50 | 7.3 [1], 802.0 [2] |
| 4-(1H-Indol-1-yl)pyrimidin-2-amine | IC50 | 4700.0 [1], 50000.0 [2] |
| 5-(1-Benzyl-5-phenyltriazol-4-yl)-1H-indazol-3-amine | Ki | 1.2 [1], 2.1 [2] |
| 5-[1-Benzyl-5-(4-fluorophenyl)triazol-4-yl]-1H-indazol-3-amine | Ki | 0.8 [1], 2.2 [2] |
| 5-(1-Benzyl-5-methyltriazol-4-yl)-1H-indazol-3-amine | Ki | 17.0 [1], 23.0 [2] |
| N-[5-(1-Benzyltriazol-4-yl)-1H-indazol-3-yl]-3-fluorobenzamide | Ki | 0.5 [1], 1.0 [2] |
| 1-(6-Aminopyrimidin-4-yl)pyrrolo[2,3-b]pyridine-6-carbonitrile | IC50 | 9.0 [1], 1370.0 [2] |
| 1-(2-Aminopyridin-4-yl)indole-6-carbonitrile | IC50 | 9000.0 [1], 50000.0 [2] |
| 2-Pyrimidinamine, 4-(1H-pyrrolo[2,3-b]pyridin-1-yl)- | IC50 | 26700.0 [1], 50000.0 [2] |
| 2-Pyrimidinamine, 4-(6-chloro-1H-pyrrolo[3,2-c]pyridin-1-yl)- | IC50 | 360.0 [1], 50000.0 [2] |
| 4-[3-(2-Chloropyridin-3-yl)pyrrolo[3,2-c]pyridin-1-yl]pyrimidin-2-amine | IC50 | 7.0 [1], 850.0 [2] |
| 4-[6-Chloro-3-(2-chloropyridin-3-yl)pyrrolo[3,2-c]pyridin-1-yl]pyrimidin-2-amine | IC50 | 30.0 [1], 2300.0 [2] |
| N-[5-(1-Benzyl-5-phenyltriazol-4-yl)-1H-indazol-3-yl]benzamide | Ki | 0.8 [1], 0.9 [2] |
| N-[5-(1-Benzyl-5-cyclopropyltriazol-4-yl)-1H-indazol-3-yl]-3-fluorobenzamide | Ki | 0.9 [1], 2.4 [2] |
| Milciclib | IC50 | 10000.0 [1] |
| Pha-793887 | IC50 | 10000.0 [1] |
| CID 59604787 | IC50 | 3500.0 [1] |
| 5-[2,4-Dihydroxy-6-(4-Nitrophenoxy)phenyl]-N-(1-Methylpiperidin-4-Yl)-1,2-Oxazole-3-Carboxamide | IC50 | 10.0 [1] |
| 8-[2-Methoxy-5-(4-methylpiperazin-1-yl)anilino]-1-methyl-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide | IC50 | 10000.0 [1] |
| 5-(2-Aminopyrimidin-4-yl)-2-phenyl-1H-pyrrole-3-carboxamide | IC50 | 22.0 [1] |
| 8-Bromo[1]benzofuro[3,2-d]pyrimidin-4(3H)-one | IC50 | 2000.0 [1] |
| 4-(1H-Indazol-5-yl)-6-phenylpyrimidin-2(1H)-one | IC50 | 10.0 [1] |
| 2-(2-Chloropyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one | IC50 | 147.0 [1] |
| (7S)-2-(2-Aminopyrimidin-4-yl)-7-(2-fluoroethyl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one | IC50 | 2.0 [1] |
| 1H,4H,5H,6H,7H-Pyrrolo[3,2-c]pyridin-4-one | IC50 | 5000.0 [1] |
| 2,2-Dimethyl-7-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)-1-[(1R)-1-phenylethyl]-3H-quinazolin-4-one | IC50 | 1000.0 [1] |
| 3-[(4-Morpholin-4-ylbenzoyl)amino]-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]-1H-thieno[3,2-c]pyrazole-5-carboxamide | IC50 | 1970.0 [1] |
| 2-[[(3R)-3-Aminopyrrolidin-1-yl]methyl]-8-bromo-3H-[1]benzofuro[3,2-d]pyrimidin-4-one | IC50 | 207.0 [1] |
| 5-(1-Benzyl-1h-1,2,3-triazol-4-yl)-1h-indazol-3-amine | Ki | 12.0 [1] |
| 4-[[4-Chloro-6-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-yl]amino]cyclohexan-1-ol | Ki | 0.16 [1] |
| 1-N-[4-Chloro-6-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-yl]-4-N,4-N-dimethylcyclohexane-1,4-diamine | Ki | 0.32 [1] |
| N-[5-(1-Benzyltriazol-4-yl)-1H-indazol-3-yl]-3-chlorobenzamide | Ki | 0.79 [1] |
| 3-Amino-6-{4-Chloro-3-[(2,3-Difluorophenyl)sulfamoyl]phenyl}-N-Methylpyrazine-2-Carboxamide | IC50 | 3600.0 [1] |
| 6-(Cyclohexylamino)-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-1H-pyridin-2-one | Ki | 0.28 [1] |
| 3-Amino-6-[4-chloro-3-[(3-fluoro-2-methylphenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide | IC50 | 3600.0 [1] |
| 4-(6-Chloro-1H-indol-1-yl)pyrimidin-2-amine | IC50 | 66.0 [1] |
| 4-(6-Bromoindol-1-yl)pyrimidin-2-amine | IC50 | 350.0 [1] |
| N-[5-(2,2-Dimethylpropanoyl)-6,6-dimethyl-1,4-dihydropyrrolo[3,4-c]pyrazol-3-yl]-3,5-difluorobenzamide | IC50 | 10000.0 [1] |
| 2-(9H-Purin-6-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one | IC50 | 178.0 [1] |
| 2-(2-Aminopyrimidin-4-yl)-7-methyl-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one | IC50 | 6.0 [1] |
| 2-(2-Aminopyrimidin-4-yl)-7-phenyl-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one | IC50 | 19.0 [1] |
| 2-(2-Aminopyrimidin-4-yl)-6,6-dimethyl-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one | IC50 | 64.0 [1] |
| 2-[2-(Benzylamino)pyrimidin-4-yl]-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one | IC50 | 220.0 [1] |
| 2-[2-(Phenylamino)pyrimidin-4-yl]-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one | IC50 | 7.0 [1] |
| 2-(2-Aminopyrimidin-4-yl)-6-(propan-2-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one | IC50 | 12.0 [1] |
| 2-{2-[(Cyclohexylmethyl)amino]pyrimidin-4-yl}-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one | IC50 | 655.0 [1] |
| 2-(2-Aminopyrimidin-4-yl)-7-(propan-2-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one | IC50 | 4.0 [1] |
| 7-Ethyl-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one | IC50 | 2.0 [1] |
| 8,9,10,11-Tetrahydro-3,8,11-triaza-benzo[a]fluoren-7-one | IC50 | 2.0 [1] |
| N-[4-(4-Oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-2-yl)pyrimidin-2-yl]benzamide | IC50 | 262.0 [1] |
| 2-(2-Aminopyrimidin-4-yl)-6-methyl-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one | IC50 | 26.0 [1] |
| 2-[2-(Propylamino)pyrimidin-4-yl]-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one | IC50 | 259.0 [1] |
| 2-(2-Aminopyrimidin-4-yl)-6-(2-methylpropyl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one | IC50 | 8.0 [1] |
| 2-{2-[(2-Methylpropyl)amino]pyrimidin-4-yl}-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one | IC50 | 636.0 [1] |
| 2-(2-Aminopyrimidin-4-yl)-7,7-diethyl-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one | IC50 | 5.0 [1] |
| 3-Methyl-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one | IC50 | 45.0 [1] |
| 2-{1H-Pyrrolo[2,3-b]pyridin-4-yl}-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one | IC50 | 14.0 [1] |
| 2-(3-Fluoropyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one | IC50 | 9.0 [1] |
| 7,7-Dimethyl-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one | IC50 | 3.0 [1] |
| 7-Methyl-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one | IC50 | 10.0 [1] |
| 7,7-Diethyl-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one | IC50 | 6.0 [1] |
| 2-(4-Piperazin-1-ylphenyl)-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile | IC50 | 60.0 [1] |
| 1-Methyl-2-(4-piperazin-1-ylphenyl)pyrrolo[2,3-b]pyridine-4-carbonitrile | IC50 | 10000.0 [1] |
| 2-Phenyl-5-[(Z)-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-1H-imidazol-4-ol | IC50 | 50.0 [1] |
| 2-(2-Methylmorpholin-4-yl)-5-[(Z)-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-1H-imidazol-4-ol | IC50 | 66.0 [1] |
| 2-(4-Methylpiperidin-1-yl)-5-[(Z)-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-1H-imidazol-4-ol | IC50 | 105.0 [1] |
| 2-(Cyclohexylamino)-5-[(Z)-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-1H-imidazol-4-ol | IC50 | 21.0 [1] |
| 2-(Benzylamino)-5-[(Z)-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-1H-imidazol-4-ol | IC50 | 20.0 [1] |
| 2-(2-Hydroxyethylamino)-5-[(Z)-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-1H-imidazol-4-ol | IC50 | 37.0 [1] |
| 2-(3,3-Dimethylbutylamino)-5-[(Z)-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-1H-imidazol-4-ol | IC50 | 24.0 [1] |
| 2-(Furan-2-ylmethylamino)-5-[(Z)-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-1H-imidazol-4-ol | IC50 | 15.0 [1] |
| 2-(Cyclopropylamino)-5-[(Z)-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-1H-imidazol-4-ol | IC50 | 33.0 [1] |
| 5-[(Z)-Pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-2-(thiophen-2-ylmethylamino)-1H-imidazol-4-ol | IC50 | 18.0 [1] |
| 2-(Oxolan-2-ylmethylamino)-5-[(Z)-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-1H-imidazol-4-ol | IC50 | 21.0 [1] |
| 2-(Pentylamino)-5-[(Z)-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-1H-imidazol-4-ol | IC50 | 35.0 [1] |
| 2-(Heptylamino)-5-[(Z)-pyrrolo[2,3-b]pyridin-3-ylidenemethyl]-1H-imidazol-4-ol | IC50 | 247.0 [1] |