CDGSH iron-sulfur domain-containing protein 1 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	(5Z)-5-(4-Hydroxy-3-methoxybenzylidene)-2-sulfanyl-1,3-thiazol-4(5H)-one	IC50	1730.0 [1]
	(5Z)-5-(4-Hydroxy-3-methoxybenzylidene)-2-sulfanyl-1,3-thiazol-4(5H)-one	Ki	74.0 [1]
	5-(4-Hydroxybenzyl)thiazolidine-2,4-dione	IC50	14000.0 [1]
	5-(4-Hydroxybenzyl)thiazolidine-2,4-dione	Ki	598.0 [1]
	5-[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl-2,4-thiazolidinedione	IC50	7360.0 [1]
	5-[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl-2,4-thiazolidinedione	Ki	315.0 [1]
	5-[(3,5-Dimethylphenyl)methyl]-1,3-thiazolidine-2,4-dione	IC50	13340.0 [1]
	5-[(3,5-Dimethylphenyl)methyl]-1,3-thiazolidine-2,4-dione	Ki	570.0 [1]
	5-[(4-Hydroxy-3,5-dimethylphenyl)methyl]-1,3-thiazolidine-2,4-dione	IC50	9560.0 [1]
	5-[(4-Hydroxy-3,5-dimethylphenyl)methyl]-1,3-thiazolidine-2,4-dione	Ki	409.0 [1]
	5-[(2,2-Difluoro-1,3-benzodioxol-5-yl)methyl]-1,3-thiazolidine-2,4-dione	IC50	5230.0 [1]
	5-[(2,2-Difluoro-1,3-benzodioxol-5-yl)methyl]-1,3-thiazolidine-2,4-dione	Ki	224.0 [1]
	Doxorubicin	IC50	80760.0 [1]
	Doxorubicin	Ki	3451.0 [1]
	Furosemide	IC50	53460.0 [1]
	Furosemide	Ki	2285.0 [1]
	Curcumin	IC50	2360.0 [1]
	Curcumin	Ki	101.0 [1]
	Glyburide	IC50	39100.0 [1]
	Glyburide	Ki	1671.0 [1]
	Resveratrol-3-O-sulfate	IC50	3360.0 [1]
	Resveratrol-3-O-sulfate	Ki	144.0 [1]
	Ursodeoxycholic acid	IC50	26540.0 [1]
	Ursodeoxycholic acid	Ki	1134.0 [1]
	Rosiglitazone	IC50	731.0 [1]
	Rosiglitazone	Ki	31.0 [1]
	Pioglitazone	IC50	8650.0 [1]
	Pioglitazone	Ki	370.0 [1]
	Kaempferol	IC50	3100.0 [1]
	Kaempferol	Ki	132.0 [1]
	Nitrofurantoin	IC50	19100.0 [1]
	Nitrofurantoin	Ki	816.0 [1]
	Gemfibrozil	IC50	170600.0 [1]
	Gemfibrozil	Ki	7291.0 [1]
	(3-Chlorophenyl)hydrazonomalononitrile	IC50	35040.0 [1]
	(3-Chlorophenyl)hydrazonomalononitrile	Ki	1497.0 [1]
	Dantrolene	IC50	48330.0 [1]
	Dantrolene	Ki	2065.0 [1]
	2-Cyano-3-(4-hydroxyphenyl)acrylic acid	IC50	40000.0 [1]
	2-Cyano-3-(4-hydroxyphenyl)acrylic acid	Ki	1700.0 [1]
	4-Amino-1,8-naphthalimide	IC50	264000.0 [1]
	4-Amino-1,8-naphthalimide	Ki	11282.0 [1]
	Triapine	IC50	9078.0 [1]
	Triapine	Ki	388.0 [1]
	Tyrphostin AG 1024	IC50	1800.0 [1]
	Tyrphostin AG 1024	Ki	77.0 [1]
	Tryprostatin A	IC50	3387.0 [1]
	Tryprostatin A	Ki	145.0 [1]
	(5Z)-5-[3-(Trifluoromethyl)benzylidene]-1,3-thiazolidine-2,4-dione	IC50	6940.0 [1]
	(5Z)-5-[3-(Trifluoromethyl)benzylidene]-1,3-thiazolidine-2,4-dione	Ki	297.0 [1]
	4-Hydroxybenzylidenemalononitrile	IC50	1829.0 [1]
	4-Hydroxybenzylidenemalononitrile	Ki	78.0 [1]
	4-Thiazolidinone, 5-[(4-bromophenyl)methylene]-2-thioxo-, (5Z)-	IC50	3180.0 [1]
	4-Thiazolidinone, 5-[(4-bromophenyl)methylene]-2-thioxo-, (5Z)-	Ki	136.0 [1]
	5-(4-Chlorobenzylidene)-3-methyl-2-thioxo-1,3-thiazolidin-4-one	IC50	4980.0 [1]
	5-(4-Chlorobenzylidene)-3-methyl-2-thioxo-1,3-thiazolidin-4-one	Ki	213.0 [1]
	1-Hydroxy-3-(4-phenoxyphenyl)quinoxalin-2(1H)-one 4-oxide	IC50	9657.0 [1]
	1-Hydroxy-3-(4-phenoxyphenyl)quinoxalin-2(1H)-one 4-oxide	Ki	413.0 [1]
	5-(3-Bromobenzylidene)thiazolidine-2,4-dione	IC50	860.0 [1]
	5-(3-Bromobenzylidene)thiazolidine-2,4-dione	Ki	37.0 [1]
	5-(4-(Benzyloxy)-3-methoxybenzylidene)-2-thioxothiazolidin-4-one	IC50	770.1 [1]
	5-(4-(Benzyloxy)-3-methoxybenzylidene)-2-thioxothiazolidin-4-one	Ki	33.0 [1]
	(5Z)-5-[(3-Bromo-4-hydroxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one	IC50	1964.0 [1]
	(5Z)-5-[(3-Bromo-4-hydroxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one	Ki	84.0 [1]
	(5Z)-5-Benzylidene-2-imino-1,3-thiazolidin-4-one	IC50	37320000.0 [1]
	(5Z)-5-Benzylidene-2-imino-1,3-thiazolidin-4-one	Ki	1594000.0 [1]
	(5Z)-5-(3-Bromobenzylidene)-2-thioxo-1,3-thiazolidin-4-one	IC50	1067.0 [1]
	(5Z)-5-(3-Bromobenzylidene)-2-thioxo-1,3-thiazolidin-4-one	Ki	46.0 [1]
	5-[(4-Pyridyl)methylene]thiazolidine-2,4-dione	IC50	22270.0 [1]
	5-[(4-Pyridyl)methylene]thiazolidine-2,4-dione	Ki	952.0 [1]
	(5Z)-5-Benzylidene-3-methyl-2-thioxo-1,3-thiazolidin-4-one	IC50	15120.0 [1]
	(5Z)-5-Benzylidene-3-methyl-2-thioxo-1,3-thiazolidin-4-one	Ki	646.0 [1]
	6-Hydroxy-2-[(2-hydroxyphenyl)methylene]benzo[b]furan-3-one	IC50	148.0 [1]
	6-Hydroxy-2-[(2-hydroxyphenyl)methylene]benzo[b]furan-3-one	Ki	6.0 [1]
	5-[(3,5-Dibromo-4-hydroxyphenyl)methylene]-1,3-thiazolidine-2,4-dione	IC50	3289.0 [1]
	5-[(3,5-Dibromo-4-hydroxyphenyl)methylene]-1,3-thiazolidine-2,4-dione	Ki	141.0 [1]
	(5E)-5-[[3-Chloro-4-[(4-fluorophenyl)methoxy]phenyl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one	IC50	945.4 [1]
	(5E)-5-[[3-Chloro-4-[(4-fluorophenyl)methoxy]phenyl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one	Ki	40.0 [1]
	(2Z)-N-(3-Hydroxyphenyl)-2-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)acetamide	IC50	13650.0 [1]
	(2Z)-N-(3-Hydroxyphenyl)-2-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)acetamide	Ki	583.0 [1]
	(2Z)-2-(4-Oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)-N-phenylacetamide	IC50	11050.0 [1]
	(2Z)-2-(4-Oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)-N-phenylacetamide	Ki	472.0 [1]
	(5Z)-3-Propyl-5-(pyridin-4-ylmethylidene)-1,3-thiazolidine-2,4-dione	IC50	19440.0 [1]
	(5Z)-3-Propyl-5-(pyridin-4-ylmethylidene)-1,3-thiazolidine-2,4-dione	Ki	831.0 [1]
	(5Z)-5-[(2,5-Dibromo-4-chlorophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one	IC50	2930.0 [1]
	(5Z)-5-[(2,5-Dibromo-4-chlorophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one	Ki	125.0 [1]
	(5Z)-5-(Quinoxalin-5-ylmethylidene)-1,3-thiazolidine-2,4-dione	IC50	3260.0 [1]
	(5Z)-5-(Quinoxalin-5-ylmethylidene)-1,3-thiazolidine-2,4-dione	Ki	139.0 [1]
	(5E)-5-[[3-Methoxy-4-[(4-methylphenyl)methoxy]phenyl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one	IC50	518.0 [1]
	(5E)-5-[[3-Methoxy-4-[(4-methylphenyl)methoxy]phenyl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one	Ki	22.0 [1]
	(5Z)-5-(4-Hydroxy-3,5-dimethoxybenzylidene)-2-sulfanyl-1,3-thiazol-4(5H)-one	IC50	4470.0 [1]
	(5Z)-5-(4-Hydroxy-3,5-dimethoxybenzylidene)-2-sulfanyl-1,3-thiazol-4(5H)-one	Ki	191.0 [1]
	(5Z)-2-Sulfanylidene-5-[[3-(trifluoromethyl)phenyl]methylidene]-1,3-thiazolidin-4-one	IC50	3307.0 [1]
	(5Z)-2-Sulfanylidene-5-[[3-(trifluoromethyl)phenyl]methylidene]-1,3-thiazolidin-4-one	Ki	141.0 [1]
	(5Z)-5-[(3-Bromo-4-hydroxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione	IC50	3858.0 [1]
	(5Z)-5-[(3-Bromo-4-hydroxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione	Ki	165.0 [1]
	5-(4-Pyridylmethylene)rhodanine	IC50	5970.0 [1]
	5-(4-Pyridylmethylene)rhodanine	Ki	255.0 [1]
	(Z)-3-(5-Benzylidene-4-oxo-2-thioxothiazolidin-3-yl)propanoic acid	IC50	9630.0 [1]
	(Z)-3-(5-Benzylidene-4-oxo-2-thioxothiazolidin-3-yl)propanoic acid	Ki	412.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ CDGSH iron-sulfur domain-containing protein 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/cdgsh-iron-sulfur-domain-containing-protein-1-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 20). Quest Database™ CDGSH iron-sulfur domain-containing protein 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/cdgsh-iron-sulfur-domain-containing-protein-1-inhibitors-ic50-ki.
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