Cat eye syndrome critical region protein 2 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	(4R)-4-Methyl-6-[1-methyl-3-(1-methylpyrazol-4-yl)indazol-5-yl]-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one	IC50	7700.0 [1]
	Nvs-cecr2-1	IC50	47.0 [1]
	4-Cyano-N-(1,3-diethyl-2-oxoquinolin-6-yl)benzenesulfonamide	IC50	20000.0 [1], 100000.0 [2]
	4-[(2s,4r)-1-Acetyl-4-[(4-Chlorophenyl)amino]-2-Methyl-1,2,3,4-Tetrahydroquinolin-6-Yl]benzoic Acid	IC50	31622.78 [1]
	3-[7-(Difluoromethyl)-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-N-methyl-1-(oxan-4-yl)-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carboxamide	IC50	20000.0 [1]
	N,2-Dimethyl-5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)benzenesulfonamide	IC50	3162.28 [1]
	N-[3-(3-Methyl-4-Oxo-4,5,6,7-Tetrahydro-2h-Isoindol-1-Yl)-4-Phenoxyphenyl]methanesulfonamide	IC50	1000.0 [1]
	N-[5-(3-Methyl-[1,2,4]triazolo[3,4-a]phthalazin-6-yl)-2-morpholin-4-ylphenyl]methanesulfonamide	IC50	158.49 [1]
	1-(3-Phenylazanyl-1,4,6,7-Tetrahydropyrazolo[4,3-C]pyridin-5-Yl)ethanone	IC50	20000.0 [1]
	(4R)-6-[7-(Difluoromethyl)-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-4-methyl-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one	IC50	20000.0 [1]
	N,6-Dimethyl-7-oxo-N-[1-(1-phenylethyl)piperidin-4-yl]-1H-pyrrolo[2,3-c]pyridine-4-carboxamide	IC50	330.0 [1]
	N-Methyl-7-oxo-6-prop-2-enyl-N-[1-(6-pyrazol-1-ylpyrimidin-4-yl)piperidin-4-yl]-1H-pyrrolo[2,3-c]pyridine-4-carboxamide	IC50	59.0 [1]
	N-[1-(6-Methoxypyrimidin-4-yl)piperidin-4-yl]-N-methyl-7-oxo-6-prop-2-enyl-1H-pyrrolo[2,3-c]pyridine-4-carboxamide	IC50	130.0 [1]
	N-Methyl-7-oxo-6-prop-2-enyl-N-(1-pyrimidin-4-ylpiperidin-4-yl)-1H-pyrrolo[2,3-c]pyridine-4-carboxamide	IC50	240.0 [1]
	6-Methyl-N-(1-methylpiperidin-4-yl)-7-oxo-1H-pyrrolo[2,3-c]pyridine-4-carboxamide	IC50	1100.0 [1]
	N,6-Dimethyl-7-oxo-N-(1-propan-2-ylpiperidin-4-yl)-1H-pyrrolo[2,3-c]pyridine-4-carboxamide	IC50	500.0 [1]
	N,6-Dimethyl-N-(1-methylpiperidin-4-yl)-7-oxo-1H-pyrrolo[2,3-c]pyridine-4-carboxamide	IC50	780.0 [1]
	N-Methyl-7-oxo-6-prop-2-enyl-N-[1-[6-(trifluoromethyl)pyrimidin-4-yl]piperidin-4-yl]-1H-pyrrolo[2,3-c]pyridine-4-carboxamide	IC50	200.0 [1]
	1-[3-[7-(Difluoromethyl)-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-1-(oxan-4-yl)-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanone	IC50	14000.0 [1]
	1-[3-[2-Fluoro-4-(1-methylpyrazol-4-yl)anilino]-1-[(3R)-oxolan-3-yl]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]ethanone	IC50	20000.0 [1]
	8-[[(3R,4R)-3-[(1,1-Dioxothian-4-yl)methoxy]-1-methylpiperidin-4-yl]amino]-3-methyl-5-(5-methylpyridin-3-yl)-1H-1,7-naphthyridin-2-one	Ki	794.33 [1]
	N,2-Dimethyl-7-oxo-N-[1-[(1S)-1-phenylethyl]piperidin-4-yl]-6-prop-2-enyl-1H-pyrrolo[2,3-c]pyridine-4-carboxamide	IC50	190.0 [1]
	N-[1-(2,6-Dimethylpyrimidin-4-yl)piperidin-4-yl]-N-methyl-7-oxo-6-prop-2-enyl-1H-pyrrolo[2,3-c]pyridine-4-carboxamide	IC50	93.0 [1]
	N-[1-[6-(3-Methoxyphenyl)pyrimidin-4-yl]piperidin-4-yl]-N-methyl-7-oxo-6-prop-2-enyl-1H-pyrrolo[2,3-c]pyridine-4-carboxamide	IC50	16.0 [1]
	N-[1-(6-Tert-butylpyrimidin-4-yl)piperidin-4-yl]-N-methyl-7-oxo-6-prop-2-enyl-1H-pyrrolo[2,3-c]pyridine-4-carboxamide	IC50	55.0 [1]
	N-Methyl-7-oxo-N-[1-(1-phenylethyl)piperidin-4-yl]-6-prop-2-enyl-1H-pyrrolo[2,3-c]pyridine-4-carboxamide	IC50	500.0 [1]
	N-[1-(6-Cyclopropyl-2-methylpyrimidin-4-yl)piperidin-4-yl]-N-methyl-7-oxo-6-prop-2-enyl-1H-pyrrolo[2,3-c]pyridine-4-carboxamide	IC50	52.0 [1]
	N-[1-(6-Methoxy-2-methylpyrimidin-4-yl)piperidin-4-yl]-N-methyl-7-oxo-6-prop-2-enyl-1H-pyrrolo[2,3-c]pyridine-4-carboxamide	IC50	71.0 [1]
	N-[1-[6-(2-Methoxyphenyl)pyrimidin-4-yl]piperidin-4-yl]-N-methyl-7-oxo-6-prop-2-enyl-1H-pyrrolo[2,3-c]pyridine-4-carboxamide	IC50	45.0 [1]
	N-[1-[6-(2-Fluorophenyl)pyrimidin-4-yl]piperidin-4-yl]-N-methyl-7-oxo-6-prop-2-enyl-1H-pyrrolo[2,3-c]pyridine-4-carboxamide	IC50	44.0 [1]
	N,2-Dimethyl-7-oxo-N-[1-[(1R)-1-phenylethyl]piperidin-4-yl]-6-prop-2-enyl-1H-pyrrolo[2,3-c]pyridine-4-carboxamide	IC50	200.0 [1]
	N-[1-[6-(Furan-2-yl)pyrimidin-4-yl]piperidin-4-yl]-N-methyl-7-oxo-6-prop-2-enyl-1H-pyrrolo[2,3-c]pyridine-4-carboxamide	IC50	45.0 [1]
	N-[1-(6-Cyclopropylpyrimidin-4-yl)piperidin-4-yl]-N-methyl-7-oxo-6-prop-2-enyl-1H-pyrrolo[2,3-c]pyridine-4-carboxamide	IC50	83.0 [1]
	N-Methyl-N-[1-[6-(2-methylphenyl)pyrimidin-4-yl]piperidin-4-yl]-7-oxo-6-prop-2-enyl-1H-pyrrolo[2,3-c]pyridine-4-carboxamide	IC50	46.0 [1]
	N,N,2-Trimethyl-5-(3-methyl-[1,2,4]triazolo[3,4-a]phthalazin-6-yl)benzenesulfonamide	IC50	251.19 [1]
	N-[2-Methyl-5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)phenyl]methanesulfonamide	IC50	501.19 [1]
	N-[2-Methyl-5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)phenyl]propanamide	IC50	5011.87 [1]
	2-Chloro-N-[5-(3-methyl-[1,2,4]triazolo[3,4-a]phthalazin-6-yl)-2-morpholin-4-ylphenyl]benzenesulfonamide	IC50	25118.86 [1]
	4-Methoxy-N-[2-(4-methylpiperazin-1-yl)-5-(3-methyl-[1,2,4]triazolo[3,4-a]phthalazin-6-yl)phenyl]benzenesulfonamide	IC50	1000.0 [1]
	4-Chloro-N-[5-(3-methyl-[1,2,4]triazolo[3,4-a]phthalazin-6-yl)-2-morpholin-4-ylphenyl]benzenesulfonamide	IC50	19952.62 [1]
	3-[2-(2,4-Difluorophenoxy)-5-methylsulfonylphenyl]-1-methyl-6H-pyrrolo[2,3-c]pyridin-7-one	IC50	1000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 41 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Cat eye syndrome critical region protein 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/cat-eye-syndrome-critical-region-protein-2-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 20). Quest Database™ Cat eye syndrome critical region protein 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/cat-eye-syndrome-critical-region-protein-2-inhibitors-ic50-ki.
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