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Casein kinase I gamma 2 Inhibitors (IC50, Ki)

Structure
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▼
Compound Name
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Standard Type
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Standard Values (in nM)
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▼
2-[2-[(3,4-Difluorophenoxy)methyl]-5-methoxypyridin-4-yl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-oneIC505.0 [1], 200.0 [2], 254.0 [3]
2-[2-[2-(4-Fluorophenyl)ethyl]-5-methoxypyridin-4-yl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-oneIC5026.0 [1], 840.0 [2], 1300.0 [3]
2-[5-Methoxy-2-(Quinolin-3-Yl)pyrimidin-4-Yl]-1,5,6,7-Tetrahydro-4h-Pyrrolo[3,2-C]pyridin-4-OneIC508.0 [1], 348.0 [2], 3333.0 [3]
2-[2-[(4,5-Difluoro-2-methylphenoxy)methyl]-5-methoxypyridin-4-yl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-oneIC504.0 [1], 44.0 [2], 87.0 [3]
2-[2-[(4-Fluoro-2-methylphenoxy)methyl]-5-methoxypyridin-4-yl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-oneIC503.0 [1], 537.0 [2]
2-[2-[(4-Fluorophenoxy)methyl]-5-methoxypyridin-4-yl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-oneIC505.0 [1], 584.0 [2]
2-[2-[(2,4-Difluorophenoxy)methyl]-5-methoxypyridin-4-yl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-oneIC503.0 [1], 394.0 [2]
7-Chloro-3-oxo-8-(1,3-thiazol-5-ylmethylamino)-11,16-dioxa-2,4,19,21-tetrazatricyclo[15.3.1.05,10]henicosa-1(20),5,7,9,17(21),18-hexaene-18-carbonitrileKi7166.0 [1]
1-({4-[(3,4-Dichlorophenyl)methoxy]phenyl}methyl)azetidine-3-carboxylic acidIC5010000.0 [1]
6-(2,4-Difluorophenyl)sulfonyl-2-(1H-indol-5-ylamino)-8-methylpyrido[2,3-d]pyrimidin-7-oneIC5010000.0 [1]
2-[(4-{[3-(Trifluoromethyl)pyridin-2-Yl]oxy}phenyl)amino]-1h-Benzimidazole-6-CarbonitrileIC506560.0 [1]
2-(4-Tert-butylanilino)-1,3-benzoxazole-6-carbonitrileIC5014900.0 [1]
2-(4-Tert-butylanilino)-1,3-benzothiazole-6-carbonitrileIC503830.0 [1]
2-[(4-Tert-Butylphenyl)amino]-1h-Benzimidazole-6-CarbonitrileIC501510.0 [1]
2-(4-Phenylanilino)-3H-benzimidazole-5-carbonitrileIC504890.0 [1]
N-(4-Tert-butylphenyl)-6-nitro-1H-benzimidazol-2-amineIC502340.0 [1]
2-(4-Tert-butylanilino)-6-methyl-1H-benzimidazole-5-carbonitrileIC5013000.0 [1]
2-[4-(2-Fluoropyridin-3-yl)anilino]-3H-benzimidazole-5-carbonitrileIC501170.0 [1]
2-(4-Methylanilino)-3H-benzimidazole-5-carbonitrileIC504540.0 [1]
2-[4-(2-Hydroxypropan-2-yl)anilino]-3H-benzimidazole-5-carbonitrileIC50700.0 [1]
2-[4-(1-Methylpyrazol-4-yl)anilino]-3H-benzimidazole-5-carbonitrileIC501450.0 [1]
2-(4-Tert-butyl-2-fluoroanilino)-3H-benzimidazole-5-carbonitrileIC5010100.0 [1]
2-(4-Tert-butylanilino)imidazo[1,2-a]pyridine-6-carbonitrileIC509100.0 [1]
2-[2-[(E)-2-(4-Fluorophenyl)ethenyl]-5-methoxypyrimidin-4-yl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-oneIC5050.0 [1]
2-[2-[2-(4-Fluorophenyl)ethyl]-5-methoxypyrimidin-4-yl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-oneIC5017.0 [1]
2-[2-[(4-Fluorophenyl)methoxy]-5-methoxypyrimidin-4-yl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-oneIC5080.0 [1]
2-(2-Anilino-5-methoxypyrimidin-4-yl)-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-oneIC508.0 [1]
2-(5-Methoxy-2-phenoxypyrimidin-4-yl)-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-oneIC50853.0 [1]
2-[2-(Benzylamino)-5-methoxypyrimidin-4-yl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-oneIC5033.0 [1]
2-[2-[(4-Fluorophenoxy)methyl]-5-methoxypyrimidin-4-yl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-oneIC5024.0 [1]
Items per page: 1 - 10 of 30
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References

This online tool may be cited as follows

MLA

"Quest Database™ Casein kinase I gamma 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Nov. 2024, https://www.aatbio.com/data-sets/casein-kinase-i-gamma-2-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, November 21). Quest Database™ Casein kinase I gamma 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/casein-kinase-i-gamma-2-inhibitors-ic50-ki.
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