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Carboxypeptidase B Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
2-Benzylsuccinic acidKi10000.0 [1]
GemsaKi1100.0 [1]
(2s)-5-Amino-2-[(1-Propyl-1h-Imidazol-4-Yl)methyl]pentanoic AcidKi206.0 [1]
2-(4-Benzyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-ylthio)-1-(4-fluorophenyl)ethanoneKi74500.0 [1]
N1-Benzyl-N4-((tetrahydrofuran-2-yl)methyl)-N4-(thiophen-2-ylmethyl)benzene-1,4-disulfonamideKi23000.0 [1]
[5-(2-Fluoro-phenyl)-[1,3,4]oxadiazol-2-ylsulfanyl]-acetic acid benzyl esterKi67200.0 [1]
2-[4-Furan-2-ylmethyl-5-(4-hydroxy-phenyl)-4H-[1,2,4]triazol-3-ylsulfanyl]-1-thiophen-2-yl-ethanoneKi9100.0 [1]
N-(3-Methoxy-benzyl)-3-methyl-N-pyridin-3-ylmethyl-4-tetrazol-1-yl-benzenesulfonamideKi23900.0 [1]
N-(2-(2-(2-(4-Methoxyphenyl)-2-oxoethyl)-2H-tetrazol-5-yl)phenyl)cyclopropanecarboxamideKi292000.0 [1]
2-(4-Benzoylpiperidine-1-carbonyl)benzoic acidKi20700.0 [1]
3-Pyridinepropanoic acid, 6-amino-alpha-1H-imidazol-5-yl-IC5070.0 [1]
3-(6-Aminopyridin-3-yl)-2-[1-(3-methylbutyl)imidazol-4-yl]propanoic acidIC504.0 [1]
(2S)-2-(2-Aminoethoxy)-3-(1-phenylimidazol-4-yl)propanoic AcidKi27.0 [1]
(2S)-2-(2-Aminoethylamino)-3-(1-propylimidazol-4-yl)propanoic acidKi1160.0 [1]
6-Amino-2-(1H-imidazol-4-yl)-hexanoic acidIC503700.0 [1]
(S)-2-((R)-1-Aminopropan-2-yloxy)-3-(1-phenyl-1H-imidazol-4-yl)propanoic acidKi240.0 [1]
(2S)-2-[(2R)-1-Aminopropan-2-yl]oxy-3-(1-pyridin-2-ylimidazol-4-yl)propanoic acidKi265.0 [1]
2-(4-Benzyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-ylthio)acetamideKi11600.0 [1]
N-[[Di(propan-2-yl)amino]-[(2S,3S)-3-(4-methoxyphenyl)-2-trimethylsilyloxiran-2-yl]phosphinothioyl]-N-propan-2-ylpropan-2-amineKi3000.0 [1]
N-[[Di(propan-2-yl)amino]-[(2S,3S)-3-(4-nitrophenyl)-2-trimethylsilyloxiran-2-yl]phosphinothioyl]-N-propan-2-ylpropan-2-amineKi1060.0 [1]
N-[[Di(propan-2-yl)amino]-[(2S,3S)-3-(4-methylphenyl)-2-trimethylsilyloxiran-2-yl]phosphinothioyl]-N-propan-2-ylpropan-2-amineKi9100.0 [1]
2-(5-((4-Chlorophenoxy)methyl)-1,3,4-oxadiazol-2-ylthio)-1-p-tolylethanoneKi11700.0 [1]
(1S,2R)-Methyl 2-((1S,2R)-2-(benzyloxycarbonylamino)cyclobutanecarboxamido)cyclobutanecarboxylateKi70000.0 [1]
Methyl 5-((1S,2R)-2-(benzyloxycarbonylamino)cyclobutanecarboxamido)pentanoateKi410000.0 [1]
Isopropyl 2-(4-benzyl-5-(2-methoxyphenyl)-4H-1,2,4-triazol-3-ylthio)acetateKi7400.0 [1]
4-(5-(2-Chlorobenzylthio)-1,3,4-oxadiazol-2-yl)-N-(thiophen-2-ylmethyl)benzenesulfonamideKi40000.0 [1]
N-[[Di(propan-2-yl)amino]-[(2S,3S)-3-[4-(trifluoromethyl)phenyl]-2-trimethylsilyloxiran-2-yl]phosphinothioyl]-N-propan-2-ylpropan-2-amineKi3900.0 [1]
N-(2-Chlorobenzyl)-N-(furan-2-ylmethyl)-3-methyl-4-(1H-tetrazol-1-yl)benzenesulfonamideKi16600.0 [1]
(2S)-6-Amino-2-[[(2R)-3-cyclohexyl-1-oxo-1-[(4,7,7-trimethyl-2-bicyclo[2.2.1]heptanyl)amino]propan-2-yl]carbamoylamino]hexanoic acidIC501.0 [1]
Methyl 2-[[4-benzyl-5-(2-hydroxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetateKi4900.0 [1]
2-(Pyridin-4-ylmethylamino)-1-(4-tosylpiperazin-1-yl)ethanoneKi364000.0 [1]
3-Methyl-N-(2-methylphenethyl)-4-(1H-tetrazol-1-yl)benzenesulfonamideKi25900.0 [1]
2-(2-Methoxyphenyl)-N-[5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl]-N-propylacetamideKi25100.0 [1]
N-(3-Chlorophenyl)-4-((5-(3-methoxybenzylthio)-1,3,4-oxadiazol-2-yl)methyl)thiazol-2-amineKi1200.0 [1]
2-[2-(Methylamino)ethoxy]-3-(1-propylimidazol-4-yl)propanoic acidKi10000.0 [1]
Methyl 3-((1R,2S)-2-(benzyloxycarbonylamino)cyclobutanecarboxamido)propanoateKi400000.0 [1]
2-(2-Aminoethoxy)-3-[1-(2-methylphenyl)imidazol-4-yl]propanoic acidKi2720.0 [1]
2-(3-Carbamimidamidopropylidene)butanedioic acidIC50360.0 [1]
N-Benzyl-N-(4-phenylthiazol-2-yl)cyclopropanecarboxamideKi4500.0 [1]
Ethyl 2-(4-ethyl-5-((4-ethylphenoxy)methyl)-4H-1,2,4-triazol-3-ylthio)-3-methylbutanoateKi10800.0 [1]
6-Amino-2-(1H-imidazol-4-yl)-5,5-dimethyl-hexanoic acidIC50600.0 [1]
6-Amino-2-(1H-imidazol-4-yl)-5-methyl-hexanoic acidIC501500.0 [1]
3-[(1R,3S)-3-Aminocyclopentyl]-2-[1-(3,3-dimethylbutyl)imidazol-4-yl]propanoic acidIC501.0 [1]
3-[(1R,3S)-3-Aminocyclopentyl]-2-(1-ethylimidazol-4-yl)propanoic acidIC50150.0 [1]
3-(6-Aminopyridin-3-yl)-2-[1-(4-methylpentyl)imidazol-4-yl]propanoic acidIC504.0 [1]
3-(6-Amino-5-methylpyridin-3-yl)-2-[1-(4-methylpentyl)imidazol-4-yl]propanoic acidIC501.0 [1]
3-(6-Amino-5-methylpyridin-3-yl)-2-[1-(3-methylbutyl)imidazol-4-yl]propanoic acidIC501.0 [1]
N-[[Di(propan-2-yl)amino]-[(2S,3S)-3-pyridin-2-yl-2-trimethylsilyloxiran-2-yl]phosphinothioyl]-N-propan-2-ylpropan-2-amineKi15100.0 [1]
N-[[Di(propan-2-yl)amino]-[(2S,3S)-3-pyridin-3-yl-2-trimethylsilyloxiran-2-yl]phosphinothioyl]-N-propan-2-ylpropan-2-amineKi16700.0 [1]
N-[[Di(propan-2-yl)amino]-[(2S,3S)-3-pyridin-4-yl-2-trimethylsilyloxiran-2-yl]phosphinothioyl]-N-propan-2-ylpropan-2-amineKi9700.0 [1]
N-[[Di(propan-2-yl)amino]-[(2S,3R)-3-thiophen-2-yl-2-trimethylsilyloxiran-2-yl]phosphinothioyl]-N-propan-2-ylpropan-2-amineKi7200.0 [1]
N-[[Di(propan-2-yl)amino]-[(2S,3S)-3-thiophen-3-yl-2-trimethylsilyloxiran-2-yl]phosphinothioyl]-N-propan-2-ylpropan-2-amineKi9200.0 [1]
N-[[Di(propan-2-yl)amino]-[(2S,3S)-3-(furan-2-yl)-2-trimethylsilyloxiran-2-yl]phosphinothioyl]-N-propan-2-ylpropan-2-amineKi23500.0 [1]
N-[[Di(propan-2-yl)amino]-[(2S,3S)-3-(furan-3-yl)-2-trimethylsilyloxiran-2-yl]phosphinothioyl]-N-propan-2-ylpropan-2-amineKi16700.0 [1]
Methyl 2-((1R,2S)-2-(benzyloxycarbonylamino)cyclobutanecarboxamido)acetateKi500000.0 [1]
3-((1R,2S)-2-(Benzyloxycarbonylamino)cyclobutanecarboxamido)propanoic acidKi43000.0 [1]
(1R,2S)-Methyl 2-((1R,2S)-2-(benzyloxycarbonylamino)cyclobutanecarboxamido)cyclobutanecarboxylateKi275000.0 [1]
3-(5-(2-(2-Fluorophenyl)-2-oxoethylthio)-1H-tetrazol-1-yl)benzoic acidKi33600.0 [1]
2-[[4-Benzyl-5-[2-(3-methylphenyl)ethyl]-1,2,4-triazol-3-yl]sulfanyl]acetic acidKi196000.0 [1]
2-[[4-[(2-Methoxyphenyl)methyl]-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methylpiperidin-1-yl)ethanoneKi20800.0 [1]
(S)-2-(2-Aminoethoxy)-3-(1-propyl-1H-imidazol-4-yl)propanoic acidKi238.0 [1]
(S)-2-(2-Aminoethoxy)-3-(1-(4-tert-butylphenyl)-1H-imidazol-4-yl)propanoic acidKi49.0 [1]
(S)-2-(2-Aminoethoxy)-3-(1-(2-cyclohexylethyl)-1H-imidazol-4-yl)propanoic acidKi27.0 [1]
2-(2-Aminoethoxy)-3-(1-butylimidazol-4-yl)propanoic acidKi360.0 [1]
(R)-2-(2-Aminoethoxy)-3-(1-propyl-1H-imidazol-4-yl)propanoic acidKi10000.0 [1]
2-(6,9-Dimethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-1-(4-fluorophenyl)ethanoneKi15000.0 [1]
(2S)-6-Amino-2-[[(2R)-1-(3-methylbutylamino)-1-oxo-6-(phenylmethoxycarbonylamino)hexan-2-yl]carbamoylamino]hexanoic acidIC50190.0 [1]
1-(4-Chlorophenyl)-2-(5-(2-hydroxyphenyl)-1,3,4-oxadiazol-2-ylthio)ethanoneKi7500.0 [1]
1-(2-Fluorophenyl)-2-(5-o-tolyl-1,3,4-oxadiazol-2-ylthio)ethanoneKi14700.0 [1]
3-(6-Amino-5-methyl-pyridin-3-yl)-2-(1H-imidazol-4-yl)-propionic acidIC5020.0 [1]
6-Amino-2-[1-(3-methyl-butyl)-1H-imidazol-4-yl]-hexanoic acidIC50160.0 [1]
3-(6-Aminopyridin-3-yl)-2-(1-piperidin-4-ylimidazol-4-yl)propanoic acidIC501130.0 [1]
3-(6-Aminopyridin-3-yl)-2-[1-(4,4-dimethylcyclohexyl)imidazol-4-yl]propanoic acidIC503.0 [1]
3-(6-Aminopyridin-3-yl)-2-[1-[(5-chloro-1-benzothiophen-3-yl)methyl]imidazol-4-yl]propanoic acidIC501110.0 [1]
3-(6-Aminopyridin-3-yl)-2-[1-[[1-(2,2-diphenylacetyl)piperidin-3-yl]methyl]imidazol-4-yl]propanoic acidIC5011.0 [1]
3-(6-Aminopyridin-3-yl)-2-[1-[2-[1-(2,2-diphenylacetyl)piperidin-4-yl]ethyl]imidazol-4-yl]propanoic acidIC5012.0 [1]
3-(6-Aminopyridin-3-yl)-2-[1-[4-(phenylcarbamoylamino)phenyl]imidazol-4-yl]propanoic acidIC5015.0 [1]
3-(6-Aminopyridin-3-yl)-2-(1-prop-2-ynyl-1H-imidazol-4-yl)propionic acidIC50870.0 [1]
3-(6-Aminopyridin-3-yl)-2-[1-[2-(benzhydrylamino)-2-oxoethyl]imidazol-4-yl]propanoic acidIC5023.0 [1]
3-(6-Aminopyridin-3-yl)-2-[1-[[4-(trifluoromethoxy)phenyl]methyl]imidazol-4-yl]propanoic acidIC5010510.0 [1]
3-(6-Aminopyridin-3-yl)-2-[1-(2-oxo-1-phenylpyrrolidin-3-yl)imidazol-4-yl]propanoic acidIC50439.0 [1]
3-(6-Aminopyridin-3-yl)-2-[1-[[3-(4-fluorophenoxy)phenyl]methyl]imidazol-4-yl]propanoic acidIC501440.0 [1]
3-(6-Aminopyridin-3-yl)-2-[1-[2-[1-(3-phenylpropanoyl)piperidin-4-yl]ethyl]imidazol-4-yl]propanoic acidIC5021.0 [1]
3-(6-Aminopyridin-3-yl)-2-[1-[2-[1-(3-phenylpropanoyl)piperidin-3-yl]ethyl]imidazol-4-yl]propanoic acidIC5038.0 [1]
3-(6-Aminopyridin-3-yl)-2-(1-cyclohexylimidazol-4-yl)propanoic acidIC5030.0 [1]
3-(6-Aminopyridin-3-yl)-2-[1-[4-(propylcarbamoylamino)phenyl]imidazol-4-yl]propanoic acidIC5049.0 [1]
3-(6-Aminopyridin-3-yl)-2-[1-[(1-benzoylpiperidin-2-yl)methyl]imidazol-4-yl]propanoic acidIC5012.0 [1]
3-(6-Aminopyridin-3-yl)-2-(1-cyclopentyl-1H-imidazol-4-yl)propionic acidIC5016.0 [1]
Items per page: 1 - 10 of 88
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References

This online tool may be cited as follows

MLA

"Quest Database™ Carboxypeptidase B Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/carboxypeptidase-b-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Carboxypeptidase B Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/carboxypeptidase-b-inhibitors-ic50-ki.
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