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Carbonic anhydrase XIII Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
AcetazolamideKi17.0 [1]
PhenolKi697000.0 [1]
CelecoxibKi98.0 [1]
SulfanilamideKi32.0 [1], 35.0 [2]
CoumarinKi200000.0 [1], 1000000.0 [2]
2-HydroxyquinolineKi65.0 [1]
Pyrithione zincKi4150.0 [1]
Thiobenzoic acidKi1310.0 [1]
ResveratrolKi4090.0 [1]
DobutamineKi9530.0 [1]
BortezomibKi8450.0 [1]
TopiramateKi47.0 [1]
1,3-Benzenediol, 5-[(1Z)-2-(4-hydroxyphenyl)ethenyl]-Ki8250.0 [1]
SilymarinKi4820.0 [1]
Ellagic acidKi4240.0 [1]
PepcidKi171.5 [1]
DorzolamideKi18.0 [1]
Phenylboronic acidKi50000.0 [1]
ValdecoxibKi425.0 [1]
ScopoletinKi17800.0 [1]
MethazolamideKi19.0 [1]
BrinzolamideKi11.0 [1]
CoumaphosKi4230.0 [1]
DichlorphenamideKi23.0 [1]
(1E,4Z,6E)-5-Hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-oneKi6850.0 [1]
LacosamideKi1210.0 [1]
ScopolinKi8430.0 [1]
L-EpicatechinKi10510.0 [1]
1,2-Benzoxazol-3-ylmethanesulfonimidic acidKi430.0 [1]
FraxetinKi9730.0 [1]
5-Amino-1,3,4-thiadiazole-2-sulfonamideKi79.0 [1]
XanthyletinKi8360.0 [1]
FraxinKi9800.0 [1]
2-Hydroxycinnamic acidKi1000000.0 [1]
IsoscopoletinKi5270.0 [1]
XanthoxyletinKi3150.0 [1]
GeiparvarinKi9620.0 [1]
DimethylfraxetinKi4240.0 [1]
N-(4-Sulfamoylphenyl)-2-(thiophen-2-yl)acetamideKi125.0 [1]
5-{[(4-Amino-3-Chloro-5-Fluorophenyl)sulfonyl]amino}-1,3,4-Thiadiazole-2-SulfonamideKi0.7 [1]
AvicennolKi29300.0 [1]
(S)-6-(1-Hydroxy-3-methylbutyl)-7-methoxy-2H-chromen-2-oneKi7860.0 [1]
Calanolide BKi21000.0 [1]
FraxidinKi95700.0 [1]
4-[2-(2,4,6-Trimethylpyridin-1-ium-1-yl)ethyl]benzenesulfonamide;perchlorateKi21.0 [1]
7-Hydroxy-8-methoxycoumarinKi7260.0 [1]
N-({[4-(Aminosulfonyl)phenyl]amino}carbonyl)-4-methylbenzenesulfonamideKi11.0 [1]
Psammaplin CKi10630.0 [1]
N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)adamantane-1-carboxamideKi118.0 [1]
AlloxanthoxyletinKi5910.0 [1]
5,7,8-TrimethoxycoumarinKi3320.0 [1]
2-(7-Methoxy-2-oxochromen-8-yl)-3-methylbut-2-enalKi8890.0 [1]
N-(2-Fluoro-4-Sulfamoylphenyl)-2-(Thiophen-2-Yl)acetamideKi437.0 [1]
(E)-4-(4-Hydroxyphenyl)-1-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]but-3-en-2-oneKi8600.0 [1]
2-(1-Adamantyl)-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamideKi147.0 [1]
[(2R,3R,4R,5S,6S)-3,4,5-Triacetyloxy-6-[(E)-4-(4-hydroxyphenyl)-2-oxobut-3-enyl]oxan-2-yl]methyl acetateKi4900.0 [1]
7-Hydroxy-6,13,14-trimethoxy-2,9-dioxatetracyclo[6.6.2.04,16.011,15]hexadeca-1(15),4,6,8(16),11,13-hexaene-3,10-dioneKi5970.0 [1]
4-(4,6-Bis-methylamino-[1,3,5]triazin-2-ylamino)-benzenesulfonamideKi921.0 [1]
2-[[4-Chloro-6-[2-(4-sulfamoylphenyl)ethylamino]-1,3,5-triazin-2-yl]amino]acetic acidKi68.0 [1]
2-[[4-Chloro-6-[(4-sulfamoylphenyl)methylamino]-1,3,5-triazin-2-yl]amino]acetic acidKi62.0 [1]
4-[3',6'-Bis(diethylamino)-3-oxospiro[isoindole-1,9'-xanthene]-2-yl]benzenesulfonamideKi280.0 [1]
3-[3',6'-Bis(diethylamino)-3-oxospiro[isoindole-1,9'-xanthene]-2-yl]benzenesulfonamideKi236.0 [1]
4-[[3',6'-Bis(diethylamino)-3-oxospiro[isoindole-1,9'-xanthene]-2-yl]methyl]benzenesulfonamideKi515.0 [1]
4-[2-[3',6'-Bis(diethylamino)-3-oxospiro[isoindole-1,9'-xanthene]-2-yl]ethyl]benzenesulfonamideKi463.0 [1]
[(2R,3S,4R,5S,6S)-3,4,5-Triacetyloxy-6-[(E)-4-(3-hydroxyphenyl)-2-oxobut-3-enyl]oxan-2-yl]methyl acetateKi7200.0 [1]
[(2R,3S,4R,5S,6S)-3,4,5-Triacetyloxy-6-[(E)-4-(4-hydroxyphenyl)-2-oxobut-3-enyl]oxan-2-yl]methyl acetateKi6700.0 [1]
(E)-4-(3-Hydroxyphenyl)-1-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]but-3-en-2-oneKi8800.0 [1]
(E)-4-(3-Hydroxyphenyl)-1-[(2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]but-3-en-2-oneKi8600.0 [1]
[(2R,3R,4R,5S,6S)-3,4,5-Triacetyloxy-6-[(E)-4-(3-hydroxyphenyl)-2-oxobut-3-enyl]oxan-2-yl]methyl acetateKi5100.0 [1]
(E)-4-(4-Hydroxyphenyl)-1-[(2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]but-3-en-2-oneKi100000.0 [1]
5-({[(4-Methylphenyl)sulfonyl]carbamoyl}amino)pyridine-2-SulfonamideKi38.0 [1]
7-Hydroxy-12-(4-hydroxy-3-methoxyphenyl)-8,16,17,18-tetramethoxy-4-oxa-1-azapentacyclo[11.8.0.02,11.05,10.014,19]henicosa-2(11),5,7,9,12,14,16,18,20-nonaen-3-oneKi3700.0 [1]
4-[2-[4-(3-Phenylureido)butyrylamino]ethyl]benzenesulfonamideKi240.0 [1]
4-[(4-Nitrophenyl)carbamoylamino]-N-[2-(4-sulfamoylphenyl)ethyl]butanamideKi240.0 [1]
4-(Phenylcarbamoylamino)-N-[(4-sulfamoylphenyl)methyl]butanamideKi240.0 [1]
4-(Benzylcarbamoylamino)-N-[(4-sulfamoylphenyl)methyl]butanamideKi240.0 [1]
4-(Benzylcarbamoylamino)-N-[2-(4-sulfamoylphenyl)ethyl]butanamideKi240.0 [1]
4-(2-Phenylethylcarbamoylamino)-N-[(4-sulfamoylphenyl)methyl]butanamideKi240.0 [1]
[2-(7-Methoxy-2-oxochromen-8-yl)-3-methylbut-3-enyl] pyridine-3-carboxylateKi4060.0 [1]
RacemosinKi100000.0 [1]
5-Aminopyridine-2-sulfonamideKi155.0 [1]
DihydrogeiparvarimKi27400.0 [1]
AvicenninKi45000.0 [1]
7-[(E)-7-Hydroxy-3,7-dimethyl-6-oxooct-2-enoxy]chromen-2-oneKi6100.0 [1]
Lamellarin EKi4630.0 [1]
4-(7-Methylpyrazolo[3',4':4,5]thiopyrano[2,3-B]pyridin-1(4h)-Yl)benzenesulfonamideKi4630.0 [1]
2-Amino-6-chloro-3-(4-methoxyphenyl)-4H-chromen-4-oneKi7850.0 [1]
4,6-Dimethyl-2H-pyran-2-one oximeKi59.0 [1]
(NZ)-N-chromen-2-ylidenehydroxylamineKi94.0 [1]
4-(8-Thia-3,4,10-triazatricyclo[7.4.0.02,6]trideca-1(9),2(6),4,10,12-pentaen-3-yl)benzenesulfonamideKi4300.0 [1]
4-[7-(Trifluoromethyl)-4H-thiochromeno[4,3-c]pyrazol-1-yl]benzenesulfonamideKi714.0 [1]
4-(7-Methoxy-4H-thiochromeno[4,3-c]pyrazol-1-yl)benzenesulfonamideKi938.0 [1]
4-(7-Chloro-4H-thiochromeno[4,3-c]pyrazol-1-yl)benzenesulfonamideKi2810.0 [1]
Sodium;[8-hydroxy-12-(3-hydroxy-4-methoxyphenyl)-7,16-dimethoxy-3-oxo-4-oxa-1-azapentacyclo[11.8.0.02,11.05,10.014,19]henicosa-2(11),5,7,9,12,14,16,18-octaen-17-yl] sulfateKi4240.0 [1]
7-Hydroxy-6-[(E)-4-hydroxy-3-methylbut-2-enyl]chromen-2-oneKi6350.0 [1]
4-(4,6-Difluoro-1,3,5-triazine-2-ylamino)benzenesulfonamideKi1030.0 [1]
4-[2-[(4,6-Difluoro-1,3,5-triazin-2-yl)amino]ethyl]benzenesulfonamideKi470.0 [1]
4-[[4-Fluoro-6-(2-hydroxyethylamino)-1,3,5-triazin-2-yl]amino]benzenesulfonamideKi10000.0 [1]
4-[[4-Fluoro-6-(methylamino)-1,3,5-triazin-2-yl]amino]benzenesulfonamideKi735.0 [1]
Methyl 2-[[4-fluoro-6-[2-(4-sulfamoylphenyl)ethylamino]-1,3,5-triazin-2-yl]amino]acetateKi602.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Carbonic anhydrase XIII Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/carbonic-anhydrase-xiii-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Carbonic anhydrase XIII Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/carbonic-anhydrase-xiii-inhibitors-ic50-ki.
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