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CaM kinase II delta Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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3-[1-(3-Aminopropyl)indol-3-yl]-4-phenylpyrrole-2,5-dioneIC50230.0 [1], 350.0 [2], 1350.0 [3]
3-[1-(3-Aminopropyl)-1H-indol-3-YL]-4-(1H-indol-3-YL)-1H-pyrrole-2,5-dioneIC50380.0 [1]
3-[1-(3-Aminopropyl)indol-3-yl]-4-(1-benzothiophen-3-yl)pyrrole-2,5-dioneIC5039.0 [1], 360.0 [2]
3-[1-(3-Aminopropyl)-1H-indol-3-YL]-4-(1-methyl-1H-indol-3-YL)-1H-pyrrole-2,5-dioneIC50310.0 [1]
3-[1-(3-Aminopropyl)indol-3-yl]-4-(5-bromo-1H-indol-3-yl)pyrrole-2,5-dioneIC5034.0 [1]
3-[1-(3-Aminopropyl)indol-3-yl]-4-(3-bromophenyl)pyrrole-2,5-dioneIC50180.0 [1]
Tert-butyl N-[3-[3-(2,5-dioxo-4-phenylpyrrol-3-yl)indol-1-yl]propyl]carbamateIC5020000.0 [1]
Tert-butyl N-[3-[3-[4-(1H-indol-3-yl)-2,5-dioxopyrrol-3-yl]indol-1-yl]propyl]carbamateIC503810.0 [1]
Tert-butyl N-[3-[3-[4-(5-bromo-1H-indol-3-yl)-2,5-dioxopyrrol-3-yl]indol-1-yl]propyl]carbamateIC507540.0 [1]
3-[1-(3-Aminopropyl)indol-3-yl]-4-(2-methyl-1H-indol-3-yl)pyrrole-2,5-dioneIC50750.0 [1]
3-[1-(3-Aminopropyl)indol-3-yl]-4-indol-1-ylpyrrole-2,5-dioneIC504560.0 [1]
N-(3-Chlorophenyl)-4-(3-piperazin-1-ylphenyl)pyrimidin-2-amineIC509.0 [1], 320.0 [2]
N'-[3-[2-(3-Chloroanilino)pyrimidin-4-yl]phenyl]ethane-1,2-diamineIC5012.0 [1], 110.0 [2]
Bisindolylmaleimide IVIC501190.0 [1]
KN-62IC50380.0 [1]
DoramapimodIC5030000.0 [1]
Bisindolylmaleimide IIIC501890.0 [1]
CID 73442760IC50810000.0 [1]
1-({4-[(3,4-Dichlorophenyl)methoxy]phenyl}methyl)azetidine-3-carboxylic acidIC5010000.0 [1]
3-(1-Methyl-1H-indol-3-yl)-4-(1-piperidin-4-yl-1H-indol-3-yl)-pyrrole-2,5-dioneIC50640.0 [1]
2-(1H-Indole-3-yl)-3-phenylmaleimideIC5020000.0 [1]
3-[3-(2-Aminoethyl)indol-1-yl]-4-(5-chloro-1H-indol-3-yl)pyrrole-2,5-dioneIC5010.0 [1]
5-(2-Amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-tert-butylpyridine-3-sulfonamideIC5010000.0 [1]
(Arylindolyl)maleimide deriv. 23IC5020000.0 [1]
1-[5-Tert-butyl-3-[4-[2-(dimethylamino)ethyl]-5-oxo-1,4-diazepane-1-carbonyl]thiophen-2-yl]-3-(2,3-dichlorophenyl)ureaIC5012000.0 [1]
6-(2,4-Difluorophenyl)sulfonyl-2-(1H-indol-5-ylamino)-8-methylpyrido[2,3-d]pyrimidin-7-oneIC5010000.0 [1]
1-[3,4-Dichlorophenyl]-3-[4-[[[1-ethyl-3-pyrrolidinyl]methyl]amino]-6-methyl-2-pyrimidinyl]guanidineIC502460.0 [1]
3-[1-(1-Benzylpiperidin-4-yl)indol-3-yl]-4-(1-methylindol-3-yl)pyrrole-2,5-dioneIC501870.0 [1]
2-[5-Amino-6-[1-methyl-7-[(3S)-3-methylpiperazin-1-yl]benzimidazol-2-yl]pyrazin-2-yl]-N,N-dimethylpyridine-4-carboxamideIC50690.0 [1]
3-[1-(3-Aminopropyl)indazol-3-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dioneIC50380.0 [1]
Bisindolyl deriv. 23IC501450.0 [1]
Bisindolylmaleimide VIIIC502020.0 [1]
2-N-(5,6-Dichloro-1H-benzimidazol-2-yl)-4-N-(1-ethylpiperidin-3-yl)-6-methylpyrimidine-2,4-diamineIC501880.0 [1]
3-[1-(3-Aminopropyl)indol-3-yl]-4-(3-phenylphenyl)pyrrole-2,5-dioneIC501320.0 [1]
3-[1-(3-Aminopropyl)indol-3-yl]-4-(furan-2-yl)pyrrole-2,5-dioneIC501490.0 [1]
3-[1-(3-Aminopropyl)indol-3-yl]-4-(3-methylphenyl)pyrrole-2,5-dioneIC50280.0 [1]
Tert-butyl N-[3-[3-(2,5-dioxo-4-thiophen-2-ylpyrrol-3-yl)indol-1-yl]propyl]carbamateIC5020000.0 [1]
3-[1-(3-Aminopropyl)indol-3-yl]-4-thiophen-2-ylpyrrole-2,5-dioneIC501190.0 [1]
3-[1-(3-Aminopropyl)indol-3-yl]-4-pyridin-4-ylpyrrole-2,5-dioneIC501600.0 [1]
3-[1-(3-Aminopropyl)indol-3-yl]-4-pyridin-3-ylpyrrole-2,5-dioneIC50540.0 [1]
3-[1-(3-Aminopropyl)indol-3-yl]-4-pyridin-2-ylpyrrole-2,5-dioneIC501580.0 [1]
3-[1-(3-Aminopropyl)indol-3-yl]-4-quinolin-2-ylpyrrole-2,5-dioneIC5020000.0 [1]
3-[1-(3-Aminopropyl)indol-3-yl]-4-quinolin-4-ylpyrrole-2,5-dioneIC50630.0 [1]
3-[1-(3-Aminopropyl)indol-3-yl]-4-naphthalen-2-ylpyrrole-2,5-dioneIC50500.0 [1]
3-[1-(3-Aminopropyl)indol-3-yl]-4-naphthalen-1-ylpyrrole-2,5-dioneIC50290.0 [1]
3-[1-(3-Aminopropyl)indol-3-yl]-4-(5-bromo-1H-indol-3-yl)-1-methylpyrrole-2,5-dioneIC5020000.0 [1]
Tert-butyl N-[3-[3-[4-(1-benzothiophen-3-yl)-2,5-dioxopyrrol-3-yl]indol-1-yl]propyl]carbamateIC5020000.0 [1]
3-[1-(3-Aminopropyl)indol-3-yl]-1-methyl-4-phenylpyrrole-2,5-dioneIC5015020.0 [1]
3-[1-(3-Aminopropyl)indol-3-yl]-4-(1-benzothiophen-3-yl)-1-methylpyrrole-2,5-dioneIC502320.0 [1]
Tert-butyl N-[3-[3-[4-(2-methyl-1H-indol-3-yl)-2,5-dioxopyrrol-3-yl]indol-1-yl]propyl]carbamateIC507610.0 [1]
3-[1-(3-Aminopropyl)indol-3-yl]-4-(3-phenoxyphenyl)pyrrole-2,5-dioneIC501680.0 [1]
3-(1-Methylindol-3-yl)-4-(1-piperidin-3-ylindol-3-yl)pyrrole-2,5-dioneIC50300.0 [1]
N,N-Dimethyl-3-[4-[3-[2-(methylamino)ethyl]indol-1-yl]-2,5-dioxopyrrol-3-yl]-1H-indole-5-carboxamideIC5011850.0 [1]
N-Methyl-3-[4-[3-[2-(methylamino)ethyl]indol-1-yl]-2,5-dioxopyrrol-3-yl]-1H-indole-5-carboxamideIC50280.0 [1]
3-[4-[3-[2-(Methylamino)ethyl]indol-1-yl]-2,5-dioxopyrrol-3-yl]-1H-indole-5-carboxamideIC50190.0 [1]
3-[4-[3-[2-(Methylamino)ethyl]indol-1-yl]-2,5-dioxopyrrol-3-yl]-1H-indole-5-carboxylic acidIC50380.0 [1]
3-[3-(2-Aminoethyl)indol-1-yl]-4-(5-methoxy-1H-indol-3-yl)pyrrole-2,5-dioneIC50170.0 [1]
Methyl 3-[4-[3-[2-(methylamino)ethyl]indol-1-yl]-2,5-dioxopyrrol-3-yl]-1H-indole-5-carboxylateIC5021.0 [1]
3-(5-Ethyl-1H-indol-3-yl)-4-[3-[2-(methylamino)ethyl]indol-1-yl]pyrrole-2,5-dioneIC50110.0 [1]
3-[4-[3-(2-Aminoethyl)indol-1-yl]-2,5-dioxopyrrol-3-yl]-1H-indole-5-carbonitrileIC5046.0 [1]
3-(3-Bromophenyl)-4-(1H-indol-3-yl)pyrrole-2,5-dioneIC503530.0 [1]
3-[3-(2-Aminoethyl)indol-1-yl]-4-[5-(trifluoromethyl)-1H-indol-3-yl]pyrrole-2,5-dioneIC5032.0 [1]
3-[3-(2-Aminoethyl)indol-1-yl]-4-(5-fluoro-1H-indol-3-yl)pyrrole-2,5-dioneIC5038.0 [1]
3-(5-Chloro-1H-indol-3-yl)-4-[3-[2-(methylamino)ethyl]indol-1-yl]pyrrole-2,5-dioneIC5013.0 [1]
3-(1H-Indol-3-yl)-4-(3-piperidin-4-ylindol-1-yl)pyrrole-2,5-dioneIC50680.0 [1]
3-[3-[(Dimethylamino)methyl]indol-1-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dioneIC502410.0 [1]
3-(1H-Indol-3-yl)-4-[3-[2-(methylamino)ethyl]indol-1-yl]pyrrole-2,5-dioneIC50150.0 [1]
3-[3-[2-(Dimethylamino)ethyl]indol-1-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dioneIC50560.0 [1]
3-[3-(2-Aminoethyl)indol-1-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dioneIC50110.0 [1]
3-[3-(3-Hydroxypropyl)indol-1-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dioneIC506000.0 [1]
3-[3-[3-(Dimethylamino)propyl]indol-1-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dioneIC50740.0 [1]
3-(5-Bromo-1H-indol-3-yl)-4-(1-methylindol-3-yl)pyrrole-2,5-dioneIC50870.0 [1]
3-[3-(3-Aminopropyl)indol-1-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dioneIC50190.0 [1]
3-[1-(3-Aminopropyl)-2-methylindol-3-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dioneIC50740.0 [1]
3-[1-(3-Amino-2-hydroxypropyl)indol-3-yl]-4-phenylpyrrole-2,5-dioneIC50450.0 [1]
N-(3-Chlorophenyl)-4-(3-piperidin-1-ylphenyl)pyrimidin-2-amineIC50930.0 [1]
N-(3-Chlorophenyl)-4-(3-morpholin-4-ylphenyl)pyrimidin-2-amineIC50240.0 [1]
4-(3-Aminophenyl)-N-(3-chlorophenyl)pyrimidin-2-amineIC50660.0 [1]
N-Phenyl-4-[4-(2H-tetrazol-5-yl)phenyl]pyrimidin-2-amineIC50770.0 [1]
4-(2-Anilinopyrimidin-4-yl)-N-hydroxybenzamideIC50290.0 [1]
4-(2-Anilinopyrimidin-4-yl)-N-methylbenzamideIC5020000.0 [1]
Methyl 4-(2-anilinopyrimidin-4-yl)benzoateIC5020000.0 [1]
2-[4-(2-Anilinopyrimidin-4-yl)phenyl]acetic acidIC5020000.0 [1]
4-[2-(3-Chloroanilino)pyrimidin-4-yl]benzoic acidIC5042.0 [1]
4-(2-Anilinopyrimidin-4-yl)benzoic acidIC5064.0 [1]
4-[2-(Pyridin-4-ylamino)pyrimidin-4-yl]benzoic acidIC50390.0 [1]
4-[2-[(2-Aminopyridin-4-yl)amino]pyrimidin-4-yl]benzoic acidIC5066.0 [1]
2-N-[(1S)-1-Phenylethyl]-4-N-[4-[4-(2H-tetrazol-5-yl)phenyl]pyrimidin-2-yl]pyridine-2,4-diamineIC502260.0 [1]
N-Hydroxy-4-[2-[[2-[[(1S)-1-phenylethyl]amino]pyridin-4-yl]amino]pyrimidin-4-yl]benzamideIC50170.0 [1]
N-Methyl-4-[2-[[2-[[(1S)-1-phenylethyl]amino]pyridin-4-yl]amino]pyrimidin-4-yl]benzamideIC50720.0 [1]
2-[4-[2-[[2-[[(1S)-1-Phenylethyl]amino]pyridin-4-yl]amino]pyrimidin-4-yl]phenyl]acetic acidIC503420.0 [1]
4-N-[4-[4-(Dimethylamino)phenyl]pyrimidin-2-yl]-2-N-[(1S)-1-phenylethyl]pyridine-2,4-diamineIC502220.0 [1]
3-[2-[[2-[[(1S)-1-Phenylethyl]amino]pyridin-4-yl]amino]pyrimidin-4-yl]benzoic acidIC5012990.0 [1]
4-[2-[[2-[[(1S)-1-Phenylethyl]amino]pyridin-4-yl]amino]pyrimidin-4-yl]benzoic acidIC50210.0 [1]
Methyl 4-[2-[[2-[[(1S)-1-phenylethyl]amino]pyridin-4-yl]amino]pyrimidin-4-yl]benzoateIC501690.0 [1]
4-N-[4-(4-Chlorophenyl)pyrimidin-2-yl]-2-N-[(1S)-1-phenylethyl]pyridine-2,4-diamineIC502870.0 [1]
4-N-[4-(3-Methylphenyl)pyrimidin-2-yl]-2-N-[(1S)-1-phenylethyl]pyridine-2,4-diamineIC50920.0 [1]
2-N-[(1S)-1-Phenylethyl]-4-N-[4-(3-phenylphenyl)pyrimidin-2-yl]pyridine-2,4-diamineIC503140.0 [1]
4-N-[4-(3-Fluorophenyl)pyrimidin-2-yl]-2-N-[(1S)-1-phenylethyl]pyridine-2,4-diamineIC501280.0 [1]
N-[(1R)-1-Cyanoethyl]-3-[5-[4-[(oxan-4-ylamino)methyl]phenyl]-1,2-oxazol-3-yl]benzamideIC507900.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ CaM kinase II delta Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Nov. 2024, https://www.aatbio.com/data-sets/cam-kinase-ii-delta-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, November 21). Quest Database™ CaM kinase II delta Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/cam-kinase-ii-delta-inhibitors-ic50-ki.
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