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c-Jun N-terminal kinase 3 Inhibitors (IC50, Ki)

Structure
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▼
Compound Name
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Standard Type
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▼
Standard Values (in nM)
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▼
JNK Inhibitor VIC5070.0 [1], 120.0 [2]
Jnk-IN-8IC500.98 [1], 1.0 [2], 338.0 [3], 486.0 [4]
1,9-PyrazoloanthroneIC5090.0 [1], 190.0 [2]
4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazoleIC50290.0 [1], 790.0 [2]
4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazoleKi90.0 [1]
DoramapimodIC501400.0 [1], 10000.0 [2]
N-(4-(2-(Phenylamino)pyridin-4-yl)pyridin-2-yl)-tetrahydrofuran-3-carboxamideIC506.31 [1], 7.0 [2]
4-[3-(4-Fluorophenyl)-5-isopropylisoxazol-4-yl]pyridineIC50540.0 [1]
Jnk-IN-7IC500.7 [1], 130.0 [2], 244.0 [3]
N-[[5-[4-(Benzotriazol-1-yl)piperidin-1-yl]sulfonylthiophen-2-yl]methyl]-4-chlorobenzamideIC50150.0 [1]
4-[[(E)-4-(Dimethylamino)but-2-enoyl]amino]-N-[3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamideIC50704.0 [1], 709.0 [2], 2400.0 [3]
3-[[(E)-4-(Dimethylamino)but-2-enoyl]amino]-N-[4-[[4-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)pyrimidin-2-yl]amino]phenyl]benzamideIC500.5 [1], 9.0 [2], 48.0 [3]
JNK Inhibitor VIIIKi52.0 [1]
TanzisertibIC506.0 [1]
N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)benzamideIC501500.0 [1], 1584.89 [2]
N-Cyclohexyl-4-[5-(3,4-dichlorophenyl)-2-piperidin-4-yl-3-propylimidazol-4-yl]pyrimidin-2-amineIC501.6 [1], 2.0 [2]
9-(4-Hydroxyphenyl)-2,7-phenanthrolineIC50590.0 [1]
4-[5-(4-Fluorophenyl)-3-isopropylisoxazol-4-yl]pyridineIC503500.0 [1]
3-{5-[(2-Fluorophenyl)amino]-1h-Indazol-1-Yl}-N-(3,4,5-Trimethoxyphenyl)benzamideIC509.0 [1]
CID 25222038IC50148.0 [1]
Methyl 6-bromo-2-[(4-methylsulfonylphenyl)methyl]-1-oxo-4-phenylisoquinoline-3-carboxylateIC5030.0 [1]
5-Methyl-N-(4-(2-(phenylamino)pyridin-4-yl)pyridin-2-yl)pyrazine-2-carboxamideIC5033.0 [1]
N-(2-Methoxyphenyl)-3-phenyl-1H-indazol-6-amineIC50202.0 [1]
N,3-Diphenyl-1H-indazol-6-amineIC5048.0 [1]
4-(6-(2-Chlorophenylamino)-1H-indazol-3-yl)-N-(2-(dimethylamino)ethyl)benzamideIC501.9 [1]
N-(4-Fluorophenyl)-4-(2-(4-fluorophenylamino)pyridin-4-yl)pyridin-2-amineIC5017.0 [1]
N-(2-Methoxyphenyl)-4-(2-(2-methoxyphenylamino)pyridin-4-yl)pyridin-2-amineIC50528.0 [1]
[(5S)-2-(4-Fluorophenyl)-3-[2-(propylamino)pyrimidin-4-yl]-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-5-yl]methanolIC502.5 [1]
Methyl 3-[2-(2-thienyl)acetamido]thiophene-2-carboxylateIC502200.0 [1]
N-[3-[4-(4-Fluorophenyl)-5-pyridin-4-ylimidazol-1-yl]propyl]benzamideIC50130.0 [1]
3-[6-(2-Chloro-phenylamino)-1H-indazol-3-yl]-N-piperidin-4-yl-benzamideIC501.26 [1], 1.4 [2]
4-[(4-Phenylpyrimidin-2-yl)amino]benzamideIC50491.0 [1]
4-[(4-Phenylpyrimidin-2-yl)amino]benzamideKi130.0 [1]
N-(4-(2-(4-(1H-1,2,3-Triazol-1-yl)phenylamino)pyrimidin-4-yl)-phenyl)methanesulfonamideIC504.0 [1]
N-[4-Bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl]-2-(2-oxo-3,4-dihydroquinolin-1-yl)acetamideIC5028.0 [1]
2-[5-(2-Chloroanilino)indazol-1-yl]-N-(2-morpholin-4-ylethyl)pyridine-4-carboxamideIC50120.0 [1]
N-{2'-[(4-Fluorophenyl)amino]-4,4'-Bipyridin-2-Yl}-4-MethoxycyclohexanecarboxamideIC5015.0 [1], 235.0 [2]
3-[4-[(2-Chlorophenyl)carbamoylamino]pyrazol-1-yl]-N-(1-propan-2-ylpyrazol-4-yl)benzamideIC50114.0 [1], 3250.0 [2]
1-Ethyl-3-[4-[(7-oxo-8-propan-2-ylpyrido[2,3-d]pyrimidin-2-yl)amino]cyclohexyl]ureaIC5037.0 [1], 57.0 [2]
3-[4-[(2-Chlorophenyl)carbamoylamino]pyrazol-1-yl]-N-(2,6-dimethylpyridin-4-yl)benzamideIC50130.0 [1], 2331.0 [2]
2-Methyl-N-[4-[(7-oxo-8-propan-2-ylpyrido[2,3-d]pyrimidin-2-yl)amino]cyclohexyl]propanamideIC5031.0 [1], 321.0 [2]
3-[4-[(2-Chlorophenyl)carbamoylamino]pyrazol-1-yl]-N-(1-piperidin-4-ylpyrazol-4-yl)benzamideIC5023.0 [1], 1436.0 [2]
3-[4-[(2-Chlorophenyl)carbamoylamino]pyrazol-1-yl]-N-[(6-methylpyridin-3-yl)methyl]benzamideIC50311.0 [1], 905.0 [2]
4-N-[4-[2-[4-(1H-Benzimidazol-2-ylamino)naphthalen-1-yl]oxypyridin-3-yl]pyrimidin-2-yl]cyclohexane-1,4-diamineIC501.9 [1], 7.5 [2]
7-Chloro-1-(3,4-dichlorophenyl)-6-methoxy-3,4-dihydroisoquinolineIC5050.12 [1], 316.23 [2]
7-Chloro-1-(3-chlorophenyl)-6-methoxy-3,4-dihydroisoquinolineIC50125.89 [1], 251.19 [2]
2-[[5-Chloro-2-(2-methoxy-4-morpholin-4-ylanilino)pyridin-4-yl]amino]-N-methylbenzamideIC5083.0 [1]
3-[4-[(2-Chlorophenyl)carbamoylamino]pyrazol-1-yl]-N-(piperidin-4-ylmethyl)benzamideIC50206.0 [1], 1895.0 [2]
3-(4-{[(2-Chlorophenyl)carbamoyl]amino}-1h-Pyrazol-1-Yl)-N-(2-Methylpyridin-4-Yl)benzamideIC5098.0 [1], 866.0 [2]
2-[[5-Chloro-2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]benzamideIC500.28 [1], 0.3 [2]
2-[[5-Chloro-2-(2-methoxy-4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]benzamideIC500.78 [1], 0.8 [2]
2-[[5-Chloro-2-[4-(2-oxopyrrolidin-1-yl)anilino]pyrimidin-4-yl]amino]benzamideIC500.16 [1]
2-(Benzo[d]thiazol-2-yl)-2-(2-(methylamino)pyrimidin-4-yl)acetonitrileIC50950.0 [1]
SotrastaurinIC5010000.0 [1]
NeflamapimodIC505000.0 [1]
Cfms Receptor Tyrosine Kinase InhibitorIC5016000.0 [1]
2-({5-Chloro-2-[(2-Methoxy-4-Morpholin-4-Ylphenyl)amino]pyrimidin-4-Yl}amino)-N-MethylbenzamideIC5012.0 [1]
RepSoxIC5016000.0 [1]
Aminofurazanyl-azabenzimidazole 6nIC5010000.0 [1]
2-(2-(2-Methoxy-4-morpholinophenylamino)-5-(trifluoromethyl)pyridin-4-ylamino)-N-methylbenzamideIC50160.0 [1]
CID 25182616IC502000.0 [1]
TCS JNK 5aIC50199.53 [1]
IKK-3 InhibitorIC5015848.93 [1]
4-Methyl-3-(2-((2-morpholinoethyl)amino)quinazolin-6-yl)-N-(3-(trifluoromethyl)phenyl)benzamideIC50145.0 [1]
CID 11634725Ki1400.0 [1]
CID 59604787IC5010000.0 [1]
6,7-Dimethoxy-1-phenyl-3,4-dihydroisoquinolineIC5015848.93 [1]
CID 72547959IC50364.0 [1]
1-(4-Chlorophenyl)-6,7-dimethoxy-3,4-dihydroisoquinolineIC5015848.93 [1]
N-[4-[3-(6-Methylpyridin-3-yl)-1,2,4-triazol-1-yl]phenyl]-4-(3-morpholin-4-ylphenyl)pyrimidin-2-amineIC50159.0 [1]
N-(3-Cyanophenyl)-2'-Methyl-5'-(5-Methyl-1,3,4-Oxadiazol-2-Yl)-4-BiphenylcarboxamideIC5016000.0 [1]
4-[[9-[(3R)-3-Oxolanyl]-8-(2,4,6-trifluoroanilino)-2-purinyl]amino]-1-cyclohexanolIC5032.0 [1]
8-N-(2,2-Dimethylpropyl)-2-N-[2-ethoxy-4-(4-methyl-1,2,4-triazol-3-yl)phenyl]-6-methylpyrido[3,4-d]pyrimidine-2,8-diamineIC50242.0 [1]
2-(4-Pyridinyl)-N-[3-(trifluoromethyl)phenyl]-1,3-thiazole-4-carboxamideKi13000.0 [1]
N~3~-Cyclopropyl-N~4~'-(Cyclopropylmethyl)-6-Methylbiphenyl-3,4'-DicarboxamideIC5016000.0 [1]
1-[3-(Trifluoromethyl)benzyl]-1H-indole-2,3-dione 3-oximeKi5200.0 [1]
(3Z)-3-(Hydroxyimino)-1-[(4-methylphenyl)methyl]-2,3-dihydro-1H-indol-2-oneKi9900.0 [1]
1-(3-Chlorobenzyl)-1H-indole-2,3-dione 3-oximeKi5000.0 [1]
1-(4-Chlorobenzyl)-1H-indole-2,3-dione 3-oximeKi6700.0 [1]
CID 44814409IC5010000.0 [1]
N-(3-Cyano-4,5,6,7-Tetrahydro-1-Benzothien-2-Yl)-2-FluorobenzamideIC50398.11 [1]
N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-(morpholin-4-yl)acetamideIC5015848.93 [1]
Methyl 3-(2-(4-methoxyphenyl)acetamido)thiophene-2-carboxylateIC501000.0 [1]
1-Benzyl-3-(hydroxyimino)indoline-2-oneKi10000.0 [1]
5-Bromo-N-[3-chloro-2-(4-ethyl-1-piperazinyl)phenyl]-2-furamideIC501100.0 [1]
4-Amino-5-cyano-6-ethoxy-N-[(4-methylsulfonylphenyl)methyl]pyridine-2-carboxamideIC5060.0 [1]
7-[[(16E)-14,19-Dioxa-5,7,27-triazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(24),2(27),3,5,8(26),9,11,16,21(25),22-decaen-11-yl]oxy]-N-hydroxyheptanamideIC501000.0 [1]
N-[3-Cyano-7-(cyclopropanecarbonyl)-5,6-dihydro-4H-thieno[2,3-b]pyridin-2-yl]naphthalene-1-carboxamideIC50251.19 [1]
N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-4-fluoronaphthalene-1-carboxamideIC501000.0 [1]
N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-4-fluorobenzamideIC503162.28 [1]
N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-phenylacetamideIC5015848.93 [1]
2-(2-(Methylsulfinyl)benzylthio)-5-(4-fluorophenyl)-4-(pyridin-4-yl)pyrimidineIC5028500.0 [1]
N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)acetamideKi520.0 [1]
Lck InhibitorIC507300.0 [1]
4-Amino-5-chloro-6-ethoxy-pyridine-2-carboxylic acid 4-methanesulfonyl-benzylamideIC50120.0 [1]
[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[4,5-c]pyridin-7-yl]-[(3S)-3-aminopyrrolidin-1-yl]methanoneIC5010000.0 [1]
N-(Cyclopropylmethyl)-2'-Methyl-5'-(5-Methyl-1,3,4-Oxadiazol-2-Yl)biphenyl-4-CarboxamideIC5016000.0 [1]
1-(2,6-Dichlorophenyl)-5-(2,4-difluorophenyl)-7-(4-piperidinyl)-1,2,3,4-tetrahydroquinazoline-2-oneIC5010000.0 [1]
4-[6-(Cyclopropylmethylamino)imidazo[1,2-b]pyridazin-3-yl]-N-[2-(dimethylamino)ethyl]benzamideIC50100000.0 [1]
2-Fluoro-6-[[2-[2-methoxy-4-(4-propan-2-ylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]benzamideIC50100.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ c-Jun N-terminal kinase 3 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/c-jun-n-terminal-kinase-3-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 22). Quest Database™ c-Jun N-terminal kinase 3 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/c-jun-n-terminal-kinase-3-inhibitors-ic50-ki.
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