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C-C chemokine receptor type 2 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
TAK-779 cationIC5012.0 [1]
CID 10436045Ki50.0 [1], 50.12 [2]
Teijin-lead_cmp_5IC5016.0 [1], 54.0 [2], 70.0 [3], 300.0 [4]
6-Methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[1H-3,1-benzoxazine-4,4'-piperidine]-2-oneIC5089.0 [1]
Bms ccr2 22IC501.0 [1], 18.0 [2]
2-Amino-N-[2-[[4-[(4-methylsulfanylbenzoyl)amino]piperidin-3-yl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamideIC5075.0 [1], 109.0 [2]
[(1S,3R)-3-[[(3S,4S)-3-Methoxyoxan-4-yl]amino]-1-propan-2-ylcyclopentyl]-[4-[4-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methanoneIC503.2 [1]
CCR2 antagonist 4IC5024.0 [1], 180.0 [2], 300.0 [3], 980.0 [4]
Incb8761(PF-4136309)IC500.5 [1], 3.3 [2], 3.9 [3], 5.2 [4], 19.0 [5]
(E)-3-(3,4-Dichlorophenyl)-N-[4-[[4-(5-hydroxy-1H-indol-3-yl)piperidin-1-yl]methyl]cyclohexyl]prop-2-enamideKi79.43 [1], 126.0 [2], 316.0 [3], 316.23 [4]
N-[2-[[(1S,2R,4R)-2-(Benzenesulfonylmethyl)-4-[methyl(propan-2-yl)amino]cyclohexyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamideIC500.8 [1], 1.3 [2]
[(1S,3R)-3-[[(3S,4S)-3-Methoxyoxan-4-yl]amino]-1-propan-2-ylcyclopentyl]-[4-[4-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]methanoneIC508.5 [1], 8.9 [2], 11.0 [3], 17.0 [4], 18.2 [5]
[(1S,3R)-3-[[(3S,4S)-3-Methoxyoxan-4-yl]amino]-1-propan-2-ylcyclopentyl]-[4-[6-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methanoneIC506.2 [1], 18.8 [2], 27.5 [3], 79.0 [4]
2-Amino-N-[2-[[4-[(4-methylsulfanylphenyl)methylamino]piperidin-3-yl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamideIC506.1 [1], 6.3 [2], 7.0 [3], 285.0 [4], 749.3 [5]
2-[1-[(E)-3-(3,5-Difluorophenyl)prop-2-enoyl]piperidin-4-yl]-2-[[4-(1H-indol-3-yl)cyclohexyl]amino]acetamideIC504.0 [1], 6.0 [2], 187.0 [3], 740.0 [4]
(S)-N-(3,5-Bis(trifluoromethyl)benzyl)-2-(4-fluorophenyl)-2-(2-(piperidin-1-yl)ethylamino)acetamideIC50173.78 [1], 175.0 [2], 180.0 [3]
(2S)-N-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-2-[2-(dimethylamino)ethylamino]-2-(4-fluorophenyl)acetamideIC50720.0 [1], 770.0 [2], 776.25 [3]
(E)-3-(3,4-Dichlorophenyl)-N-[4-[[4-(1H-indol-3-yl)piperidin-1-yl]methyl]cyclohexyl]prop-2-enamideKi125.89 [1], 126.0 [2], 631.0 [3], 645.65 [4]
N-[2-[[(2S,3S)-1-[(2,4-Dimethylphenyl)methylamino]-3-hydroxyhexan-2-yl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamideIC505.0 [1], 240.0 [2]
N-[2-[[(2S,3S)-1-[(2,4-Dimethylphenyl)methylamino]-3-hydroxyhexan-2-yl]amino]-2-oxoethyl]-2-(propan-2-ylcarbamoylamino)-5-(trifluoromethyl)benzamideIC504.7 [1], 9.9 [2]
(2S)-N-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-2-(2-piperidin-1-ylethylamino)-2-thiophen-3-ylacetamideIC5030.0 [1], 38.9 [2], 39.0 [3], 50.0 [4]
(1S,3R)-N-[[3-Fluoro-5-(trifluoromethyl)phenyl]methyl]-3-[(1S,3'R)-3'-methylspiro[indene-1,4'-piperidine]-1'-yl]-1-propan-2-ylcyclopentane-1-carboxamideIC500.15 [1], 0.71 [2], 3.09 [3], 3.1 [4]
(1R,3R)-N-[[3-Fluoro-5-(trifluoromethyl)phenyl]methyl]-1-(2-methylpropyl)-3-[(1S,3'R)-3'-methylspiro[indene-1,4'-piperidine]-1'-yl]cyclopentane-1-carboxamideIC500.32 [1], 2.04 [2], 3.89 [3], 3.9 [4]
(1S,3R)-1-Cyclopropyl-N-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]-3-[(1S,3'R)-3'-methylspiro[indene-1,4'-piperidine]-1'-yl]cyclopentane-1-carboxamideIC500.23 [1], 0.63 [2], 1.9 [3], 1.91 [4]
N-[(3S)-1-[(1S,2R,4R)-2-(Benzenesulfonylmethyl)-4-[methyl(propan-2-yl)amino]cyclohexyl]-2-oxopyrrolidin-3-yl]-3-(trifluoromethyl)benzamideIC500.5 [1], 1.0 [2]
3,4-Dichloro-N-[5-chloro-2-(triazol-1-ylmethyl)phenyl]benzenesulfonamideKi10.0 [1], 79.43 [2], 100.0 [3]
2-Amino-N-[2-[[(3R)-1-[(4-chlorophenyl)methyl]pyrrolidin-3-yl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamideIC503.6 [1], 23.1 [2], 26.0 [3], 45.0 [4]
N-[2-[[2-[[(1S,3S,4R)-4-Amino-3-(benzenesulfonylmethyl)cyclohexyl]amino]-2-oxoethyl]carbamoyl]-4-(trifluoromethyl)phenyl]azetidine-1-carboxamideIC501.4 [1], 6.6 [2], 8.0 [3], 10.0 [4]
2-[[4-(1H-Indol-3-yl)cyclohexyl]amino]-2-[1-[(E)-3-(3,4,5-trifluorophenyl)prop-2-enoyl]piperidin-4-yl]acetamideIC5016.0 [1], 25.0 [2], 406.0 [3], 880.0 [4]
CID 57400418IC502.6 [1], 3.7 [2], 4.7 [3], 6.0 [4]
(3S)-1-[(1S,2R,4R)-4-[Methyl(propan-2-yl)amino]-2-propylcyclohexyl]-3-[[6-(trifluoromethyl)quinazolin-4-yl]amino]pyrrolidin-2-oneIC500.24 [1], 0.7 [2], 4.7 [3]
(2S)-N-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-2-phenyl-2-(2-piperidin-1-ylethylamino)acetamideIC50218.78 [1], 219.0 [2], 220.0 [3]
2-[4-(1H-Indol-3-yl)piperidin-1-yl]-2-[1-[(E)-3-(3,4,5-trifluorophenyl)prop-2-enoyl]piperidin-4-yl]acetic acidIC505.0 [1]
2-[4-(1H-Indol-3-yl)piperidin-1-yl]-2-[1-[(E)-3-(3,4,5-trifluorophenyl)prop-2-enoyl]piperidin-4-yl]acetamideIC501800.0 [1]
(2S)-N-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-2-phenyl-2-[2-(4-phenylpiperidin-1-yl)ethylamino]acetamideIC50822.0 [1], 830.0 [2], 831.76 [3]
(1S,3R)-N-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-3-(2,3-dihydro-1H-inden-1-ylamino)-1-propan-2-ylcyclopentane-1-carboxamideIC5076.91 [1], 77.0 [2]
(1S,3R)-N-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-3-(2,3-dihydro-1H-inden-1-ylamino)-1-propan-2-ylcyclopentane-1-carboxamideKi50.0 [1]
[(1S,3R)-3-[[(3S,4S)-3-Methoxyoxan-4-yl]amino]-1-propan-2-ylcyclopentyl]-[4-[5-(trifluoromethyl)pyridazin-3-yl]piperazin-1-yl]methanoneIC507.7 [1], 8.1 [2], 25.7 [3]
N-(3,4-Dichlorophenyl)-4-[(2R)-4-propan-2-ylpiperazine-2-carbonyl]piperazine-1-carboxamideIC503.5 [1], 5.1 [2], 5.8 [3]
N-[2-[[(2S,3S)-1-[(2,4-Dimethylphenyl)methylamino]-3-hydroxyhexan-2-yl]amino]-2-oxoethyl]-2-(ethylcarbamoylamino)-5-(trifluoromethyl)benzamideIC503.6 [1], 24.0 [2]
3-[5-(3,5-Dichlorophenyl)-2-naphthalen-2-ylpyrazol-3-yl]oxy-N-[6-(diethylamino)-2-methylhexan-3-yl]propanamideIC506.0 [1], 32.0 [2]
3-[5-(3,5-Dichlorophenyl)-2-naphthalen-2-ylpyrazol-3-yl]oxy-N-[1-(diethylamino)-6-methylheptan-4-yl]propanamideIC5073.96 [1], 74.0 [2], 178.0 [3]
4-[5-(3,5-Dichlorophenyl)-2-naphthalen-2-ylpyrazol-3-yl]-N-[5-(diethylamino)pentan-2-yl]butanamideIC50108.0 [1], 209.0 [2], 6471.43 [3]
3-[5-(3,5-Dichlorophenyl)-2-naphthalen-2-ylpyrazol-3-yl]oxy-N-[1-(diethylamino)heptan-4-yl]propanamideIC5043.95 [1], 44.0 [2], 154.0 [3]
3-[5-(3,5-Dichlorophenyl)-2-naphthalen-2-ylpyrazol-3-yl]oxy-N-[6-(diethylamino)hexan-3-yl]propanamideIC508.99 [1], 9.0 [2], 83.0 [3]
(E)-1-[4-[(1S)-2-Hydroxy-1-[4-(1H-indol-3-yl)piperidin-1-yl]ethyl]piperidin-1-yl]-3-(3,4,5-trifluorophenyl)prop-2-en-1-oneIC502.4 [1], 3.5 [2], 2400.0 [3]
3-[5-(3,5-Dichlorophenyl)-2-naphthalen-2-ylpyrazol-3-yl]oxy-N-[5-(diethylamino)pentan-2-yl]propanamideIC5066.0 [1], 66.07 [2], 280.0 [3]
3-[[5-(3,5-Dichlorophenyl)-2-naphthalen-2-ylpyrazol-3-yl]amino]-N-[5-(diethylamino)pentan-2-yl]propanamideIC5029.99 [1], 30.0 [2], 54.0 [3]
1-Butyl-3-(2-methylpropyl)-9-(6-phenylhexyl)-1,4,9-triazaspiro[5.5]undecane-2,5-dione;hydrochlorideIC5010000.0 [1]
(2S)-2-(2-Acetamido-1,3-thiazol-4-yl)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-4-(4-phenylpiperidin-1-yl)butanamideIC500.7 [1], 1.8 [2], 1.82 [3]
3-[1-[5-(4-Biphenylylcarbonylamino)pentyl]-4-piperidinyl]-1H-indoleKi5300.0 [1], 5400.0 [2], 5495.41 [3]
(E)-3-(3,4-Dichlorophenyl)-N-[5-[(1R,5S)-3-(5-hydroxy-1H-indol-3-yl)-8-azabicyclo[3.2.1]octan-8-yl]pentyl]prop-2-enamideKi251.0 [1], 251.19 [2], 630.0 [3]
(2S)-N-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-2-cyclopropyl-4-[(1R,3'R)-3'-methylspiro[indene-1,4'-piperidine]-1'-yl]butanamideIC504.0 [1], 14.0 [2]
N-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-2-cyclopropyl-4-spiro[indene-1,4'-piperidine]-1'-ylbutanamideIC5038.0 [1], 69.0 [2], 97.72 [3]
N-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-4-[(1R,3'R)-3'-methylspiro[indene-1,4'-piperidine]-1'-yl]butanamideIC5093.0 [1], 173.0 [2], 213.8 [3]
(2S)-N-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-2-[2-(methylcarbamoylamino)-1,3-thiazol-4-yl]-4-(4-phenylpiperidin-1-yl)butanamideIC500.43 [1], 1.8 [2]
(2R)-N-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-2-[2-(methylcarbamoylamino)-1,3-thiazol-4-yl]-4-(4-phenylpiperidin-1-yl)butanamideIC5030.0 [1], 30.2 [2], 87.0 [3]
Methyl (2S)-5-(diaminomethylideneamino)-2-[3-[5-(3,5-dichlorophenyl)-2-naphthalen-2-ylpyrazol-3-yl]oxypropanoylamino]pentanoateIC5061.94 [1], 62.0 [2], 118.0 [3]
3-[5-(3,5-Dichlorophenyl)-2-naphthalen-2-ylpyrazol-3-yl]oxy-N-[1-(diethylamino)-6-methyloctan-4-yl]propanamideIC50106.91 [1], 107.0 [2], 225.0 [3]
N-[2-[[(3R)-1-[2-[4-(2-Chlorobenzoyl)piperazin-1-yl]ethyl]pyrrolidin-3-yl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamideIC501.7 [1], 23.0 [2], 1120.0 [3]
3,4-Dichloro-N-[5-chloro-2-(2-methylpyridin-3-yl)oxypyridin-3-yl]benzenesulfonamideKi10.0 [1], 1259.0 [2]
[(2R,3Ar,6aR)-2-[[(3R,4R)-3-methoxyoxan-4-yl]amino]-2,3,4,5,6,6a-hexahydro-1H-pentalen-3a-yl]-[3-(trifluoromethyl)-7,8-dihydro-5H-1,6-naphthyridin-6-yl]methanoneIC5024.0 [1], 49.0 [2], 61.0 [3]
2-(Diethylcarbamoylamino)-N-[2-[[(1S,2R)-2-[(4-methylsulfanylphenyl)sulfonylmethyl]cyclohexyl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamideIC506.5 [1], 34.0 [2], 39.5 [3]
2-Amino-N-[2-[[(2S)-1-(tert-butylamino)-3-[(2,4-dimethylphenyl)methylamino]-1-oxopropan-2-yl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamideIC508.0 [1], 11.0 [2], 260.0 [3]
N-[2-[[(1S,2R,4R)-4-Amino-2-[(4-methylsulfanylphenyl)sulfonylmethyl]cyclohexyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamideIC507.5 [1], 13.1 [2], 21.0 [3]
N-[2-[[(2S)-1-(Tert-butylamino)-3-[(2,4-dimethylphenyl)methylamino]-1-oxopropan-2-yl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamideIC5048.0 [1], 52.0 [2], 3000.0 [3]
N-[2-[[(2S)-1-Amino-3-[(2,4-dimethylphenyl)methylamino]-1-oxopropan-2-yl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamideIC5066.0 [1], 69.0 [2], 1500.0 [3]
N-[2-[[(2S)-1-(Tert-butylamino)-3-[(2,4-dimethylphenyl)methylamino]-1-oxopropan-2-yl]amino]-2-oxoethyl]-2-(ethylamino)-5-(trifluoromethyl)benzamideIC5013.0 [1], 84.0 [2], 100.0 [3]
Rac-3-Isobutyl-9-(4-phenoxybenzyl)-1-propyl-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochlorideIC5030000.0 [1]
N-[2-[[(1S,2R,4R)-2-[(4-Methylsulfanylphenyl)sulfonylmethyl]-4-(propan-2-ylamino)cyclohexyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamideIC502.05 [1], 5.1 [2], 10.4 [3]
N-[2-[[(1S,2R,4R)-4-[Methyl(propan-2-yl)amino]-2-[(4-methylsulfanylphenyl)sulfonylmethyl]cyclohexyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamideIC500.2 [1], 0.5 [2], 1.3 [3]
N-[2-[[(1S,2R,4R)-4-(Dimethylamino)-2-[(4-methylsulfanylphenyl)sulfonylmethyl]cyclohexyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamideIC500.3 [1], 0.37 [2], 2.5 [3]
2-(Dimethylcarbamoylamino)-N-[2-[[(1S,2R)-2-[(4-methylsulfanylphenyl)sulfonylmethyl]cyclohexyl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamideIC508.1 [1], 21.0 [2], 43.5 [3]
[(3S)-3-[[4-Hydroxy-4-(5-pyrimidin-2-ylpyridin-2-yl)cyclohexyl]amino]pyrrolidin-1-yl]-[1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl]methanoneIC504.3 [1], 5.4 [2], 29.0 [3]
[(3S)-3-[[4-Hydroxy-4-(5-pyrimidin-2-ylpyridin-2-yl)cyclohexyl]amino]pyrrolidin-1-yl]-[1-[6-(trifluoromethyl)pyridin-2-yl]piperidin-4-yl]methanoneIC504.5 [1], 8.8 [2], 88.0 [3]
[(3S)-3-[[4-Hydroxy-4-(5-pyrimidin-2-ylpyridin-2-yl)cyclohexyl]amino]pyrrolidin-1-yl]-[1-[3-(trifluoromethyl)phenyl]piperidin-4-yl]methanoneIC503.6 [1], 6.1 [2], 37.0 [3]
[(3S)-3-[[4-Hydroxy-4-(5-pyrimidin-2-ylpyridin-2-yl)cyclohexyl]amino]pyrrolidin-1-yl]-[1-[4-(trifluoromethyl)pyridin-2-yl]piperidin-4-yl]methanoneIC501.9 [1], 3.3 [2], 12.0 [3]
N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(1,3-thiazol-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamideIC501.8 [1], 6.0 [2], 67.0 [3]
N-[2-[(3S)-3-[[4-Hydroxy-4-(5-pyrazin-2-ylpyridin-2-yl)cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamideIC503.8 [1], 6.0 [2], 6.5 [3]
Unii-2bod5iud08IC5020.0 [1], 100.0 [2]
N-(3,4-Dichlorophenyl)-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamideIC50170.0 [1], 965.0 [2]
N-(3,4-Dichlorophenyl)-4-[(1-methylpiperidin-3-yl)methyl]piperazine-1-carboxamideKi400.0 [1]
3,4-Dichloro-N-[5-chloro-2-[(5-cyclopropyltetrazol-1-yl)methyl]phenyl]benzenesulfonamideKi31.62 [1], 100.0 [2]
2-(Methylcarbamoylamino)-N-[2-[[4-[(4-methylsulfanylphenyl)methylamino]-1-propylpiperidin-3-yl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamideIC503.0 [1], 3.8 [2], 8.0 [3]
N-[2-[[4-(Dimethylamino)-2-[(4-methylphenyl)methylamino]cyclohexyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamideIC505.5 [1], 9.9 [2], 12.6 [3]
2-Amino-N-[2-[[4-[(4-methylsulfanylphenyl)methylamino]-1-propylpiperidin-3-yl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamideIC502.0 [1], 3.4 [2], 5.4 [3]
2-Amino-N-[2-[[1-methyl-4-[(4-methylsulfanylbenzoyl)amino]piperidin-3-yl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamideIC501.8 [1], 2.0 [2], 38.5 [3]
N-[2-[[4-(Dimethylamino)-2-[(4-methylsulfanylphenyl)methylamino]cyclohexyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamideIC502.4 [1], 6.0 [2], 22.5 [3]
2-Amino-N-[2-[[1-butyl-4-[(4-methylsulfanylphenyl)methylamino]piperidin-3-yl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamideIC507.9 [1], 13.0 [2], 19.0 [3]
N-[2-[[4-(Dimethylamino)-2-[(4-methoxyphenyl)methylamino]cyclohexyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamideIC508.0 [1], 12.5 [2], 41.4 [3]
3-Amino-N-[2-[[4-[(4-methylsulfanylphenyl)methylamino]-1-propylpiperidin-3-yl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamideIC503.0 [1], 6.1 [2], 26.0 [3]
2-Amino-N-[2-[[1-methyl-4-[(4-methylsulfanylphenyl)methylamino]piperidin-3-yl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamideIC500.95 [1], 5.0 [2], 27.5 [3]
N-[2-[[2-[[4-[(4-Methylsulfanylphenyl)methylamino]-1-propylpiperidin-3-yl]amino]-2-oxoethyl]carbamoyl]-4-(trifluoromethyl)phenyl]pyrrolidine-1-carboxamideIC504.8 [1], 8.7 [2], 21.0 [3]
N-[2-[[(1S,2R)-2-[(4-Chlorophenyl)methylamino]cyclohexyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamideIC50268.0 [1], 790.0 [2], 2117.2 [3]
2,4-Dimethyl-N-[(1R,2S)-2-[[2-[[3-(trifluoromethyl)benzoyl]amino]acetyl]amino]cyclohexyl]benzamideIC504130.0 [1], 7847.0 [2]
N-[2-[[(1S,2R)-2-[(4-Iodobenzoyl)amino]cyclohexyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamideIC5030.0 [1], 37.0 [2], 160.0 [3]



References

This online tool may be cited as follows

MLA

"Quest Database™ C-C chemokine receptor type 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Nov2024https://www.aatbio.com/data-sets/c-c-chemokine-receptor-type-2-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024November 21). Quest Database™ C-C chemokine receptor type 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/c-c-chemokine-receptor-type-2-inhibitors-ic50-ki.
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