![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_fa516af55796fcea8972783ed0bcbca2.svg) | 1-[(2R)-1-[(4S)-4-(4-Chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl]-3-(2-hydroxy-2-methylpropyl)urea | IC50 | 6.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_8ab508b68420735dbf3f9af2c10e13ef.svg) | 1-[4-(4-Chloro-3-methoxyphenyl)piperazin-1-yl]-2-[4-chloro-5-methyl-3-(trifluoromethyl)pyrazol-1-yl]ethanone | IC50 | 3.9 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_289fa4e2dabc549d88b92d65d5312c6f.svg) | (1R,3R)-N-[(2R)-1-[(4S)-4-(4-Chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl]-3-hydroxycyclopentane-1-carboxamide | IC50 | 4.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_bc3bfc8641a25283f4e7a76819007cf9.svg) | BX-471 free base | IC50 | 1.5 [1], 5.5 [2], 18.0 [3], 31.0 [4] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_bc3bfc8641a25283f4e7a76819007cf9.svg) | BX-471 free base | Ki | 1.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_77bbd3fbb4d9ea81bf9ec048efece74b.svg) | N-[(2R)-1-[4-(4-Chlorophenyl)piperidin-1-yl]-3-methyl-1-oxobutan-2-yl]benzamide | IC50 | 15.0 [1], 78.0 [2], 85.0 [3] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_3a9f9eb7bff4267639d086824c3cb39e.svg) | BX471 (hydrochloride) | IC50 | 0.4 [1], 2.36 [2], 40.0 [3], 550.0 [4] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_abe932b92164f1825530a277149f7423.svg) | 5-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidyl]-2,2-diphenyl-pentanenitrile | IC50 | 48.0 [1], 630.0 [2], 2500.0 [3] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_abe932b92164f1825530a277149f7423.svg) | 5-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidyl]-2,2-diphenyl-pentanenitrile | Ki | 52.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_5c658800bc879541778f93ff0cbe42b5.svg) | N-[(2S,3S,5R)-1-Cyclohexyl-3-hydroxy-7-methyl-5-(methylcarbamoyl)octan-2-yl]quinoline-3-carboxamide | IC50 | 840.0 [1], 2280.0 [2], 2300.0 [3] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_66b2d41faceae6994e90680b29d702fe.svg) | J-113863 Cation, trans- | IC50 | 0.73 [1], 0.9 [2], 47.0 [3] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_f3184d2681565123cc6115506b8c1d84.svg) | (2R)-2-N-[(4-Chlorophenyl)methyl]-2-N-methyl-1-N-[4-(trifluoromethyl)phenyl]pyrrolidine-1,2-dicarboxamide | IC50 | 22.0 [1], 140.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_cd05b74d64a8f4cab026687be2f2a6a7.svg) | N-[5-Chloro-2-[(E)-3-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]-3-oxoprop-1-enyl]-4-methoxyphenyl]acetamide | IC50 | 1.5 [1], 4.0 [2], 20.0 [3], 69.7 [4] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_143f30cf0aad84f7b8b300cc43fffab1.svg) | N-[5-Chloro-2-[(E)-3-[3-[(4-fluorophenyl)methyl]-3,8-diazabicyclo[3.2.1]octan-8-yl]-3-oxoprop-1-enyl]phenyl]-2-(dimethylamino)acetamide | IC50 | 9.0 [1], 10.0 [2], 30.0 [3], 41.0 [4] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_84b2880accb12d5f80da3786c0d26c9a.svg) | N-[5-Chloro-2-[(E)-3-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]-3-oxoprop-1-enyl]phenyl]acetamide | IC50 | 1.0 [1], 9.97 [2], 30.0 [3], 320.0 [4] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_94aa2cf7d4601ba9a46e5799b719ceb1.svg) | N-[5-Chloro-2-[(E)-3-[3-[(4-fluorophenyl)methyl]-3,8-diazabicyclo[3.2.1]octan-8-yl]-3-oxoprop-1-enyl]-4-methoxyphenyl]acetamide | IC50 | 0.0 [1], 1.0 [2], 7.0 [3], 7.5 [4] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_cd7ddbff3e434314ab8905fc385dac47.svg) | [5-Chloro-2-[(E)-3-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]-3-oxoprop-1-enyl]phenyl]urea | IC50 | 0.9 [1], 16.0 [2], 40.0 [3], 45.0 [4] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_56a4a369eea587589dcbbd2cb1287cf1.svg) | N-[(2R)-1-[(4S)-4-(4-Chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl]-3-hydroxy-3-methylbutanamide | IC50 | 3.0 [1], 5.2 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_56a4a369eea587589dcbbd2cb1287cf1.svg) | N-[(2R)-1-[(4S)-4-(4-Chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl]-3-hydroxy-3-methylbutanamide | Ki | 3.7 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_91d902e108a2f3c6aadfe697e85088dc.svg) | N-[(2S,3S,5R)-5-Carbamoyl-3-hydroxy-8-methyl-1-phenylnonan-2-yl]quinoxaline-2-carboxamide | IC50 | 2.0 [1], 28.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_f39dc31e7779504729ee7fbf425445d3.svg) | N-[2-[(2S)-3-(5-Fluorospiro[3H-1-benzofuran-2,4'-piperidine]-1'-yl)-2-hydroxypropoxy]-4-hydroxyphenyl]acetamide | IC50 | 0.52 [1], 2.6 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_b0da8a98c9c3dc2fe1dc7595bad3c408.svg) | N-[2-[(2S)-3-(5-Chlorospiro[3H-1-benzofuran-2,4'-piperidine]-1'-yl)-2-hydroxypropoxy]-4-hydroxyphenyl]acetamide | IC50 | 0.36 [1], 2.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_f67477a6d8fc71ec528f4b02be5fc585.svg) | N-(2-(3-(4-(4-Fluorobenzyl)piperazin-1-yl)-3-oxoprop-1-enyl)-5-chlorophenyl)acetamide | IC50 | 58.0 [1], 150.0 [2], 190.0 [3] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_b64b19fe504fd6c5ebc98645c2a54ae6.svg) | N-[5-Chloro-2-[(E)-3-[(2S,5R)-4-[(4-fluorophenyl)methyl]-2,5-dimethylpiperazin-1-yl]-3-oxoprop-1-enyl]phenyl]acetamide | IC50 | 1.0 [1], 100.0 [2], 10500.0 [3] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_ae778abdb832356d2a82e5ca771de200.svg) | N-[6-[(E)-3-[(2R)-4-[(4-Fluorophenyl)methyl]-2-methylpiperazin-1-yl]-3-oxoprop-1-enyl]quinolin-7-yl]acetamide | IC50 | 20.0 [1], 30.0 [2], 300.0 [3] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_186dda7c931a407ed62605b51bc27121.svg) | (R)-N-(3-(3-(4-(4-Fluorobenzyl)-2-methylpiperazin-1-yl)-3-oxoprop-1-enyl)naphthalen-2-yl)acetamide | IC50 | 13.0 [1], 80.0 [2], 1500.0 [3] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_773e3c5ca465bbdf90d2d38f574ffbd1.svg) | N-[5-Chloro-2-[(E)-3-[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethylpiperazin-1-yl]-3-oxoprop-1-enyl]phenyl]acetamide | IC50 | 0.1 [1], 9.0 [2], 1350.0 [3] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_bc7d0aeeb838ebfc393bcd0c7a7dc817.svg) | 2-[4-Chloro-5-methyl-3-(trifluoromethyl)pyrazol-1-yl]-1-[4-(4-fluorophenyl)piperazin-1-yl]ethanone | IC50 | 93.0 [1], 307.0 [2], 310.0 [3] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_b2c8e13cb69881dbb06b72b9bd0d4b7b.svg) | 3-Amino-4-[5-chloro-2-[2-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]-2-oxoethoxy]anilino]cyclobut-3-ene-1,2-dione | IC50 | 4.0 [1], 7.0 [2], 10.0 [3] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_dd3597104082ca82f53a3d2228eb9b34.svg) | N-[5-Chloro-2-[[2-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]-2-oxoethyl]amino]phenyl]acetamide | IC50 | 2.4 [1], 50.0 [2], 1700.0 [3] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_4a010d2301cfb17e3bb568adf27f5d7c.svg) | N-[5-Chloro-2-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazine-1-carbonyl]-1H-indol-7-yl]acetamide | IC50 | 9.6 [1], 560.0 [2], 1000.0 [3] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_a817887357e0076d5c46a9be299e0b4b.svg) | N-[5-Chloro-2-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazine-1-carbonyl]-1-benzofuran-7-yl]acetamide | IC50 | 28.0 [1], 120.0 [2], 1000.0 [3] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_aa8017789658207dc8c49b819575dbd8.svg) | 3-[5-Chloro-2-[2-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]-2-oxoethoxy]anilino]-4-(methylamino)cyclobut-3-ene-1,2-dione | IC50 | 17.0 [1], 18.0 [2], 26.0 [3] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_f574614111b1ac6c84b09b4bf788067a.svg) | 3-[5-Bromo-2-[2-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]-2-oxoethoxy]anilino]-4-(methylamino)cyclobut-3-ene-1,2-dione | IC50 | 14.0 [1], 25.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_38645583a3c08b99e8b3835541da2eaa.svg) | 3-[5-Chloro-2-[2-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]-2-oxoethoxy]anilino]-4-(2-methoxyethylamino)cyclobut-3-ene-1,2-dione | IC50 | 19.0 [1], 54.0 [2], 63.0 [3] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_dc681034c2a27e33bbca9a1aec7612bc.svg) | 3-[5-Chloro-2-[2-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]-2-oxoethoxy]anilino]-4-(2-hydroxyethylamino)cyclobut-3-ene-1,2-dione | IC50 | 13.0 [1], 20.0 [2], 47.0 [3] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_8b874f7ee4384402eb035fed3cc58729.svg) | 3-(2-Aminoethylamino)-4-[5-chloro-2-[2-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]-2-oxoethoxy]anilino]cyclobut-3-ene-1,2-dione | IC50 | 6.0 [1], 18.0 [2], 23.0 [3] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_0d71c4badedb92cd89cf291ae7855c97.svg) | 3-[5-Chloro-2-[2-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]-2-oxoethoxy]anilino]-4-(2-morpholin-4-ylethylamino)cyclobut-3-ene-1,2-dione | IC50 | 12.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_f5e64abb22511b5434ed886bb83e5db3.svg) | 3-[5-Chloro-2-[2-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]-2-oxoethoxy]anilino]-4-(2-piperazin-1-ylethylamino)cyclobut-3-ene-1,2-dione | IC50 | 5.0 [1], 39.0 [2], 50.0 [3] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_bc67fdcc62a2b778f1f075d5cd19b356.svg) | 3-[5-Chloro-2-[2-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]-2-oxoethoxy]anilino]-4-(pyridin-3-ylmethylamino)cyclobut-3-ene-1,2-dione | IC50 | 8.0 [1], 38.0 [2], 42.0 [3] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_2a7cdf9ce8765295945d912c162d0bd3.svg) | 6-[2-(Dimethylamino)ethyl-methylamino]-1,3-dimethyl-N-[(3-propan-2-yloxyphenyl)carbamoyl]pyrazolo[3,4-b]pyridine-5-carboxamide;hydrochloride | IC50 | 10000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_4240103d3f7ab0441ea11324410bf073.svg) | 1-[(2R)-Butan-2-yl]-3-[(2R)-1-[(4S)-4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl]urea | IC50 | 3.0 [1], 6.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_4240103d3f7ab0441ea11324410bf073.svg) | 1-[(2R)-Butan-2-yl]-3-[(2R)-1-[(4S)-4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl]urea | Ki | 2.1 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_81b9308556cc341ce5df2fb5baaf65e2.svg) | N-[(2R)-1-[(4S)-4-(4-Chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl]-3-methylbutanamide | IC50 | 1.9 [1], 2.9 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_81b9308556cc341ce5df2fb5baaf65e2.svg) | N-[(2R)-1-[(4S)-4-(4-Chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl]-3-methylbutanamide | Ki | 2.6 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_4e6bdc7116d2046416141f8adddeb91a.svg) | N-[(2R)-1-[(4S)-4-(4-Chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl]cyclopentanecarboxamide | IC50 | 1.4 [1], 2.5 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_4e6bdc7116d2046416141f8adddeb91a.svg) | N-[(2R)-1-[(4S)-4-(4-Chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl]cyclopentanecarboxamide | Ki | 0.7 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_623a952b16824ec0b823c11235a2fa3b.svg) | N-[(2S,3S,5R)-3-Hydroxy-7-methyl-5-(methylcarbamoyl)-1-phenyloctan-2-yl]quinoline-3-carboxamide | IC50 | 650.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_316f50042881cb569d1c047713974e36.svg) | 1-(5-Amino-4,4-diphenyl-pentyl)-4-(4-chloro-phenyl)-piperidin-4-ol | IC50 | 760.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_316f50042881cb569d1c047713974e36.svg) | 1-(5-Amino-4,4-diphenyl-pentyl)-4-(4-chloro-phenyl)-piperidin-4-ol | Ki | 244.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_49be6ce38b9189a33f2a2b9749b9448c.svg) | 2-(Benzothiazol-2-ylsulfanyl)-N-[1-(3,4-dichloro-benzyl)-piperidin-4-yl]-acetamide | IC50 | 450.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_520a84272c2d2dbe23697ec7948ba7f7.svg) | 5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2-phenyl-2-piperidin-1-yl-pentanenitrile | IC50 | 4800.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_520a84272c2d2dbe23697ec7948ba7f7.svg) | 5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2-phenyl-2-piperidin-1-yl-pentanenitrile | Ki | 130.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_3347d3467e26667db37185dfb67a8e5b.svg) | 5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2-thiophen-2-yl-pentanenitrile | IC50 | 8400.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_3347d3467e26667db37185dfb67a8e5b.svg) | 5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2-thiophen-2-yl-pentanenitrile | Ki | 128.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_e24e60d37945434396d534ec6885247d.svg) | 2-{4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-cyano-butyl}-benzonitrile | IC50 | 5800.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_e24e60d37945434396d534ec6885247d.svg) | 2-{4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-cyano-butyl}-benzonitrile | Ki | 98.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_29d7f1b4a2a1ab0260c094604e090fb7.svg) | 6-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-hexanenitrile | IC50 | 1600.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_29d7f1b4a2a1ab0260c094604e090fb7.svg) | 6-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-hexanenitrile | Ki | 78.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_8054a9804cb9f69a06b83e03b4b07b80.svg) | 7-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-heptanenitrile | IC50 | 5600.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_8054a9804cb9f69a06b83e03b4b07b80.svg) | 7-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-heptanenitrile | Ki | 99.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_9b1847a12ce4345b6fe8d85c1099b101.svg) | 11-[3-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]propyl]-5-methyl-6-oxobenzo[c][1]benzazepine-11-carbonitrile | IC50 | 3300.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_9b1847a12ce4345b6fe8d85c1099b101.svg) | 11-[3-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]propyl]-5-methyl-6-oxobenzo[c][1]benzazepine-11-carbonitrile | Ki | 32.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_4f22b664ea83c0028a090f200891084b.svg) | 5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2-thiophen-3-yl-pentanenitrile | IC50 | 9800.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_4f22b664ea83c0028a090f200891084b.svg) | 5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2-thiophen-3-yl-pentanenitrile | Ki | 236.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_001aa525b1442df0a1a4fff3773fd560.svg) | Ethyl 5-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2-cyano-2-phenylpentanoate | IC50 | 7000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_001aa525b1442df0a1a4fff3773fd560.svg) | Ethyl 5-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2-cyano-2-phenylpentanoate | Ki | 33.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_9bfcba1e2029fa53c01606d9bac1e575.svg) | 2-(3-Bromo-4-methoxy-phenyl)-5-[4-(4-chloro-phenyl)-4-hydroxy-piperidin-1-yl]-pentanenitrile | IC50 | 1900.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_9bfcba1e2029fa53c01606d9bac1e575.svg) | 2-(3-Bromo-4-methoxy-phenyl)-5-[4-(4-chloro-phenyl)-4-hydroxy-piperidin-1-yl]-pentanenitrile | Ki | 74.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_3bfaa4be6d2af3828d481bb12a91f66f.svg) | 4-[1-(4-Cyano-4,4-diphenylbutyl)-4-hydroxypiperidin-4-yl]benzonitrile | IC50 | 10900.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_3bfaa4be6d2af3828d481bb12a91f66f.svg) | 4-[1-(4-Cyano-4,4-diphenylbutyl)-4-hydroxypiperidin-4-yl]benzonitrile | Ki | 92.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_2928b21e51ea5fa24f89deeae5e4b89a.svg) | 5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2-(3-chloro-propyl)-2-phenyl-pentanenitrile | IC50 | 8300.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_2928b21e51ea5fa24f89deeae5e4b89a.svg) | 5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2-(3-chloro-propyl)-2-phenyl-pentanenitrile | Ki | 51.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_ea54b90b830408294dbf71329e9f607e.svg) | 2-{3-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-propyl}-2-phenyl-succinonitrile | IC50 | 3200.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_ea54b90b830408294dbf71329e9f607e.svg) | 2-{3-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-propyl}-2-phenyl-succinonitrile | Ki | 125.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_7597038e5ddd6d5daee99c3618fdcac6.svg) | 5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2-(3-hydroxy-phenyl)-pentanenitrile | IC50 | 9000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_7597038e5ddd6d5daee99c3618fdcac6.svg) | 5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2-(3-hydroxy-phenyl)-pentanenitrile | Ki | 156.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_e6a10b09f982874e50625eb07da9f295.svg) | 1-[(2R)-1-[(4S)-4-(4-Chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl]-3-[(1R,3S)-3-hydroxycyclopentyl]urea | IC50 | 2.0 [1], 4.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_cd67f83f4d6f54444d5ab76733e3c3eb.svg) | 1-[(2R)-1-[(4S)-4-(4-Chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl]-3-[(2S)-2-hydroxypropyl]urea | IC50 | 2.0 [1], 7.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_608e115fe63262e89da08f9341248b82.svg) | 1-[(2R)-1-[(4S)-4-(4-Chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl]-3-[(2R)-2-hydroxypropyl]urea | IC50 | 2.0 [1], 6.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_890ac1e75f1560f1f51e2026567bec20.svg) | N-[(2R)-1-[(4S)-4-(4-Chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl]-3-methyl-1-oxobutan-2-yl]-4-hydroxy-4-methylpentanamide | IC50 | 2.0 [1], 22.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_e251699c2ae4e6eef6c4703ea800c984.svg) | N-[(2R)-1-[4-(4-Chlorophenyl)-3,3-dimethylpiperazin-1-yl]-3-methyl-1-oxobutan-2-yl]cyclopentanecarboxamide | IC50 | 4.1 [1], 18.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_e43f0bed183c447e88726bd04e2ecdac.svg) | (2R)-2-N-[(4-Chlorophenyl)methyl]-2-N-methyl-1-N-[2-methyl-4-(trifluoromethyl)phenyl]pyrrolidine-1,2-dicarboxamide | IC50 | 16.0 [1], 50.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_128922a2c2a8fe86c5091ea9ee465c19.svg) | 1-[1-(2-Bromophenyl)sulfonylpiperidin-4-yl]-4-(4-chlorophenyl)piperidin-4-ol | IC50 | 90.0 [1] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_89340e43b0e853ac78ac5f262e6188eb.svg) | (2R)-2-N-[(4-Chlorophenyl)methyl]-1-N-(4-methoxyphenyl)-2-N-methylpyrrolidine-1,2-dicarboxamide | IC50 | 290.0 [1], 440.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_03cd04fc495d14e652e84197cdd595ee.svg) | (2R)-2-N-[(4-Chlorophenyl)methyl]-1-N-[2-chloro-4-(trifluoromethyl)phenyl]-2-N-methylpyrrolidine-1,2-dicarboxamide | IC50 | 35.0 [1], 120.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_775886009e587bafcae356a3da48c489.svg) | (2R)-2-N-[(4-Chlorophenyl)methyl]-1-N-[2-fluoro-4-(trifluoromethyl)phenyl]-2-N-methylpyrrolidine-1,2-dicarboxamide | IC50 | 22.0 [1], 23.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_0756dd383e36372f09066cc620b5ef6f.svg) | (2R)-2-N-[(4-Chlorophenyl)methyl]-1-N-[2,6-dimethyl-4-(trifluoromethyl)phenyl]-2-N-methylpyrrolidine-1,2-dicarboxamide | IC50 | 6.0 [1], 11.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_cab18663169f123ac40b624ad56b9cce.svg) | (2R)-2-[4-[(4-Chlorophenyl)methyl]-1,2,4-triazol-3-yl]-N-[4-(trifluoromethyl)phenyl]pyrrolidine-1-carboxamide | IC50 | 4.0 [1], 17.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_aa0df29f3ab84a0bae7a8ef4ee7856e2.svg) | (2R)-2-[1-[(4-Chlorophenyl)methyl]tetrazol-5-yl]-N-[4-(trifluoromethyl)phenyl]pyrrolidine-1-carboxamide | IC50 | 6.5 [1], 20.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_f9bd6082768f2c6bde7619e9b4d4605b.svg) | (2R)-2-[2-[(4-Chlorophenyl)methyl]-1,2,4-triazol-3-yl]-N-[4-(trifluoromethyl)phenyl]pyrrolidine-1-carboxamide | IC50 | 22.0 [1], 32.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_45f8b043ba3088490c1c62ed14df3be7.svg) | N-[(2S,3S)-8-Fluoro-3-hydroxy-8-methyl-5-(4-methylpiperazine-1-carbonyl)-1-phenylnonan-2-yl]quinoxaline-2-carboxamide | IC50 | 5600.0 [1], 7050.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_aa9e03c3ca6138f390f52c22b71a7b4e.svg) | N-[(2S,3S)-8-Fluoro-3-hydroxy-5-(hydroxycarbamoyl)-8-methyl-1-phenylnonan-2-yl]quinoxaline-2-carboxamide | IC50 | 27.0 [1], 31.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_b636a818174a2a7118e0bac46c9ae0d6.svg) | N-[(2S,3S)-8-Fluoro-3-hydroxy-8-methyl-1-phenyl-5-(pyrrolidine-1-carbonyl)nonan-2-yl]quinoxaline-2-carboxamide | IC50 | 740.0 [1], 2320.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_7595ad1f8e0a018d5c89a6d0c35f8b70.svg) | N-[(2S,3S)-8-Fluoro-5-(hydrazinecarbonyl)-3-hydroxy-8-methyl-1-phenylnonan-2-yl]quinoxaline-2-carboxamide | IC50 | 1.0 [1], 7.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_cb2d5fb6b7543eabd2c191e384354438.svg) | N-[(2S,3S)-6-Amino-3-hydroxy-5-(oxan-4-yl)-6-oxo-1-phenylhexan-2-yl]quinoxaline-2-carboxamide | IC50 | 3460.0 [1], 12500.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_b1f0223d59356f87a43a6fa626156b60.svg) | N-[(2S,3S,5R)-5-Carbamoyl-3,8-dihydroxy-8-methyl-1-phenylnonan-2-yl]quinoxaline-2-carboxamide | IC50 | 580.0 [1], 1180.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_ffe39f18259a7632e2477f0c1a992513.svg) | N-[(2S,3S)-6-Amino-5-(4,4-difluorocyclohexyl)-3-hydroxy-6-oxo-1-phenylhexan-2-yl]quinoxaline-2-carboxamide | IC50 | 20.0 [1], 220.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_883b940eb1e2fd99f75b7319ffbd03be.svg) | N-[(2S,3S)-6-Amino-5-(4,4-difluoro-1-hydroxycyclohexyl)-3-hydroxy-6-oxo-1-phenylhexan-2-yl]quinoxaline-2-carboxamide | IC50 | 68.0 [1], 560.0 [2] |
![](https://images.aatbio.com/dataset/ic50/c-c-chemokine-receptor-type-1_67002d50189b0b7abb30a3bc6e33d6af.svg) | N-[(2S,3S)-5-(Benzylcarbamoyl)-8-fluoro-3-hydroxy-8-methyl-1-phenylnonan-2-yl]quinoxaline-2-carboxamide | IC50 | 440.0 [1], 850.0 [2] |