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Bloom syndrome protein Inhibitors (IC50, Ki)

Structure
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▼
Compound Name
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Standard Type
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Standard Values (in nM)
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▼
1-[4-Fluoro-3-(trifluoromethyl)phenyl]-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC501800.0 [1], 3000.0 [2], 50000.0 [3]
1-[3-Cyano-4-(1H-pyrazol-4-yl)phenyl]-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC501100.0 [1]
1-(3,4-Dichlorophenyl)-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC501400.0 [1]
1-(4-Chloro-phenyl)-3-(5-pyridin-4-yl-[1,3,4]thiadiazol-2-yl)-ureaIC5040000.0 [1]
1-(4-Fluorophenyl)-3-[5-(pyridin-4-yl)-1,3,4-thiadiazol-2-yl]ureaIC5014100.0 [1]
1-(4-Cyanophenyl)-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC507900.0 [1]
1-[4-Chloro-3-(trifluoromethyl)phenyl]-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC507100.0 [1]
1-(4-Bromo-3-methylphenyl)-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC5013400.0 [1]
1-(3,4-Dichlorophenyl)-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)thioureaIC504000.0 [1]
1-(4-Fluoro-3-methylphenyl)-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC5015800.0 [1]
1-(4-Chloro-3-nitrophenyl)-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC501300.0 [1]
1-(3,4-Difluorophenyl)-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC508900.0 [1]
1-(3-Cyanophenyl)-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC508900.0 [1]
1-[4-Cyano-3-(trifluoromethyl)phenyl]-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC505600.0 [1]
1-(3,4-Dichlorophenyl)-2-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)guanidineIC5014100.0 [1]
1-(4-Bromophenyl)-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC5012600.0 [1]
1-(3,4-Dibromophenyl)-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC502100.0 [1]
1-(3-Cyano-4-fluorophenyl)-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC50300.0 [1]
1-(3-Chloro-4-cyanophenyl)-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC501600.0 [1]
1-(4-Cyano-3-methylphenyl)-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC503200.0 [1]
1-(4-Chloro-3-cyanophenyl)-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC50100.0 [1]
3-(3,4-Dichloroanilino)-4-[(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)amino]cyclobut-3-ene-1,2-dioneIC504300.0 [1]
1-[5-(4-Aminophenyl)-1,3,4-thiadiazol-2-yl]-3-(3,4-dichlorophenyl)ureaIC5049000.0 [1]
1-(3-Bromo-4-cyanophenyl)-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC50910.0 [1]
1-(3-Amino-4-chlorophenyl)-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC5011200.0 [1]
1-(3,4-Dichlorophenyl)-3-(6-pyridin-4-ylpyridin-2-yl)ureaIC504000.0 [1]
1-(3,4-Dichlorophenyl)-3-(5-pyridin-3-yl-1,3,4-thiadiazol-2-yl)ureaIC503500.0 [1]
1-[3-Methyl-4-(1H-pyrazol-4-yl)phenyl]-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC5016800.0 [1]
1-[4-(1H-Pyrazol-4-yl)-3-(trifluoromethyl)phenyl]-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC5014200.0 [1]
1-(3-Fluoro-4-imidazol-1-ylphenyl)-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC5010000.0 [1]
1-(5-Pyridin-4-yl-1,3,4-thiadiazol-2-yl)-3-[4-(1,2,4-triazol-1-yl)-3-(trifluoromethyl)phenyl]ureaIC5036000.0 [1]
1-(4-Bromo-3-cyanophenyl)-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC50110.0 [1]
1-[3-Fluoro-4-(1,2,4-triazol-1-yl)phenyl]-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC5014100.0 [1]
1-[4-Amino-3-(trifluoromethyl)phenyl]-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC5040000.0 [1]
1-(3,4-Dichlorophenyl)-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)ureaIC5028100.0 [1]
1-[3-Cyano-4-(1H-pyrrol-2-yl)phenyl]-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC501800.0 [1]
1-(4-Chloro-3-methylphenyl)-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaIC507900.0 [1]
Items per page: 1 - 10 of 37
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References

This online tool may be cited as follows

MLA

"Quest Database™ Bloom syndrome protein Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/bloom-syndrome-protein-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Bloom syndrome protein Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/bloom-syndrome-protein-inhibitors-ic50-ki.
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