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Betaine transporter Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
gamma-Aminobutyric acidIC509000.0 [1], 25000.0 [2], 36000.0 [3], 39000.0 [4], 181000.0 [5]
(S)-Snap 5114IC5071700.0 [1], 140000.0 [2], 141253.75 [3]
N-(1-Benzylpiperidin-4-yl)-2,4-dichlorobenzamideIC502000.0 [1], 13489.63 [2], 58000.0 [3], 1000000.0 [4]
1-[3-(9H-Carbazol-9-yl)propyl]-4-(2-methoxyphenyl)piperidin-4-olIC505100.0 [1]
N-(1-Benzylpiperidin-4-yl)-2,6-dichloropyridine-3-carboxamideIC5044000.0 [1], 1000000.0 [2]
TiagabineIC501670000.0 [1]
Nipecotic acidIC502370000.0 [1]
N-(4,4-Diphenyl-3-butenyl)nipecotic acidIC507210000.0 [1]
GuvacineIC501870000.0 [1]
1-{2-[Tris-(4-methoxy-phenyl)-methoxy]-ethyl}-piperidine-3-carboxylic acidIC50208000.0 [1]
(R)-Piperidine-3-carboxylic acidIC502310000.0 [1]
CI-966 Free baseIC50300000.0 [1]
(S)-Piperidine-3-carboxylic acidIC506410000.0 [1]
N-(1-Benzylpiperidin-4-yl)benzamideIC50290000.0 [1]
1-(3-(9H-Carbazol-9-yl)propyl)-4-(4-methoxyphenyl)piperidin-4-olKi1600.0 [1]
2-Ethoxy-N-[1-(phenylmethyl)-4-piperidinyl]benzamideIC50180000.0 [1]
1-{2-[9-(4-Methoxy-phenyl)-9H-fluoren-9-yloxy]-ethyl}-piperidine-3-carboxylic acidIC5027000.0 [1]
N-(1-Benzylpiperidin-4-yl)-2,3-dimethoxybenzamideIC5091000.0 [1]
N-(1-Benzylpiperidine-4-yl)-2-naphthamideKi15000.0 [1]
1-(4,4-Diphenyl-but-3-enyl)-piperidine-3-carboxylic acidIC507210000.0 [1]
N-(1-Benzylpiperidin-4-yl)-4-fluorobenzamideIC50100000.0 [1]
1-[2-[[4-Methoxy-3-(trifluoromethyl)phenyl]-phenyl-[3-(trifluoromethyl)phenyl]methoxy]ethyl]piperidine-3-carboxylic acidIC50201000.0 [1]
1-{2-[Tris-(4-fluoro-phenyl)-methoxy]-ethyl}-piperidine-3-carboxylic acidIC501270000.0 [1]
1-[2-[Bis(4-fluorophenyl)-(4-methoxyphenyl)methoxy]ethyl]piperidine-3-carboxylic acidIC50151000.0 [1]
1-{2-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-ethyl}-piperidine-3-carboxylic acidIC50382000.0 [1]
1-[2-(9-Phenyl-9H-xanthen-9-yloxy)-ethyl]-piperidine-3-carboxylic acidIC50920000.0 [1]
1-{2-[(4-Methoxy-phenyl)-diphenyl-methoxy]-ethyl}-piperidine-3-carboxylic acidIC50655000.0 [1]
1-[2-[(4-Methoxyphenyl)-bis(4-methylphenyl)methoxy]ethyl]piperidine-3-carboxylic acidIC50109000.0 [1]
1-[2-[Bis(4-chlorophenyl)-(4-methoxyphenyl)methoxy]ethyl]piperidine-3-carboxylic acidIC5088000.0 [1]
1-(2-Tritylsulfanyl-ethyl)-piperidine-3-carboxylic acidIC50435000.0 [1]
CID 118711599IC50590.0 [1]
2,4-Dichloro-N-[1-(pyridin-3-ylmethyl)piperidin-4-yl]benzamideIC501000000.0 [1]
2,4-Dichloro-N-[1-[(4-nitrophenyl)methyl]piperidin-4-yl]benzamideIC50100000.0 [1]
2,4-Dichloro-N-(1-phenacylpiperidin-4-yl)benzamideIC50100000.0 [1]
2,4-Dichloro-N-[1-[(E)-3-phenylprop-2-enyl]piperidin-4-yl]benzamideIC50100000.0 [1]
2,4-Dichloro-N-[1-(naphthalen-2-ylmethyl)piperidin-4-yl]benzamideIC5050000.0 [1]
2,4-Dichloro-N-[1-[(4-iodophenyl)methyl]piperidin-4-yl]benzamideIC50100000.0 [1]
2,4-Dichloro-N-[1-(3-diethoxyphosphorylpropyl)piperidin-4-yl]benzamideIC501000000.0 [1]
Methyl 4-[[4-[(2,4-dichlorobenzoyl)amino]piperidin-1-yl]methyl]benzoateIC50100000.0 [1]
2,4-Dichloro-N-[1-(pyridin-4-ylmethyl)piperidin-4-yl]benzamideIC501000000.0 [1]
2,4-Dichloro-N-[1-(3-cyanopropyl)piperidin-4-yl]benzamideIC501000000.0 [1]
Tert-butyl 2-[4-[(2,4-dichlorobenzoyl)amino]piperidin-1-yl]acetateIC501000000.0 [1]
2,4-Dichloro-N-(1-prop-2-ynylpiperidin-4-yl)benzamideIC501000000.0 [1]
2-[4-[(2,4-Dichlorobenzoyl)amino]piperidin-1-yl]acetic acidIC501000000.0 [1]
2,4-Dichloro-N-[1-[(2-cyanophenyl)methyl]piperidin-4-yl]benzamideIC5050000.0 [1]
2,4-Dichloro-N-[1-[(2-nitrophenyl)methyl]piperidin-4-yl]benzamideIC50100000.0 [1]
2,4-Dichloro-N-[1-[(4-cyanophenyl)methyl]piperidin-4-yl]benzamideIC5050000.0 [1]
2,4-Dichloro-N-[1-(quinolin-2-ylmethyl)piperidin-4-yl]benzamideIC5050000.0 [1]
N-(1-Benzylpiperidin-4-yl)-2-methylpropanamideIC501000000.0 [1]
2,4-Dichloro-N-(1-propylpiperidin-4-yl)benzamideIC501000000.0 [1]
2,4-Dichloro-N-(1-ethylpiperidin-4-yl)benzamideIC501000000.0 [1]
N-(1-Benzylpiperidin-4-yl)-3-(trifluoromethyl)benzamideIC50170000.0 [1]
CID 43345728IC501000000.0 [1]
2,4-Dichloro-N-[1-(pyridin-2-ylmethyl)piperidin-4-yl]benzamideIC501000000.0 [1]
(3R)-1-[(E)-4-(2-Fluorophenyl)-4-(2-methylphenyl)but-3-enyl]piperidine-3-carboxylic acidIC50100000.0 [1]
2-[(1S,2S)-2-Aminocyclopropyl]acetic acidIC505480.0 [1]
2,4-Dichloro-N-(1-methylpiperidin-4-yl)benzamideIC501000000.0 [1]
(R)-1-{2-[Tris-(4-methoxy-phenyl)-methoxy]-ethyl}-piperidine-3-carboxylic acidIC50630000.0 [1]
2-[(1S,2R)-2-Aminocyclopropyl]acetic acid;hydrochlorideIC505480.0 [1]
N-(1-Benzyl-4-piperidinyl)-1,3-benzodioxole-5-carboxamideKi42000.0 [1]
N,N-Dimethyl-2-[(1,7,7-trimethyl-2-phenyl-2-bicyclo[2.2.1]heptanyl)oxy]ethanamineIC5039000.0 [1]
1-[2-[Tris(4-methoxyphenyl)methoxy]ethyl]-3,6-dihydro-2H-pyridine-5-carboxylic acidIC502660000.0 [1]
(3S)-8-Benzhydrylidene-1,2,3,4,6,7,9,9a-octahydroquinolizine-3-carboxylic acidIC50335000.0 [1]
(3R,8R)-8-Benzhydryl-2,3,4,6,7,8,9,9a-octahydro-1H-quinolizine-3-carboxylic acidIC502900000.0 [1]
(3S,8R)-8-Benzhydryl-2,3,4,6,7,8,9,9a-octahydro-1H-quinolizine-3-carboxylic acidIC50809000.0 [1]
(3R)-8-Benzhydrylidene-1,2,3,4,6,7,9,9a-octahydroquinolizine-3-carboxylic acidIC50436000.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Betaine transporter Inhibitors (IC50, Ki)." AAT Bioquest, Inc.20 Nov2024https://www.aatbio.com/data-sets/betaine-transporter-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024November 20). Quest Database™ Betaine transporter Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/betaine-transporter-inhibitors-ic50-ki.
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