Beta-hexosaminidase subunit alpha Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Pyrimethamine	IC50	8500.0 [1]
	3AR,5R,6S,7R,7AR-5-Hydroxymethyl-2-methyl-5,6,7,7A-tetrahydro-3AH-pyrano[3,2-D]thiazole-6,7-diol	Ki	270.0 [1]
	6-Ethyl-5-phenylpyrimidine-2,4-diamine	IC50	27000.0 [1]
	2-[2-[2-(1,3-Dioxobenzo[de]isoquinolin-2-yl)ethylamino]ethyl]benzo[de]isoquinoline-1,3-dione	IC50	6000.0 [1]
	(3R,4S,5R,6R)-5-(Hydroxymethyl)-6-pentylpiperidine-3,4-diol	IC50	160000.0 [1]
	(5R,6R,7S,8S)-5-(Hydroxymethyl)-2-[2-(4-phenylphenyl)ethyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-6,7,8-triol	Ki	163000.0 [1]
	N-[(3S,4S,5R,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-1-(octylcarbamothioyl)piperidin-3-yl]acetamide	IC50	350000.0 [1]
	N-[(6S,7S,8R,8As)-7,8-dihydroxy-3-phenylimino-1,5,6,7,8,8a-hexahydro-[1,3]thiazolo[3,4-a]pyridin-6-yl]acetamide	IC50	100000.0 [1]
	N-[(6S,7S,8R,8As)-7,8-dihydroxy-3-octylimino-1,5,6,7,8,8a-hexahydro-[1,3]thiazolo[3,4-a]pyridin-6-yl]acetamide	IC50	100000.0 [1]
	N-[(2S,3S,4R,5R,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-2-(4-phenylbutoxymethyl)piperidin-3-yl]acetamide	IC50	100.0 [1]

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References

This online tool may be cited as follows

MLA	"Quest Database™ Beta-hexosaminidase subunit alpha Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 30 Mar. 2025, https://www.aatbio.com/data-sets/beta-hexosaminidase-subunit-alpha-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, March 30). Quest Database™ Beta-hexosaminidase subunit alpha Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/beta-hexosaminidase-subunit-alpha-inhibitors-ic50-ki.
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