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Beta-glucuronidase Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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D-Glucaro-1,4-lactoneIC5048300.0 [1]
Methyl 2-amino-5-[(3-chloro-4-methylphenyl)carbamoyl]-4-methylthiophene-3-carboxylateIC501624.0 [1], 1688.9 [2]
2-Phenylquinazolin-4-olIC50177000.0 [1]
2-(4-Methoxyphenyl)-1H-quinazolin-4-oneIC501100.0 [1]
2-(4-Nitrophenyl)quinazolin-4-olIC5020100.0 [1]
2-[4-(Dimethylamino)phenyl]-4(3H)-quinazolinoneIC505500.0 [1]
2-(4-Chlorophenyl)quinazolin-4-olIC5039800.0 [1]
4(1H)-Quinazolinone, 2-(2-hydroxyphenyl)-IC5010000.0 [1]
2-(4-Hydroxyphenyl)-3h-Quinazolin-4-OneIC5022200.0 [1]
2-(3,4-Dimethoxyphenyl)quinazolin-4-olIC50600.0 [1]
2-(3-Hydroxyphenyl)quinazolin-4(3H)-oneIC50198200.0 [1]
2-(3,4-Dihydroxyphenyl)quinazoline-4(3H)-oneIC502100.0 [1]
2-(3-Nitrophenyl)quinazolin-4(3H)-oneIC5050400.0 [1]
2-(2-Nitrophenyl)quinazolin-4(3h)-oneIC501500.0 [1]
2-(3-Hydroxy-4-methoxyphenyl)quinazoline-4(3H)-oneIC502800.0 [1]
2-(2-Chlorophenyl)quinazolin-4-olIC501800.0 [1]
2-(4-Methylphenyl)quinazolin-4(3H)-oneIC50172700.0 [1]
2-(4-Ethoxyphenyl)quinazoline-4(3H)-oneIC502100.0 [1]
2-(2-Ethoxyphenyl)quinazoline-4(3H)-oneIC50700.0 [1]
2-(2,5-Dihydroxyphenyl)-4(3H)-quinazolinoneIC503200.0 [1]
2-(2-Hydroxy-5-methoxyphenyl)quinazoline-4(3H)-oneIC501800.0 [1]
2-(3,4,5-Trimethoxyphenyl)quinazoline-4(3H)-oneIC50120500.0 [1]
2-[5-[4-(5,6-Dimethyl-1H-benzimidazol-2-yl)phenyl]-1,3,4-oxadiazol-2-yl]phenolIC502140.0 [1]
2-(2,6-Dichlorophenyl)-3H-quinazolin-4-oneIC5037700.0 [1]
2-(3-Ethoxy-4-hydroxyphenyl)quinazoline-4(3H)-oneIC501170.0 [1]
2-(2-Hydroxy-3-methoxyphenyl)quinazoline-4(3H)-oneIC5030900.0 [1]
2-(6-Bromo-2-hydroxyphenyl)quinazoline-4(3H)-oneIC5044000.0 [1]
(E)-4,4,4-Triethoxy-1-[3-methyl-4-phenyl-5-[(E)-4,4,4-triethoxybut-2-enoyl]thieno[2,3-b]thiophen-2-yl]but-2-en-1-oneIC50900.0 [1]
2-(3,4-Dimethoxyphenyl)-5-[4-(5,6-dimethyl-1H-benzimidazol-2-yl)phenyl]-1,3,4-oxadiazoleIC5046140.0 [1]
3-[5-[4-(5,6-Dimethyl-1H-benzimidazol-2-yl)phenyl]-1,3,4-oxadiazol-2-yl]phenolIC508140.0 [1]
2-[4-(5,6-Dimethyl-1H-benzimidazol-2-yl)phenyl]-5-(3-nitrophenyl)-1,3,4-oxadiazoleIC5011140.0 [1]
2-(2-Chlorophenyl)-5-[4-(5,6-dimethyl-1H-benzimidazol-2-yl)phenyl]-1,3,4-oxadiazoleIC5015140.0 [1]
2-[4-(5,6-Dimethyl-1H-benzimidazol-2-yl)phenyl]-5-(2-fluorophenyl)-1,3,4-oxadiazoleIC5019160.0 [1]
2-[4-(5,6-Dimethyl-1H-benzimidazol-2-yl)phenyl]-5-(4-fluorophenyl)-1,3,4-oxadiazoleIC5013140.0 [1]
2-[4-(5,6-Dimethyl-1H-benzimidazol-2-yl)phenyl]-5-pyridin-2-yl-1,3,4-oxadiazoleIC504120.0 [1]
2-[4-(5,6-Dimethyl-1H-benzimidazol-2-yl)phenyl]-5-(3-fluorophenyl)-1,3,4-oxadiazoleIC5016120.0 [1]
2-[4-(5,6-Dimethyl-1H-benzimidazol-2-yl)phenyl]-5-(4-nitrophenyl)-1,3,4-oxadiazoleIC5030140.0 [1]
2-(4-Chlorophenyl)-5-[4-(5,6-dimethyl-1H-benzimidazol-2-yl)phenyl]-1,3,4-oxadiazoleIC5032140.0 [1]
2-[4-(5,6-Dimethyl-1H-benzimidazol-2-yl)phenyl]-5-pyridin-4-yl-1,3,4-oxadiazoleIC5040140.0 [1]
2-(3-Chlorophenyl)-5-[4-(5,6-dimethyl-1H-benzimidazol-2-yl)phenyl]-1,3,4-oxadiazoleIC5031140.0 [1]
2-[4-(5,6-Dimethyl-1H-benzimidazol-2-yl)phenyl]-5-pyridin-3-yl-1,3,4-oxadiazoleIC5020140.0 [1]
8-Fluoro-N-[(E)-(3-hydroxy-4-methoxyphenyl)methylideneamino]-4-oxo-1H-quinoline-3-carboxamideIC5018000.0 [1]
8-Fluoro-4-oxo-N-[(E)-thiophen-2-ylmethylideneamino]-1H-quinoline-3-carboxamideIC5022300.0 [1]
8-Fluoro-N-[(E)-(2-methylphenyl)methylideneamino]-4-oxo-1H-quinoline-3-carboxamideIC5038500.0 [1]
8-Fluoro-N-[(E)-(3-methylphenyl)methylideneamino]-4-oxo-1H-quinoline-3-carboxamideIC5051000.0 [1]
8-Fluoro-N-[(E)-(3-methoxyphenyl)methylideneamino]-4-oxo-1H-quinoline-3-carboxamideIC5080100.0 [1]
8-Fluoro-N-[(E)-(4-methoxyphenyl)methylideneamino]-4-oxo-1H-quinoline-3-carboxamideIC5069400.0 [1]
8-Fluoro-N-[(E)-(2-nitrophenyl)methylideneamino]-4-oxo-1H-quinoline-3-carboxamideIC5016600.0 [1]
8-Fluoro-N-[(E)-(3-nitrophenyl)methylideneamino]-4-oxo-1H-quinoline-3-carboxamideIC5078900.0 [1]
8-Fluoro-N-[(E)-(4-nitrophenyl)methylideneamino]-4-oxo-1H-quinoline-3-carboxamideIC5044100.0 [1]
8-Fluoro-4-oxo-N-[(E)-pyridin-2-ylmethylideneamino]-1H-quinoline-3-carboxamideIC5019400.0 [1]
8-Fluoro-4-oxo-N-[(E)-pyridin-3-ylmethylideneamino]-1H-quinoline-3-carboxamideIC5068380.0 [1]
8-Fluoro-4-oxo-N-[(E)-pyridin-4-ylmethylideneamino]-1H-quinoline-3-carboxamideIC5049380.0 [1]
N-[(E)-(3-Chlorophenyl)methylideneamino]-8-fluoro-4-oxo-1H-quinoline-3-carboxamideIC5042250.0 [1]
8-Fluoro-N-[(E)-furan-2-ylmethylideneamino]-4-oxo-1H-quinoline-3-carboxamideIC5038500.0 [1]
8-Fluoro-N-[(E)-(3-hydroxyphenyl)methylideneamino]-4-oxo-1H-quinoline-3-carboxamideIC5018100.0 [1]
8-Fluoro-N-[(E)-(4-methylphenyl)methylideneamino]-4-oxo-1H-quinoline-3-carboxamideIC5046140.0 [1]
8-Fluoro-N-[(E)-(4-fluorophenyl)methylideneamino]-4-oxo-1H-quinoline-3-carboxamideIC5026300.0 [1]
8-Fluoro-N-[(E)-(2-fluorophenyl)methylideneamino]-4-oxo-1H-quinoline-3-carboxamideIC509200.0 [1]
N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-8-fluoro-4-oxo-1H-quinoline-3-carboxamideIC5046100.0 [1]
N-[(E)-(2-Chlorophenyl)methylideneamino]-8-fluoro-4-oxo-1H-quinoline-3-carboxamideIC5018400.0 [1]
N-[(E)-(4-Chlorophenyl)methylideneamino]-8-fluoro-4-oxo-1H-quinoline-3-carboxamideIC5024200.0 [1]
8-Fluoro-N-[(E)-(3-fluorophenyl)methylideneamino]-4-oxo-1H-quinoline-3-carboxamideIC5037010.0 [1]
2-(2,4-Dichlorophenyl)quinazolin-4-olIC5061030.0 [1]
4-[5-[4-(5,6-Dimethyl-1H-benzimidazol-2-yl)phenyl]-1,3,4-oxadiazol-2-yl]phenolIC503140.0 [1]
8-Fluoro-N-[(E)-(4-hydroxyphenyl)methylideneamino]-4-oxo-1H-quinoline-3-carboxamideIC509600.0 [1]
8-Fluoro-N-[(E)-(2-hydroxyphenyl)methylideneamino]-4-oxo-1H-quinoline-3-carboxamideIC506700.0 [1]
8-Fluoro-N-[(E)-(2-hydroxy-4-methoxyphenyl)methylideneamino]-4-oxo-1H-quinoline-3-carboxamideIC509600.0 [1]
8-Fluoro-N-[(E)-(2-hydroxy-5-methoxyphenyl)methylideneamino]-4-oxo-1H-quinoline-3-carboxamideIC508300.0 [1]
N-[(E)-(2,5-Dihydroxyphenyl)methylideneamino]-8-fluoro-4-oxo-1H-quinoline-3-carboxamideIC505010.0 [1]
N-[(E)-(2,3-Dihydroxyphenyl)methylideneamino]-8-fluoro-4-oxo-1H-quinoline-3-carboxamideIC502600.0 [1]
N-[(E)-(2,4-Dihydroxyphenyl)methylideneamino]-8-fluoro-4-oxo-1H-quinoline-3-carboxamideIC503100.0 [1]
N-[(E)-(3,4-Dihydroxyphenyl)methylideneamino]-8-fluoro-4-oxo-1H-quinoline-3-carboxamideIC502110.0 [1]
N-[(E)-(2,4-Dichlorophenyl)methylideneamino]-3-[[5-[[(E)-(2,4-dichlorophenyl)methylideneamino]carbamoyl]-1H-indol-3-yl]-(4-methylphenyl)methyl]-1H-indole-5-carboxamideIC501100.0 [1]
N-[(E)-(3,4-Dihydroxyphenyl)methylideneamino]-3-[[5-[[(E)-(3,4-dihydroxyphenyl)methylideneamino]carbamoyl]-1H-indol-3-yl]-(4-methylphenyl)methyl]-1H-indole-5-carboxamideIC50300.0 [1]
N-[(E)-(3-Methylphenyl)methylideneamino]-3-[(4-methylphenyl)-[5-[[(E)-(3-methylphenyl)methylideneamino]carbamoyl]-1H-indol-3-yl]methyl]-1H-indole-5-carboxamideIC5033500.0 [1]
3-[(4-Methylphenyl)-[5-[[(E)-[(E)-3-phenylprop-2-enylidene]amino]carbamoyl]-1H-indol-3-yl]methyl]-N-[(E)-[(E)-3-phenylprop-2-enylidene]amino]-1H-indole-5-carboxamideIC502980.0 [1]
3-[(4-Methylphenyl)-[5-[[(E)-pyridin-4-ylmethylideneamino]carbamoyl]-1H-indol-3-yl]methyl]-N-[(E)-pyridin-4-ylmethylideneamino]-1H-indole-5-carboxamideIC5023400.0 [1]
N-[(E)-(2-Chlorophenyl)methylideneamino]-3-[[5-[[(E)-(2-chlorophenyl)methylideneamino]carbamoyl]-1H-indol-3-yl]-(4-methylphenyl)methyl]-1H-indole-5-carboxamideIC502800.0 [1]
N-[(E)-(2,4-Dihydroxyphenyl)methylideneamino]-3-[[5-[[(E)-(2,4-dihydroxyphenyl)methylideneamino]carbamoyl]-1H-indol-3-yl]-(4-methylphenyl)methyl]-1H-indole-5-carboxamideIC50300.0 [1]
N-[(E)-Benzylideneamino]-3-[[5-[[(E)-benzylideneamino]carbamoyl]-1H-indol-3-yl]-(4-methylphenyl)methyl]-1H-indole-5-carboxamideIC5042750.0 [1]
N-[(E)-(3-Fluorophenyl)methylideneamino]-3-[[5-[[(E)-(3-fluorophenyl)methylideneamino]carbamoyl]-1H-indol-3-yl]-(4-methylphenyl)methyl]-1H-indole-5-carboxamideIC502200.0 [1]
N-[(E)-(2-Hydroxy-4-methoxyphenyl)methylideneamino]-3-[[5-[[(E)-(2-hydroxy-4-methoxyphenyl)methylideneamino]carbamoyl]-1H-indol-3-yl]-(4-methylphenyl)methyl]-1H-indole-5-carboxamideIC503448.0 [1]
N-[(E)-(2,3-Dihydroxyphenyl)methylideneamino]-3-[[5-[[(E)-(2,3-dihydroxyphenyl)methylideneamino]carbamoyl]-1H-indol-3-yl]-(4-methylphenyl)methyl]-1H-indole-5-carboxamideIC50100.0 [1]
N-[(E)-(3-Hydroxy-4-methoxyphenyl)methylideneamino]-3-[[5-[[(E)-(3-hydroxy-4-methoxyphenyl)methylideneamino]carbamoyl]-1H-indol-3-yl]-(4-methylphenyl)methyl]-1H-indole-5-carboxamideIC502670.0 [1]
N-[(E)-(2-Fluorophenyl)methylideneamino]-3-[[5-[[(E)-(2-fluorophenyl)methylideneamino]carbamoyl]-1H-indol-3-yl]-(4-methylphenyl)methyl]-1H-indole-5-carboxamideIC501200.0 [1]
3-[(4-Methylphenyl)-[5-[[(E)-(2,4,5-trihydroxyphenyl)methylideneamino]carbamoyl]-1H-indol-3-yl]methyl]-N-[(E)-(2,4,5-trihydroxyphenyl)methylideneamino]-1H-indole-5-carboxamideIC50100.0 [1]
N-[(E)-(3-Hydroxy-2-iodo-4-methoxyphenyl)methylideneamino]-3-[[5-[[(E)-(3-hydroxy-2-iodo-4-methoxyphenyl)methylideneamino]carbamoyl]-1H-indol-3-yl]-(4-methylphenyl)methyl]-1H-indole-5-carboxamideIC5043500.0 [1]
N-[(E)-(3-Hydroxyphenyl)methylideneamino]-3-[[5-[[(E)-(3-hydroxyphenyl)methylideneamino]carbamoyl]-1H-indol-3-yl]-(4-methylphenyl)methyl]-1H-indole-5-carboxamideIC505874.0 [1]
3-[(4-Methylphenyl)-[5-[[(E)-(2-nitrophenyl)methylideneamino]carbamoyl]-1H-indol-3-yl]methyl]-N-[(E)-(2-nitrophenyl)methylideneamino]-1H-indole-5-carboxamideIC5048500.0 [1]
N-[(E)-(2-Methylphenyl)methylideneamino]-3-[(4-methylphenyl)-[5-[[(E)-(2-methylphenyl)methylideneamino]carbamoyl]-1H-indol-3-yl]methyl]-1H-indole-5-carboxamideIC5022200.0 [1]
N-[(E)-(4-Chlorophenyl)methylideneamino]-3-[[5-[[(E)-(4-chlorophenyl)methylideneamino]carbamoyl]-1H-indol-3-yl]-(4-methylphenyl)methyl]-1H-indole-5-carboxamideIC505800.0 [1]
3-[(4-Methylphenyl)-[5-[[(E)-pyridin-2-ylmethylideneamino]carbamoyl]-1H-indol-3-yl]methyl]-N-[(E)-pyridin-2-ylmethylideneamino]-1H-indole-5-carboxamideIC5013100.0 [1]
N-[(E)-(4-Methylphenyl)methylideneamino]-3-[(4-methylphenyl)-[5-[[(E)-(4-methylphenyl)methylideneamino]carbamoyl]-1H-indol-3-yl]methyl]-1H-indole-5-carboxamideIC5012500.0 [1]
3-[(4-Methylphenyl)-[5-[[(E)-(3-nitrophenyl)methylideneamino]carbamoyl]-1H-indol-3-yl]methyl]-N-[(E)-(3-nitrophenyl)methylideneamino]-1H-indole-5-carboxamideIC507571.0 [1]
N-[(E)-(2,5-Dihydroxyphenyl)methylideneamino]-3-[[5-[[(E)-(2,5-dihydroxyphenyl)methylideneamino]carbamoyl]-1H-indol-3-yl]-(4-methylphenyl)methyl]-1H-indole-5-carboxamideIC501140.0 [1]
N-[(E)-(2-Hydroxy-5-methoxyphenyl)methylideneamino]-3-[[5-[[(E)-(2-hydroxy-5-methoxyphenyl)methylideneamino]carbamoyl]-1H-indol-3-yl]-(4-methylphenyl)methyl]-1H-indole-5-carboxamideIC502100.0 [1]
3-[(4-Methylphenyl)-[5-[[(E)-pyridin-3-ylmethylideneamino]carbamoyl]-1H-indol-3-yl]methyl]-N-[(E)-pyridin-3-ylmethylideneamino]-1H-indole-5-carboxamideIC5032900.0 [1]
N-[(E)-(3-Chlorophenyl)methylideneamino]-3-[[5-[[(E)-(3-chlorophenyl)methylideneamino]carbamoyl]-1H-indol-3-yl]-(4-methylphenyl)methyl]-1H-indole-5-carboxamideIC506900.0 [1]
N-[(E)-(4-Methoxyphenyl)methylideneamino]-3-[[5-[[(E)-(4-methoxyphenyl)methylideneamino]carbamoyl]-1H-indol-3-yl]-(4-methylphenyl)methyl]-1H-indole-5-carboxamideIC5032800.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Beta-glucuronidase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/beta-glucuronidase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Beta-glucuronidase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/beta-glucuronidase-inhibitors-ic50-ki.
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