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Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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N-(2-Cyclobutyltriazol-4-yl)-2-[2-(3-methoxyphenyl)acetyl]-1,3-dihydroisoindole-5-sulfonamideIC50100.0 [1], 204.17 [2]
2-[2-(3-Methoxyphenyl)acetyl]-N-[2-(oxan-3-yl)triazol-4-yl]-1,3-dihydroisoindole-5-sulfonamideIC5079.43 [1], 794.33 [2]
N-[2-(3,3-Difluorocyclobutyl)triazol-4-yl]-2-[2-(3-methoxyphenyl)acetyl]-1,3-dihydroisoindole-5-sulfonamideIC5063.1 [1], 389.05 [2]
N-[5-[(2,4-Difluorophenyl)sulfamoyl]-1-(2-phenylethyl)-2,3-dihydroindol-7-yl]acetamideIC5030000.0 [1]
N-[2-(3-Fluorophenyl)ethyl]-2-[2-(3-methoxyphenyl)acetyl]-1,3-dihydroisoindole-5-sulfonamideIC50630.96 [1]
N-[2-(3-Fluorophenyl)ethyl]-2-[2-(3-methoxyphenyl)acetyl]-N-methyl-1,3-dihydroisoindole-5-sulfonamideIC502511.89 [1]
2-[2-(3-Methoxyphenyl)acetyl]-N-(2-methyltriazol-4-yl)-1,3-dihydroisoindole-5-sulfonamideIC503981.07 [1]
2-[2-(3-Methoxyphenyl)acetyl]-N-(2-phenyltriazol-4-yl)-1,3-dihydroisoindole-5-sulfonamideIC506.31 [1]
N-[2-(4-Fluorophenyl)triazol-4-yl]-2-[2-(3-methoxyphenyl)acetyl]-1,3-dihydroisoindole-5-sulfonamideIC506.31 [1]
2-[2-(3-Methoxyphenyl)acetyl]-N-(2-propan-2-yltriazol-4-yl)-1,3-dihydroisoindole-5-sulfonamideIC50630.96 [1]
2-[2-(3-Methoxyphenyl)acetyl]-N-[2-(oxetan-3-yl)triazol-4-yl]-1,3-dihydroisoindole-5-sulfonamideIC50398.11 [1]
(3S)-N-(2,4-Difluorophenyl)-3-ethyl-3-methyl-2,5-dioxo-1,4-dihydro-1,4-benzodiazepine-7-sulfonamideIC5050.12 [1]
(3S)-N-[4-(Difluoromethoxy)phenyl]-3-ethyl-3-methyl-2,5-dioxo-1,4-dihydro-1,4-benzodiazepine-7-sulfonamideIC50125.89 [1]
3-Ethyl-3-methyl-2,5-dioxo-N-phenyl-1,4-dihydro-1,4-benzodiazepine-7-sulfonamideIC502511.89 [1]
N-(4-Chlorophenyl)-3-ethyl-3-methyl-2,5-dioxo-1,4-dihydro-1,4-benzodiazepine-7-sulfonamideIC50398.11 [1]
[(3R)-1-[8-[1-(4-Chloropyrazol-1-yl)ethyl]-7H-purin-2-yl]piperidin-3-yl]-pyrrolidin-1-ylmethanoneIC5050000.0 [1]
[(3R)-1-[2-[(1S)-1-(4-Chloropyrazol-1-yl)ethyl]-1H-imidazo[4,5-b]pyridin-5-yl]piperidin-3-yl]-pyrrolidin-1-ylmethanoneIC5050000.0 [1]
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References

This online tool may be cited as follows

MLA

"Quest Database™ Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Dec. 2024, https://www.aatbio.com/data-sets/beta-1-4-mannosyl-glycoprotein-4-beta-n-acetylglucosaminyltransferase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, December 21). Quest Database™ Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/beta-1-4-mannosyl-glycoprotein-4-beta-n-acetylglucosaminyltransferase-inhibitors-ic50-ki.
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