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Bcl-xL/Bcl-2-like protein 11 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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Abt-737IC502.0 [1]
NavitoclaxIC504.3 [1]
Marinopyrrole AIC5016400.0 [1]
(4-Chloro-2-hydroxyphenyl)-[4,5-dichloro-1-[4,5-dichloro-2-(2-hydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]methanoneIC509200.0 [1]
[4,5-Dichloro-3-[2,3-dichloro-5-(5-fluoro-2-hydroxybenzoyl)pyrrol-1-yl]-1H-pyrrol-2-yl]-(2-hydroxyphenyl)methanoneIC5013300.0 [1]
2-[4-[1-[2-[4-(Carboxymethylsulfanyl)-2-hydroxybenzoyl]-4,5-dichloro-1H-pyrrol-3-yl]-4,5-dichloropyrrole-2-carbonyl]-3-hydroxyphenyl]sulfanylacetic acidIC50100000.0 [1]
[4,5-Dichloro-3-[2,3-dichloro-5-(2-fluoro-6-hydroxybenzoyl)pyrrol-1-yl]-1H-pyrrol-2-yl]-(2-hydroxyphenyl)methanoneIC5043700.0 [1]
(4-Chloro-2-methoxyphenyl)-[4,5-dichloro-1-[4,5-dichloro-2-(2-methoxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]methanoneIC509500.0 [1]
[4,5-Dichloro-1-[4,5-dichloro-2-[2-hydroxy-4-(1-phenyltriazol-4-yl)benzoyl]-1H-pyrrol-3-yl]pyrrol-2-yl]-[2-hydroxy-4-(1-phenyltriazol-4-yl)phenyl]methanoneIC50800.0 [1]
[4-(1-Cyclohexyltriazol-4-yl)-2-hydroxyphenyl]-[4,5-dichloro-1-[4,5-dichloro-2-[4-(1-cyclohexyltriazol-4-yl)-2-hydroxybenzoyl]-1H-pyrrol-3-yl]pyrrol-2-yl]methanoneIC503800.0 [1]
[4,5-Dichloro-1-[4,5-dichloro-2-(4-ethenyl-2-hydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]-(4-ethenyl-2-hydroxyphenyl)methanoneIC503500.0 [1]
[4,5-Dichloro-1-[4,5-dichloro-2-(4-ethynyl-2-hydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]-(4-ethynyl-2-hydroxyphenyl)methanoneIC505600.0 [1]
Ethyl 2-[4-[2-chloro-4-[4,5-dichloro-1-[4,5-dichloro-2-[5-chloro-4-[1-(2-ethoxy-2-oxoethyl)triazol-4-yl]-2-hydroxybenzoyl]-1H-pyrrol-3-yl]pyrrole-2-carbonyl]-5-hydroxyphenyl]triazol-1-yl]acetateIC50100000.0 [1]
[1-[2-[4-(1-Benzyltriazol-4-yl)-2-hydroxybenzoyl]-4,5-dichloro-1H-pyrrol-3-yl]-4,5-dichloropyrrol-2-yl]-[4-(1-benzyltriazol-4-yl)-2-hydroxyphenyl]methanoneIC501600.0 [1]
2-[4-[4-[1-[2-[4-[1-(Carboxymethyl)triazol-4-yl]-5-chloro-2-hydroxybenzoyl]-4,5-dichloro-1H-pyrrol-3-yl]-4,5-dichloropyrrole-2-carbonyl]-2-chloro-5-hydroxyphenyl]triazol-1-yl]acetic acidIC5050000.0 [1]
Ethyl 2-[4-[4-[4,5-dichloro-1-[4,5-dichloro-2-[4-[1-(2-ethoxy-2-oxoethyl)triazol-4-yl]-2-hydroxybenzoyl]-1H-pyrrol-3-yl]pyrrole-2-carbonyl]-3-hydroxyphenyl]triazol-1-yl]acetateIC50100000.0 [1]
2-[4-[4-[1-[2-[4-[1-(Carboxymethyl)triazol-4-yl]-2-hydroxybenzoyl]-4,5-dichloro-1H-pyrrol-3-yl]-4,5-dichloropyrrole-2-carbonyl]-3-hydroxyphenyl]triazol-1-yl]acetic acidIC5050000.0 [1]
[4,5-Dichloro-1-[4,5-dichloro-2-(4-ethyl-2-hydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]-(4-ethyl-2-hydroxyphenyl)methanoneIC503900.0 [1]
[4-[4,5-Dichloro-3-[2,3-dichloro-5-(2-hydroxybenzoyl)pyrrol-1-yl]-1H-pyrrole-2-carbonyl]-3-hydroxyphenyl] trifluoromethanesulfonateIC502100.0 [1]
Ethyl 2-[4-[4,5-dichloro-1-[4,5-dichloro-2-[4-(2-ethoxy-2-oxoethyl)sulfanyl-2-hydroxybenzoyl]-1H-pyrrol-3-yl]pyrrole-2-carbonyl]-3-hydroxyphenyl]sulfanylacetateIC501200.0 [1]
[1-[2-(4-Benzylsulfanyl-2-hydroxybenzoyl)-4,5-dichloro-1H-pyrrol-3-yl]-4,5-dichloropyrrol-2-yl]-(4-benzylsulfanyl-2-hydroxyphenyl)methanoneIC50600.0 [1]
[4,5-Dichloro-1-[4,5-dichloro-2-[2-hydroxy-4-[(4-methoxyphenyl)methylsulfanyl]benzoyl]-1H-pyrrol-3-yl]pyrrol-2-yl]-[2-hydroxy-4-[(4-methoxyphenyl)methylsulfanyl]phenyl]methanoneIC50600.0 [1]
[4-[4,5-Dichloro-1-[4,5-dichloro-2-(2-hydroxy-4-phosphonobenzoyl)-1H-pyrrol-3-yl]pyrrole-2-carbonyl]-3-hydroxyphenyl]phosphonic acidIC5027300.0 [1]
Tert-butyl 2-[4-[2-chloro-4-[4,5-dichloro-1-[4,5-dichloro-2-[5-chloro-2-hydroxy-4-[1-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]triazol-4-yl]benzoyl]-1H-pyrrol-3-yl]pyrrole-2-carbonyl]-5-hydroxyphenyl]triazol-1-yl]acetateIC5014000.0 [1]
[4,5-Dichloro-1-[4,5-dichloro-2-[2-hydroxy-4-(1-octyltriazol-4-yl)benzoyl]-1H-pyrrol-3-yl]pyrrol-2-yl]-[4-(1-heptyltriazol-4-yl)-2-hydroxyphenyl]methanoneIC50500.0 [1]
Tert-butyl 2-[4-[4-[4,5-dichloro-1-[4,5-dichloro-2-[2-hydroxy-4-[1-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]triazol-4-yl]benzoyl]-1H-pyrrol-3-yl]pyrrole-2-carbonyl]-3-hydroxyphenyl]triazol-1-yl]acetateIC508100.0 [1]
[4,5-Dichloro-1-[4,5-dichloro-2-(2-methoxybenzoyl)-1-methylpyrrol-3-yl]pyrrol-2-yl]-(2-methoxyphenyl)methanoneIC5064900.0 [1]
[4,5-Dichloro-1-[4,5-dichloro-2-(2-hydroxybenzoyl)-1-methylpyrrol-3-yl]pyrrol-2-yl]-(2-hydroxyphenyl)methanoneIC507900.0 [1]
Marinopyrrole DIC5018300.0 [1]
7-(2-Ethoxyquinolin-3-yl)-2-methoxy-3-(2-methoxy-5-propan-2-ylquinolin-7-yl)-5-propan-2-ylquinolineIC5047000.0 [1]
2-Methoxy-3-[2-methoxy-5-(2-methylpropyl)quinolin-7-yl]-5-propan-2-ylquinolineIC5029000.0 [1]
3-(5-Butan-2-yl-2-methoxyquinolin-7-yl)-2-methoxy-7-(2-methoxy-5-propan-2-ylquinolin-3-yl)-5-(2-methylpropyl)quinolineIC5092500.0 [1]
[4,5-Dichloro-1-[4,5-dichloro-2-(2-hydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]-(4-fluoro-2-hydroxyphenyl)methanoneIC5021300.0 [1]
(3-Chloro-2-hydroxyphenyl)-[4,5-dichloro-1-[4,5-dichloro-2-(2-hydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]methanoneIC5010100.0 [1]
[4,5-Dichloro-1-[4,5-dichloro-2-[2-hydroxy-4-(trifluoromethyl)benzoyl]-1H-pyrrol-3-yl]pyrrol-2-yl]-[2-hydroxy-4-(trifluoromethyl)phenyl]methanoneIC509700.0 [1]
(5-Chloro-2,4-dihydroxyphenyl)-[4,5-dichloro-1-[4,5-dichloro-2-(5-chloro-2,4-dihydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]methanoneIC5050000.0 [1]
[4,5-Dichloro-1-[4,5-dichloro-2-(2,4-dihydroxybenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]-(2,4-dihydroxyphenyl)methanoneIC5050000.0 [1]
(5-Chloro-2-hydroxy-4-methylphenyl)-[4,5-dichloro-1-[4,5-dichloro-2-(5-chloro-2-hydroxy-4-methylbenzoyl)-1H-pyrrol-3-yl]pyrrol-2-yl]methanoneIC502500.0 [1]
Items per page: 1 - 10 of 38
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References

This online tool may be cited as follows

MLA

"Quest Database™ Bcl-xL/Bcl-2-like protein 11 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/bcl-xl-bcl-2-like-protein-11-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 22). Quest Database™ Bcl-xL/Bcl-2-like protein 11 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/bcl-xl-bcl-2-like-protein-11-inhibitors-ic50-ki.
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