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Bcl-xL/BAK Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
Abt-737IC5010.0 [1]
Abt-737Ki1.0 [1]
Meiogynin AKi9000.0 [1], 40000.0 [2]
DesmethoxyyangoninKi23000.0 [1]
Alexidine dihydrochlorideIC5018300.0 [1]
(2R,4Ar,5S,8aR)-5-[(E)-2-(4-carboxycyclohexyl)prop-1-enyl]-7-methyl-2-[(2S)-6-methylhept-5-en-2-yl]-2,5,8,8a-tetrahydro-1H-naphthalene-4a-carboxylic acidKi2600.0 [1]
(2R,4Ar,5S,8aR)-5-[(E)-2-(4-carboxyphenyl)prop-1-enyl]-7-methyl-2-[(2R)-6-methylhept-5-en-2-yl]-2,5,8,8a-tetrahydro-1H-naphthalene-4a-carboxylic acidKi4600.0 [1]
(2R,4Ar,5S,8aR)-5-[(E)-2-(4-carboxyphenyl)prop-1-enyl]-7-methyl-2-[(2S)-6-methylhept-5-en-2-yl]-2,5,8,8a-tetrahydro-1H-naphthalene-4a-carboxylic acidKi7500.0 [1]
2,5-Dihydroxy-3-methoxy-6-[(1S,6S)-4-(4-methylpent-3-enyl)-6-phenylcyclohex-3-ene-1-carbonyl]cyclohexa-2,5-diene-1,4-dioneKi23000.0 [1]
2,5-Dihydroxy-3-methoxy-6-[(1R,6R)-4-(4-methylpent-3-enyl)-6-phenylcyclohex-3-ene-1-carbonyl]cyclohexa-2,5-diene-1,4-dioneKi4800.0 [1]
1-[4-(4-Methylpent-3-enyl)-6-phenylcyclohex-3-en-1-yl]ethanoneKi23000.0 [1]
4-(4-Methylpent-3-enyl)-6-phenylcyclohex-3-ene-1-carboxylic acidKi23000.0 [1]
2,5-Dihydroxy-3-methoxy-6-[4-(4-methylpent-3-enyl)-6-phenylcyclohex-3-ene-1-carbonyl]cyclohexa-2,5-diene-1,4-dioneKi17500.0 [1]
(2R)-6,7-Dimethoxy-2-phenyl-2,3-dihydrochromene-4,5,8-trioneKi23000.0 [1]
1-[3-(4-Methylpent-3-enyl)-6-phenylcyclohex-3-en-1-yl]ethanoneKi23000.0 [1]
(2R)-5,8-Dihydroxy-6,7-dimethoxy-2-phenyl-2,3-dihydrochromen-4-oneKi23000.0 [1]
(2S,4As,5R,8aS)-5-[(E)-2-(4-carboxycyclohexyl)prop-1-enyl]-7-methyl-2-[(2S)-6-methylhept-5-en-2-yl]-2,5,8,8a-tetrahydro-1H-naphthalene-4a-carboxylic acidKi100000.0 [1]
(2R,4Ar,5S,8aR)-5-[(E)-2-(4-carboxycyclohexyl)prop-1-enyl]-7-methyl-2-[(2R)-6-methylhept-5-en-2-yl]-2,5,8,8a-tetrahydro-1H-naphthalene-4a-carboxylic acidKi2300.0 [1]
7-(2-Ethoxyquinolin-3-yl)-2-methoxy-3-(2-methoxy-5-propan-2-ylquinolin-7-yl)-5-propan-2-ylquinolineIC5074000.0 [1]
2-Methoxy-3-[2-methoxy-5-(2-methylpropyl)quinolin-7-yl]-5-propan-2-ylquinolineIC501000000.0 [1]
3-(5-Butan-2-yl-2-methoxyquinolin-7-yl)-2-methoxy-7-(2-methoxy-5-propan-2-ylquinolin-3-yl)-5-(2-methylpropyl)quinolineIC5025000.0 [1]
1-[N'-[6-[[Amino-[[N'-[(2S)-2-ethylhexyl]carbamimidoyl]amino]methylidene]amino]hexyl]carbamimidoyl]-2-[(2S)-2-ethylhexyl]guanidine;dihydrochlorideIC5025700.0 [1]
1-[N'-[6-[[Amino-[[N'-[(2R)-2-ethylhexyl]carbamimidoyl]amino]methylidene]amino]hexyl]carbamimidoyl]-2-[(2R)-2-ethylhexyl]guanidineIC5021300.0 [1]
Items per page: 1 - 10 of 23
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References

This online tool may be cited as follows

MLA

"Quest Database™ Bcl-xL/BAK Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/bcl-xl-bak-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Bcl-xL/BAK Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/bcl-xl-bak-inhibitors-ic50-ki.
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