ATP-binding cassette sub-family G member 2 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Tert-butyl 3-[(2S,5S,8S)-14-methoxy-2-(2-methylpropyl)-4,7-dioxo-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraen-5-yl]propanoate	IC50	227.0 [1]
	Fumitremorgin C	IC50	731.0 [1]
	Fumitremorgin C	Ki	1300.0 [1]
	Tariquidar	IC50	850.0 [1]
	N-[2-[[4-[2-(3,4-Dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]phenyl]quinoline-3-carboxamide	IC50	721.0 [1]
	Elacridar	IC50	250.0 [1]
	Imatinib	IC50	500.0 [1], 900.0 [2], 3380.0 [3], 4070.0 [4], 4897.79 [5]
	4-Methoxy-N-[2-[2-(4-methoxyphenyl)tetrazol-5-yl]phenyl]benzamide	IC50	199.0 [1], 300.0 [2], 492.0 [3], 505.0 [4], 746.0 [5]
	Gefitinib	IC50	400.0 [1], 1100.0 [2], 1260.0 [3], 3190.0 [4]
	Novobiocin	IC50	25000.0 [1], 66069.34 [2], 85100.0 [3], 104000.0 [4]
	Retusin	IC50	390.0 [1], 540.0 [2], 570.0 [3], 900.0 [4]
	N,2-Diphenylquinazolin-4-amine	IC50	882.0 [1], 2570.0 [2]
	N-[2-[2-(3-Methoxyphenyl)tetrazol-5-yl]phenyl]-4-nitrobenzamide	IC50	78.9 [1], 307.0 [2], 387.0 [3], 585.0 [4]
	N-[2-[2-(4-Methoxyphenyl)tetrazol-5-yl]phenyl]-4-nitrobenzamide	IC50	118.0 [1], 378.0 [2], 535.0 [3], 587.0 [4]
	2-(3,4-Dimethoxyphenyl)-N-(4-nitrophenyl)quinazolin-4-amine	IC50	43.65 [1], 300.0 [2], 320.0 [3], 2960.0 [4]
	2-(3,4-Dimethoxyphenyl)-N-(3-nitrophenyl)quinazolin-4-amine	IC50	76.0 [1], 81.28 [2], 92.0 [3], 19400.0 [4]
	2-[(4-Nitrobenzoyl)amino]-N-(4-propylphenyl)benzamide	IC50	594.0 [1], 783.0 [2], 833.0 [3], 940.0 [4]
	Ayanin	IC50	460.0 [1], 680.0 [2], 5700.0 [3]
	(E)-1,3-Bis(3,4-dimethoxyphenyl)prop-2-en-1-one	IC50	3280.0 [1], 3800.0 [2], 5120.0 [3]
	N-[2-[[4-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]phenyl]-3,4-dimethoxybenzamide	IC50	860.0 [1], 930.0 [2], 2089.3 [3]
	2-Amino-N-(4-(2-(3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)benzamide	IC50	17800.0 [1], 20900.0 [2], 74131.02 [3]
	N-(4-(2-(3,4-Dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-2-nitrobenzamide	IC50	45700.0 [1], 51300.0 [2], 79432.82 [3]
	N-(4-(2-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-2-nitrobenzamide	IC50	40000.0 [1], 77600.0 [2], 109647.82 [3]
	2-Amino-N-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)benzamide	IC50	20700.0 [1], 32400.0 [2], 85113.8 [3]
	4-Amino-N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]benzamide	IC50	98200.0 [1], 219000.0 [2], 263026.8 [3]
	N-(4-(2-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-4-nitrobenzamide	IC50	4380.0 [1], 6920.0 [2], 7585.78 [3]
	N-[2-(2-Phenyltetrazol-5-yl)phenyl]benzamide	IC50	64.0 [1], 66.9 [2]
	N-[2-(3,4-Dimethoxyphenyl)ethyl]-4-oxo-5-phenylmethoxychromene-2-carboxamide	IC50	170.0 [1], 1800.0 [2]
	3-[[2-(3,4-Dimethoxyphenyl)quinazolin-4-yl]amino]benzonitrile	IC50	136.0 [1], 190.0 [2], 300.0 [3]
	4-Azido-N-[2-[2-(3-methoxyphenyl)tetrazol-5-yl]phenyl]benzamide	IC50	1267.0 [1], 1501.0 [2], 1615.0 [3]
	N-[2-[2-(3-Methoxyphenyl)tetrazol-5-yl]phenyl]-2-nitrobenzamide	IC50	1100.0 [1], 1320.0 [2], 1880.0 [3]
	1-[2-[2-(4-Methoxyphenyl)tetrazol-5-yl]phenyl]-3-(4-nitrophenyl)urea	IC50	331.0 [1], 541.0 [2], 718.0 [3]
	2-[(4-Nitrophenyl)carbamoylamino]-N-[4-(trifluoromethyl)phenyl]benzamide	IC50	452.0 [1], 605.0 [2], 711.0 [3]
	1-[2-[2-(3-Methoxyphenyl)tetrazol-5-yl]phenyl]-3-(2-nitrophenyl)urea	IC50	882.0 [1], 978.0 [2], 1172.0 [3]
	4-Isothiocyanato-N-[2-[2-(3-methoxyphenyl)tetrazol-5-yl]phenyl]benzamide	IC50	952.0 [1], 1050.0 [2], 1221.0 [3]
	4-[(2-Bromoacetyl)amino]-N-[2-[2-(3-methoxyphenyl)tetrazol-5-yl]phenyl]benzamide	IC50	283.0 [1], 446.0 [2], 605.0 [3]
	2-[(4-Methoxybenzoyl)amino]-N-(4-propylphenyl)benzamide	IC50	1656.0 [1], 2012.0 [2], 2526.0 [3]
	1-[2-[2-(3-Methoxyphenyl)tetrazol-5-yl]phenyl]-3-(4-nitrophenyl)urea	IC50	403.0 [1], 544.0 [2], 832.0 [3]
	2-[(2-Nitrophenyl)carbamoylamino]-N-(4-propylphenyl)benzamide	IC50	1120.0 [1], 2563.0 [2], 3662.0 [3]
	1-(4-Aminophenyl)-3-[2-[2-(3-methoxyphenyl)tetrazol-5-yl]phenyl]urea	IC50	379.0 [1], 571.0 [2], 838.0 [3]
	1-(4-Methoxyphenyl)-3-[2-[2-(4-methoxyphenyl)tetrazol-5-yl]phenyl]urea	IC50	355.0 [1], 382.0 [2], 442.0 [3]
	2-[(4-Nitrophenyl)carbamoylamino]-N-(4-propylphenyl)benzamide	IC50	325.0 [1], 482.0 [2], 622.0 [3]
	4-Acetamido-N-[2-[2-(3-methoxyphenyl)tetrazol-5-yl]phenyl]benzamide	IC50	1202.0 [1], 1325.0 [2], 1363.0 [3]
	1-(4-Isothiocyanatophenyl)-3-[2-[2-(3-methoxyphenyl)tetrazol-5-yl]phenyl]urea	IC50	550.0 [1], 667.0 [2], 1515.0 [3]
	2-[(3-Nitrobenzoyl)amino]-N-(4-propylphenyl)benzamide	IC50	512.0 [1], 727.0 [2], 785.0 [3]
	2-[(2-Nitrobenzoyl)amino]-N-(3-propylphenyl)benzamide	IC50	1713.0 [1], 2151.0 [2], 2814.0 [3]
	4-Amino-N-[2-[2-(3-methoxyphenyl)tetrazol-5-yl]phenyl]benzamide	IC50	299.0 [1], 491.0 [2], 549.0 [3]
	2-Bromo-N-[4-[[2-[2-(3-methoxyphenyl)tetrazol-5-yl]phenyl]carbamoylamino]phenyl]acetamide	IC50	472.0 [1], 583.0 [2], 798.0 [3]
	2-[(4-Methoxyphenyl)carbamoylamino]-N-(4-propylphenyl)benzamide	IC50	985.0 [1], 2173.0 [2], 3371.0 [3]
	2-[(3-Nitrophenyl)carbamoylamino]-N-(4-propylphenyl)benzamide	IC50	348.0 [1], 501.0 [2], 651.0 [3]
	N-[2-[2-(3-Methoxyphenyl)tetrazol-5-yl]phenyl]-4-propylbenzamide	IC50	131.0 [1], 207.0 [2], 354.0 [3]
	N-[2-[2-(3-Methoxyphenyl)tetrazol-5-yl]phenyl]-3-nitrobenzamide	IC50	866.0 [1], 1390.0 [2], 1801.0 [3]
	1-(4-Azidophenyl)-3-[2-[2-(3-methoxyphenyl)tetrazol-5-yl]phenyl]urea	IC50	685.0 [1], 691.0 [2], 913.0 [3]
	N-[4-[[2-[2-(3-Methoxyphenyl)tetrazol-5-yl]phenyl]carbamoylamino]phenyl]acetamide	IC50	325.0 [1], 454.0 [2], 627.0 [3]
	1-[2-[2-(3-Methoxyphenyl)tetrazol-5-yl]phenyl]-3-(3-nitrophenyl)urea	IC50	750.0 [1], 807.0 [2], 967.0 [3]
	2-[(4-Bromophenyl)carbamoylamino]-N-(4-propylphenyl)benzamide	IC50	952.0 [1], 2121.0 [2], 2655.0 [3]
	Cyclosporin A	IC50	63095.73 [1]
	Cyclosporin A	Ki	500.0 [1]
	Verapamil	IC50	50000.0 [1], 524807.46 [2]
	Quercetin	IC50	6900.0 [1], 7600.0 [2]
	Reserpine	IC50	12600.0 [1], 26302.68 [2]
	Estrone	IC50	3000.0 [1], 10000.0 [2]
	Genistein	IC50	6900.0 [1], 8800.0 [2]
	Diethylstilbestrol	IC50	500.0 [1]
	Apigenin	IC50	3100.0 [1], 5900.0 [2]
	Kaempferol	IC50	4700.0 [1], 6200.0 [2]
	beta-Naphthoflavone	IC50	6050.0 [1], 8320.0 [2]
	Flavone	IC50	17000.0 [1], 26000.0 [2]
	Morin	IC50	21000.0 [1], 49000.0 [2]
	Chrysin	IC50	1500.0 [1], 2600.0 [2]
	alpha-Naphthoflavone	IC50	1310.0 [1], 1400.0 [2]
	Dolutegravir	IC50	30000.0 [1], 67000.0 [2]
	Nobiletin	IC50	4400.0 [1], 4900.0 [2]
	N-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-amine	IC50	1730.0 [1], 2320.0 [2]
	Tangeretin	IC50	17000.0 [1], 19000.0 [2]
	5,7-Dimethoxyflavone	IC50	9200.0 [1], 11000.0 [2]
	Sinensetin	IC50	8300.0 [1], 9000.0 [2]
	(S)-2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4-benzopyrone	IC50	8900.0 [1], 31000.0 [2]
	3,3',4',5,6,7,8-Heptamethoxyflavone	IC50	1400.0 [1], 1600.0 [2]
	Diethylstilbestrol dipropionate	IC50	3000.0 [1]
	2'-Hydroxy-4,4',6'-trimethoxychalcone	IC50	3000.0 [1], 5830.0 [2]
	6-Methoxyflavone	IC50	3400.0 [1], 10000.0 [2]
	Quercetin pentamethyl ether	IC50	822.0 [1], 1880.0 [2]
	3-Methoxyflavone	IC50	1210.0 [1], 1280.0 [2]
	Megalip	IC50	1910.0 [1], 2340.0 [2]
	Penduletin	IC50	1200.0 [1], 2000.0 [2]
	6-Methoxyflavanone	IC50	19000.0 [1], 46000.0 [2]
	1-(2-Hydroxy-4-methoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one	IC50	2200.0 [1], 4200.0 [2]
	2',4'-Dihydroxy-4-methoxychalcone	IC50	12050.0 [1], 33320.0 [2]
	2'-Hydroxy-4'-Methoxychalcone	IC50	30950.0 [1], 31020.0 [2]
	5,7-Dimethoxyflavanone	IC50	17000.0 [1], 32000.0 [2]
	3-(3,4-Dimethoxyphenyl)-1-(2-hydroxy-4-methoxyphenyl)prop-2-en-1-one	IC50	1060.0 [1], 2170.0 [2]
	3',4'-Dimethoxy-alpha-naphthoflavone	IC50	1130.0 [1], 1230.0 [2]
	2',4'-Dihydroxy-4-chlorochalcone	IC50	6070.0 [1], 6370.0 [2]
	(E)-3-(4-Chlorophenyl)-1-(2-hydroxy-4-methoxyphenyl)prop-2-en-1-one	IC50	10720.0 [1], 13510.0 [2]
	N-[3-(Trifluoromethyl)phenyl]-4-quinazolinamine	IC50	940.0 [1], 1550.0 [2]
	N-(3-Bromophenyl)quinazolin-4-amine	IC50	1080.0 [1], 1480.0 [2]
	2-(3,4-Dimethoxyphenyl)-3-hydroxy-7-methoxy-4H-chromen-4-one	IC50	1010.0 [1], 1770.0 [2]
	6,7-Dimethoxy-N-(3-(trifluoromethyl)phenyl)quinazolin-4-amine	IC50	1980.0 [1], 2400.0 [2]
	2-Chloro-4',6'-dimethoxy-2'-hydroxychalcone	IC50	2820.0 [1], 5270.0 [2]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ ATP-binding cassette sub-family G member 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/atp-binding-cassette-sub-family-g-member-2-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 21). Quest Database™ ATP-binding cassette sub-family G member 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/atp-binding-cassette-sub-family-g-member-2-inhibitors-ic50-ki.
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