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Arginase-2, mitochondrial Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
(2S)-2-Amino-6-boronohexanoic acidIC502150.0 [1]
(2S)-2-Amino-6-boronohexanoic acidKi8.5 [1]
2-Amino-6-borono-2-(2-pyrrolidin-1-ylethyl)hexanoic acidIC50620.0 [1]
2-Amino-6-boronohexanoic acidIC501920.0 [1]
2-Amino-6-borono-2-methylhexanoic acidIC505070.0 [1]
Nor-NOHAKi51.0 [1]
Arginase inhibitor 1IC50509.0 [1]
2-[4-(Diaminomethylideneamino)phenyl]-2-fluoroacetic acidKi322000.0 [1]
2-Acetyloxy-2-[4-(diaminomethylideneamino)phenyl]acetic acidKi437000.0 [1]
2-Amino-6-borono-2-(hydroxymethyl)hexanoic acidIC504280.0 [1]
2-Amino-6-borono-2-(3-hydroxypropyl)hexanoic acidIC504500.0 [1]
2-Amino-2-benzyl-6-boronohexanoic acidIC5017000.0 [1]
2-Amino-2-[(benzylamino)methyl]-6-boronohexanoic acidIC505980.0 [1]
2-Amino-6-borono-2-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]hexanoic acidIC50240.0 [1]
(2R)-2-Amino-6-borono-2-[2-[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]ethyl]hexanoic acidIC501710.0 [1]
(2R)-2-Amino-6-borono-2-[2-(4-hydroxypiperidin-1-yl)ethyl]hexanoic acidIC50420.0 [1]
(2R)-2-Amino-6-borono-2-[2-[(3R)-3-(hydroxymethyl)pyrrolidin-1-yl]ethyl]hexanoic acidIC50600.0 [1]
(2R)-2-Amino-6-borono-2-(2-thiomorpholin-4-ylethyl)hexanoic acidIC502560.0 [1]
(2R)-2-Amino-6-borono-2-[2-(diethylamino)ethyl]hexanoic acidIC50270.0 [1]
2-Amino-6-borono-2-[1-[(3,4-dichlorophenyl)methyl]piperidin-4-yl]hexanoic acidIC50290.0 [1]
2-Amino-6-borono-2-[1-[(4-chlorophenyl)carbamoyl]piperidin-4-yl]hexanoic acidIC501100.0 [1]
2-Amino-6-borono-2-(1H-imidazol-5-ylmethyl)hexanoic acidIC503720.0 [1]
(2R)-2-Amino-6-borono-2-[2-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]ethyl]hexanoic acidIC50340.0 [1]
2-Amino-6-borono-2-[1-[3-[4-(trifluoromethyl)phenyl]propyl]piperidin-4-yl]hexanoic acidIC5070.0 [1]
2-Amino-6-borono-2-[1-[3-(2,4-dichlorophenyl)propyl]piperidin-4-yl]hexanoic acidIC5050.0 [1]
2-Amino-6-borono-2-[2-(4-hydroxypiperidin-1-yl)ethyl]hexanoic acidIC50980.0 [1]
2-Amino-6-borono-2-piperidin-4-ylhexanoic acidIC50640.0 [1]
2-Amino-2-(1-benzylpiperidin-4-yl)-6-boronohexanoic acidIC50230.0 [1]
2-Amino-6-borono-2-[1-(3-methylbutyl)piperidin-4-yl]hexanoic acidIC50230.0 [1]
2-Amino-6-borono-2-(2-morpholin-4-ylethyl)hexanoic acidIC504020.0 [1]
2-Amino-6-borono-2-[1-[2-(2,4-dichlorophenyl)ethyl]piperidin-4-yl]hexanoic acidIC50330.0 [1]
(2S)-2-Amino-6-borono-2-(2-piperidin-1-ylethyl)hexanoic acidIC50300000.0 [1]
2-Amino-6-borono-2-[8-[(4-chlorophenyl)methyl]-8-azabicyclo[3.2.1]octan-3-yl]hexanoic acidIC5030.0 [1]
2-Amino-6-borono-2-[8-[(3,4-dichlorophenyl)methyl]-8-azabicyclo[3.2.1]octan-3-yl]hexanoic acidIC5023.0 [1]
2-Amino-2-(8-azabicyclo[3.2.1]octan-3-yl)-6-boronohexanoic acidIC5085.0 [1]
2-Amino-2-(8-benzyl-8-azabicyclo[3.2.1]octan-3-yl)-6-boronohexanoic acidIC5047.0 [1]
2-Amino-6-borono-2-[8-[(3,4-difluorophenyl)methyl]-8-azabicyclo[3.2.1]octan-3-yl]hexanoic acidIC5033.0 [1]
(2R)-2-Amino-6-borono-2-[2-[ethyl(2-hydroxyethyl)amino]ethyl]hexanoic acidIC50390.0 [1]
(2R)-2-Amino-6-borono-2-[2-[methyl(propyl)amino]ethyl]hexanoic acidIC50320.0 [1]
(2R)-2-Amino-6-borono-2-[2-(propan-2-ylamino)ethyl]hexanoic acidIC50190.0 [1]
2-Amino-6-borono-2-ethylhexanoic acidIC504600.0 [1]
2-Amino-6-borono-2-(2-hydroxyethyl)hexanoic acidIC5057000.0 [1]
2-Amino-6-borono-2-(3-methoxypropyl)hexanoic acidIC506440.0 [1]
(R)-2-(Methylamino)-6-(dihydroxyboryl)-2-(2-piperidinoethyl)hexanoic acidIC5067.0 [1]
(2R)-2-Amino-6-borono-2-[2-(3,4-dihydro-1H-isoquinolin-2-yl)ethyl]hexanoic acidIC501090.0 [1]
(2R)-2-Amino-6-borono-2-(2-pyrrolidin-1-ylethyl)hexanoic acidIC50310.0 [1]
(2R)-2-Amino-6-borono-2-[2-(1,3-dihydroisoindol-2-yl)ethyl]hexanoic acidIC50550.0 [1]
2-Amino-6-borono-2-[2-(diethylamino)ethyl]hexanoic acidIC50934.0 [1]
2-Amino-2-(aminomethyl)-6-boronohexanoic acidIC501350.0 [1]
(2R)-2-Amino-6-boronohexanoic acidIC501920.0 [1]
2-Amino-6-borono-2-propan-2-ylhexanoic acidIC5015500.0 [1]
2-Amino-6-borono-2-[1-(4-methylphenyl)sulfonylpiperidin-4-yl]hexanoic acidIC504650.0 [1]
2-Amino-6-borono-2-[1-[(4-chlorophenyl)methylcarbamothioyl]piperidin-4-yl]hexanoic acidIC501120.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Arginase-2, mitochondrial Inhibitors (IC50, Ki)." AAT Bioquest, Inc.20 Nov2024https://www.aatbio.com/data-sets/arginase-2-mitochondrial-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024November 20). Quest Database™ Arginase-2, mitochondrial Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/arginase-2-mitochondrial-inhibitors-ic50-ki.
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