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Arginase-1 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
2-Amino-6-boronohexanoic acidIC50800.0 [1], 1450.0 [2]
Arginase inhibitor 1IC50223.0 [1], 3000.0 [2]
2-Amino-6-borono-2-(2-pyrrolidin-1-ylethyl)hexanoic acidIC50320.0 [1]
(2S)-2-Amino-6-borono-2-(2-piperidin-1-ylethyl)hexanoic acidIC5019000.0 [1], 300000.0 [2]
(2R)-2-Amino-6-boronohexanoic acidIC501450.0 [1], 8000.0 [2]
1H-Imidazol-2-amineKi3600000.0 [1]
(2S)-2-Amino-6-boronohexanoic acidIC501470.0 [1]
2-Amino-6-borono-2-methylhexanoic acidIC503430.0 [1]
(2S)-2-Amino-5-(2-aminoimidazol-1-yl)pentanoic AcidKi4000.0 [1]
2-Amino-L-histidineKi300000.0 [1]
2-[4-(Diaminomethylideneamino)phenyl]-2-fluoroacetic acidKi275000.0 [1]
2-Acetyloxy-2-[4-(diaminomethylideneamino)phenyl]acetic acidKi382000.0 [1]
(2s)-2-Amino-4-(2-Amino-1h-Imidazol-5-Yl)butanoic AcidKi3000000.0 [1]
(2S)-2-Amino-5-(1H-imidazol-2-ylamino)pentanoic acidKi500000.0 [1]
2-Amino-5-(2-amino-1H-imidazol-5-yl)pentanoic acidKi80000000.0 [1]
2-Amino-6-borono-2-(hydroxymethyl)hexanoic acidIC502250.0 [1]
2-Amino-2-benzyl-6-boronohexanoic acidIC5010500.0 [1]
2-Amino-2-[(benzylamino)methyl]-6-boronohexanoic acidIC503260.0 [1]
2-Amino-6-borono-2-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]hexanoic acidIC50190.0 [1]
(2R)-2-Amino-6-borono-2-[2-[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]ethyl]hexanoic acidIC501750.0 [1]
(2R)-2-Amino-6-borono-2-[2-(4-hydroxypiperidin-1-yl)ethyl]hexanoic acidIC50230.0 [1]
(2R)-2-Amino-6-borono-2-[2-[(3R)-3-(hydroxymethyl)pyrrolidin-1-yl]ethyl]hexanoic acidIC50260.0 [1]
(2R)-2-Amino-6-borono-2-(2-thiomorpholin-4-ylethyl)hexanoic acidIC501240.0 [1]
(2R)-2-Amino-6-borono-2-[2-(diethylamino)ethyl]hexanoic acidIC50270.0 [1]
2-Amino-6-borono-2-[1-[(3,4-dichlorophenyl)methyl]piperidin-4-yl]hexanoic acidIC50200.0 [1]
2-Amino-6-borono-2-[1-[(4-chlorophenyl)carbamoyl]piperidin-4-yl]hexanoic acidIC50720.0 [1]
2-Amino-6-borono-2-(1H-imidazol-5-ylmethyl)hexanoic acidIC502280.0 [1]
(2R)-2-Amino-6-borono-2-[2-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]ethyl]hexanoic acidIC50210.0 [1]
2-Amino-6-borono-2-[1-[3-[4-(trifluoromethyl)phenyl]propyl]piperidin-4-yl]hexanoic acidIC50120.0 [1]
2-Amino-6-borono-2-[1-[3-(2,4-dichlorophenyl)propyl]piperidin-4-yl]hexanoic acidIC50100.0 [1]
2-Amino-6-borono-2-[2-(4-hydroxypiperidin-1-yl)ethyl]hexanoic acidIC50370.0 [1]
2-Amino-6-borono-2-piperidin-4-ylhexanoic acidIC50380.0 [1]
2-Amino-2-(1-benzylpiperidin-4-yl)-6-boronohexanoic acidIC50200.0 [1]
2-Amino-6-borono-2-[1-(3-methylbutyl)piperidin-4-yl]hexanoic acidIC50180.0 [1]
2-Amino-6-borono-2-(2-morpholin-4-ylethyl)hexanoic acidIC505380.0 [1]
2-Amino-6-borono-2-[1-[2-(2,4-dichlorophenyl)ethyl]piperidin-4-yl]hexanoic acidIC50210.0 [1]
2-Amino-6-borono-2-[8-[(4-chlorophenyl)methyl]-8-azabicyclo[3.2.1]octan-3-yl]hexanoic acidIC5017.0 [1]
2-Amino-6-borono-2-[8-[(3,4-dichlorophenyl)methyl]-8-azabicyclo[3.2.1]octan-3-yl]hexanoic acidIC5021.0 [1]
2-Amino-2-(8-azabicyclo[3.2.1]octan-3-yl)-6-boronohexanoic acidIC5080.0 [1]
2-Amino-2-(8-benzyl-8-azabicyclo[3.2.1]octan-3-yl)-6-boronohexanoic acidIC5024.0 [1]
2-Amino-6-borono-2-[8-[(3,4-difluorophenyl)methyl]-8-azabicyclo[3.2.1]octan-3-yl]hexanoic acidIC5022.0 [1]
(2R)-2-Amino-6-borono-2-[2-[ethyl(2-hydroxyethyl)amino]ethyl]hexanoic acidIC50550.0 [1]
(2R)-2-Amino-6-borono-2-[2-[methyl(propyl)amino]ethyl]hexanoic acidIC50140.0 [1]
(2R)-2-Amino-6-borono-2-[2-(propan-2-ylamino)ethyl]hexanoic acidIC50100.0 [1]
2-Amino-6-borono-2-ethylhexanoic acidIC504100.0 [1]
2-Amino-6-borono-2-(2-hydroxyethyl)hexanoic acidIC5019000.0 [1]
2-Amino-6-borono-2-(3-methoxypropyl)hexanoic acidIC505120.0 [1]
(R)-2-(Methylamino)-6-(dihydroxyboryl)-2-(2-piperidinoethyl)hexanoic acidIC5059.7 [1]
(2R)-2-Amino-6-borono-2-[2-(3,4-dihydro-1H-isoquinolin-2-yl)ethyl]hexanoic acidIC50510.0 [1]
(2R)-2-Amino-6-borono-2-(2-pyrrolidin-1-ylethyl)hexanoic acidIC50160.0 [1]
(2R)-2-Amino-6-borono-2-[2-(1,3-dihydroisoindol-2-yl)ethyl]hexanoic acidIC50270.0 [1]
2-Amino-6-borono-2-[2-(diethylamino)ethyl]hexanoic acidIC50520.0 [1]
2-Amino-2-(aminomethyl)-6-boronohexanoic acidIC502070.0 [1]
2-Amino-6-borono-2-propan-2-ylhexanoic acidIC5011240.0 [1]
2-Amino-6-borono-2-[1-(4-methylphenyl)sulfonylpiperidin-4-yl]hexanoic acidIC506650.0 [1]
2-Amino-6-borono-2-[1-[(4-chlorophenyl)methylcarbamothioyl]piperidin-4-yl]hexanoic acidIC50330.0 [1]
Items per page: 1 - 10 of 56
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References

This online tool may be cited as follows

MLA

"Quest Database™ Arginase-1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Nov. 2024, https://www.aatbio.com/data-sets/arginase-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, November 21). Quest Database™ Arginase-1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/arginase-1-inhibitors-ic50-ki.
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