Arachidonate 15-lipoxygenase, type II Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Quercetin	IC50	100000.0 [1]
	Baicalein	IC50	100000.0 [1]
	Nordihydroguaiaretic acid	IC50	11000.0 [1]
	3-Hydroxyflavone	IC50	100000.0 [1]
	Fisetin	IC50	100000.0 [1]
	7-Hydroxyflavone	IC50	100000.0 [1]
	6-Hydroxyflavone	IC50	100000.0 [1]
	Chloroxine	IC50	28000.0 [1]
	6,7,4'-Trihydroxyisoflavone	IC50	100000.0 [1]
	3,7-Dihydroxyflavone	IC50	100000.0 [1]
	3,6-Dihydroxyflavone	IC50	100000.0 [1]
	13-Keto-9Z,11E-octadecadienoic acid	IC50	100000.0 [1]
	5-Oxo-ETE	IC50	100000.0 [1]
	N-[(5-Chloro-8-hydroxyquinolin-7-yl)-(furan-2-yl)methyl]propanamide	IC50	100000.0 [1]
	15-Oxo-ETE	IC50	100000.0 [1]
	3,5-Dihydroxyflavone	IC50	100000.0 [1]
	12-Oxo-ETE	IC50	100000.0 [1]
	4-{[5-(1-Naphthyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-2-butynyl 2-thiophenecarboxylate	IC50	100000.0 [1]
	5-(Methylamino)-2-naphthalen-1-yl-1,3-oxazole-4-carbonitrile	IC50	50000.0 [1]
	CID 70701426	IC50	100000.0 [1]
	Texasin	IC50	100000.0 [1]
	4-[(2-Hydroxy-3-methoxybenzyl)amino]-N-1,3-thiazol-2-ylbenzenesulfonamide	IC50	40000.0 [1]
	N-[(8-Hydroxyquinolin-7-yl)-thiophen-2-ylmethyl]propanamide	IC50	100000.0 [1]
	4-(5-(Naphthalen-1-yl)-1,3,4-oxadiazol-2-ylthio)but-2-ynyl benzo[b]thiophene-2-carboxylate	IC50	100000.0 [1]
	N-[(5-Bromo-8-hydroxy-7-quinolinyl)-thiophen-2-ylmethyl]acetamide	IC50	100000.0 [1]
	4-Methyl-2-[5-(2-methylphenyl)-1H-pyrazol-3-yl]phenol	IC50	50000.0 [1]
	CID 24825377	IC50	51.0 [1]
	6,7,4'-Trihydroxyisoflavanone	IC50	100000.0 [1]
	6,7,4'-Trihydroxyisoflavan	IC50	71000.0 [1]
	6-Phenyl-[1,3]dioxolo[4,5-g]chromen-8-one	IC50	100000.0 [1]
	4H-1-Benzopyran-4-one, 2-(1,1-dimethylethyl)-6-hydroxy-	IC50	100000.0 [1]
	2,3-Dihydro-6,7-dihydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one	IC50	100000.0 [1]
	7,8-Dihydroxy-3-(3-chlorophenyl)-4H-1-benzopyran-4-one	IC50	100000.0 [1]
	3-(4-Chlorophenyl)-7,8-dihydroxy-4H-chromen-4-one	IC50	100000.0 [1]
	3-(3,4-Dimethoxyphenyl)-3,4-dihydro-2H-1-benzopyran-7,8-diol	IC50	100000.0 [1]
	3-(4-Methoxyphenyl)-7,8-dihydroxychroman	IC50	100000.0 [1]
	7,8-Dihydroxyisoflavone	IC50	100000.0 [1]
	3-[3-(Trifluoromethyl)phenyl]-7,8-dihydroxy-4H-1-benzopyran-4-one	IC50	100000.0 [1]
	4H-1-Benzopyran-4-one, 6-hydroxy-2-propyl-	IC50	100000.0 [1]
	N-[2-[4-(4-Methoxyphenyl)-2-thiophen-2-yl-1H-imidazol-5-yl]ethyl]-4-pentylbenzenesulfonamide	IC50	147.0 [1]
	6-Hydroxy-2-isobutyl-4H-benzopyran-4-one	IC50	100000.0 [1]
	3-(3-Methylphenyl)-6-hydroxy-7-hydroxychroman	IC50	8300.0 [1]
	3,4-Dihydro-3-(4-methoxyphenyl)-2H-1-benzopyran-6,7-diol	IC50	100000.0 [1]
	Benzoic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester	IC50	100000.0 [1]
	7,8-Dihydroxy-3-(3-methylphenyl)-4H-1-benzopyran-4-one	IC50	100000.0 [1]
	3-(1,3-Benzodioxol-5-yl)-3,4-dihydro-2H-1-benzopyran-6,7-diol	IC50	16000.0 [1]
	7-Hydroxy-2-t-butyl-4H-benzopyran-4-one	IC50	100000.0 [1]
	7-Hydroxy-2-pentyl-4H-benzopyran-4-one	IC50	100000.0 [1]
	6,7-Dihydroxy-3-(1,3-benzodioxol-5-yl)-4H-1-benzopyran-4-one	IC50	100000.0 [1]
	N-[2-[4-(4-Methoxyphenyl)-2-phenyl-1H-imidazol-5-yl]ethyl]-4-pentylbenzenesulfonamide	IC50	402.0 [1]
	4-(3,4-Dichlorophenyl)-N-[2-[4-(4-methoxyphenyl)-2-thiophen-2-yl-1H-imidazol-5-yl]ethyl]piperazine-1-sulfonamide	IC50	433.0 [1]
	5-[2-[[[(3R)-1-Benzylpyrrolidin-3-yl]-methylsulfamoyl]amino]ethyl]-4-(4-methoxyphenyl)-2-phenyl-1H-imidazole	IC50	3130.0 [1]
	3-(4-Methylphenyl)-3,4-dihydro-2H-1-benzopyran-7,8-diol	IC50	100000.0 [1]
	2-Ethyl-6-hydroxy-4H-benzopyran-4-one	IC50	100000.0 [1]
	6-Hydroxy-2-isopropyl-4H-benzopyran-4-one	IC50	100000.0 [1]
	6-Hydroxy-2-pentyl-4H-benzopyran-4-one	IC50	100000.0 [1]
	7-Hydroxy-2-isopropyl-4H-benzopyran-4-one	IC50	100000.0 [1]
	7-Hydroxy-2-isobutyl-4H-benzopyran-4-one	IC50	100000.0 [1]
	6-Tert-butyl-[1,3]dioxolo[4,5-g]chromen-8-one	IC50	100000.0 [1]
	6-(2-Methylpropyl)-[1,3]dioxolo[4,5-g]chromen-8-one	IC50	100000.0 [1]
	6,7-Dihydroxy-2-t-butylbenzopyran-4-one	IC50	100000.0 [1]
	2-Ethyl-3-hydroxy-4H-benzopyran-4-one	IC50	100000.0 [1]
	2-Isopropyl-3-hydroxy-4H-benzopyran-4-one	IC50	100000.0 [1]
	3-Hydroxy-2-propyl-4H-benzopyran-4-one	IC50	100000.0 [1]
	2-Isobutyl-3-hydroxy-4H-benzopyran-4-one	IC50	100000.0 [1]
	3-Hydroxy-2-t-butyl-4H-benzopyran-4-one	IC50	100000.0 [1]
	3-Hydroxy-2-pentyl-4H-benzopyran-4-one	IC50	100000.0 [1]
	6,7-Dihydroxy-3-(3-hydroxy-4-nitrophenyl)chromen-4-one	IC50	100000.0 [1]
	6,7-Dihydroxy-3-m-tolyl-2,3-dihydrochromen-4-one	IC50	100000.0 [1]
	3-Thiophenecarboxylic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester	IC50	100000.0 [1]
	3,4-Difluorobenzoic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester	IC50	100000.0 [1]
	4-(Trifluoromethoxy)benzoic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester	IC50	100000.0 [1]
	4-(Trifluoromethyl)benzoic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester	IC50	100000.0 [1]
	3-Fluorobenzoic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester	IC50	100000.0 [1]
	4-{[5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}but-2-yn-1-yl 4-fluorobenzoate	IC50	100000.0 [1]
	4-(5-(Naphthalen-2-yl)-1,3,4-oxadiazol-2-ylthio)but-2-ynyl-4-fluorobenzoate	IC50	100000.0 [1]
	7,8-Dihydroxy-3-(4-methylphenyl)-4H-1-benzopyran-4-one	IC50	100000.0 [1]
	4H-1-Benzopyran-4-one, 7-hydroxy-2-propyl-	IC50	100000.0 [1]
	N-(1H-Benzimidazol-2-yl)-4-[(2-hydroxy-3-methoxyphenyl)methylamino]benzenesulfonamide	IC50	100000.0 [1]
	N-(1,3-Benzoxazol-2-yl)-4-[(2-hydroxy-3-methoxyphenyl)methylamino]benzenesulfonamide	IC50	100000.0 [1]
	2-(2,3-Dichlorophenyl)-5-(methylamino)-1,3-oxazole-4-carbonitrile	IC50	50000.0 [1]
	2-(3,4-Dichlorophenyl)-5-(methylamino)-1,3-oxazole-4-carbonitrile	IC50	50000.0 [1]
	5-(Methylamino)-2-naphthalen-1-yl-1,3-thiazole-4-carbonitrile	IC50	50000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 83 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Arachidonate 15-lipoxygenase, type II Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/arachidonate-15-lipoxygenase-type-ii-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 20). Quest Database™ Arachidonate 15-lipoxygenase, type II Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/arachidonate-15-lipoxygenase-type-ii-inhibitors-ic50-ki.
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