 | Abt-737 | IC50 | 1.0 [1], 6.0 [2], 64.0 [3] |
| Abt-737 | Ki | 1.0 [1], 188.4 [2] |
 | N-[4-[[(2R)-4-(Dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonyl-4-(4,4-dimethylpiperidin-1-yl)benzamide | IC50 | 360.0 [1] |
 | Gossypol | IC50 | 480.0 [1], 500.0 [2], 2720.0 [3] |
| Gossypol | Ki | 620.0 [1] |
 | Navitoclax | IC50 | 3.3 [1], 8.2 [2], 60.0 [3] |
| Navitoclax | Ki | 0.06 [1], 1.0 [2] |
 | 4-(4-Fluorophenyl)-N-[3-nitro-4-(2-phenylsulfanylethylamino)phenyl]sulfonylbenzamide | IC50 | 122.0 [1], 1500.0 [2], 2200.0 [3], 10000.0 [4] |
| 4-(4-Fluorophenyl)-N-[3-nitro-4-(2-phenylsulfanylethylamino)phenyl]sulfonylbenzamide | Ki | 36.0 [1], 2500.0 [2] |
 | Venetoclax | IC50 | 52.7 [1] |
| Venetoclax | Ki | 48.0 [1] |
 | (2S)-N-(4-Methylphenyl)sulfonyl-2-[(5Z)-4-oxo-5-[(4-phenylphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-phenylpropanamide | Ki | 570.0 [1], 660.0 [2], 720.0 [3], 810.0 [4], 1200.0 [5] |
 | N-[4-[[(2R)-4-(Dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonyl-4-[4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]benzamide | IC50 | 85.0 [1] |
| N-[4-[[(2R)-4-(Dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonyl-4-[4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]benzamide | Ki | 0.5 [1], 3.5 [2], 11.0 [3], 200.0 [4] |
 | Apogossypol | IC50 | 1700.0 [1], 3690.0 [2], 3700.0 [3] |
| Apogossypol | Ki | 3690.0 [1] |
 | 5-(p-Bromobenzylidine)-alpha-isopropyl-4-oxo-2-thioxo-3-thiozolidineacetic Acid | Ki | 2400.0 [1], 8700.0 [2], 10000.0 [3] |
 | 2-[(4-Chlorophenyl)sulfanyl]-4-(4-cyclohexylphenyl)-4-oxobutanoic acid | IC50 | 18000.0 [1], 19000.0 [2] |
| 2-[(4-Chlorophenyl)sulfanyl]-4-(4-cyclohexylphenyl)-4-oxobutanoic acid | Ki | 4700.0 [1], 13000.0 [2] |
 | 2,3,5-Trihydroxy-7-methyl-N-(2-phenylpropyl)-6-[1,6,7-trihydroxy-3-methyl-5-(2-phenylpropylcarbamoyl)naphthalen-2-yl]naphthalene-1-carboxamide | IC50 | 110.0 [1], 390.0 [2], 760.0 [3] |
 | CID 59447577 | Ki | 0.01 [1], 0.1 [2] |
 | 4-(4-Chlorophenyl)-1-[(3S)-3,4-dihydroxybutyl]-N-[3-(4-methylpiperazin-1-yl)propyl]-3-phenylpyrrole-2-carboxamide | Ki | 138000.0 [1] |
 | 3-(5-((2-(Benzo[d]thiazol-2-yl)hydrazono)methyl)furan-2-yl)-2-methylbenzoic acid | IC50 | 6800.0 [1], 7700.0 [2], 20000.0 [3] |
 | 5-Benzyl-2-(5-benzyl-1,4,6,7-tetrahydroxy-3-methylnaphthalen-2-yl)-3-methylnaphthalene-1,4,6,7-tetrone | IC50 | 76.0 [1], 340.0 [2] |
| 5-Benzyl-2-(5-benzyl-1,4,6,7-tetrahydroxy-3-methylnaphthalen-2-yl)-3-methylnaphthalene-1,4,6,7-tetrone | Ki | 230.0 [1] |
 | 4-[2-Methoxy-4-(3-morpholin-4-ylpropyl)phenyl]-N-[3-nitro-4-(2-phenylsulfanylethylamino)phenyl]sulfonylbenzamide | Ki | 10.4 [1], 580.0 [2], 4300.0 [3] |
 | 4-[4-[3-(Dimethylamino)propyl]-2-methoxyphenyl]-N-[3-nitro-4-(2-phenylsulfanylethylamino)phenyl]sulfonylbenzamide | Ki | 106.0 [1], 730.0 [2], 5660.0 [3] |
 | N-[4-[[(2R)-4-(Dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonyl-4-[3,5-dimethyl-4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]benzamide | Ki | 68.0 [1], 96.0 [2], 140.0 [3] |
 | N-[4-[[(2R)-4-(Dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonyl-4-[(2S)-2-propan-2-yl-4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]benzamide | Ki | 3.3 [1], 63.0 [2], 83.0 [3] |
 | N-[4-[[(2R)-4-(Dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonyl-4-[(2R)-2-propan-2-yl-4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]benzamide | Ki | 2.6 [1], 42.0 [2], 280.0 [3] |
 | N-[4-[[(2R)-4-(Dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonyl-4-[(3S)-3-methyl-4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]benzamide | Ki | 1.0 [1], 99.0 [2] |
 | N-[4-[[(2R)-4-(Dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonyl-4-[(3R)-3-methyl-4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]benzamide | Ki | 1.0 [1], 3.7 [2], 81.0 [3] |
 | (2Z)-2-[(5Z)-5-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylidene]-4-methoxypyrrol-2-ylidene]indole | IC50 | 4690.0 [1] |
 | Apogossypolone | IC50 | 630.0 [1] |
 | N-[4-(2-Tert-Butylphenylsulfonyl)phenyl]-2,3,4-trihydroxy-5-(2-isopropylbenzyl)benzamide | Ki | 1110.0 [1] |
 | CID 71297207 | IC50 | 1.1 [1], 3.0 [2] |
 | 2-{4-[(4-Chlorophenyl)thio]-3-nitrobenzoyl}benzoic acid | IC50 | 500.0 [1] |
| 2-{4-[(4-Chlorophenyl)thio]-3-nitrobenzoyl}benzoic acid | Ki | 500.0 [1] |
 | 4-[8-Ethylsulfanyl-3-(4-hydroxyphenyl)-3-methyloctan-4-yl]phenol | Ki | 58900.0 [1], 659600.0 [2] |
 | 4-(1,3-Benzodioxol-5-yl)-6-(2-hydroxyphenyl)-2-oxo-1H-pyridine-3-carbonitrile | IC50 | 5100.0 [1] |
| 4-(1,3-Benzodioxol-5-yl)-6-(2-hydroxyphenyl)-2-oxo-1H-pyridine-3-carbonitrile | Ki | 5100.0 [1] |
 | 6-(8-(2-(Benzothiazol-2-yl)hydrazono)-5,6,7,8-tetrahydronaphthalen-2-yl)picolinic acid | IC50 | 20.0 [1], 21.0 [2] |
 | 5-(4-Chlorophenyl)-4-[3-[4-[4-[[4-[[(2R)-4-(dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonylamino]phenyl]piperazin-1-yl]phenyl]-1-ethyl-2-methylpyrrole-3-carboxylic acid | IC50 | 6.6 [1] |
 | 5-(4-Chlorophenyl)-4-[3-[4-[4-[[4-[[(2R)-4-(dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonylamino]phenyl]piperazin-1-yl]phenyl]-1,2-dimethylpyrrole-3-carboxylic acid | IC50 | 6.0 [1] |
 | N-[7-[4-[[2-(4-Chlorophenyl)phenyl]methyl]piperazin-1-yl]quinazolin-4-yl]-4-[[(2R)-4-(dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrobenzenesulfonamide | IC50 | 3.0 [1], 7.0 [2] |
 | 2-[8-(1,3-Benzothiazol-2-ylcarbamoyl)-3,4-dihydro-1H-isoquinolin-2-yl]-5-[3-(4-pyrazolo[3,4-d]pyrimidin-1-ylphenoxy)propyl]-1,3-thiazole-4-carboxylic acid | Ki | 0.04 [1], 0.38 [2] |
 | 4-Benzamido-N-[3-nitro-4-(2-phenylsulfanylethylamino)phenyl]sulfonylbenzamide | Ki | 630.0 [1], 2510.0 [2] |
 | 4-[5-Butyl-3-(hydroxymethyl)-1-phenylpyrazol-4-yl]-3-(3,4-dihydro-1H-isoquinoline-2-carbonyl)-N-(2-trimethylsilylethylsulfonyl)benzamide | IC50 | 13.0 [1] |
 | 4-(4-Chlorophenyl)-3-[3-[4-[4-[[4-[[(2R)-4-(dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonylamino]phenyl]piperazin-1-yl]phenyl]-5-ethyl-1-methylpyrrole-2-carboxylic acid | IC50 | 7.5 [1] |
| 4-(4-Chlorophenyl)-3-[3-[4-[4-[[4-[[(2R)-4-(dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonylamino]phenyl]piperazin-1-yl]phenyl]-5-ethyl-1-methylpyrrole-2-carboxylic acid | Ki | 1.0 [1] |
 | 5-(4-Chlorophenyl)-4-[3-[4-[4-[[4-[[(2R)-4-(dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonylamino]phenyl]piperazin-1-yl]phenyl]-N,1,2-trimethylpyrrole-3-carboxamide | IC50 | 6.0 [1] |
 | N-[4-[4-[3-[2-(4-Chlorophenyl)-1,5-dimethylpyrrol-3-yl]phenyl]piperazin-1-yl]phenyl]-4-[[(2R)-4-(dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrobenzenesulfonamide | IC50 | 11.0 [1] |
| N-[4-[4-[3-[2-(4-Chlorophenyl)-1,5-dimethylpyrrol-3-yl]phenyl]piperazin-1-yl]phenyl]-4-[[(2R)-4-(dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrobenzenesulfonamide | Ki | 1.2 [1] |
 | 5-(4-Chlorophenyl)-4-[3-[4-[4-[[4-[[(2R)-4-(dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonylamino]phenyl]piperazin-1-yl]phenyl]-2-methyl-1-propan-2-ylpyrrole-3-carboxylic acid | IC50 | 4.8 [1] |
 | 3-(5-(1-(2-(Benzo[d]thiazol-2-yl)hydrazono)ethyl)furan-2-yl)-benzoic acid | IC50 | 2200.0 [1], 15000.0 [2] |
 | 7-[4-[[4-[[(2R)-4-(Dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonylcarbamoyl]-2-methylphenyl]-3-(3-naphthalen-1-yloxypropyl)pyrazolo[1,5-a]pyridine-2-carboxylic acid | IC50 | 4.4 [1] |
 | 3-Methoxy-N,N-dimethyl-4-[4-[[3-nitro-4-(2-phenylsulfanylethylamino)phenyl]sulfonylcarbamoyl]phenyl]benzamide | Ki | 471.0 [1], 10000.0 [2] |
 | 4-(4,4-Dimethylpiperidin-1-yl)-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonylbenzamide | Ki | 1.1 [1], 10000.0 [2] |
 | 4-[4-[2-(Dimethylamino)ethyl]-2-methoxyphenyl]-N-[3-nitro-4-(2-phenylsulfanylethylamino)phenyl]sulfonylbenzamide | Ki | 665.0 [1], 998.0 [2] |
 | N-[4-[[(2R)-5-(Dimethylamino)-1-phenylsulfanylpentan-2-yl]amino]-3-nitrophenyl]sulfonyl-4-(4,4-dimethylpiperidin-1-yl)benzamide | Ki | 2.6 [1], 728.0 [2] |
 | 4-[2-Methoxy-4-(3-morpholin-4-yl-3-oxopropyl)phenyl]-N-[3-nitro-4-(2-phenylsulfanylethylamino)phenyl]sulfonylbenzamide | Ki | 57.9 [1], 790.0 [2] |
 | 4-[4-(3-Hydroxypropyl)-2-methoxyphenyl]-N-[3-nitro-4-(2-phenylsulfanylethylamino)phenyl]sulfonylbenzamide | Ki | 21.5 [1], 2960.0 [2] |
 | 3-Nitro-4-(2-phenylsulfanylethylamino)-N-(4-piperazin-1-ylbenzoyl)benzenesulfonamide | Ki | 2520.0 [1], 10000.0 [2] |
 | N-(4-Morpholin-4-ylbenzoyl)-3-nitro-4-(2-phenylsulfanylethylamino)benzenesulfonamide | Ki | 1080.0 [1], 10000.0 [2] |
 | N-[4-[[(2R)-4-(Dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonyl-4-[2-methoxy-4-(3-morpholin-4-ylpropyl)phenyl]benzamide | Ki | 0.5 [1], 148.0 [2] |
 | N,N-Dimethyl-4-[4-[[3-nitro-4-(2-phenylsulfanylethylamino)phenyl]sulfonylcarbamoyl]phenyl]piperazine-1-carboxamide | Ki | 294.0 [1], 869.0 [2] |
 | N-[4-[[(2R)-4-(Dimethylamino)-4-oxo-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonyl-4-(4,4-dimethylpiperidin-1-yl)benzamide | Ki | 3.1 [1], 1790.0 [2] |
 | 4-(4,4-Dimethylpiperidin-1-yl)-N-[4-[[(2S)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonylbenzamide | Ki | 75.0 [1], 6050.0 [2] |
 | 4-[4-[2-(Dimethylamino)-2-oxoethyl]-2-methoxyphenyl]-N-[3-nitro-4-(2-phenylsulfanylethylamino)phenyl]sulfonylbenzamide | Ki | 251.0 [1], 10000.0 [2] |
 | N-[4-[[(2R)-6-Amino-1-phenylsulfanylhexan-2-yl]amino]-3-nitrophenyl]sulfonyl-4-[2-methoxy-4-(3-morpholin-4-ylpropyl)phenyl]benzamide | Ki | 0.8 [1], 29.6 [2] |
 | 4-[4-[(Dimethylamino)methyl]-2-methoxyphenyl]-N-[3-nitro-4-(2-phenylsulfanylethylamino)phenyl]sulfonylbenzamide | Ki | 426.0 [1], 1000.0 [2] |
 | N-[4-[[(2S)-4-(Dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonyl-4-(4,4-dimethylpiperidin-1-yl)benzamide | Ki | 252.0 [1], 3850.0 [2] |
 | N-[4-[[(2S)-4-(Dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonyl-4-[2-methoxy-4-(3-morpholin-4-ylpropyl)phenyl]benzamide | Ki | 250.0 [1], 1140.0 [2] |
 | 4-(4-Acetylpiperazin-1-yl)-N-[3-nitro-4-(2-phenylsulfanylethylamino)phenyl]sulfonylbenzamide | Ki | 894.0 [1], 2970.0 [2] |
 | N-[4-[[(2R)-4-(Dimethylamino)-4-oxo-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonyl-4-[2-methoxy-4-(3-morpholin-4-ylpropyl)phenyl]benzamide | Ki | 1.7 [1], 1000.0 [2] |
 | 4-(4,4-Dimethylpiperidin-1-yl)-N-[3-nitro-4-(2-phenylsulfanylethylamino)phenyl]sulfonylbenzamide | Ki | 19.0 [1], 652.0 [2] |
 | N-[4-[[(2R)-6-(Dimethylamino)-1-phenylsulfanylhexan-2-yl]amino]-3-nitrophenyl]sulfonyl-4-[2-methoxy-4-(3-morpholin-4-ylpropyl)phenyl]benzamide | Ki | 0.5 [1], 215.0 [2] |
 | 4-[4-[3-(Dimethylamino)-3-oxopropyl]-2-methoxyphenyl]-N-[3-nitro-4-(2-phenylsulfanylethylamino)phenyl]sulfonylbenzamide | Ki | 38.9 [1], 1000.0 [2] |
 | N-[4-[[(2R)-6-Amino-1-phenylsulfanylhexan-2-yl]amino]-3-nitrophenyl]sulfonyl-4-(4,4-dimethylpiperidin-1-yl)benzamide | Ki | 1.0 [1], 256.0 [2] |
 | 4-[2-Methoxy-4-(3-morpholin-4-ylpropyl)phenyl]-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonylbenzamide | Ki | 0.5 [1], 10000.0 [2] |
 | Tert-butyl 4-[4-[[3-nitro-4-(2-phenylsulfanylethylamino)phenyl]sulfonylcarbamoyl]phenyl]piperazine-1-carboxylate | Ki | 396.0 [1], 3350.0 [2] |
 | N-[4-[[(2R)-5-(Dimethylamino)-1-phenylsulfanylpentan-2-yl]amino]-3-nitrophenyl]sulfonyl-4-[2-methoxy-4-(3-morpholin-4-ylpropyl)phenyl]benzamide | Ki | 0.9 [1], 71.0 [2] |
 | N-[4-[[(2R)-6-(Dimethylamino)-1-phenylsulfanylhexan-2-yl]amino]-3-nitrophenyl]sulfonyl-4-(4,4-dimethylpiperidin-1-yl)benzamide | Ki | 1.2 [1], 174.0 [2] |
 | 4-[4-[[2-(4-Chlorophenyl)-6-[2-(dimethylamino)-2-oxoethoxy]phenyl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide | IC50 | 10.0 [1], 226.0 [2] |
 | 4-[4-[[2-(4-Chlorophenyl)-5-[2-(dimethylamino)-2-oxoethoxy]phenyl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide | IC50 | 10.0 [1], 2090.0 [2] |
 | 4-[4-[[2-(4-Chlorophenyl)-5-[2-(dimethylamino)ethoxy]phenyl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide | IC50 | 10.0 [1], 138.0 [2] |
 | 2-[4-[[2-(4-Chlorophenyl)phenyl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylpyrimidine-5-carboxamide | IC50 | 39.0 [1], 2090.0 [2] |
 | 4-[4-[(R)-[2-(4-Chlorophenyl)phenyl]sulfinyl]piperidin-1-yl]-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide | IC50 | 11.0 [1], 1720.0 [2] |
 | 4-[4-[[2-(4-Chlorophenyl)phenyl]methyl]-4-cyanopiperidin-1-yl]-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide | IC50 | 10.0 [1], 2820.0 [2] |
 | N-[2-(4-Ethylphenyl)ethyl]-6-[5-[2-(4-ethylphenyl)ethylcarbamoyl]-3-methyl-1,4,6,7-tetraoxonaphthalen-2-yl]-2,3,5,8-tetrahydroxy-7-methylnaphthalene-1-carboxamide | IC50 | 240.0 [1] |
| N-[2-(4-Ethylphenyl)ethyl]-6-[5-[2-(4-ethylphenyl)ethylcarbamoyl]-3-methyl-1,4,6,7-tetraoxonaphthalen-2-yl]-2,3,5,8-tetrahydroxy-7-methylnaphthalene-1-carboxamide | Ki | 160.0 [1] |
 | 3-Methyl-5-(2-phenylacetyl)-2-[1,4,6,7-tetrahydroxy-3-methyl-5-(2-phenylacetyl)naphthalen-2-yl]naphthalene-1,4,6,7-tetrone | IC50 | 340.0 [1] |
| 3-Methyl-5-(2-phenylacetyl)-2-[1,4,6,7-tetrahydroxy-3-methyl-5-(2-phenylacetyl)naphthalen-2-yl]naphthalene-1,4,6,7-tetrone | Ki | 240.0 [1] |
 | 2,3,5,8-Tetrahydroxy-7-methyl-6-[3-methyl-1,4,6,7-tetraoxo-5-(2-phenylpropylcarbamoyl)naphthalen-2-yl]-N-(2-phenylpropyl)naphthalene-1-carboxamide | IC50 | 320.0 [1] |
| 2,3,5,8-Tetrahydroxy-7-methyl-6-[3-methyl-1,4,6,7-tetraoxo-5-(2-phenylpropylcarbamoyl)naphthalen-2-yl]-N-(2-phenylpropyl)naphthalene-1-carboxamide | Ki | 210.0 [1] |
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