Anti-estrogen binding site (AEBS) Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Doxorubicin	IC50	150.0 [1], 200.0 [2], 300.0 [3]
	2-Hydroxy-N-[[[(2S,3S,4S,6R)-3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]amino]methyl]benzamide	IC50	50.0 [1], 70.0 [2], 80.0 [3]
	2-Hydroxy-N-[[[(2S,3S,4S,6R)-3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]amino]methyl]-5-[(E)-2-[2-[2-[2-[4-[(E)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl]phenoxy]ethyl-methylamino]ethoxy]ethoxy]ethoxyiminomethyl]benzamide	IC50	30.0 [1], 40.0 [2]
	Tamoxifen	IC50	12.0 [1]
	Epipachysamine D	IC50	20000.0 [1]
	Axillaridine A	IC50	8000.0 [1]
	Pachyaximine A	IC50	400.0 [1]
	4-(2-Chloro-1-(4-(2-(diethylamino)ethoxy)phenyl)-2-phenylethenyl)-2-methoxyphenol	IC50	22.0 [1]
	4-(1-Chloro-2-(4-(2-(diethylamino)ethoxy)phenyl)-2-phenylethenyl)-2-methoxyphenol	IC50	32.0 [1]
	Pachysamine B	IC50	600.0 [1]
	Spiropachysine	IC50	7400.0 [1]
	(3R)-1-[(5R,8S,9S,10R,13S,14S,17S)-17-[(1S)-1-(Dimethylamino)ethyl]-10,13-dimethyl-4-oxo-1,5,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-yl]-3-propan-2-ylazetidin-2-one	IC50	2800.0 [1]
	(3R)-1-[(5R,8R,9S,10R,13S,14S,16S,17S)-17-[(1S)-1-(Dimethylamino)ethyl]-16-hydroxy-10,13-dimethyl-4-oxo-1,5,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-yl]-3-propan-2-ylazetidin-2-one	IC50	3500.0 [1]
	[(4R,5R,8S,9S,10R,13S,14S,17S)-3-Benzamido-17-[(1S)-1-(dimethylamino)ethyl]-10,13-dimethyl-4,5,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-4-yl] acetate	IC50	600.0 [1]
	[(2R,3S,4R,5R,8S,9S,10R,13S,14S,17S)-17-[(1S)-1-(Dimethylamino)ethyl]-3-(1,3-dioxoisoindol-2-yl)-2-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-4-yl] acetate	IC50	6800.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 15 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Anti-estrogen binding site (AEBS) Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Dec. 2024, https://www.aatbio.com/data-sets/anti-estrogen-binding-site-aebs-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, December 21). Quest Database™ Anti-estrogen binding site (AEBS) Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/anti-estrogen-binding-site-aebs-inhibitors-ic50-ki.
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