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Anoctamin-1 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
MonnaIC5080.0 [1], 1600.0 [2]
N-Phenyl-2-[(trifluoroacetyl)amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC50130.0 [1], 300.0 [2]
TMEM16A Inhibitor C10bmIC5030.0 [1], 83.0 [2]
2-[(2-Chloro-2,2-difluoroacetyl)amino]-N-(2-methylphenyl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC50180.0 [1], 230.0 [2]
2-[(2,2-Difluoro-2-iodoacetyl)amino]-N-(2-methylphenyl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC50600.0 [1], 730.0 [2]
2-[(2,2-Difluoro-2-iodoacetyl)amino]-N-(4-fluorophenyl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC50150.0 [1], 600.0 [2]
2-(4-Chloro-2-methylphenoxy)-N-[(E)-(2-methoxyphenyl)methylideneamino]acetamideIC5077.0 [1], 110.0 [2]
T16AInh-A01IC501000.0 [1]
CaCCinh-A01IC502100.0 [1]
N-(2-Methylphenyl)-2-[(2,2,2-trifluoroacetyl)amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC50260.0 [1]
N-(2-Chlorophenyl)-2-[(trifluoroacetyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamideIC501300.0 [1]
2-[(2,2,2-Trifluoroacetyl)amino]-N-[4-(trifluoromethyl)phenyl]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC505000.0 [1]
N-Phenyl-2-[(2,2,2-trifluoroacetyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamideIC50370.0 [1]
N-(4-Methylphenyl)-2-[(2,2,2-trifluoroacetyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamideIC50220.0 [1]
N-(2-Chlorophenyl)-2-[(2,2,2-trifluoroacetyl)amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC50660.0 [1]
N-(4-Methylphenyl)-2-[(2,2,2-trifluoroacetyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxamideIC505000.0 [1]
2-[(2,2-Difluoro-2-iodoacetyl)amino]-N-phenyl-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC50230.0 [1]
N-(2-Methylphenyl)-2-(2,2,3,3,3-pentafluoropropanoylamino)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC501300.0 [1]
N-(2-Methylphenyl)-2-[(2,2,2-trifluoroacetyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamideIC5020000.0 [1]
N-(4-Methylphenyl)-2-[(2,2,2-trifluoroacetyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamideIC502500.0 [1]
N-(2-Methylphenyl)-2-(propanoylamino)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamideIC5020000.0 [1]
N-(2-Methylphenyl)-2-(2,2,3,3,3-pentafluoropropanoylamino)-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxamideIC501600.0 [1]
N-(2-Methylphenyl)-2-(propanoylamino)-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxamideIC503000.0 [1]
2-(2,2,3,3,4,4,4-Heptafluorobutanoylamino)-N-(2-methylphenyl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC50380.0 [1]
N-(2-Methylphenyl)-2-(2,2,3,3,3-pentafluoropropanoylamino)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamideIC506200.0 [1]
2-(2,2,3,3,3-Pentafluoropropanoylamino)-N-phenyl-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC502500.0 [1]
2-Acetamido-N-phenyl-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC5020000.0 [1]
2-[(2,2-Difluoro-2-iodoacetyl)amino]-N-[2-(trifluoromethoxy)phenyl]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamideIC501880.0 [1]
2-[(2-Chloro-2,2-difluoroacetyl)amino]-N-(4-fluorophenyl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC50840.0 [1]
2-(2,2,3,3,3-Pentafluoropropanoylamino)-N-[2-(trifluoromethoxy)phenyl]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC502700.0 [1]
2-(Propanoylamino)-N-[2-(trifluoromethoxy)phenyl]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC5020000.0 [1]
N-(2-Chlorophenyl)-2-(2,2,3,3,3-pentafluoropropanoylamino)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC5020000.0 [1]
N-(2-Chlorophenyl)-2-[(2,2,2-trifluoroacetyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxamideIC501300.0 [1]
N-(2-Fluorophenyl)-2-[(2,2,2-trifluoroacetyl)amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC501300.0 [1]
2-Acetamido-N-[2-(trifluoromethoxy)phenyl]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC5020000.0 [1]
2-[(2-Bromo-2,2-difluoroacetyl)amino]-N-(4-fluorophenyl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC50450.0 [1]
N-(4-Fluorophenyl)-2-[(2,2,2-trifluoroacetyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamideIC50490.0 [1]
2-[(2-Chloro-2,2-difluoroacetyl)amino]-N-[2-(trifluoromethoxy)phenyl]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamideIC5020000.0 [1]
2-[(2-Bromo-2,2-difluoroacetyl)amino]-N-phenyl-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC50230.0 [1]
2-[(2,2,2-Trifluoroacetyl)amino]-N-[2-(trifluoromethoxy)phenyl]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamideIC50370.0 [1]
N-(4-Fluorophenyl)-2-[(2,2,2-trifluoroacetyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxamideIC503800.0 [1]
2-[(2-Bromo-2,2-difluoroacetyl)amino]-N-[2-(trifluoromethoxy)phenyl]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamideIC50700.0 [1]
2-[(2,2,2-Trifluoroacetyl)amino]-N-[2-(trifluoromethoxy)phenyl]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC501300.0 [1]
N-(2-Ethylphenyl)-2-[(2,2,2-trifluoroacetyl)amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC501300.0 [1]
2-[(2-Chloro-2,2-difluoroacetyl)amino]-N-phenyl-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC50925.0 [1]
N-(4-Fluorophenyl)-2-[(2,2,2-trifluoroacetyl)amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC50320.0 [1]
N-(3-Chlorophenyl)-2-[(2,2,2-trifluoroacetyl)amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC505000.0 [1]
N-(4-Chlorophenyl)-2-[(2,2,2-trifluoroacetyl)amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC503000.0 [1]
2-(Acetylamino)-N-(2-methylphenyl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC5010000.0 [1]
N-(2-Methylphenyl)-2-[(trifluoroacetyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamideIC50170.0 [1]
N-Phenyl-2-(propanoylamino)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC501200.0 [1]
N-(2-Methylphenyl)-2-(propanoylamino)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamideIC5020000.0 [1]
5-[(3-Iodophenyl)methoxy]-2-(4-methoxyphenyl)-1-benzofuran-3-carboxylic acidIC505900.0 [1]
5-[(3,4-Difluorophenyl)methoxy]-2-(4-methoxyphenyl)-1-benzofuran-3-carboxylic acidIC5023500.0 [1]
5-[(3-Chlorophenyl)methoxy]-2-(4-methylphenyl)-1-benzofuran-3-carboxylic acidIC5013300.0 [1]
5-[(2-Bromophenyl)methoxy]-2-(4-methylphenyl)-1-benzofuran-3-carboxylic acidIC506300.0 [1]
5-[(2,6-Difluorophenyl)methoxy]-2-(4-methylphenyl)-1-benzofuran-3-carboxylic acidIC5023000.0 [1]
2-Naphthalen-2-yl-5-[[3-(trifluoromethyl)phenyl]methoxy]-1-benzofuran-3-carboxylic acidIC5010400.0 [1]
5-[(4-Fluorophenyl)methoxy]-2-naphthalen-2-yl-1-benzofuran-3-carboxylic acidIC503200.0 [1]
5-[(2-Bromophenyl)methoxy]-2-(4-methoxyphenyl)-1-benzofuran-3-carboxylic acidIC5011200.0 [1]
5-[(3-Iodophenyl)methoxy]-2-(4-methylphenyl)-1-benzofuran-3-carboxylic acidIC5010800.0 [1]
5-[(4-Bromophenyl)methoxy]-2-(4-methylphenyl)-1-benzofuran-3-carboxylic acidIC503300.0 [1]
2-(4-Methylphenyl)-5-[[3-(trifluoromethyl)phenyl]methoxy]-1-benzofuran-3-carboxylic acidIC5013100.0 [1]
5-[(4-Bromophenyl)methoxy]-2-naphthalen-2-yl-1-benzofuran-3-carboxylic acidIC504900.0 [1]
5-[(2,6-Difluorophenyl)methoxy]-2-naphthalen-2-yl-1-benzofuran-3-carboxylic acidIC502800.0 [1]
5-[(3-Fluorophenyl)methoxy]-2-(4-methoxyphenyl)-1-benzofuran-3-carboxylic acidIC5028700.0 [1]
2-(4-Methoxyphenyl)-5-[(3-phenylphenyl)methoxy]-1-benzofuran-3-carboxylic acidIC5025900.0 [1]
5-[(3,4-Difluorophenyl)methoxy]-2-(4-methylphenyl)-1-benzofuran-3-carboxylic acidIC509000.0 [1]
5-[(4-Fluorophenyl)methoxy]-2-(4-methylphenyl)-1-benzofuran-3-carboxylic acidIC5017300.0 [1]
5-[(3-Chlorophenyl)methoxy]-2-naphthalen-2-yl-1-benzofuran-3-carboxylic acidIC507700.0 [1]
5-[(3,4-Difluorophenyl)methoxy]-2-naphthalen-2-yl-1-benzofuran-3-carboxylic acidIC503200.0 [1]
5-[(2-Bromophenyl)methoxy]-2-naphthalen-2-yl-1-benzofuran-3-carboxylic acidIC505200.0 [1]
5-[(2,6-Difluorophenyl)methoxy]-2-(4-methoxyphenyl)-1-benzofuran-3-carboxylic acidIC5027000.0 [1]
5-[(4-Bromophenyl)methoxy]-2-(4-methoxyphenyl)-1-benzofuran-3-carboxylic acidIC5016300.0 [1]
5-[(3-Chlorophenyl)methoxy]-2-(4-methoxyphenyl)-1-benzofuran-3-carboxylic acidIC5029200.0 [1]
5-[(4-Fluorophenyl)methoxy]-2-(4-methoxyphenyl)-1-benzofuran-3-carboxylic acidIC5021200.0 [1]
5-[(3-Fluorophenyl)methoxy]-2-(4-methylphenyl)-1-benzofuran-3-carboxylic acidIC5015600.0 [1]
2-(4-Methylphenyl)-5-[(3-phenylphenyl)methoxy]-1-benzofuran-3-carboxylic acidIC5016300.0 [1]
5-[(3-Fluorophenyl)methoxy]-2-naphthalen-2-yl-1-benzofuran-3-carboxylic acidIC503800.0 [1]
2-Naphthalen-2-yl-5-[(3-phenylphenyl)methoxy]-1-benzofuran-3-carboxylic acidIC5026900.0 [1]
5-[(3-Iodophenyl)methoxy]-2-naphthalen-2-yl-1-benzofuran-3-carboxylic acidIC5012300.0 [1]
2-Acetamido-N-(2-methylphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamideIC5020000.0 [1]
Items per page: 1 - 10 of 82
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References

This online tool may be cited as follows

MLA

"Quest Database™ Anoctamin-1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Nov. 2024, https://www.aatbio.com/data-sets/anoctamin-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, November 20). Quest Database™ Anoctamin-1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/anoctamin-1-inhibitors-ic50-ki.
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