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Anandamide amidohydrolase Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
3'-Carbamoyl-[1,1'-biphenyl]-3-yl cyclohexylcarbamateIC5015.0 [1]
CID 10427006IC5010.0 [1]
CID 10427006Ki9.0 [1]
1-([1,3]Oxazolo[4,5-b]pyridin-2-yl)-7-phenylheptan-1-oneIC5012.0 [1]
1-([1,3]Oxazolo[4,5-b]pyridin-2-yl)-7-phenylheptan-1-oneKi0.28 [1]
Oleyl trifluoromethyl ketoneIC50187.0 [1], 600.0 [2], 4500.0 [3], 9900.0 [4]
Oleyl trifluoromethyl ketoneKi1.2 [1], 12.0 [2], 250.0 [3]
1-Piperazinecarboxamide, N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)-IC5033.0 [1]
N-Phenyl-4-(quinolin-3-ylmethyl)piperidine-1-carboxamideIC5016.2 [1]
1-Oxazolo[4,5-b]pyridin-2-yl-6-phenyl-hexan-1-oneIC501.0 [1]
1-Oxazolo[4,5-b]pyridin-2-yl-6-phenyl-hexan-1-oneKi0.09 [1], 0.2 [2]
4-Nitrophenyl 4-[bis(2H-1,3-benzodioxol-5-yl)(hydroxy)methyl]piperidine-1-carboxylateIC504000.0 [1]
Benzyl N-[4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3-yl)-2-methylphenyl]carbamateIC5013.0 [1]
(R)-Octan-2-yl 4-bromo-3-oxobutanoateIC502600.0 [1], 3100.0 [2]
(R)-Octan-2-yl 4-bromo-3-oxobutanoateKi800.0 [1]
(2R)-2-(3-Fluoro-4-phenylphenyl)-N-(3-methylpyridin-2-yl)propanamideIC502000.0 [1]
N-Phenyl-4-(quinolin-2-ylmethyl)piperazine-1-carboxamideIC5023.0 [1], 33.0 [2], 350.0 [3], 991.0 [4]
Oleoyl oxazolopyridineIC5040.0 [1]
Oleoyl oxazolopyridineKi2.3 [1], 13.0 [2]
1-(5-(Pyridin-2-yl)oxazol-2-yl)octadec-9-en-1-oneIC50150.0 [1], 200.0 [2]
1-(5-(Pyridin-2-yl)oxazol-2-yl)octadec-9-en-1-oneKi3.0 [1], 10.0 [2]
6-[2-(7-Phenylheptanoyl)-1,3-oxazol-5-yl]pyridine-2-carboxylic acidIC50100.0 [1]
6-[2-(7-Phenylheptanoyl)-1,3-oxazol-5-yl]pyridine-2-carboxylic acidKi10.4 [1], 20.0 [2], 26.0 [3]
FAAH inhibitor 1IC5011.0 [1], 18.0 [2], 19.0 [3], 20.0 [4], 34.0 [5]
N,N-Dimethyl-5-[(4-phenylphenyl)methyl]-1-tetrazolecarboxamideIC5012.0 [1], 37.3 [2], 38.02 [3]
Methoxy arachidonyl fluorophosphonateIC500.33 [1], 1.0 [2], 3.0 [3]
1-(Oxazol-2-yl)-7-phenylheptan-1-oneIC5043.0 [1], 2500.0 [2]
1-(Oxazol-2-yl)-7-phenylheptan-1-oneKi48.0 [1]
1-(Oxazol-2-yl)octadec-9-en-1-oneIC502000.0 [1]
1-(Oxazol-2-yl)octadec-9-en-1-oneKi45.0 [1], 100.0 [2]
7-Phenyl-1-(5-phenyloxazol-2-yl)heptan-1-oneKi80.0 [1]
1,1,1-Trifluorononan-2-oneIC5030000.0 [1]
1,1,1-Trifluorononan-2-oneKi1200.0 [1]
1,1,1-Trifluorotridecan-2-oneIC5010000.0 [1]
1,1,1-Trifluorotridecan-2-oneKi140.0 [1]
1,1,1-Trifluoro-9-phenyl-nonan-2-oneIC502000.0 [1]
1,1,1-Trifluoro-9-phenyl-nonan-2-oneKi25.0 [1]
3-(4-Phenylphenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]propan-1-oneKi0.75 [1], 2.9 [2]
4-[[3-(4-Chlorophenoxy)phenyl]methyl]-N-phenylpiperazine-1-carboxamideIC506.0 [1], 9.0 [2]
4-Bromo-3-oxo-butyric acid (Z)-tetradec-5-enyl esterIC50600.0 [1], 2500.0 [2]
4-Bromo-3-oxo-butyric acid (Z)-tetradec-5-enyl esterKi190.0 [1]
Ethyl 1-(4-chlorophenyl)-5-[3-(cyclohexylcarbamoyloxy)phenyl]pyrazole-3-carboxylateIC5015.0 [1], 17.0 [2], 18.0 [3]
AnandamideIC503400.0 [1], 4100.0 [2]
AnandamideKi10000.0 [1]
Aacocf3IC5012.3 [1], 3000.0 [2]
t-TUCBIC50140.0 [1], 260.0 [2], 2800.0 [3]
(Z)-1-(Benzo[d]oxazol-2-yl)octadec-9-en-1-oneIC5010000.0 [1]
(Z)-1-(Benzo[d]oxazol-2-yl)octadec-9-en-1-oneKi73.0 [1]
7-Phenyl-1-[5-(Pyridin-2-Yl)-1,3,4-Oxadiazol-2-Yl]heptan-1-OneIC501.0 [1]
7-Phenyl-1-[5-(Pyridin-2-Yl)-1,3,4-Oxadiazol-2-Yl]heptan-1-OneKi0.29 [1], 1.2 [2]
2-(7-Phenylheptanoyl)oxazole-5-carbonitrileIC506.5 [1]
2-(7-Phenylheptanoyl)oxazole-5-carbonitrileKi0.4 [1], 1.0 [2]
2-Nonadecanone, 1,1,1-trifluoro-IC506400.0 [1]
2-Nonadecanone, 1,1,1-trifluoro-Ki240.0 [1]
1,1,1-Trifluoro-8-phenyl-octan-2-oneIC505000.0 [1]
1,1,1-Trifluoro-8-phenyl-octan-2-oneKi100.0 [1]
1,1,1-Trifluoro-undecan-2-oneIC5010000.0 [1]
1,1,1-Trifluoro-undecan-2-oneKi130.0 [1]
1-(Oxazolo[4,5-b]pyridin-2-yl)-8-phenyloctan-1-oneIC500.3 [1]
1-(Oxazolo[4,5-b]pyridin-2-yl)-8-phenyloctan-1-oneKi0.39 [1]
1-(Oxazolo[4,5-b]pyridin-2-yl)-9-phenylnonan-1-oneIC500.1 [1]
1-(Oxazolo[4,5-b]pyridin-2-yl)-9-phenylnonan-1-oneKi0.52 [1]
2-(7-Phenylheptanoyl)oxazole-5-carboxylic acidIC50970.0 [1]
2-(7-Phenylheptanoyl)oxazole-5-carboxylic acidKi30.0 [1], 32.0 [2]
1-Piperazinecarboxamide, 4-((3-(4-chlorophenoxy)phenyl)methyl)-N-3-pyridinyl-IC501.4 [1]
Carbamic acid,N-[6-(2-methyl-4,5-diphenyl-1H-imidazol-1-yl)hexyl]-,2-fluorophenyl esterIC501.7 [1], 2.0 [2]
3-(4-(Phenoxymethyl)phenyl)-1-(5-(pyridin-2-yl)oxazol-2-yl)propan-1-oneKi1.0 [1], 5.0 [2]
2-(3-(Biphenyl-4-yl)propanoyl)oxazole-5-carbonitrileKi0.2 [1], 0.26 [2]
[3-[(S)-(4-Chlorophenyl)-(2-chloropyridin-3-yl)methoxy]azetidin-1-yl]-piperidin-1-ylmethanoneIC5078.0 [1], 140.0 [2], 973.0 [3]
[(1R)-1-[(3S)-2-Oxo-1-pent-4-enoylazetidin-3-yl]ethyl] 4-phenylbutanoateIC505.32 [1], 5.37 [2]
4-[(3-Phenoxyphenyl)methyl]-N-phenylpiperazine-1-carboxamideIC5074.0 [1], 80.0 [2], 3020.0 [3]
3'-Carbamoyl-biphenyl-3-yl-hexylphenylcarbamateIC5014.0 [1], 36.0 [2]
[3-[(R)-(4-Chlorophenyl)-(2-chloropyridin-3-yl)methoxy]azetidin-1-yl]-piperidin-1-ylmethanoneIC5010000.0 [1], 500000.0 [2]
4-[(5-Bromo-2-hydroxy-3-methoxyphenyl)methyl]-N-phenylpiperazine-1-carboxamideIC50120.0 [1], 130.0 [2], 210.0 [3]
N-(3-Methylpyridin-2-yl)-2-[4-[[2-(trifluoromethyl)pyridin-4-yl]amino]phenyl]propanamideIC501900.0 [1], 2200.0 [2], 2500.0 [3]
4-Bromo-3-oxo-butyric acid heptyl esterIC501500.0 [1], 2100.0 [2]
4-Bromo-3-oxo-butyric acid heptyl esterKi550.0 [1]
(Z)-1-Bromo-nonadec-10-en-2-oneIC501000.0 [1], 5300.0 [2]
(Z)-1-Bromo-nonadec-10-en-2-oneKi390.0 [1]
4-Chloro-3-oxo-butyric acid (R)-1-methyl-heptyl esterIC50700.0 [1], 2900.0 [2]
4-Chloro-3-oxo-butyric acid (R)-1-methyl-heptyl esterKi1100.0 [1]
4-[(1-Hydroxynaphthalen-2-yl)methyl]-N-phenylpiperazine-1-carboxamideIC5016.0 [1], 21.0 [2], 50.0 [3]
4-[(5-Bromo-2-hydroxyphenyl)methyl]-N-phenylpiperazine-1-carboxamideIC50290.0 [1], 330.0 [2], 410.0 [3]
4-[(2-Hydroxyphenyl)methyl]-N-phenylpiperazine-1-carboxamideIC501300.0 [1], 3000.0 [2], 10000.0 [3]
4-[(2,2-Difluoro-1,3-benzodioxol-5-yl)methyl]-N-phenylpiperazine-1-carboxamideIC5087.0 [1], 100.0 [2], 290.0 [3]
N-(4-Fluorophenyl)-4-(quinolin-3-ylmethyl)piperazine-1-carboxamideIC50130.0 [1], 220.0 [2], 6500.0 [3]
N-Phenyl-4-[(4-propan-2-ylphenyl)methyl]piperazine-1-carboxamideIC50220.0 [1], 380.0 [2], 10000.0 [3]
4-[(3,4-Dibromophenyl)methyl]-N-phenylpiperazine-1-carboxamideIC5019.0 [1], 38.0 [2], 270.0 [3]
4-(Naphthalen-2-ylmethyl)-N-phenylpiperazine-1-carboxamideIC5017.0 [1], 23.0 [2], 265.0 [3]
CarbarylIC5030000.0 [1]
BenzilIC5040000.0 [1]
AmperozideIC50455.0 [1], 1340.0 [2]
PhenmediphamIC50152.0 [1], 377.0 [2]
Cyclohexyl biphenyl-3-ylcarbamateIC505650.0 [1], 5754.4 [2]
Arachidonoyl SerotoninIC5012000.0 [1], 16000.0 [2]
3-Octylthio-1,1,1-trifluoro-2-propanoneIC50230.0 [1], 300.0 [2]
Biphenyl-N-cyclopentyl-carbamateIC5063.0 [1]
4-(1,3-Benzodioxol-5-ylmethyl)-N-phenylpiperazine-1-carboxamideIC501200.0 [1], 8000.0 [2]
CID 76313567IC504800.0 [1]
Farinosone AIC501200.0 [1], 10000.0 [2]



References

This online tool may be cited as follows

MLA

"Quest Database™ Anandamide amidohydrolase Inhibitors (IC50, Ki)." AAT Bioquest, Inc.20 Nov2024https://www.aatbio.com/data-sets/anandamide-amidohydrolase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024November 20). Quest Database™ Anandamide amidohydrolase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/anandamide-amidohydrolase-inhibitors-ic50-ki.
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