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AMP deaminase 3 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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1-Bromo-4-[2-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)ethyl]-5,6,7,8-tetrahydronaphthalene-2-carboxylic acidKi2.0 [1]
4-[2-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)ethyl]-5,6,7,8-tetrahydronaphthalene-2-carboxylic acidKi15.0 [1]
CoformycinKi3000.0 [1]
3-[2-(8-Hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]diazepin-3-yl)-ethyl]-benzoic acidKi500.0 [1]
2-Benzyl-6-(8-hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]diazepin-3-yl)-hexanoic acidKi410.0 [1]
2-[4-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)butyl]-2-[[2-(trifluoromethyl)phenyl]methyl]propanedioic acidKi41.0 [1]
6-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)-2-phenylmethoxycarbonylhexanoic acidKi360.0 [1]
4-[2-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)ethyl]naphthalene-2-carboxylic acidKi20.0 [1]
2-[4-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)butyl]-2-[[3-(trifluoromethyl)phenyl]methyl]propanedioic acidKi29.0 [1]
2-[4-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)butyl]-2-[[4-(trifluoromethyl)phenyl]methyl]propanedioic acidKi40.0 [1]
2-Carbamoyl-6-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)-2-methylhexanoic acidKi7800.0 [1]
Ethyl 4-[2-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)ethyl]-5,6,7,8-tetrahydronaphthalene-2-carboxylateKi1300.0 [1]
Ethyl 4-[2-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)ethyl]-1-methoxy-5,6,7,8-tetrahydronaphthalene-2-carboxylateKi2300.0 [1]
Ethyl 4-[2-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)ethyl]-1-propan-2-yloxy-5,6,7,8-tetrahydronaphthalene-2-carboxylateKi3800.0 [1]
2-Benzyl-2-[4-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)butyl]propanedioic acidKi170.0 [1]
Ethyl 1-bromo-4-[2-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)ethyl]-5,6,7,8-tetrahydronaphthalene-2-carboxylateKi1000.0 [1]
4-[2-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)ethyl]-1-phenylmethoxy-5,6,7,8-tetrahydronaphthalene-2-carboxylic acidKi9.0 [1]
1,3-Dichloro-4-[2-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)ethyl]-5,6,7,8-tetrahydronaphthalene-2-carboxylic acidKi50.0 [1]
6-Bromo-4-[2-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)ethyl]naphthalene-2-carboxylic acidKi960.0 [1]
Ethyl 4-[2-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)ethyl]-1-phenylmethoxy-5,6,7,8-tetrahydronaphthalene-2-carboxylateKi300.0 [1]
2-(Cyclohexylcarbamoyl)-6-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)-2-methylhexanoic acidKi5200.0 [1]
6-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)-2-methyl-2-(2-phenylethylcarbamoyl)hexanoic acidKi2100.0 [1]
Ethyl 4-[2-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)ethyl]-8-(trifluoromethyl)naphthalene-2-carboxylateKi35000.0 [1]
Diethyl 2-benzyl-2-[4-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)butyl]propanedioateKi2600.0 [1]
Dibenzyl 2-[4-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)butyl]-2-[[2-(trifluoromethyl)phenyl]methyl]propanedioateKi250.0 [1]
2-(Benzylcarbamoyl)-6-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)hexanoic acidKi2400.0 [1]
6-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)-2-methyl-2-[[3-(trifluoromethyl)phenyl]methyl]hexanoic acidKi1200.0 [1]
Ethyl 6-bromo-4-[2-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)ethyl]naphthalene-2-carboxylateKi14000.0 [1]
Diethyl 2-[4-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)butyl]-2-methylpropanedioateKi44800.0 [1]
Methyl 4-[2-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)ethyl]naphthalene-2-carboxylateKi1800.0 [1]
4-[2-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)ethyl]-3-methoxy-5,6,7,8-tetrahydronaphthalene-2-carboxylic acidKi40.0 [1]
Ethyl 1,3-dichloro-4-[2-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)ethyl]-5,6,7,8-tetrahydronaphthalene-2-carboxylateKi500.0 [1]
4-[2-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)ethyl]-1-propan-2-yloxy-5,6,7,8-tetrahydronaphthalene-2-carboxylic acidKi90.0 [1]
4-[2-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)ethyl]-1-methoxy-5,6,7,8-tetrahydronaphthalene-2-carboxylic acidKi30.0 [1]
Diethyl 2-[4-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)butyl]-2-[[2-(trifluoromethyl)phenyl]methyl]propanedioateKi360.0 [1]
Ethyl 4-[2-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)ethyl]-3-methoxy-5,6,7,8-tetrahydronaphthalene-2-carboxylateKi2400.0 [1]
Benzyl 4-[2-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)ethyl]-5,6,7,8-tetrahydronaphthalene-2-carboxylateKi5000.0 [1]
6-(8-Hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]diazepin-3-yl)-hexanoic acidKi4200.0 [1]
2-[4-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)butyl]propanedioic acidKi5100.0 [1]
2-[4-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)butyl]-2-methylpropanedioic acidKi6000.0 [1]
6-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)-2-methyl-2-phenylmethoxycarbonylhexanoic acidKi900.0 [1]
4-[2-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)ethyl]-8-(trifluoromethyl)naphthalene-2-carboxylic acidKi220.0 [1]
Benzyl 1,3-dichloro-4-[2-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)ethyl]-5,6,7,8-tetrahydronaphthalene-2-carboxylateKi300.0 [1]
2-[(4-Chlorophenyl)methylcarbamoyl]-6-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)hexanoic acidKi1300.0 [1]
Dibenzyl 2-[4-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)butyl]-2-methylpropanedioateKi5200.0 [1]
3-(2-Imidazo[2,1-f][1,2,4]triazin-7-ylethyl)benzoic acidIC50370000.0 [1]
4-(2-Imidazo[2,1-f][1,2,4]triazin-7-ylethyl)-5,6,7,8-tetrahydronaphthalene-2-carboxylic acidIC50900.0 [1]
Items per page: 1 - 10 of 47
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References

This online tool may be cited as follows

MLA

"Quest Database™ AMP deaminase 3 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/amp-deaminase-3-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ AMP deaminase 3 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/amp-deaminase-3-inhibitors-ic50-ki.
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