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AMP deaminase 2 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
2-Benzyl-6-(8-hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]diazepin-3-yl)-hexanoic acidKi410.0 [1]
6-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)-2,2-diphenylhexanoic acidKi920.0 [1]
3-Propyl-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-8-olKi125000.0 [1]
3-Hexyl-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepine-8-olKi20000.0 [1]
3-(6-Hydroxyhexyl)-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-8-olKi64000.0 [1]
Ethyl 6-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)hexanoateKi44000.0 [1]
2-[(3-Chlorophenyl)methyl]-6-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)hexanoic acidKi1400.0 [1]
2-[(4-Bromophenyl)methyl]-6-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)hexanoic acidKi1100.0 [1]
3-(4-Hydroxybutyl)-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-8-olKi53000.0 [1]
5-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)pentanenitrileKi240000.0 [1]
6-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)-2-phenylhexanoic acidKi2100.0 [1]
2-[(2-Bromophenyl)methyl]-6-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)hexanoic acidKi300.0 [1]
Ethyl 6-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)-2-phenylhexanoateKi9600.0 [1]
Imidazo[4,5-d][1,3]diazepin-8-ol, 3-butyl-3,4,7,8-tetrahydro-Ki84000.0 [1]
2-[4-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)butyl]-1,3-dihydroindene-2-carboxylic acidKi970.0 [1]
3-(3-Hydroxypropyl)-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-8-olKi68000.0 [1]
2-(3-Bromophenyl)-6-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)hexanoic acidKi2400.0 [1]
Ethyl 2-(3-bromophenyl)-6-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)hexanoateKi9700.0 [1]
3-(2-Hydroxyethyl)-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-8-olKi150000.0 [1]
6-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)-2,2-bis(2-methylpropyl)hexanoic acidKi860.0 [1]
Methyl 5-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)pentanoateKi63000.0 [1]
4-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)butanenitrileKi125000.0 [1]
7-(8-Hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]diazepin-3-yl)-heptanoic acid ethyl esterKi55000.0 [1]
6-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)hexylphosphonic acidKi55000.0 [1]
2-[(3-Bromophenyl)methyl]-6-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)hexanoic acidKi790.0 [1]
Ethyl 2-[(3-bromophenyl)methyl]-6-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)hexanoateKi3800.0 [1]
3-[5-(2H-Tetrazol-5-yl)pentyl]-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-8-olKi6000.0 [1]
2-[(3-Bromophenyl)methyl]-6-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)-2-methylhexanoic acidKi640.0 [1]
3-(5-Hydroxypentyl)-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-8-olKi36000.0 [1]
6-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)-2,2-dimethylhexanoic acidKi8200.0 [1]
2-[(4-Chlorophenyl)methyl]-6-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)hexanoic acidKi1700.0 [1]
6-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)hexanamideKi180000.0 [1]
3-Ethyl-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-8-olKi125000.0 [1]
5-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)pentylphosphonic acidKi35000.0 [1]
7-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)heptanoic acidKi10000.0 [1]
6-(8-Hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)hexyl-methoxyphosphinic acidKi140000.0 [1]
Ethyl 2-[(3-bromophenyl)methyl]-6-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)-2-methylhexanoateKi3000.0 [1]
Sodium;5-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)pentanoateKi125000.0 [1]
Sodium;6-(8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl)hexanoateKi4200.0 [1]
3-Benzyl-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-8-olKi125000.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ AMP deaminase 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/amp-deaminase-2-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ AMP deaminase 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/amp-deaminase-2-inhibitors-ic50-ki.
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