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Amiloride-sensitive sodium channel alpha-subunit Inhibitors (IC50, Ki)

Structure
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▼
Compound Name
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▼
Standard Type
▲
▼
Standard Values (in nM)
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▼
AmilorideIC50776.0 [1]
BenzamilIC5066.0 [1]
PhenamilIC50401.0 [1]
552-02 Free baseIC508.0 [1]
3,5-Diamino-6-chloro-N-[N'-[4-[4-(3-hydroxypropoxy)phenyl]butyl]carbamimidoyl]pyrazine-2-carboxamideIC507.0 [1]
3,5-Diamino-6-chloro-N-[N'-[4-[4-[(2R)-2,3-dihydroxypropoxy]phenyl]butyl]carbamimidoyl]pyrazine-2-carboxamideIC509.0 [1]
1-(4-(4-Aminophenyl)butyl)-3-(3,5-diamino-2-chloropyrazine-6-carbonyl)guanidineIC5021.0 [1]
3,5-Diamino-6-chloro-N-[N'-[4-[4-(hydroxymethyl)phenyl]butyl]carbamimidoyl]pyrazine-2-carboxamideIC5014.0 [1]
3,5-Diamino-6-chloro-N-[N'-[4-[4-(2-hydroxyethoxy)phenyl]butyl]carbamimidoyl]pyrazine-2-carboxamideIC509.0 [1]
3,5-Diamino-6-chloro-N-[N'-[4-(3,4-dihydroxyphenyl)butyl]carbamimidoyl]pyrazine-2-carboxamideIC5042.0 [1]
1-(3,5-Diamino-2-chloropyrazine-6-carbonyl)-3-(5-(4-hydroxyphenyl)pentyl)guanidineIC5064.0 [1]
3,5-Diamino-6-chloro-N-[N'-(6-phenylhexyl)carbamimidoyl]pyrazine-2-carboxamideIC5058.0 [1]
3,5-Diamino-6-chloro-N-[N'-[5-(4-methoxyphenyl)pentyl]carbamimidoyl]pyrazine-2-carboxamideIC5077.0 [1]
3,5-Diamino-6-chloro-N-[N'-[3-(4-methoxyphenyl)propyl]carbamimidoyl]pyrazine-2-carboxamideIC50124.0 [1]
Methyl 4-[4-[[amino-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]methylidene]amino]butyl]benzoateIC5022.0 [1]
3,5-Diamino-6-chloro-N-[N'-[4-[2-(2,3-dihydroxypropoxy)phenyl]butyl]carbamimidoyl]pyrazine-2-carboxamideIC5028.0 [1]
3,5-Diamino-6-chloro-N-[N'-[4-[2-(2-hydroxyethoxy)phenyl]butyl]carbamimidoyl]pyrazine-2-carboxamideIC5031.0 [1]
3,5-Diamino-6-chloro-N-[N'-[3-(4-methoxyphenoxy)propyl]carbamimidoyl]pyrazine-2-carboxamideIC5025.0 [1]
3,5-Diamino-6-chloro-N-[N'-[4-[3-(2,3-dihydroxypropoxy)phenyl]butyl]carbamimidoyl]pyrazine-2-carboxamideIC5026.0 [1]
2-[4-[4-[[Amino-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]methylidene]amino]butyl]phenoxy]acetic acidIC5048.0 [1]
3,5-Diamino-6-chloro-N-[N'-(4-phenylbutyl)carbamimidoyl]pyrazine-2-carboxamideIC5029.0 [1]
3,5-Diamino-6-chloro-N-[N'-[4-[3-(2-hydroxyethoxy)phenyl]butyl]carbamimidoyl]pyrazine-2-carboxamideIC5017.0 [1]
3-[4-[4-[[Amino-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]methylidene]amino]butyl]phenoxy]propanoic acidIC5020.0 [1]
3,5-Diamino-6-chloro-N-[N'-[4-(2-hydroxyphenyl)butyl]carbamimidoyl]pyrazine-2-carboxamideIC5030.0 [1]
3,5-Diamino-6-chloro-N-(N'-hexylcarbamimidoyl)pyrazine-2-carboxamideIC5087.0 [1]
3,5-Diamino-6-chloro-N-[N'-(2-hydroxyethyl)carbamimidoyl]pyrazine-2-carboxamideIC50107.0 [1]
3,5-Diamino-6-chloro-N-[N'-[2-[(4-methoxyphenyl)methoxy]ethyl]carbamimidoyl]pyrazine-2-carboxamideIC5041.0 [1]
3,5-Diamino-6-chloro-N-[N'-[4-(4-methoxyphenyl)butyl]carbamimidoyl]pyrazine-2-carboxamideIC5015.0 [1]
4-[4-[[Amino-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]methylidene]amino]butyl]benzoic acidIC5051.0 [1]
3,5-Diamino-6-chloro-N-[N'-[4-(3-hydroxyphenyl)butyl]carbamimidoyl]pyrazine-2-carboxamideIC5020.0 [1]
3,5-Diamino-6-chloro-N-(N'-octylcarbamimidoyl)pyrazine-2-carboxamideIC50108.0 [1]
3,5-Diamino-6-chloro-N-[N'-(3-phenylpropyl)carbamimidoyl]pyrazine-2-carboxamideIC5050.0 [1]
3,5-Diamino-6-chloro-N-[N'-[4-[4-[(2S)-2,3-dihydroxypropoxy]phenyl]butyl]carbamimidoyl]pyrazine-2-carboxamideIC507.0 [1]
3,5-Diamino-6-chloro-N-[N'-(5-phenylpentyl)carbamimidoyl]pyrazine-2-carboxamideIC5068.0 [1]
3,5-Diamino-6-chloro-N-[N'-[3-(4-hydroxyphenyl)propyl]carbamimidoyl]pyrazine-2-carboxamideIC5088.0 [1]
3,5-Diamino-6-chloro-N-[N'-(2-phenylethyl)carbamimidoyl]pyrazine-2-carboxamideIC5066.0 [1]
3,5-Diamino-6-chloro-N-[N'-(8-phenyloctyl)carbamimidoyl]pyrazine-2-carboxamideIC50477.0 [1]
(2S,3S,4S,5R)-6-[4-[4-[[Amino-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]methylidene]amino]butyl]phenoxy]-3,4,5-trihydroxyoxane-2-carboxylic acidIC5073.0 [1]
3,5-Diamino-6-chloro-N-[N'-[2-(4-hydroxyphenyl)ethyl]carbamimidoyl]pyrazine-2-carboxamideIC5062.0 [1]
4-[4-[[Amino-[(3,5-diamino-6-chloropyrazine-2-carbonyl)amino]methylidene]amino]butyl]benzenesulfonic acidIC5021.0 [1]
3,5-Diamino-6-chloro-N-[N'-[4-(4-hydroxyphenyl)butyl]carbamimidoyl]pyrazine-2-carboxamideIC5017.0 [1]
3,5-Diamino-6-chloro-N-[N'-[3-(4-hydroxyphenoxy)propyl]carbamimidoyl]pyrazine-2-carboxamideIC5032.0 [1]
Items per page: 1 - 10 of 42
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References

This online tool may be cited as follows

MLA

"Quest Database™ Amiloride-sensitive sodium channel alpha-subunit Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/amiloride-sensitive-sodium-channel-alpha-subunit-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Amiloride-sensitive sodium channel alpha-subunit Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/amiloride-sensitive-sodium-channel-alpha-subunit-inhibitors-ic50-ki.
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