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Amiloride-sensitive cation channel 3 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
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▼
Standard Type
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▼
Standard Values (in nM)
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▼
AmilorideIC504400.0 [1]
Benzo[b]thiophen-2-ylmethanamineIC5097000.0 [1]
1,3-Benzothiazol-2-ylmethylamineIC50363000.0 [1]
2-Amino-6-phenylpyridineIC50763000.0 [1]
(3-Methoxy-pyridin-2-yl)-(6-methyl-pyridin-2-yl)-amineIC50190000.0 [1]
6-(2-Phenylethynyl)naphthalene-2-carboxamidineIC506300.0 [1]
6-Phenylpyrimidin-4-amineIC50130000.0 [1]
CID 11160454IC509000.0 [1]
6-Bromo-1,2,3,4-tetrahydroisoquinolineIC50701000.0 [1]
6-(3,5-Dichlorophenyl)-1,2,3,4-tetrahydroisoquinolineIC503300.0 [1]
2-(3,5-Dichlorophenyl)-1H-indole-5-carboximidamideIC50133000.0 [1]
2-(3-Amino-5-chlorophenyl)-1H-indole-5-carboximidamideIC5095000.0 [1]
2-(3-Fluoro-5-methoxyphenyl)-1H-indole-5-carboximidamideIC50374000.0 [1]
2-(3-(Benzylamino)-5-chlorophenyl)-1H-indole-5-carboximidamideIC5077000.0 [1]
2-Phenylpyridin-4-amineIC506900.0 [1]
(4-(1H-Imidazol-4-YL)phenyl)methanamineIC50160000.0 [1]
3-Amino-5-(biphenyl-3-yl)-N-(diaminomethylene)pyrazine-2-carboxamideIC50490.0 [1]
2-Phenyl-1H-indole-5-carboximidamideIC502765000.0 [1]
3-Amino-6-chloro-N-(diaminomethylene)-5-(naphthalen-2-ylamino)pyrazine-2-carboxamideIC50510.0 [1]
3-Amino-N-(diaminomethylene)-5-(3-(thiophen-3-yl)phenyl)pyrazine-2-carboxamideIC50640.0 [1]
2-(2,3,5-Trichlorophenyl)-1H-indole-5-carboximidamideIC50135000.0 [1]
2-(3-Chloro-5-fluorophenyl)-1H-indole-5-carboximidamideIC50278000.0 [1]
2-(2,6-Dichloropyridin-4-yl)-1H-indole-5-carboximidamideIC50291000.0 [1]
2-(3,5-Dibromophenyl)-1H-indole-5-carboximidamideIC5059000.0 [1]
2-(3-Chloro-5-((phenylamino)methyl)phenyl)-1H-indole-5-carboximidamideIC50114000.0 [1]
2-(3,5-Dichloro-4-cyanophenyl)-1H-indole-5-carboximidamideIC50272000.0 [1]
2-(3-Bromo-5-fluorophenyl)-1H-indole-5-carboximidamideIC5059000.0 [1]
2-(3-Chloro-5-methylphenyl)-1H-indole-5-carboximidamideIC5051000.0 [1]
6-Methyl-N-[4-(6-piperazin-1-ylpyridin-3-yl)phenyl]pyridin-2-amineIC503800.0 [1]
6-[4-(4-Methylpiperazin-1-yl)-3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydroisoquinolineIC503100.0 [1]
[3-Chloro-6-[2-(1,2,3,4-tetrahydroisoquinolin-7-yl)ethynyl]-1-benzothiophen-2-yl]methanamineIC50220.0 [1]
6-Bromo-2-[(5-methoxy-1H-indol-3-yl)methyl]-3,4-dihydro-1H-isoquinolineIC5010900.0 [1]
6-[6-(2-Methylpiperidin-1-yl)pyridin-2-yl]-1,2,3,4-tetrahydroisoquinolineIC501700.0 [1]
4-(6-Bromo-3,4-dihydroisoquinolin-2(1H)-yl)-2-methylquinolineIC5027600.0 [1]
6-(3-(Trifluoromethyl)phenyl)-1,2,3,4-tetrahydroisoquinolineIC507100.0 [1]
2-[(5-Methoxy-1H-indol-3-yl)methyl]-6-[3-(trifluoromethyl)phenyl]-3,4-dihydro-1H-isoquinolineIC50103000.0 [1]
2-Methyl-4-(4-(6-methylpyridin-2-ylamino)phenyl)but-3-yn-2-olIC5017000.0 [1]
4-Amino-N-[2-(4-chlorophenyl)ethyl]-2-propylquinoline-6-carboxamideIC509600.0 [1]
6-(4-(4-Methylpiperazin-1-yl)phenyl)-1,2,3,4-tetrahydroisoquinolineIC5014400.0 [1]
2-Phenyl-6-(pyridin-2-ylmethyl)pyridin-4-amineIC505800.0 [1]
CID 54586726IC5019400.0 [1]
4-(3-(4-Aminopyridin-2-yl)phenyl)but-3-yn-1-olIC502600.0 [1]
2-(3-(Phenylethynyl)phenyl)pyridin-4-amineIC501200.0 [1]
Tert-butyl 7-[2-[2-(aminomethyl)-3-chloro-1-benzothiophen-6-yl]ethynyl]-3,4-dihydro-1H-isoquinoline-2-carboxylateIC5050000.0 [1]
[3-Chloro-6-[2-[2-(2,2,2-trifluoroethyl)-3,4-dihydro-1H-isoquinolin-7-yl]ethynyl]-1-benzothiophen-2-yl]methanamineIC5050000.0 [1]
[3-Chloro-6-[2-(5-pyrrolidin-1-yl-5,6,7,8-tetrahydronaphthalen-1-yl)ethynyl]-1-benzothiophen-2-yl]methanamineIC502500.0 [1]
[6-[2-(2-Benzyl-3,4-dihydro-1H-isoquinolin-7-yl)ethynyl]-3-chloro-1-benzothiophen-2-yl]methanamineIC5017100.0 [1]
6-[2-(2-Methyl-1-propan-2-yl-3,4-dihydro-1H-isoquinolin-7-yl)ethynyl]naphthalene-2-carboximidamideIC50460.0 [1]
[6-(2-Phenylethynyl)naphthalen-2-yl]methanamineIC504800.0 [1]
5-[2-[2-(Aminomethyl)-3-chloro-1-benzothiophen-6-yl]ethynyl]-N,N-diethyl-3,4-dihydro-2H-quinolin-1-amineIC50510.0 [1]
[3-Chloro-6-[2-(2-ethyl-3,4-dihydro-1H-isoquinolin-7-yl)ethynyl]-1-benzothiophen-2-yl]methanamineIC50230.0 [1]
[3-Chloro-6-[2-[2-(2,2-difluoroethyl)-3,4-dihydro-1H-isoquinolin-7-yl]ethynyl]-1-benzothiophen-2-yl]methanamineIC5010200.0 [1]
[3-Chloro-6-[2-(2-propan-2-yl-3,4-dihydro-1H-isoquinolin-7-yl)ethynyl]-1-benzothiophen-2-yl]methanamineIC50310.0 [1]
5-[2-[2-(Aminomethyl)-3-chloro-1-benzothiophen-6-yl]ethynyl]-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-1-amineIC50230.0 [1]
4-[2-[2-(Aminomethyl)-3-chloro-1-benzothiophen-6-yl]ethynyl]-N,N-dimethyl-2,3-dihydro-1H-inden-1-amineIC50190.0 [1]
[3-Chloro-6-(2-phenylethynyl)-1-benzothiophen-2-yl]methanamineIC502800.0 [1]
[3-Chloro-6-[2-(1,2-dimethyl-3,4-dihydro-1H-isoquinolin-7-yl)ethynyl]-1-benzothiophen-2-yl]methanamineIC50270.0 [1]
[3-Chloro-6-[2-(2-methyl-3,4-dihydro-1H-isoquinolin-7-yl)ethynyl]-1-benzothiophen-2-yl]methanamineIC50680.0 [1]
3-Chloro-6-(2-phenylethynyl)-1-benzothiophene-2-carboximidamideIC503400.0 [1]
1-[3-[2-[2-(Aminomethyl)-3-chloro-1-benzothiophen-6-yl]ethynyl]phenyl]-N,N-dimethylethanamineIC504300.0 [1]
4-(1H-Imidazol-4-yl)anilineIC50430000.0 [1]
Items per page: 1 - 10 of 61
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References

This online tool may be cited as follows

MLA

"Quest Database™ Amiloride-sensitive cation channel 3 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/amiloride-sensitive-cation-channel-3-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Amiloride-sensitive cation channel 3 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/amiloride-sensitive-cation-channel-3-inhibitors-ic50-ki.
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