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AAT Bioquest

Alpha-mannosidase 2A1 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
1,4-Dideoxy-1,4-imino-D-ribitolKi1430000.0 [1]
(2R,3R,4S)-2-({[(1R)-2-Hydroxy-1-phenylethyl]amino}methyl)pyrrolidine-3,4-diolKi26930.0 [1]
(3R,4S)-Pyrrolidine-3,4-diolKi530610.0 [1]
(2R,3R,4S)-2-(Benzylamino-methyl)-pyrrolidine-3,4-diolKi152470.0 [1]
(2R,3R,4S)-2-(Aminomethyl)pyrrolidine-3,4-diolKi1310000.0 [1]
(2R,3R,4S)-2-[[[(1R,2S)-2-Hydroxy-1,2-diphenylethyl]amino]methyl]pyrrolidine-3,4-diolKi7770.0 [1]
(2R,3R,4S)-2-({[(1S)-2-Hydroxy-1-phenylethyl]amino}methyl)pyrrolidine-3,4-diolKi29880.0 [1]
(2R,3R,4S)-2-[[[(1S,2R)-2-Hydroxy-1,2-diphenylethyl]amino]methyl]pyrrolidine-3,4-diolKi25900.0 [1]
(2R,3R,4S)-2-[[[(1R)-1-Hydroxyethyl]amino]methyl]pyrrolidine-3,4-diolKi450360.0 [1]
(2R,3R,4S)-2-[[[(1S)-1-Hydroxyethyl]amino]methyl]pyrrolidine-3,4-diolKi683000.0 [1]
(2R,3R,4S)-2-(1,2-Dihydroxyethyl)pyrrolidine-3,4-diolKi229380.0 [1]
(2R,3R,4S)-2-[(Cyclopentylamino)methyl]pyrrolidine-3,4-diolKi332950.0 [1]
(2R,3R,4S)-2-[(Thiophen-2-ylmethylamino)methyl]pyrrolidine-3,4-diolKi232800.0 [1]
(2R,3R,4S)-2-[[[(1R)-2-Methoxy-1-phenylethyl]amino]methyl]pyrrolidine-3,4-diolKi35980.0 [1]
(2R,3R,4S)-2-[[[(1R)-1-Phenyl-2-phenylmethoxyethyl]amino]methyl]pyrrolidine-3,4-diolKi68270.0 [1]
(2R,3R,4S)-2-[[[(1R)-2-[(3-Fluorophenyl)methoxy]-1-phenylethyl]amino]methyl]pyrrolidine-3,4-diolKi9140.0 [1]
(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-[[[(1R)-2-hydroxy-1-phenylethyl]amino]methyl]pyrrolidine-3,4-diolKi11800.0 [1]
2-Bromo-N-[(2R)-2-[[(2R,3R,4S)-3,4-dihydroxypyrrolidin-2-yl]methylamino]-2-phenylethyl]benzamideKi4350.0 [1]
(2R,3R,4S)-2-[(Imidazol-1-ylmethylamino)methyl]pyrrolidine-3,4-diolKi567640.0 [1]
(2R,3R,4S)-2-[(Furan-2-ylmethylamino)methyl]pyrrolidine-3,4-diolKi292020.0 [1]
(2R,3R,4S)-2-[[(1-Benzylpiperidin-4-yl)methylamino]methyl]pyrrolidine-3,4-diolKi43150.0 [1]
N-Benzyl-N-[[[(2R,3R,4S)-3,4-dihydroxypyrrolidin-2-yl]methylamino]methyl]acetamideKi64910.0 [1]
(2R,3R,4S)-2-(2,2-Dihydroxyethyl)pyrrolidine-3,4-diolKi437720.0 [1]
(2R,3R,4S)-2-[[[(1R)-2-[(4-Bromophenoxy)methoxy]-1-phenylethyl]amino]methyl]pyrrolidine-3,4-diolKi15480.0 [1]
(2R,3R,4S)-2-[[[(1R)-2-[(2-Fluorophenoxy)methoxy]-1-phenylethyl]amino]methyl]pyrrolidine-3,4-diolKi11270.0 [1]
(2R,3R,4S)-2-[[[(1R)-2-[(4-Fluorophenoxy)methoxy]-1-phenylethyl]amino]methyl]pyrrolidine-3,4-diolKi6470.0 [1]
(2R,3R,4S)-2-[[[(1R)-2-[(3-Bromophenoxy)methoxy]-1-phenylethyl]amino]methyl]pyrrolidine-3,4-diolKi12810.0 [1]
(2R,3R,4S)-2-[[(1-Hydroxy-1,1-diphenylpropan-2-yl)amino]methyl]pyrrolidine-3,4-diolKi80850.0 [1]
(2R,3R,4S)-2-[(1-Phenylethylamino)methyl]pyrrolidine-3,4-diolKi82350.0 [1]
(2R,3R,4S)-2-(2-Anilinoethyl)pyrrolidine-3,4-diolKi123030.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Alpha-mannosidase 2A1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Nov2024https://www.aatbio.com/data-sets/alpha-mannosidase-2a1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024November 21). Quest Database™ Alpha-mannosidase 2A1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/alpha-mannosidase-2a1-inhibitors-ic50-ki.
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