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Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
1-(1,3-Benzothiazol-2-yl)-3,4-dimethyl-1H-pyrazol-5-olIC5010000.0 [1]
4-Benzyl-5-methyl-2-(6-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-3-oneIC50670.0 [1]
DMT1 blocker 1IC501700.0 [1]
2,3-Bis(4-methylphenyl)-5-methyl-1H-indene-1-oneIC5050000.0 [1]
2-Bromo-3-(4-methoxyphenyl)-5-methylinden-1-oneIC5043170.0 [1]
2-(3,5-Dimethoxyphenyl)-3-(4-methoxyphenyl)-5-(4-methylphenyl)inden-1-oneIC5050000.0 [1]
2-Chloro-3-(4-methoxyphenyl)-5-phenylinden-1-oneIC5050000.0 [1]
2-Bromo-3-(3,5-dimethoxyphenyl)-5-methylinden-1-oneIC5050000.0 [1]
2,3-Bis(3,4-dichlorophenyl)-5-methylinden-1-oneIC5032300.0 [1]
2,3-Bis(3,4-dimethoxyphenyl)-5-phenylinden-1-oneIC5050000.0 [1]
2-Chloro-3-(4-methoxyphenyl)-5-(4-methylphenyl)inden-1-oneIC509800.0 [1]
2,3-Bis(3-methoxyphenyl)-5-phenylinden-1-oneIC5050000.0 [1]
2,3-Bis(3-methoxyphenyl)-5-(4-methylphenyl)inden-1-oneIC5013100.0 [1]
2-(3,5-Dimethoxyphenyl)-3-(4-methoxyphenyl)-5-phenylinden-1-oneIC5050000.0 [1]
2-Bromo-5-methyl-3-naphthalen-1-ylinden-1-oneIC5050000.0 [1]
2,3-Bis(4-methoxyphenyl)-5-phenylinden-1-oneIC5050000.0 [1]
2,3-Bis(4-methoxyphenyl)-5-methylinden-1-oneIC5050000.0 [1]
2,3-Bis(3-methoxyphenyl)-5-methylinden-1-oneIC5050000.0 [1]
3-(3,5-Dimethoxyphenyl)-2-(4-methoxyphenyl)-5-methylinden-1-oneIC5050000.0 [1]
2,3-Bis(3,4-dimethoxyphenyl)-5-(4-methylphenyl)inden-1-oneIC5050000.0 [1]
2-Chloro-3-(4-methoxyphenyl)-5-methylinden-1-oneIC5050000.0 [1]
2-Bromo-5-methyl-3-(4-methylphenyl)inden-1-oneIC5050000.0 [1]
2,3-Bis(3,4-dimethoxyphenyl)-5-methylinden-1-oneIC5050000.0 [1]
2-(3,5-Dimethoxyphenyl)-3-(4-methoxyphenyl)-5-methylinden-1-oneIC5050000.0 [1]
2-Bromo-3-(3,4-dimethoxyphenyl)-5-methylinden-1-oneIC5050000.0 [1]
1-(1H-Benzimidazol-2-yl)-4-(4-tert-butylbenzyl)-3-methyl-1H-pyrazol-5-olIC504100.0 [1]
1-(1H-Benzimidazol-2-yl)-3,4-dimethyl-1H-pyrazol-5-olIC504000.0 [1]
1-(1H-Benzimidazol-2-yl)-4-(2-chlorobenzyl)-3-methyl-1H-pyrazol-5-olIC5010000.0 [1]
1-(1H-Benzimidazol-2-yl)-4-(4-chlorobenzyl)-3-methyl-1H-pyrazol-5-olIC5010000.0 [1]
1-(1H-Benzimidazol-2-yl)-4-(3-chlorobenzyl)-3-methyl-1H-pyrazol-5-olIC50540.0 [1]
2-(1,3-Benzoxazol-2-yl)-4,5-dimethyl-1H-pyrazol-3-oneIC5010000.0 [1]
1-(1H-Benzimidazol-2-yl)-4-benzyl-3-methyl-1H-pyrazol-5-olIC50480.0 [1]
4,5-Dimethyl-2-pyridin-2-yl-1H-pyrazol-3-oneIC5010000.0 [1]
2,3,5-Triphenyl-1H-indene-1-oneIC5050000.0 [1]
3,4-Dimethyl-1-phenyl-3-pyrazolin-5-oneIC5010000.0 [1]
4,5-Dimethyl-2-pyrimidin-2-yl-1H-pyrazol-3-oneIC5010000.0 [1]
1-(1H-Benzimidazol-2-yl)-3-phenyl-1H-pyrazol-5-olIC507200.0 [1]
2-Bromo-5-methyl-3-phenylinden-1-oneIC5050000.0 [1]
5-Methyl-2,3-diphenyl-1H-inden-1-oneIC5050000.0 [1]
1-(1H-Benzimidazol-2-yl)-3-methyl-1H-pyrazol-5-olIC503600.0 [1]
2-[2-(1H-Benzimidazol-2-yl)-5-methyl-3-oxo-1H-pyrazol-4-yl]acetic acidIC5015000.0 [1]
2-(6-Chloro-1H-benzimidazol-2-yl)-4,5-diphenyl-1H-pyrazol-3-oneIC502000.0 [1]
4-Benzyl-2-(6-tert-butyl-1H-benzimidazol-2-yl)-5-methyl-1H-pyrazol-3-oneIC50640.0 [1]
4-[(3,4-Dichlorophenyl)methyl]-5-methyl-2-(6-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-3-oneIC50720.0 [1]
2-(1H-Benzimidazol-2-yl)-4-[(3,4-dichlorophenyl)methyl]-5-methyl-1H-pyrazol-3-oneIC503100.0 [1]
4,5-Dimethyl-2-(4-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-3-oneIC5010000.0 [1]
2-(1H-Benzimidazol-2-yl)-4-[(2,4-dichlorophenyl)methyl]-5-methyl-1H-pyrazol-3-oneIC5010000.0 [1]
2-(1H-Benzimidazol-2-yl)-4-[(4-methoxyphenyl)methyl]-5-methyl-1H-pyrazol-3-oneIC50630.0 [1]
4-Benzyl-5-methyl-2-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-3-oneIC50610.0 [1]
2-(6-Methyl-1H-benzimidazol-2-yl)-4,5-diphenyl-1H-pyrazol-3-oneIC505800.0 [1]
4-[(4-Fluorophenyl)methyl]-5-methyl-2-(6-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-3-oneIC50780.0 [1]
5-Methyl-2-(6-methyl-1H-benzimidazol-2-yl)-4-[(4-phenylphenyl)methyl]-1H-pyrazol-3-oneIC505300.0 [1]
4,5-Dimethyl-2-(1-methylbenzimidazol-2-yl)-1H-pyrazol-3-oneIC5010000.0 [1]
4-Benzyl-5-methyl-2-(6-phenyl-1H-benzimidazol-2-yl)-1H-pyrazol-3-oneIC50810.0 [1]
4-Benzyl-5-methyl-2-(4-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-3-oneIC505900.0 [1]
4-[(4-Chlorophenyl)methyl]-5-methyl-2-(6-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-3-oneIC50750.0 [1]
4-[(4-Tert-butylphenyl)methyl]-5-methyl-2-(6-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-3-oneIC503700.0 [1]
4-Benzyl-5-methyl-2-[6-(4-methylphenyl)-1H-benzimidazol-2-yl]-1H-pyrazol-3-oneIC502100.0 [1]
4,5-Dimethyl-2-(6-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-3-oneIC502600.0 [1]
Methyl 2-[2-(1H-benzimidazol-2-yl)-5-methyl-3-oxo-1H-pyrazol-4-yl]acetateIC504300.0 [1]
2-(1H-Benzimidazol-2-yl)-4-benzyl-5-phenyl-1H-pyrazol-3-oneIC5010000.0 [1]
2-(1H-Benzimidazol-2-yl)-4-[(4-fluorophenyl)methyl]-5-methyl-1H-pyrazol-3-oneIC50600.0 [1]
2-(1H-Benzimidazol-2-yl)-5-methyl-4-[(4-phenylphenyl)methyl]-1H-pyrazol-3-oneIC50720.0 [1]
4-Benzyl-2-(6-chloro-1H-benzimidazol-2-yl)-5-methyl-1H-pyrazol-3-oneIC504500.0 [1]
4-Benzyl-2-[6-(4-chlorophenyl)-1H-benzimidazol-2-yl]-5-methyl-1H-pyrazol-3-oneIC501500.0 [1]
2-(1H-Benzimidazol-2-yl)-5-methyl-4-(naphthalen-2-ylmethyl)-1H-pyrazol-3-oneIC50750.0 [1]
2-(1H-Benzimidazol-2-yl)-4-methyl-5-phenyl-1H-pyrazol-3-oneIC5010000.0 [1]
4-Methyl-2-(6-methyl-1H-benzimidazol-2-yl)-5-phenyl-1H-pyrazol-3-oneIC503300.0 [1]
2-(1H-Benzimidazol-2-yl)-5-methyl-4-[[4-(trifluoromethyl)phenyl]methyl]-1H-pyrazol-3-oneIC50550.0 [1]
4-Benzyl-2-(6-bromo-1H-benzimidazol-2-yl)-5-methyl-1H-pyrazol-3-oneIC50490.0 [1]
4-Benzyl-2-(4,5-dimethyl-1H-benzimidazol-2-yl)-5-methyl-1H-pyrazol-3-oneIC5010000.0 [1]
5-Methyl-2-(6-methyl-1H-benzimidazol-2-yl)-4-[[4-(trifluoromethyl)phenyl]methyl]-1H-pyrazol-3-oneIC50570.0 [1]
4-[(4-Methoxyphenyl)methyl]-5-methyl-2-(6-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-3-oneIC50680.0 [1]
4-[(2-Chlorophenyl)methyl]-5-methyl-2-(6-methyl-1H-benzimidazol-2-yl)-1H-pyrazol-3-oneIC50910.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/alpha-ketoglutarate-dependent-dioxygenase-alkb-homolog-3-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/alpha-ketoglutarate-dependent-dioxygenase-alkb-homolog-3-inhibitors-ic50-ki.
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