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Alpha glucosidase Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
AcarboseIC50101500.0 [1], 320000.0 [2], 442400.0 [3], 707900.0 [4], 817380.0 [5]
4-[(2E)-3,7-Dimethylocta-2,6-dienyl]-1,3,7-trihydroxy-2-(2-hydroxy-3-methylbut-3-enyl)xanthen-9-oneIC504800.0 [1]
4-[(2E)-3,7-Dimethylocta-2,6-dienyl]-1,3,7-trihydroxy-2-(2-hydroxy-3-methylbut-3-enyl)xanthen-9-oneKi4200.0 [1], 6600.0 [2]
1-DeoxynojirimycinIC5039500.0 [1], 192000.0 [2]
alpha-MangostinIC505700.0 [1]
alpha-MangostinKi7300.0 [1]
gamma-MangostinIC501700.0 [1]
gamma-MangostinKi1400.0 [1]
TerphenyllinIC504790.0 [1]
TerphenyllinKi1500.0 [1]
1,3,7-Trihydroxy-2,4-diisoprenylxanthoneIC5025500.0 [1]
1,3,7-Trihydroxy-2,4-diisoprenylxanthoneKi19200.0 [1]
Cochinchinone AIC5017400.0 [1]
Cochinchinone AKi13400.0 [1]
CratoxyloneIC5030700.0 [1]
CratoxyloneKi25100.0 [1]
1,3-Dihydroxy-7-[[(2E)-3,7-dimethyl-6-hydroxy-2,7-octadienyl]oxy]-9H-xanthene-9-oneIC5013700.0 [1]
1,3-Dihydroxy-7-[[(2E)-3,7-dimethyl-6-hydroxy-2,7-octadienyl]oxy]-9H-xanthene-9-oneKi13000.0 [1]
4-[4-(4-Hydroxyphenyl)-2,5-dimethoxy-3-(3-methylbutoxy)phenyl]phenolIC508580.0 [1]
4-[4-(4-Hydroxyphenyl)-2,5-dimethoxy-3-(3-methylbutoxy)phenyl]phenolKi3450.0 [1]
5,9-Dihydroxy-2-(hydroxymethyl)-10-methoxy-1,1-dimethyl-2H-furo[2,3-c]xanthen-6-oneIC5072700.0 [1]
5,9-Dihydroxy-2-(hydroxymethyl)-10-methoxy-1,1-dimethyl-2H-furo[2,3-c]xanthen-6-oneKi33900.0 [1]
5,8-Dihydroxy-2-(2-hydroxy-6-methylhept-5-en-2-yl)-4-(3-methylbut-2-enyl)-1,2-dihydrofuro[2,3-c]xanthen-6-oneIC5016100.0 [1]
5,8-Dihydroxy-2-(2-hydroxy-6-methylhept-5-en-2-yl)-4-(3-methylbut-2-enyl)-1,2-dihydrofuro[2,3-c]xanthen-6-oneKi9900.0 [1]
1,3,7-Trihydroxy-4-(2-hydroxy-7-methyl-3-methylideneoct-6-enyl)-2-(3-methylbut-2-enyl)xanthen-9-oneIC5010100.0 [1]
1,3,7-Trihydroxy-4-(2-hydroxy-7-methyl-3-methylideneoct-6-enyl)-2-(3-methylbut-2-enyl)xanthen-9-oneKi8200.0 [1]
3-[(2E)-3,7-Dimethylocta-2,6-dienoxy]-1,7-dihydroxy-2-(3-methylbut-2-enyl)xanthen-9-oneIC5028400.0 [1]
3-[(2E)-3,7-Dimethylocta-2,6-dienoxy]-1,7-dihydroxy-2-(3-methylbut-2-enyl)xanthen-9-oneKi27200.0 [1]
7-[(2E)-3,7-Dimethylocta-2,6-dienoxy]-1,3-dihydroxyxanthen-9-oneIC5020600.0 [1]
7-[(2E)-3,7-Dimethylocta-2,6-dienoxy]-1,3-dihydroxyxanthen-9-oneKi17700.0 [1]
QuercetinIC507800.0 [1]
(-)-MitorubrinIC50200000.0 [1]
3-HydroxyterphenyllinIC5011300.0 [1]
[(7S,8S,8As)-7-hydroxy-7-methyl-6-oxo-3-[(E)-prop-1-enyl]-8,8a-dihydro-1H-isochromen-8-yl] 2,4-dihydroxy-6-methylbenzoateIC50200000.0 [1]
Aspernolide AIC5047330.0 [1]
Aspulvinone EIC50400000.0 [1]
Pinophilin BIC50200000.0 [1]
(4R)-Butyrolactone IIC5085130.0 [1]
3,3''-DihydroxyterphenyllinIC5014000.0 [1]
(+)-3''-Dimethylallyl-butyrolactone IIIC5014180.0 [1]
PrenylterphenyllinIC5025700.0 [1]
Methyl (2R)-4-hydroxy-3-(4-hydroxyphenyl)-2-[[(2R)-2-(2-hydroxypropan-2-yl)-2,3-dihydro-1-benzofuran-5-yl]methyl]-5-oxofuran-2-carboxylateIC50400000.0 [1]
MitorubrinolIC50200000.0 [1]
[(3E)-3-[(3,4-Dihydroxyphenyl)methylidene]-2-hydroxycyclohexen-1-yl]-phenylmethanoneIC5041000.0 [1]
(3R,4S,5R,6R)-5-(Hydroxymethyl)-6-pentylpiperidine-3,4-diolIC50100000.0 [1]
Flavipesolide BIC5010300.0 [1]
Flavipesolide CIC507630.0 [1]
[(7S,8S,8As)-7-hydroxy-3-[(E,3S)-3-hydroxybut-1-enyl]-7-methyl-6-oxo-8,8a-dihydro-1H-isochromen-8-yl] 2,4-dihydroxy-6-methylbenzoateIC5078600.0 [1]
[(7S,8S,8As)-7-hydroxy-7-methyl-6-oxo-3-[(E)-3-oxoprop-1-enyl]-8,8a-dihydro-1H-isochromen-8-yl] 2,4-dihydroxy-6-methylbenzoateIC5022900.0 [1]
4''-DeoxyterphenyllinIC50108200.0 [1]
(3R,4S,5R,6R)-5-(Hydroxymethyl)-6-methylpiperidine-3,4-diolIC50100000.0 [1]
(2E,6E)-2-Benzylidene-6-[(4-hydroxyphenyl)methylidene]cyclohexan-1-oneIC5042300.0 [1]
(3R,4S,5R,6R)-5-(Hydroxymethyl)-6-nonylpiperidine-3,4-diolIC50100000.0 [1]
2-[(2,2-Dimethyl-3,4-dihydrochromen-6-yl)methyl]-4-hydroxy-3-(4-hydroxyphenyl)-2H-furan-5-oneIC5011650.0 [1]
Methyl (7S,8S,8aS)-8-(2,4-dihydroxy-6-methylbenzoyl)oxy-7-hydroxy-7-methyl-6-oxo-8,8a-dihydro-1H-isochromene-3-carboxylateIC50200000.0 [1]
[(7S,8S,8As)-3-(dimethoxymethyl)-7-hydroxy-7-methyl-6-oxo-8,8a-dihydro-1H-isochromen-8-yl] 2,4-dihydroxy-6-methylbenzoateIC50200000.0 [1]
[(7S,8S)-7-Hydroxy-3-[(E)-3-hydroxyprop-1-enyl]-7-methyl-6-oxo-8H-isochromen-8-yl] 2,4-dihydroxy-6-methylbenzoateIC50200000.0 [1]
[(7S,8S,8As)-7-hydroxy-3-(3-methoxy-3-oxopropyl)-7-methyl-6-oxo-8,8a-dihydro-1H-isochromen-8-yl] 2,4-dihydroxy-6-methylbenzoateIC50200000.0 [1]
(1R,2S)-1-Methoxy-1-(2,4,5-trimethoxyphenyl)propan-2-olIC5080600.0 [1]
4-[2,5-Dimethoxy-3-propoxy-4-(4-propoxyphenyl)phenyl]phenolIC5010700.0 [1]
[2,5-Bis(4-hydroxyphenyl)-3,6-dimethoxyphenyl] furan-2-carboxylateIC5035400.0 [1]
4-Bromo-2,5-bis(4-hydroxyphenyl)-3,6-dimethoxyphenolIC507140.0 [1]
4-[3,6-Dimethoxy-2-prop-2-enoxy-4-(4-prop-2-enoxyphenyl)phenyl]phenolIC508770.0 [1]
4-[4-(4-Hydroxyphenyl)-2,5-dimethoxy-3-prop-2-enoxyphenyl]phenolIC5083800.0 [1]
5-[4-(2-Bromoethoxy)phenyl]-2-(4-hydroxyphenyl)-3,6-dimethoxyphenolIC5016100.0 [1]
3-(4-Hydroxyphenyl)-2,5-dimethoxy-6-(4-propoxyphenyl)phenolIC5012300.0 [1]
4-Chloro-2,5-bis(4-hydroxyphenyl)-3,6-dimethoxyphenolIC5031300.0 [1]
2-(4-Hydroxyphenyl)-3,6-dimethoxy-5-(4-phenylmethoxyphenyl)phenolIC5012500.0 [1]
4-[3,6-Dimethoxy-2-(3-methylbut-2-enoxy)-4-[4-(3-methylbut-2-enoxy)phenyl]phenyl]phenolIC5053100.0 [1]
4-[4-(4-Hydroxyphenyl)-2,5-dimethoxy-3-propoxyphenyl]phenolIC5019300.0 [1]
4-[3-(2-Bromoethoxy)-4-(4-hydroxyphenyl)-2,5-dimethoxyphenyl]phenolIC5018800.0 [1]
4-[3,6-Dimethoxy-2-prop-2-ynoxy-4-(4-prop-2-ynoxyphenyl)phenyl]phenolIC5020100.0 [1]
4-[3,6-Dimethoxy-2-propoxy-4-(4-propoxyphenyl)phenyl]phenolIC508690.0 [1]
2-(4-Hydroxyphenyl)-3,6-dimethoxy-5-(4-prop-2-enoxyphenyl)phenolIC5026500.0 [1]
2-(4-Hydroxyphenyl)-3,6-dimethoxy-5-(4-propoxyphenyl)phenolIC5010000.0 [1]
2-(4-Hydroxyphenyl)-3,6-dimethoxy-5-[4-[(4-phenylphenyl)methoxy]phenyl]phenolIC5012200.0 [1]
4-[2-(2-Bromoethoxy)-4-[4-(2-bromoethoxy)phenyl]-3,6-dimethoxyphenyl]phenolIC506670.0 [1]
2-(4-Hydroxyphenyl)-3,6-dimethoxy-5-[4-(3-methylbutoxy)phenyl]phenolIC5014300.0 [1]
3,6-Bis(4-hydroxyphenyl)-4-methoxybenzene-1,2-diolIC5013200.0 [1]
3-(4-Hydroxyphenyl)-2,5-dimethoxy-6-(4-phenylmethoxyphenyl)phenolIC5012500.0 [1]
(E)-3-[(7S,8S,8As)-8-(2,4-dihydroxy-6-methylbenzoyl)oxy-7-hydroxy-7-methyl-6-oxo-8,8a-dihydro-1H-isochromen-3-yl]prop-2-enoic acidIC50200000.0 [1]
4-[4-(4-Hydroxyphenyl)-2,5-dimethoxy-3-phenylmethoxyphenyl]phenolIC5019100.0 [1]
4-[4-(4-Hydroxyphenyl)-2,5-dimethoxy-3-(3-methylbut-2-enoxy)phenyl]phenolIC5023400.0 [1]
3-(4-Hydroxyphenyl)-2,5-dimethoxy-6-(4-prop-2-enoxyphenyl)phenolIC5032200.0 [1]
2-(4-Hydroxyphenyl)-3,6-dimethoxy-5-[4-(3-methylbut-2-enoxy)phenyl]phenolIC5020100.0 [1]
2-[4-(2-Bromoethoxy)phenyl]-5-(4-hydroxyphenyl)-3,6-dimethoxyphenolIC5018000.0 [1]
3-Hydroxy-2,5-bis(4-hydroxyphenyl)cyclohexa-2,5-diene-1,4-dioneIC5022700.0 [1]
3-(4-Hydroxyphenyl)-2,5-dimethoxy-6-[4-(3-methylbut-2-enoxy)phenyl]phenolIC5017500.0 [1]
(1Z,4E)-5-(3,4-Dihydroxyphenyl)-1-hydroxy-1-(2-hydroxyphenyl)penta-1,4-dien-3-oneIC5014300.0 [1]
2,6-Diethylpiperidine-3,4,5-triolIC5010000.0 [1]
4-Amino-1-[(3R,4S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-oneIC502500.0 [1]
(1Z,4E)-1-(2,4-Dihydroxyphenyl)-5-(2,5-dihydroxyphenyl)-1-hydroxypenta-1,4-dien-3-oneIC5020000.0 [1]
4-[(2,2-Dimethyl-3,4-dihydrochromen-6-yl)methyl]-2-hydroxy-3-(4-hydroxyphenyl)-2H-furan-5-oneIC5013360.0 [1]
(1Z,4E)-1,5-Bis(2,5-dihydroxyphenyl)-1-hydroxypenta-1,4-dien-3-oneIC5019600.0 [1]
Methyl (2R)-4-hydroxy-2-[[(3R)-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-6-yl]methyl]-3-(4-hydroxyphenyl)-5-oxofuran-2-carboxylateIC50110270.0 [1]
(2E,6E)-2-Benzylidene-6-[(3-hydroxyphenyl)methylidene]cyclohexan-1-oneIC5028400.0 [1]
(1Z,4E)-1-(2,5-Dihydroxyphenyl)-5-(furan-2-yl)-1-hydroxypenta-1,4-dien-3-oneIC5014100.0 [1]
(2E,6E)-2-Benzylidene-6-[(3,4-dihydroxyphenyl)methylidene]cyclohexan-1-oneIC5020300.0 [1]
(2S)-4-[[4-Hydroxy-3-(3-methylbut-2-enyl)phenyl]methyl]-3-(4-hydroxyphenyl)-2-methoxy-2H-furan-5-oneIC508650.0 [1]
(1Z,4E)-1-(5-Chloro-2-hydroxyphenyl)-1-hydroxy-5-(3-hydroxyphenyl)penta-1,4-dien-3-oneIC5036400.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Alpha glucosidase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/alpha-glucosidase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Alpha glucosidase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/alpha-glucosidase-inhibitors-ic50-ki.
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