| N-Tert-butyl-8-[[[(1S,2S)-2-(3-methyl-1,2,4-oxadiazol-5-yl)cyclopropanecarbonyl]amino]methyl]-5-[3-(trifluoromethoxy)phenyl]-3,4-dihydro-1H-isoquinoline-2-carboxamide | IC50 | 10000.0 [1] |
| (3S)-N-(2,4-Difluorophenyl)-3-ethyl-3-methyl-2,5-dioxo-1,4-dihydro-1,4-benzodiazepine-7-sulfonamide | IC50 | 6.31 [1], 12.59 [2] |
| N-(4-Methoxyphenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 55.0 [1], 4264.0 [2] |
| 5-(2-Ethyltetrazol-5-yl)-4-(4-methylphenyl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one | IC50 | 121.0 [1], 33330.0 [2] |
| 6-Methyl-4-(4-methylphenyl)-2-oxo-6-pentyl-1,3-dihydropyridine-3-carbonitrile | IC50 | 651.0 [1], 2049.0 [2] |
| (6R)-N-(4-Methoxyphenyl)-4-(4-methylphenyl)-2-oxo-6-[4-(4,4,4-trifluorobutoxy)phenyl]-6-(trifluoromethyl)piperidine-3-carboxamide | IC50 | 416.0 [1], 8430.0 [2] |
| 2-(4-Methoxyphenyl)-4-(4-methylphenyl)-6-oxo-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile | IC50 | 20.0 [1], 401.0 [2] |
| 4-(4-Methylphenyl)-2-[4-[2-[(2-methylpropan-2-yl)oxy]ethoxy]phenyl]-6-oxo-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile | IC50 | 126.0 [1], 656.0 [2] |
| 4-(4-Methylphenyl)-6-oxo-2-[4-(3-phenylpropoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile | IC50 | 13.0 [1], 5199.0 [2] |
| 2-[4-(2-Cyclopentylethoxy)phenyl]-4-(4-methylphenyl)-6-oxo-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile | IC50 | 57.0 [1], 396.0 [2] |
| 2-[4-(3-Methylbutoxy)phenyl]-4-(4-methylphenyl)-6-oxo-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile | IC50 | 15.0 [1], 263.0 [2] |
| 2-[4-(4-Methoxyphenyl)phenyl]-4-(4-methylphenyl)-6-oxo-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile | IC50 | 164.0 [1], 2546.0 [2] |
| N-(4-Fluorophenyl)-2-(4-methoxyphenyl)-4-(4-methylphenyl)-6-oxo-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 15.0 [1], 170.0 [2] |
| 4-(4-Methylphenyl)-6-oxo-2-(4-pentylphenyl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile | IC50 | 77.0 [1], 403.0 [2] |
| 4-(4-Methylphenyl)-6-oxo-2-(4-pyridin-2-ylphenyl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile | IC50 | 60.0 [1], 5387.0 [2] |
| N-(4-Fluorophenyl)-4-(4-methylphenyl)-6-oxo-2-(4-phenoxyphenyl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 8.0 [1], 60.0 [2] |
| N-(4-Fluorophenyl)-4-(4-methylphenyl)-6-oxo-2-(4-pyrimidin-4-yloxyphenyl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 64.0 [1], 127.0 [2] |
| N-(4-Fluorophenyl)-4-(4-methylphenyl)-6-oxo-2-(4-pyrazin-2-ylphenyl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 95.0 [1], 242.0 [2] |
| N-(4-Fluorophenyl)-4-(4-methylphenyl)-6-oxo-2-(4-pentylphenyl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 13.0 [1], 63.0 [2] |
| N-(4-Fluorophenyl)-4-(4-methylphenyl)-6-oxo-2-(4-pyrimidin-2-yloxyphenyl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 99.0 [1], 477.0 [2] |
| N-(4-Fluorophenyl)-4-(4-methylphenyl)-6-oxo-2-(4-phenylmethoxyphenyl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 20.0 [1], 258.0 [2] |
| 4-(4-Methylphenyl)-6-oxo-N-pentyl-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 20.0 [1], 846.0 [2] |
| 4-(4-Methylphenyl)-6-oxo-N-(2-phenylethyl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 16.0 [1], 412.0 [2] |
| N-(3-Methoxyphenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 29.0 [1], 275.0 [2] |
| 4-(4-Methylphenyl)-6-oxo-N-phenyl-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 4.0 [1], 53.0 [2] |
| N-(2-Chlorophenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 12.0 [1], 441.0 [2] |
| N-(4-Chlorophenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 24.0 [1], 156.0 [2] |
| 4-(3-Methoxyphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile | IC50 | 280.0 [1], 761.0 [2] |
| 4-(4-Methoxyphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile | IC50 | 27.0 [1], 89.0 [2] |
| 4-(4-Cyanophenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile | IC50 | 414.0 [1], 731.0 [2] |
| 4-(4-Fluorophenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile | IC50 | 697.0 [1], 2476.0 [2] |
| 4-(3-Chlorophenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile | IC50 | 1282.0 [1], 7523.0 [2] |
| 4-(3-Cyanophenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile | IC50 | 983.0 [1], 9230.0 [2] |
| 6-Oxo-4-phenyl-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile | IC50 | 1917.0 [1], 2931.0 [2] |
| 4-(4-Chlorophenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile | IC50 | 214.0 [1], 3519.0 [2] |
| 4-Naphthalen-2-yl-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile | IC50 | 25.0 [1], 397.0 [2] |
| 6-Oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-dihydropyridine-5-carbonitrile | IC50 | 209.0 [1], 873.0 [2] |
| 6-Oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-4-[4-(trifluoromethoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile | IC50 | 45.0 [1], 1856.0 [2] |
| 4-(4-Ethoxyphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile | IC50 | 25.0 [1], 130.0 [2] |
| 4-(2-Fluoro-4-methoxyphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile | IC50 | 2.0 [1], 916.0 [2] |
| N,4-Bis(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 2.0 [1], 133.0 [2] |
| N-(3-Fluoro-4-methoxyphenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 2.0 [1], 115.0 [2] |
| N-(3-Fluoro-4-methylphenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 7.0 [1], 1465.0 [2] |
| N-(4-Methoxyphenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(2,2,2-trifluoroethoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 5.0 [1], 28.0 [2] |
| 4-(4-Methylphenyl)-6-oxo-2-[4-(2,2,2-trifluoroethoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile | IC50 | 20.0 [1], 731.0 [2] |
| 4-(4-Methylphenyl)-5-(2H-tetrazol-5-yl)-2-[4-(2,2,2-trifluoroethoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one | IC50 | 78.0 [1], 815.0 [2] |
| 4-[4-(Difluoromethoxy)phenyl]-5-(2H-tetrazol-5-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one | IC50 | 37.0 [1], 46.0 [2] |
| 4-(4-Methylphenyl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-5-[4-(trifluoromethoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one | IC50 | 4.0 [1], 32.0 [2] |
| 4-(2-Fluoro-4-methoxyphenyl)-5-(2H-tetrazol-5-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one | IC50 | 43.0 [1], 95.0 [2] |
| 5-(2H-Tetrazol-5-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-dihydropyridin-6-one | IC50 | 69.0 [1], 154.0 [2] |
| 4-(4-Chlorophenyl)-5-(2H-tetrazol-5-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one | IC50 | 108.0 [1], 379.0 [2] |
| 4-(4-Methylphenyl)-6-oxo-N-[6-(2H-tetrazol-5-yl)pyridin-3-yl]-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 7.0 [1], 9.0 [2] |
| 2-(4-Bromophenyl)-4-(4-methylphenyl)-5-(2H-tetrazol-5-yl)-2-(trifluoromethyl)-1,3-dihydropyridin-6-one | IC50 | 639.0 [1], 1297.0 [2] |
| 4-(4-Methylphenyl)-5-(5H-tetrazol-5-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one | IC50 | 8.0 [1], 158.0 [2] |
| 4-(4-Methylphenyl)-2-[4-(4,4,5,5,5-pentafluoropentoxy)phenyl]-5-(2H-tetrazol-5-yl)-2-(trifluoromethyl)-1,3-dihydropyridin-6-one | IC50 | 4.0 [1], 32.0 [2] |
| N-Cyclobutyl-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 6.0 [1], 58.0 [2] |
| N-Cyclohexyl-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 20.0 [1], 231.0 [2] |
| N-Methyl-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 5.0 [1], 743.0 [2] |
| 2-[4-(Cyclopenten-1-yl)phenyl]-4-(4-methylphenyl)-6-oxo-N-(2H-tetrazol-5-yl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 33.0 [1], 1874.0 [2] |
| 2-[3-(Cyclohexen-1-yl)phenyl]-4-(4-methylphenyl)-6-oxo-N-(2H-tetrazol-5-yl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 10.0 [1], 655.0 [2] |
| 4-(4-Methylphenyl)-N-(1,2-oxazol-5-yl)-6-oxo-2-(trifluoromethyl)-2-[4-(3,3,3-trifluoropropoxy)phenyl]-1,3-dihydropyridine-5-carboxamide | IC50 | 1.0 [1], 20.0 [2] |
| 5,5-Difluoro-N-(4-methoxyphenyl)-4-(4-methylphenyl)-2-oxo-6-(trifluoromethyl)-6-[4-(3,3,3-trifluoropropoxy)phenyl]-1H-pyridine-3-carboxamide | IC50 | 127.0 [1], 1518.0 [2] |
| 4-(2-Fluoro-4-methoxyphenyl)-5-(tetrazol-1-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one | IC50 | 10.0 [1], 93.0 [2] |
| 4-(4-Methoxyphenyl)-5-(tetrazol-1-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one | IC50 | 4.0 [1], 156.0 [2] |
| 4-(2,4-Dimethylphenyl)-N-(4-methoxyphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 9.0 [1], 102.0 [2] |
| N-[5,5-Difluoro-4-(4-methylphenyl)-2-oxo-6-[4-(4,4,4-trifluorobutoxy)phenyl]-6-(trifluoromethyl)-1H-pyridin-3-yl]-3-methyl-1,2-oxazole-5-carboxamide | IC50 | 3.0 [1], 11.0 [2] |
| 4-Methyl-N-[4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]-1,2-oxazole-5-carboxamide | IC50 | 84.0 [1], 168.0 [2] |
| 6-Chloro-N-[4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]pyridazine-3-carboxamide | IC50 | 75.0 [1], 302.0 [2] |
| N-[5,5-Difluoro-4-(4-methylphenyl)-2-oxo-6-[4-(4,4,4-trifluorobutoxy)phenyl]-6-(trifluoromethyl)-1H-pyridin-3-yl]-4-methoxybenzamide | IC50 | 47.0 [1], 1176.0 [2] |
| N-[4-[4-(Difluoromethoxy)phenyl]-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]-1,2-oxazole-5-carboxamide | IC50 | 2.0 [1], 8.0 [2] |
| 2-Chloro-5-fluoro-N-[4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]benzamide | IC50 | 57.0 [1], 724.0 [2] |
| N-[2-(4-Butoxyphenyl)-4-(4-methoxyphenyl)-6-oxo-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]-1,2-oxazole-5-carboxamide | IC50 | 3.0 [1], 16.0 [2] |
| 2-N-Hexadecyl-5-N-(4-methoxyphenyl)-2-methyl-4-(4-methylphenyl)-6-oxo-1,3-dihydropyridine-2,5-dicarboxamide | IC50 | 43.0 [1], 63.0 [2] |
| 5-N-(4-Methoxyphenyl)-2-methyl-4-(4-methylphenyl)-2-N-octyl-6-oxo-1,3-dihydropyridine-2,5-dicarboxamide | IC50 | 60.0 [1], 237.0 [2] |
| 5-N-(4-Methoxyphenyl)-2-methyl-4-(4-methylphenyl)-6-oxo-2-N-(4-phenylbutyl)-1,3-dihydropyridine-2,5-dicarboxamide | IC50 | 47.0 [1], 78.0 [2] |
| 3-Bromo-N-[4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]-1,2-oxazole-5-carboxamide | IC50 | 2.0 [1], 24.0 [2] |
| N-[4-(4-Methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]-3-phenylmethoxy-1,2-oxazole-5-carboxamide | IC50 | 30.0 [1], 36.0 [2] |
| N-(5-Methoxypyrazin-2-yl)-4-(4-methylphenyl)-6-oxo-2-(trifluoromethyl)-2-[4-(5,5,5-trifluoropentoxy)phenyl]-1,3-dihydropyridine-5-carboxamide | IC50 | 10.0 [1], 21.0 [2] |
| (2S)-N-(4-Methoxyphenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 2.0 [1], 14.0 [2] |
| 2-N-Heptyl-5-N-(4-methoxyphenyl)-2-methyl-4-(4-methylphenyl)-6-oxo-1,3-dihydropyridine-2,5-dicarboxamide | IC50 | 102.0 [1], 237.0 [2] |
| N-(6-Methoxypyridin-3-yl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 5.0 [1], 11.0 [2] |
| N-Cyclopropyl-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 21.0 [1], 94.0 [2] |
| 4-(4-Methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-N-[4-(trifluoromethoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 1.0 [1], 89.0 [2] |
| N-(4-Hydroxyphenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamide | IC50 | 1.0 [1], 14.0 [2] |
| 4-[4-(Difluoromethoxy)phenyl]-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile | IC50 | 16.0 [1], 175.0 [2] |
| 4-(4-Methylphenyl)-5-(2H-tetrazol-5-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one | IC50 | 8.0 [1], 35.0 [2] |
| 4-(4-Methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile | IC50 | 171.0 [1], 5073.0 [2] |
| 4-(4-Methylphenyl)-6-oxo-2-(trifluoromethyl)-2-[4-(3,3,3-trifluoropropoxy)phenyl]-1,3-dihydropyridine-5-carbonitrile | IC50 | 14.0 [1], 91.0 [2] |
| 4-[4-(Difluoromethoxy)phenyl]-5-(tetrazol-1-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one | IC50 | 6.0 [1], 53.0 [2] |
| 5-Methyl-N-[4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]-1,3,4-oxadiazole-2-carboxamide | IC50 | 8.0 [1], 34.0 [2] |
| 2-Methyl-N-[(2S)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]benzamide | IC50 | 24.0 [1], 672.0 [2] |
| (2R)-4-(4-Methylphenyl)-5-(2H-tetrazol-5-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one | IC50 | 261.0 [1], 1400.0 [2] |
| 2-(4-Butoxyphenyl)-4-(4-methylphenyl)-6-oxo-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrile | IC50 | 21.0 [1], 309.0 [2] |
| 4-(4-Methylphenyl)-5-nitro-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one | IC50 | 35.0 [1], 3333.0 [2] |
| 4-(4-Methylphenyl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-5-[5-(trifluoromethyl)-1,3,4-oxadiazol-2-yl]-1,3-dihydropyridin-6-one | IC50 | 138.0 [1], 2716.0 [2] |
| 4-(4-Methylphenyl)-5-(2H-tetrazol-5-yl)-2-[4-(6,6,6-trifluorohexoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-one | IC50 | 48.0 [1], 407.0 [2] |
| 2-Methyl-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-N-[4-(trifluoromethoxy)phenyl]-1,3-dihydropyridine-5-carboxamide | IC50 | 13.0 [1], 48.0 [2] |
| (6S)-N-(4-Methoxyphenyl)-4-(4-methylphenyl)-2-oxo-6-[4-(4,4,4-trifluorobutoxy)phenyl]-6-(trifluoromethyl)piperidine-3-carboxamide | IC50 | 25.0 [1], 416.0 [2] |
| (6S)-3-Fluoro-4-(4-methoxyphenyl)-2-oxo-6-[4-(4,4,4-trifluorobutoxy)phenyl]-6-(trifluoromethyl)-1H-pyridine-3-carbonitrile | IC50 | 2049.0 [1], 33330.0 [2] |
| (6R)-3-Fluoro-4-(4-methoxyphenyl)-2-oxo-6-[4-(4,4,4-trifluorobutoxy)phenyl]-6-(trifluoromethyl)-1H-pyridine-3-carbonitrile | IC50 | 2049.0 [1], 33330.0 [2] |