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Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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N-Tert-butyl-8-[[[(1S,2S)-2-(3-methyl-1,2,4-oxadiazol-5-yl)cyclopropanecarbonyl]amino]methyl]-5-[3-(trifluoromethoxy)phenyl]-3,4-dihydro-1H-isoquinoline-2-carboxamideIC5010000.0 [1]
(3S)-N-(2,4-Difluorophenyl)-3-ethyl-3-methyl-2,5-dioxo-1,4-dihydro-1,4-benzodiazepine-7-sulfonamideIC506.31 [1], 12.59 [2]
N-(4-Methoxyphenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC5055.0 [1], 4264.0 [2]
5-(2-Ethyltetrazol-5-yl)-4-(4-methylphenyl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-oneIC50121.0 [1], 33330.0 [2]
6-Methyl-4-(4-methylphenyl)-2-oxo-6-pentyl-1,3-dihydropyridine-3-carbonitrileIC50651.0 [1], 2049.0 [2]
(6R)-N-(4-Methoxyphenyl)-4-(4-methylphenyl)-2-oxo-6-[4-(4,4,4-trifluorobutoxy)phenyl]-6-(trifluoromethyl)piperidine-3-carboxamideIC50416.0 [1], 8430.0 [2]
2-(4-Methoxyphenyl)-4-(4-methylphenyl)-6-oxo-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrileIC5020.0 [1], 401.0 [2]
4-(4-Methylphenyl)-2-[4-[2-[(2-methylpropan-2-yl)oxy]ethoxy]phenyl]-6-oxo-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrileIC50126.0 [1], 656.0 [2]
4-(4-Methylphenyl)-6-oxo-2-[4-(3-phenylpropoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrileIC5013.0 [1], 5199.0 [2]
2-[4-(2-Cyclopentylethoxy)phenyl]-4-(4-methylphenyl)-6-oxo-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrileIC5057.0 [1], 396.0 [2]
2-[4-(3-Methylbutoxy)phenyl]-4-(4-methylphenyl)-6-oxo-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrileIC5015.0 [1], 263.0 [2]
2-[4-(4-Methoxyphenyl)phenyl]-4-(4-methylphenyl)-6-oxo-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrileIC50164.0 [1], 2546.0 [2]
N-(4-Fluorophenyl)-2-(4-methoxyphenyl)-4-(4-methylphenyl)-6-oxo-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC5015.0 [1], 170.0 [2]
4-(4-Methylphenyl)-6-oxo-2-(4-pentylphenyl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrileIC5077.0 [1], 403.0 [2]
4-(4-Methylphenyl)-6-oxo-2-(4-pyridin-2-ylphenyl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrileIC5060.0 [1], 5387.0 [2]
N-(4-Fluorophenyl)-4-(4-methylphenyl)-6-oxo-2-(4-phenoxyphenyl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC508.0 [1], 60.0 [2]
N-(4-Fluorophenyl)-4-(4-methylphenyl)-6-oxo-2-(4-pyrimidin-4-yloxyphenyl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC5064.0 [1], 127.0 [2]
N-(4-Fluorophenyl)-4-(4-methylphenyl)-6-oxo-2-(4-pyrazin-2-ylphenyl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC5095.0 [1], 242.0 [2]
N-(4-Fluorophenyl)-4-(4-methylphenyl)-6-oxo-2-(4-pentylphenyl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC5013.0 [1], 63.0 [2]
N-(4-Fluorophenyl)-4-(4-methylphenyl)-6-oxo-2-(4-pyrimidin-2-yloxyphenyl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC5099.0 [1], 477.0 [2]
N-(4-Fluorophenyl)-4-(4-methylphenyl)-6-oxo-2-(4-phenylmethoxyphenyl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC5020.0 [1], 258.0 [2]
4-(4-Methylphenyl)-6-oxo-N-pentyl-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC5020.0 [1], 846.0 [2]
4-(4-Methylphenyl)-6-oxo-N-(2-phenylethyl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC5016.0 [1], 412.0 [2]
N-(3-Methoxyphenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC5029.0 [1], 275.0 [2]
4-(4-Methylphenyl)-6-oxo-N-phenyl-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC504.0 [1], 53.0 [2]
N-(2-Chlorophenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC5012.0 [1], 441.0 [2]
N-(4-Chlorophenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC5024.0 [1], 156.0 [2]
4-(3-Methoxyphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrileIC50280.0 [1], 761.0 [2]
4-(4-Methoxyphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrileIC5027.0 [1], 89.0 [2]
4-(4-Cyanophenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrileIC50414.0 [1], 731.0 [2]
4-(4-Fluorophenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrileIC50697.0 [1], 2476.0 [2]
4-(3-Chlorophenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrileIC501282.0 [1], 7523.0 [2]
4-(3-Cyanophenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrileIC50983.0 [1], 9230.0 [2]
6-Oxo-4-phenyl-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrileIC501917.0 [1], 2931.0 [2]
4-(4-Chlorophenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrileIC50214.0 [1], 3519.0 [2]
4-Naphthalen-2-yl-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrileIC5025.0 [1], 397.0 [2]
6-Oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-dihydropyridine-5-carbonitrileIC50209.0 [1], 873.0 [2]
6-Oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-4-[4-(trifluoromethoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrileIC5045.0 [1], 1856.0 [2]
4-(4-Ethoxyphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrileIC5025.0 [1], 130.0 [2]
4-(2-Fluoro-4-methoxyphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrileIC502.0 [1], 916.0 [2]
N,4-Bis(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC502.0 [1], 133.0 [2]
N-(3-Fluoro-4-methoxyphenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC502.0 [1], 115.0 [2]
N-(3-Fluoro-4-methylphenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC507.0 [1], 1465.0 [2]
N-(4-Methoxyphenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(2,2,2-trifluoroethoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC505.0 [1], 28.0 [2]
4-(4-Methylphenyl)-6-oxo-2-[4-(2,2,2-trifluoroethoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrileIC5020.0 [1], 731.0 [2]
4-(4-Methylphenyl)-5-(2H-tetrazol-5-yl)-2-[4-(2,2,2-trifluoroethoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-oneIC5078.0 [1], 815.0 [2]
4-[4-(Difluoromethoxy)phenyl]-5-(2H-tetrazol-5-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-oneIC5037.0 [1], 46.0 [2]
4-(4-Methylphenyl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-5-[4-(trifluoromethoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-oneIC504.0 [1], 32.0 [2]
4-(2-Fluoro-4-methoxyphenyl)-5-(2H-tetrazol-5-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-oneIC5043.0 [1], 95.0 [2]
5-(2H-Tetrazol-5-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-4-[4-(trifluoromethyl)phenyl]-1,3-dihydropyridin-6-oneIC5069.0 [1], 154.0 [2]
4-(4-Chlorophenyl)-5-(2H-tetrazol-5-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-oneIC50108.0 [1], 379.0 [2]
4-(4-Methylphenyl)-6-oxo-N-[6-(2H-tetrazol-5-yl)pyridin-3-yl]-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC507.0 [1], 9.0 [2]
2-(4-Bromophenyl)-4-(4-methylphenyl)-5-(2H-tetrazol-5-yl)-2-(trifluoromethyl)-1,3-dihydropyridin-6-oneIC50639.0 [1], 1297.0 [2]
4-(4-Methylphenyl)-5-(5H-tetrazol-5-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-oneIC508.0 [1], 158.0 [2]
4-(4-Methylphenyl)-2-[4-(4,4,5,5,5-pentafluoropentoxy)phenyl]-5-(2H-tetrazol-5-yl)-2-(trifluoromethyl)-1,3-dihydropyridin-6-oneIC504.0 [1], 32.0 [2]
N-Cyclobutyl-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC506.0 [1], 58.0 [2]
N-Cyclohexyl-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC5020.0 [1], 231.0 [2]
N-Methyl-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC505.0 [1], 743.0 [2]
2-[4-(Cyclopenten-1-yl)phenyl]-4-(4-methylphenyl)-6-oxo-N-(2H-tetrazol-5-yl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC5033.0 [1], 1874.0 [2]
2-[3-(Cyclohexen-1-yl)phenyl]-4-(4-methylphenyl)-6-oxo-N-(2H-tetrazol-5-yl)-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC5010.0 [1], 655.0 [2]
4-(4-Methylphenyl)-N-(1,2-oxazol-5-yl)-6-oxo-2-(trifluoromethyl)-2-[4-(3,3,3-trifluoropropoxy)phenyl]-1,3-dihydropyridine-5-carboxamideIC501.0 [1], 20.0 [2]
5,5-Difluoro-N-(4-methoxyphenyl)-4-(4-methylphenyl)-2-oxo-6-(trifluoromethyl)-6-[4-(3,3,3-trifluoropropoxy)phenyl]-1H-pyridine-3-carboxamideIC50127.0 [1], 1518.0 [2]
4-(2-Fluoro-4-methoxyphenyl)-5-(tetrazol-1-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-oneIC5010.0 [1], 93.0 [2]
4-(4-Methoxyphenyl)-5-(tetrazol-1-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-oneIC504.0 [1], 156.0 [2]
4-(2,4-Dimethylphenyl)-N-(4-methoxyphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC509.0 [1], 102.0 [2]
N-[5,5-Difluoro-4-(4-methylphenyl)-2-oxo-6-[4-(4,4,4-trifluorobutoxy)phenyl]-6-(trifluoromethyl)-1H-pyridin-3-yl]-3-methyl-1,2-oxazole-5-carboxamideIC503.0 [1], 11.0 [2]
4-Methyl-N-[4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]-1,2-oxazole-5-carboxamideIC5084.0 [1], 168.0 [2]
6-Chloro-N-[4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]pyridazine-3-carboxamideIC5075.0 [1], 302.0 [2]
N-[5,5-Difluoro-4-(4-methylphenyl)-2-oxo-6-[4-(4,4,4-trifluorobutoxy)phenyl]-6-(trifluoromethyl)-1H-pyridin-3-yl]-4-methoxybenzamideIC5047.0 [1], 1176.0 [2]
N-[4-[4-(Difluoromethoxy)phenyl]-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]-1,2-oxazole-5-carboxamideIC502.0 [1], 8.0 [2]
2-Chloro-5-fluoro-N-[4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]benzamideIC5057.0 [1], 724.0 [2]
N-[2-(4-Butoxyphenyl)-4-(4-methoxyphenyl)-6-oxo-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]-1,2-oxazole-5-carboxamideIC503.0 [1], 16.0 [2]
2-N-Hexadecyl-5-N-(4-methoxyphenyl)-2-methyl-4-(4-methylphenyl)-6-oxo-1,3-dihydropyridine-2,5-dicarboxamideIC5043.0 [1], 63.0 [2]
5-N-(4-Methoxyphenyl)-2-methyl-4-(4-methylphenyl)-2-N-octyl-6-oxo-1,3-dihydropyridine-2,5-dicarboxamideIC5060.0 [1], 237.0 [2]
5-N-(4-Methoxyphenyl)-2-methyl-4-(4-methylphenyl)-6-oxo-2-N-(4-phenylbutyl)-1,3-dihydropyridine-2,5-dicarboxamideIC5047.0 [1], 78.0 [2]
3-Bromo-N-[4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]-1,2-oxazole-5-carboxamideIC502.0 [1], 24.0 [2]
N-[4-(4-Methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]-3-phenylmethoxy-1,2-oxazole-5-carboxamideIC5030.0 [1], 36.0 [2]
N-(5-Methoxypyrazin-2-yl)-4-(4-methylphenyl)-6-oxo-2-(trifluoromethyl)-2-[4-(5,5,5-trifluoropentoxy)phenyl]-1,3-dihydropyridine-5-carboxamideIC5010.0 [1], 21.0 [2]
(2S)-N-(4-Methoxyphenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC502.0 [1], 14.0 [2]
2-N-Heptyl-5-N-(4-methoxyphenyl)-2-methyl-4-(4-methylphenyl)-6-oxo-1,3-dihydropyridine-2,5-dicarboxamideIC50102.0 [1], 237.0 [2]
N-(6-Methoxypyridin-3-yl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC505.0 [1], 11.0 [2]
N-Cyclopropyl-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC5021.0 [1], 94.0 [2]
4-(4-Methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-N-[4-(trifluoromethoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC501.0 [1], 89.0 [2]
N-(4-Hydroxyphenyl)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carboxamideIC501.0 [1], 14.0 [2]
4-[4-(Difluoromethoxy)phenyl]-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrileIC5016.0 [1], 175.0 [2]
4-(4-Methylphenyl)-5-(2H-tetrazol-5-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-oneIC508.0 [1], 35.0 [2]
4-(4-Methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrileIC50171.0 [1], 5073.0 [2]
4-(4-Methylphenyl)-6-oxo-2-(trifluoromethyl)-2-[4-(3,3,3-trifluoropropoxy)phenyl]-1,3-dihydropyridine-5-carbonitrileIC5014.0 [1], 91.0 [2]
4-[4-(Difluoromethoxy)phenyl]-5-(tetrazol-1-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-oneIC506.0 [1], 53.0 [2]
5-Methyl-N-[4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]-1,3,4-oxadiazole-2-carboxamideIC508.0 [1], 34.0 [2]
2-Methyl-N-[(2S)-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-5-yl]benzamideIC5024.0 [1], 672.0 [2]
(2R)-4-(4-Methylphenyl)-5-(2H-tetrazol-5-yl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-oneIC50261.0 [1], 1400.0 [2]
2-(4-Butoxyphenyl)-4-(4-methylphenyl)-6-oxo-2-(trifluoromethyl)-1,3-dihydropyridine-5-carbonitrileIC5021.0 [1], 309.0 [2]
4-(4-Methylphenyl)-5-nitro-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-oneIC5035.0 [1], 3333.0 [2]
4-(4-Methylphenyl)-2-[4-(4,4,4-trifluorobutoxy)phenyl]-2-(trifluoromethyl)-5-[5-(trifluoromethyl)-1,3,4-oxadiazol-2-yl]-1,3-dihydropyridin-6-oneIC50138.0 [1], 2716.0 [2]
4-(4-Methylphenyl)-5-(2H-tetrazol-5-yl)-2-[4-(6,6,6-trifluorohexoxy)phenyl]-2-(trifluoromethyl)-1,3-dihydropyridin-6-oneIC5048.0 [1], 407.0 [2]
2-Methyl-4-(4-methylphenyl)-6-oxo-2-[4-(4,4,4-trifluorobutoxy)phenyl]-N-[4-(trifluoromethoxy)phenyl]-1,3-dihydropyridine-5-carboxamideIC5013.0 [1], 48.0 [2]
(6S)-N-(4-Methoxyphenyl)-4-(4-methylphenyl)-2-oxo-6-[4-(4,4,4-trifluorobutoxy)phenyl]-6-(trifluoromethyl)piperidine-3-carboxamideIC5025.0 [1], 416.0 [2]
(6S)-3-Fluoro-4-(4-methoxyphenyl)-2-oxo-6-[4-(4,4,4-trifluorobutoxy)phenyl]-6-(trifluoromethyl)-1H-pyridine-3-carbonitrileIC502049.0 [1], 33330.0 [2]
(6R)-3-Fluoro-4-(4-methoxyphenyl)-2-oxo-6-[4-(4,4,4-trifluorobutoxy)phenyl]-6-(trifluoromethyl)-1H-pyridine-3-carbonitrileIC502049.0 [1], 33330.0 [2]
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References

This online tool may be cited as follows

MLA

"Quest Database™ Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/alpha-1-6-mannosyl-glycoprotein-2-beta-n-acetylglucosaminyltransferase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/alpha-1-6-mannosyl-glycoprotein-2-beta-n-acetylglucosaminyltransferase-inhibitors-ic50-ki.
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