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Alkaline phosphatase, tissue-nonspecific isozyme Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamideIC50230.0 [1]
2,5-Dimethoxy-N-(3-quinolinyl)benzenesulfonamideKi340.0 [1], 590.0 [2]
LevamisoleIC505000.0 [1], 19200.0 [2], 20200.0 [3], 20210.0 [4]
LevamisoleKi16000.0 [1]
PhenylalanineIC505000.0 [1], 100100.0 [2], 200000.0 [3]
TheophyllineIC505000.0 [1], 100000.0 [2]
TheophyllineKi82000.0 [1]
5-Bromo-2-methoxy-N-(quinolin-3-yl)benzenesulfonamideIC506.0 [1], 120.0 [2], 20000.0 [3]
Levamisole hydrochlorideKi16000.0 [1], 93000.0 [2]
3-Pyridinecarboxamide, 5-[[(5-chloro-2-methoxyphenyl)sulfonyl]amino]-IC5016.0 [1], 105.0 [2]
5-[(5-Chloro-2-methoxyphenyl)sulfonylamino]pyridine-3-carboxylic acidIC50134.0 [1], 20000.0 [2]
[(5-Chloro-2-methoxyphenyl)sulfonyl]-3-pyridylamineIC5084.0 [1], 795.0 [2]
5-Chloro-2-methoxy-N-quinolin-3-ylbenzenesulfonamideIC506.0 [1], 4510.0 [2]
[(2-Methoxy-4-methylphenyl)sulfonyl]-3-pyridylamineIC50896.0 [1], 3550.0 [2]
5-[[5-Chloro-2-(trifluoromethoxy)phenyl]sulfonylamino]pyridine-3-carboxamideIC50432.0 [1], 18700.0 [2]
2-Methoxy-5-phenyl-N-pyridin-3-ylbenzenesulfonamideIC50876.0 [1], 20000.0 [2]
5-Bromo-2-methoxy-N-pyridin-3-ylbenzenesulfonamideIC5043.0 [1], 543.0 [2]
5-Chloro-2-methoxy-N-(5-pyridin-4-ylpyridin-3-yl)benzenesulfonamideIC5073.0 [1], 20000.0 [2]
Methyl 5-[(5-chloro-2-methoxyphenyl)sulfonylamino]pyridine-3-carboxylateIC5065.0 [1], 20000.0 [2]
2-Methoxy-N-quinolin-3-yl-5-(trifluoromethyl)benzenesulfonamideIC5026.0 [1], 20000.0 [2]
3-Pyridinecarboxamide, 5-[[(5-fluoro-2-methoxyphenyl)sulfonyl]amino]-IC5019.0 [1], 109.0 [2]
3-Pyridinecarboxamide, 5-[[(5-bromo-2-methoxyphenyl)sulfonyl]amino]-IC5014.0 [1], 121.0 [2]
5-[(5-Chloro-2-methoxyphenyl)sulfonylamino]-N-methylpyridine-3-carboxamideIC50109.0 [1], 20000.0 [2]
5-[(5-Chloro-2-methoxyphenyl)sulfonylamino]-N-ethylpyridine-3-carboxamideIC50193.0 [1], 20000.0 [2]
5-Chloro-2-methoxy-N-[5-(4-methoxyphenyl)pyridin-3-yl]benzenesulfonamideIC5023.0 [1], 16000.0 [2]
5-[[2-Methoxy-5-(trifluoromethoxy)phenyl]sulfonylamino]pyridine-3-carboxamideIC50131.0 [1], 1560.0 [2]
2-Methoxy-N-pyridin-3-yl-5-(trifluoromethyl)benzenesulfonamideIC50183.0 [1], 3010.0 [2]
2,5-Dimethoxy-N-(5-pyridin-4-ylpyridin-3-yl)benzenesulfonamideIC5073.0 [1], 20000.0 [2]
TryptophanIC505000.0 [1]
LeucineIC505000.0 [1]
L-HomoarginineIC505000.0 [1]
(S)-2-Amino-4-methylpentanamideIC505000.0 [1]
1-(3,4-Dihydroxyphenyl)-2-{[1-(4-methoxyphenyl)-1H-tetrazol-5-yl]thio}ethanoneIC508000.0 [1]
2-{[2-(3,4-Dihydroxyphenyl)-2-oxoethyl]thio}-4-(methoxymethyl)-6-methylnicotinonitrileIC504800.0 [1]
1-(3,4-Dihydroxyphenyl)-2-(1-imidazolyl)ethanoneIC50100000.0 [1]
Methyl 5-(2,4-dichlorophenyl)pyrazole-3-carboxylateIC50500.0 [1]
1-(3,4-Dihydroxyphenyl)-2-[(4,6-dimethyl-2-pyrimidinyl)thio]ethanoneIC508600.0 [1]
1,4-Dihydrochromeno[4,3-c]pyrazole-3-carboxylic acidIC501300.0 [1]
CID 24790972IC50100000.0 [1]
N-Benzyl-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamideIC50100000.0 [1]
CID 24790974IC50100000.0 [1]
CID 24790980IC50100000.0 [1]
CID 24790981IC50100000.0 [1]
N-(3,4-Dimethylphenyl)-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamideIC50100000.0 [1]
N-[(4-Fluorophenyl)methyl]-3-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]propanamideIC50100000.0 [1]
3-[2-(3,4-Dihydroxyphenyl)-2-oxoethyl]-6,7-dimethoxy-2-benzofuran-1(3H)-oneIC5029200.0 [1]
1H-Pyrazole, 3,5-dimethyl-1-(4-pyridinylcarbonyl)-IC506510.0 [1]
2-Methoxy-5-methyl-N-pyridin-3-yl-benzenesulfonamideIC501850.0 [1]
5-(2-Chlorophenyl)-1H-pyrazole-3-carboxylic acidIC50980.0 [1]
1-(4-Chlorobenzoyl)-3,5-dimethyl-1H-pyrazoleIC505710.0 [1]
2,5-Dimethoxy-N-3-pyridinylbenzenesulfonamideIC501060.0 [1]
N-(2,5-Dimethylphenyl)-2-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonylamino]acetamideIC5035000.0 [1]
2-Ethoxy-5-methyl-N-pyridin-3-ylbenzenesulfonamideIC501130.0 [1]
4-Methyl-7,8-bis[(methylsulfonyl)oxy]-2H-1-benzopyran-2-oneIC502160.0 [1]
4-Bromo-2,5-dimethoxy-N-(pyridin-3-yl)benzenesulfonamideIC501550.0 [1]
(4-Chloro-3,5-dimethyl-1H-pyrazol-1-yl)(4-chlorophenyl)methanoneIC50910.0 [1]
4-Chloro-3,5-dimethylpyrazolyl 4-pyridyl ketoneIC5042000.0 [1]
Methanone, (4-aminophenyl)(3,5-dimethyl-1H-pyrazol-1-yl)-IC503580.0 [1]
(E)-1-(4-Chloro-3,5-dimethylpyrazol-1-yl)-3-phenylprop-2-en-1-oneIC5013300.0 [1]
(3-Chloro-4-methyl-2-oxochromen-7-yl) 4-chloro-3-nitrobenzenesulfonateIC501420.0 [1]
(3-Chloro-4-methyl-2-oxochromen-7-yl) ethanesulfonateIC509370.0 [1]
(3-Cyano-4-methyl-2-oxochromen-7-yl) 4-nitrobenzenesulfonateIC501330.0 [1]
(3-Cyano-4-methyl-2-oxochromen-7-yl) butane-1-sulfonateIC50850.0 [1]
(3-Cyano-4-methyl-2-oxochromen-7-yl) 4-chlorobenzenesulfonateIC502520.0 [1]
(3-Chloro-4-methyl-2-oxochromen-7-yl) 4-propylbenzenesulfonateIC5017600.0 [1]
(3-Chloro-4-methyl-2-oxochromen-7-yl) methanesulfonateIC502510.0 [1]
[8-(4-Methoxyphenyl)sulfonyloxy-4-methyl-2-oxochromen-7-yl] 4-methoxybenzenesulfonateIC502590.0 [1]
(4-Methyl-8-nitro-2-oxochromen-7-yl) 4-chloro-3-nitrobenzenesulfonateIC507710.0 [1]
(3-Cyano-4-methyl-2-oxochromen-7-yl) 3-nitrobenzenesulfonateIC502420.0 [1]
[8-(2,5-Dichlorophenyl)sulfonyloxy-4-methyl-2-oxochromen-7-yl] 2,5-dichlorobenzenesulfonateIC501330.0 [1]
(3-Cyano-4-methyl-2-oxochromen-7-yl) benzenesulfonateIC503530.0 [1]
(3-Cyano-4-methyl-2-oxochromen-7-yl) octane-1-sulfonateIC50920.0 [1]
(3-Chloro-4-methyl-2-oxochromen-7-yl) butane-1-sulfonateIC501640.0 [1]
(3-Cyano-4-methyl-2-oxochromen-7-yl) 4-propylbenzenesulfonateIC509230.0 [1]
(3-Cyano-4-methyl-2-oxochromen-7-yl) 2,5-dichlorobenzenesulfonateIC502470.0 [1]
(4-Methyl-8-nitro-2-oxochromen-7-yl) 4-octylbenzenesulfonateIC502540.0 [1]
[4-Methyl-8-(4-nitrophenyl)sulfonyloxy-2-oxochromen-7-yl] 4-nitrobenzenesulfonateIC501170.0 [1]
(8-Ethylsulfonyloxy-4-methyl-2-oxochromen-7-yl) ethanesulfonateIC501940.0 [1]
(3-Cyano-4-methyl-2-oxochromen-7-yl) 2-nitrobenzenesulfonateIC501070.0 [1]
(3-Chloro-4-methyl-2-oxochromen-7-yl) 2-nitrobenzenesulfonateIC501250.0 [1]
(4-Methyl-8-octylsulfonyloxy-2-oxochromen-7-yl) octane-1-sulfonateIC50920.0 [1]
[8-(4-Chlorophenyl)sulfonyloxy-4-methyl-2-oxochromen-7-yl] 4-chlorobenzenesulfonateIC503690.0 [1]
(4-Methyl-2-oxochromen-7-yl) 4-chloro-3-nitrobenzenesulfonateIC502310.0 [1]
(3-Chloro-4-methyl-2-oxochromen-7-yl) 2,5-dichlorobenzenesulfonateIC501830.0 [1]
(3-Cyano-4-methyl-2-oxochromen-7-yl) 4-methoxybenzenesulfonateIC50580.0 [1]
(4-Methyl-2-oxochromen-7-yl) 2,4,5-trichlorobenzenesulfonateIC508370.0 [1]
(3-Chloro-4-methyl-2-oxochromen-7-yl) 4-methoxybenzenesulfonateIC509010.0 [1]
(3-Chloro-4-methyl-2-oxochromen-7-yl) octane-1-sulfonateIC502560.0 [1]
(3-Chloro-4-methyl-2-oxochromen-7-yl) 4-chlorobenzenesulfonateIC506380.0 [1]
(3-Cyano-4-methyl-2-oxochromen-7-yl) methanesulfonateIC501990.0 [1]
(4-Chloro-3,5-dimethylpyrazol-1-yl)-(4-methylphenyl)methanoneIC5017700.0 [1]
2-(3,4-Dimethylphenyl)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC50540.0 [1]
(3Z)-3-[(2-Methylphenyl)methylidene]-1,1-dioxo-1lambda6,2-benzothiazin-4-oneIC502360.0 [1]
2-(Prop-2-enylamino)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC50290.0 [1]
2-(Butylamino)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC50880.0 [1]
(3Z)-3-[(3-Fluorophenyl)methylidene]-1,1-dioxo-1lambda6,2-benzothiazin-4-oneIC503190.0 [1]
2-[Amino(methyl)amino]-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC502020.0 [1]
(3Z)-3-[(4-Chlorophenyl)methylidene]-1,1-dioxo-1lambda6,2-benzothiazin-4-oneIC50250.0 [1]
2-(3-Fluorophenyl)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC501390.0 [1]
2-(3-Nitrophenyl)-7-(trifluoromethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-oneIC50620.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Alkaline phosphatase, tissue-nonspecific isozyme Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/alkaline-phosphatase-tissue-nonspecific-isozyme-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Alkaline phosphatase, tissue-nonspecific isozyme Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/alkaline-phosphatase-tissue-nonspecific-isozyme-inhibitors-ic50-ki.
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