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Aldo-keto reductase family 1 member C4 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
3-((4-(Trifluoromethyl)Phenyl)Amino)Benzoic AcidIC5062700.0 [1]
3-[(4-Nitrophenyl)amino]benzoic AcidIC5032700.0 [1]
IndomethacinIC5054000.0 [1], 100000.0 [2]
Flufenamic acidIC50100000.0 [1]
Meclofenamic acidIC50100000.0 [1]
1-(4-Chlorobenzoyl)-5-methoxy-1H-indole-3-acetic acidIC5048.7 [1], 48700.0 [2]
1-[4-(3,4-Dihydro-1H-isoquinolin-2-ylsulfonyl)phenyl]pyrrolidin-2-oneIC5030000.0 [1]
3-(4-Acetylanilino)benzoic acidIC5025700.0 [1]
3-[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]propanoic acidIC50100.0 [1], 100000.0 [2]
2-[5-Methoxy-2-methyl-1-(4-methylbenzoyl)indol-3-yl]acetic acidIC50100.0 [1], 100000.0 [2]
9-(4-Chlorobenzoyl)-6-methoxy-1,2,3,4-tetrahydrocarbazole-3-carboxylic acidIC503.15 [1], 3150.0 [2]
3-[(4-Bromophenyl)Amino]Benzoic AcidIC5091400.0 [1]
3-(4-Tert-butylanilino)benzoic acidIC5039100.0 [1]
3-[(4-Chlorophenyl)Amino]Benzoic AcidIC5048700.0 [1]
2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-(trifluoromethylsulfonyl)acetamideIC50100.0 [1], 100000.0 [2]
1h-Indole-3-acetic acid,5-methoxy-2-methyl-1-[4-(trifluoromethyl)benzoyl]-IC50100.0 [1], 100000.0 [2]
3-[1-(4-Chlorobenzoyl)-5-methoxy-3-methylindol-2-yl]propanoic acidIC503.51 [1], 3510.0 [2]
3-[1-(4-Chlorobenzoyl)-5-methoxy-3-methylindol-2-yl]-N-methylsulfonylpropanamideIC5012.64 [1], 12640.0 [2]
3-[1-(4-Chlorobenzoyl)-3-ethyl-5-methoxyindol-2-yl]propanoic acidIC501.95 [1], 1950.0 [2]
2-[1-(4-Chlorobenzoyl)-5-methoxyindol-3-yl]-N-(trifluoromethylsulfonyl)acetamideIC50100.0 [1], 100000.0 [2]
1-[4-(Chloromethyl)benzoyl]-2-methyl-5-methoxy-1H-indole-3-acetic acidIC5049.75 [1], 49750.0 [2]
NaproxenIC50100000.0 [1]
Jasmonic acidKi37000.0 [1]
FlurbiprofenIC50100000.0 [1]
Mefenamic acidIC50100000.0 [1]
Caffeic acid phenethyl esterIC502300.0 [1]
DexibuprofenIC50100000.0 [1]
3,5-Dichlorosalicylic acidKi24000.0 [1]
3,5-Dibromosalicylic acidKi45700.0 [1]
3-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic acidIC5030000.0 [1]
1-[4-(Piperidine-1-sulfonyl)-phenyl]-pyrrolidin-2-oneIC5030000.0 [1]
5-Bromo-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acidKi18200.0 [1]
Morpholin-4-yl-(4-phenyl-piperazin-1-yl)-methanoneIC5030000.0 [1]
3-[(2-Phenylethyl)sulfamoyl]benzoic acidIC5030000.0 [1]
3-(1,3-Dihydro-isoindole-2-sulfonyl)-benzoic acidIC5030000.0 [1]
4-((3,4-Dihydroisoquinolin-2(1H)-yl)sulfonyl)benzoic acidIC5030000.0 [1]
4-(4-Chlorophenyl)piperazinyl piperidyl ketoneIC5030000.0 [1]
[4-(4-Fluoro-phenyl)-piperazin-1-yl]-morpholin-4-yl-methanoneIC5030000.0 [1]
(E)-3-[3-(3-Methylbut-2-enyl)-4-(3-phenylpropanoyloxy)phenyl]prop-2-enoic acidIC50102000.0 [1]
1-{4-[(2-Methylpiperidin-1-yl)sulfonyl]phenyl}pyrrolidin-2-oneIC5030000.0 [1]
[4-(4-Chlorophenyl)piperazin-1-yl](morpholin-4-yl)methanoneIC5030000.0 [1]
3-(3,4-Dihydroisoquinolin-2(1h)-Ylsulfonyl)-N-MethylbenzamideIC5030000.0 [1]
1-(4-Bromophenyl)sulfonylindole-3-carboxylic acidIC5030000.0 [1]
1-Naphthalen-2-ylsulfonylpyrrolidine-3-carboxylic acidIC5030000.0 [1]
3-(3,4-Dihydro-2H-quinoline-1-sulfonyl)-benzoic acidIC5030000.0 [1]
3-(Naphthalen-2-ylsulfamoyl)benzoic acidIC5030000.0 [1]
3-(3,4-Dihydro-1H-isoquinolin-2-ylsulfonyl)-N,N-dimethylbenzamideIC5030000.0 [1]
Morpholin-4-yl[4-(4-nitrophenyl)piperazin-1-yl]methanoneIC5030000.0 [1]
3-[(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-(2,3-Dihydro-indole-1-sulfonyl)-benzoic acidIC5030000.0 [1]
3-(3,4-Dihydro-1H-isoquinolin-2-ylsulfonyl)benzamideIC5030000.0 [1]
3-[2-(4-Methoxyphenyl)ethylsulfamoyl]benzoic acidIC5030000.0 [1]
3-[2-(4-Chlorophenyl)ethylsulfamoyl]benzoic acidIC5030000.0 [1]
3-[2-(2-Fluorophenyl)ethylsulfamoyl]benzoic acidIC5030000.0 [1]
3-[2-(3-Chlorophenyl)ethylsulfamoyl]benzoic acidIC5030000.0 [1]
3-[(4-Nitronaphthalen-1-Yl)amino]benzoic AcidIC508170.0 [1]
(S)-1-(Naphthalene-2-sulfonyl)-piperidine-3-carboxylic acidIC503000.0 [1]
(R)-1-(Naphthalene-2-sulfonyl)-piperidine-3-carboxylic acidIC5030000.0 [1]
1-[3-(2-Chlorophenyl)phenyl]sulfonylpiperidine-3-carboxylic acidIC5030000.0 [1]
1-[4-(3-Phenylphenyl)phenyl]sulfonylpiperidine-3-carboxylic acidIC5030000.0 [1]
3-[(7-Iodo-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-[(3-Methyl-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-[(5-Bromo-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
1-Anthracen-2-ylsulfonylpiperidine-3-carboxylic acidIC5030000.0 [1]
3-[(7-Chloro-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-[2-(4-Methylphenyl)ethylsulfamoyl]benzoic acidIC5030000.0 [1]
3-[(5-Hydroxy-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-[(6-Nitro-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-(3,4-Dihydro-1H-isoquinolin-2-ylsulfonyl)-N-(2-pyridin-4-ylethyl)benzamideIC5030000.0 [1]
3-[(5-Nitro-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-[(5-Chloro-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-[(5-Iodo-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-[(6-Methyl-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-[(6-Iodo-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-[(6-Methoxy-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-(3,4-Dihydro-1H-isoquinolin-2-ylsulfonyl)-N-[2-(dimethylamino)ethyl]benzamideIC5030000.0 [1]
3-[(7-Bromo-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
5-(3,4-Dihydro-1H-isoquinolin-2-ylsulfonyl)pyridine-3-carboxylic acidIC5030000.0 [1]
3-[(1-Methyl-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-[(6-Cyano-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-[(6-Chloro-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-[(6-Bromo-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
1-[4-(2-Chlorophenyl)phenyl]sulfonylpiperidine-3-carboxylic acidIC5030000.0 [1]
3-[(7-Nitro-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-[(6-Hydroxy-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
2-[3-(3,4-Dihydro-1H-isoquinolin-2-ylsulfonyl)anilino]-2-oxoacetic acidIC5030000.0 [1]
3-[(7-Methoxy-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-[(8-Chloro-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-[2-(3-Methylphenyl)ethylsulfamoyl]benzoic acidIC5030000.0 [1]
3-[(5-Amino-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-[(7-Ethynyl-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
[3-(3,4-Dihydro-1H-isoquinolin-2-ylsulfonyl)phenyl]-(2-oxa-6-azaspiro[3.3]heptan-6-yl)methanoneIC5030000.0 [1]
3-[(7-Cyano-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-[2-(3-Phenoxyphenyl)ethylsulfamoyl]benzoic acidIC5030000.0 [1]
3-[(7-Methyl-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
1-Naphthalen-2-ylsulfonylpyrazole-3-carboxylic acidIC5030000.0 [1]
3-[(7-Fluoro-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-[2-(3-Methoxyphenyl)ethylsulfamoyl]benzoic acidIC5030000.0 [1]
3-[(5-Methoxy-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
[4-(2,4-Dichlorophenyl)piperazin-1-yl]-morpholin-4-ylmethanoneIC5030000.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Aldo-keto reductase family 1 member C4 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/aldo-keto-reductase-family-1-member-c4-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Aldo-keto reductase family 1 member C4 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/aldo-keto-reductase-family-1-member-c4-inhibitors-ic50-ki.
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