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Aldo-keto reductase family 1 member C2 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
Flufenamic acidIC50530.0 [1]
IndomethacinIC5036530.0 [1], 75000.0 [2], 100000.0 [3]
IndomethacinKi100000.0 [1]
N-Phenylanthranilic acidIC50440.0 [1]
4-(Phenylamino)benzoic acidIC503000.0 [1]
3-((4-(Trifluoromethyl)Phenyl)Amino)Benzoic AcidIC5015000.0 [1], 15400.0 [2]
3-[(4-Nitrophenyl)amino]benzoic AcidIC503380.0 [1], 3400.0 [2]
3-(4-Acetylanilino)benzoic acidIC5019000.0 [1], 19500.0 [2]
3-((4-Methoxyphenyl)amino)benzoic acidIC5011000.0 [1], 11500.0 [2]
3-(Phenylamino)benzoic acidIC5012900.0 [1], 13000.0 [2]
3-[(4-Bromophenyl)Amino]Benzoic AcidIC5018000.0 [1], 18100.0 [2]
3-(4-Tert-butylanilino)benzoic acidIC5031000.0 [1], 31100.0 [2]
3-[(4-Methylphenyl)Amino]Benzoic AcidIC5056000.0 [1], 56200.0 [2]
3-[(4-Chlorophenyl)Amino]Benzoic AcidIC5019000.0 [1], 19100.0 [2]
Medroxyprogesterone acetateIC501600.0 [1], 4100.0 [2]
Jasmonic acidKi15000.0 [1], 18000.0 [2]
Mefenamic acidIC506970.0 [1]
Mefenamic acidKi220.0 [1]
Meclofenamic acidIC508740.0 [1]
3,5-Dichlorosalicylic acidKi70.0 [1]
5-Bromo-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acidKi87.0 [1]
1-(4-Chlorobenzoyl)-5-methoxy-1H-indole-3-acetic acidIC50100.0 [1], 100000.0 [2]
1-[4-(3,4-Dihydro-1H-isoquinolin-2-ylsulfonyl)phenyl]pyrrolidin-2-oneIC5030000.0 [1]
3-[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]propanoic acidIC5057.0 [1], 56530.0 [2]
2-[5-Methoxy-2-methyl-1-(4-methylbenzoyl)indol-3-yl]acetic acidIC5054.5 [1], 54500.0 [2]
5-Hydroxy-3-[(4-methoxyphenyl)methyl]-N-[3-(trifluoromethyl)phenyl]triazole-4-carboxamideIC5073230.0 [1]
9-(4-Chlorobenzoyl)-6-methoxy-1,2,3,4-tetrahydrocarbazole-3-carboxylic acidIC5053.5 [1], 53650.0 [2]
3a-Phenyl-3,4-dihydro-2H-pyrrolo[1,2-a]benzimidazol-1-oneIC5092300.0 [1]
3a-Phenyl-3,4-dihydro-2H-pyrrolo[1,2-a]benzimidazol-1-oneKi46200.0 [1]
2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-(trifluoromethylsulfonyl)acetamideIC5081.0 [1], 80950.0 [2]
1h-Indole-3-acetic acid,5-methoxy-2-methyl-1-[4-(trifluoromethyl)benzoyl]-IC5035.73 [1], 35730.0 [2]
2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(2-hydroxyphenyl)acetamideIC50205700.0 [1]
2-(2,4-Dioxo-1,3-thiazolidin-5-yl)-N-(2-hydroxyphenyl)acetamideKi102800.0 [1]
3-[1-(4-Chlorobenzoyl)-5-methoxy-3-methylindol-2-yl]propanoic acidIC5014.5 [1], 14450.0 [2]
3-[1-(4-Chlorobenzoyl)-5-methoxy-3-methylindol-2-yl]-N-methylsulfonylpropanamideIC5093.0 [1], 93000.0 [2]
3-[1-(4-Chlorobenzoyl)-3-ethyl-5-methoxyindol-2-yl]propanoic acidIC5049.57 [1], 49570.0 [2]
2-[1-(4-Chlorobenzoyl)-5-methoxyindol-3-yl]-N-(trifluoromethylsulfonyl)acetamideIC5050.13 [1], 50130.0 [2]
1-[4-(Chloromethyl)benzoyl]-2-methyl-5-methoxy-1H-indole-3-acetic acidIC5040.74 [1], 40740.0 [2]
DiazepamIC502400.0 [1]
NaproxenIC5031300.0 [1]
FlurbiprofenIC5032500.0 [1]
Caffeic acid phenethyl esterIC506000.0 [1]
DexibuprofenIC5042400.0 [1]
5-Methoxy-2-methyl-3-indoleacetic acidIC50100000.0 [1]
CloxazolamKi10000.0 [1]
2'-HydroxyflavoneIC5047100.0 [1]
3,5-Dibromosalicylic acidKi82.0 [1]
(E)-3-(4-Hydroxy-3-(3-methyl-2-butenyl)phenyl)-2-propenoic acidIC50108000.0 [1]
3-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic acidIC5030000.0 [1]
2-((4-Methoxyphenyl)amino)benzoic acidIC50700.0 [1]
1-[4-(Piperidine-1-sulfonyl)-phenyl]-pyrrolidin-2-oneIC5030000.0 [1]
N-[(2,6-Dioxo-4-phenylcyclohexylidene)methyl]glycineKi18200.0 [1]
3-[(2-Naphthylsulfonyl)amino]propanoic acidKi57300.0 [1]
Morpholin-4-yl-(4-phenyl-piperazin-1-yl)-methanoneIC5030000.0 [1]
Anthranilic acid, N-(3-methoxyphenyl)-IC501110.0 [1]
Anthranilic acid, N-p-nitrophenyl-IC50280.0 [1]
3-[(2-Phenylethyl)sulfamoyl]benzoic acidIC5030000.0 [1]
3-(1,3-Dihydro-isoindole-2-sulfonyl)-benzoic acidIC5030000.0 [1]
4-[Methyl(phenylsulfonyl)amino]benzoic acidKi119000.0 [1]
4-((3,4-Dihydroisoquinolin-2(1H)-yl)sulfonyl)benzoic acidIC5030000.0 [1]
4-(4-Chlorophenyl)piperazinyl piperidyl ketoneIC5030000.0 [1]
7-Benzoyl-4,5-dihydro-1,4-benzoxazepin-3(2H)-oneKi137000.0 [1]
3-(2-Carboxyethylamino)naphthalene-2-carboxylic acidKi33000.0 [1]
[4-(4-Fluoro-phenyl)-piperazin-1-yl]-morpholin-4-yl-methanoneIC5030000.0 [1]
5-Chloro-4-Hydroxybiphenyl-3-Carboxylic AcidKi21.0 [1]
N-(3-Carboxyphenyl)anthranilic acidIC504160.0 [1]
(E)-3-[3-(3-Methylbut-2-enyl)-4-(3-phenylpropanoyloxy)phenyl]prop-2-enoic acidIC50100000.0 [1]
2-[(4-Methylphenyl)amino]benzoic acidIC501460.0 [1]
Methyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetateIC50100000.0 [1]
1-{4-[(2-Methylpiperidin-1-yl)sulfonyl]phenyl}pyrrolidin-2-oneIC5030000.0 [1]
N-(3-Methylphenyl)anthranilic acidIC50380.0 [1]
[4-(4-Chlorophenyl)piperazin-1-yl](morpholin-4-yl)methanoneIC5030000.0 [1]
[1-(4-Fluorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acidIC5060970.0 [1]
3-(3,4-Dihydroisoquinolin-2(1h)-Ylsulfonyl)-N-MethylbenzamideIC5030000.0 [1]
2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-methylsulfonylacetamideIC5065390.0 [1]
1-(4-Bromophenyl)sulfonylindole-3-carboxylic acidIC5030000.0 [1]
N-(2-Methoxyphenyl)anthranilic acidIC501280.0 [1]
1-Naphthalen-2-ylsulfonylpyrrolidine-3-carboxylic acidIC5030000.0 [1]
5-Bromo-3-phenylsalicylic acidKi1970.0 [1]
3-(3,4-Dihydro-2H-quinoline-1-sulfonyl)-benzoic acidIC5030000.0 [1]
2-Methyl-1-{1-[(5-methyl-1H-indol-2-yl)carbonyl]piperidin-4-yl}propan-2-olIC5020000.0 [1]
3-(Naphthalen-2-ylsulfamoyl)benzoic acidIC5030000.0 [1]
3-(3,4-Dihydro-1H-isoquinolin-2-ylsulfonyl)-N,N-dimethylbenzamideIC5030000.0 [1]
Morpholin-4-yl[4-(4-nitrophenyl)piperazin-1-yl]methanoneIC5030000.0 [1]
3-[(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-(2,3-Dihydro-indole-1-sulfonyl)-benzoic acidIC5030000.0 [1]
3-(3,4-Dihydro-1H-isoquinolin-2-ylsulfonyl)benzamideIC5030000.0 [1]
(E)-2-(4-Fluorophenyl)-3-(4-methylsulfonylphenyl)prop-2-enoic acidIC5044600.0 [1]
(E)-3-(4-Methylsulfonylphenyl)-2-phenylprop-2-enoic acidIC5034400.0 [1]
3-[2-(4-Methoxyphenyl)ethylsulfamoyl]benzoic acidIC5030000.0 [1]
3-[2-(4-Chlorophenyl)ethylsulfamoyl]benzoic acidIC5030000.0 [1]
3-[2-(2-Fluorophenyl)ethylsulfamoyl]benzoic acidIC5030000.0 [1]
3-[2-(3-Chlorophenyl)ethylsulfamoyl]benzoic acidIC5030000.0 [1]
2-(4-Chloroanilino)benzoic acidIC50410.0 [1]
5-Fluoro-4-hydroxybiphenyl-3-carboxylic acidKi1.5 [1]
3-[(4-Nitronaphthalen-1-Yl)amino]benzoic AcidIC508170.0 [1]
(S)-1-(Naphthalene-2-sulfonyl)-piperidine-3-carboxylic acidIC503000.0 [1]
(R)-1-(Naphthalene-2-sulfonyl)-piperidine-3-carboxylic acidIC5030000.0 [1]
1-[3-(2-Chlorophenyl)phenyl]sulfonylpiperidine-3-carboxylic acidIC5030000.0 [1]
1-[4-(3-Phenylphenyl)phenyl]sulfonylpiperidine-3-carboxylic acidIC5030000.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Aldo-keto reductase family 1 member C2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/aldo-keto-reductase-family-1-member-c2-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 22). Quest Database™ Aldo-keto reductase family 1 member C2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/aldo-keto-reductase-family-1-member-c2-inhibitors-ic50-ki.
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