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Aldo-keto reductase family 1 member C1 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
3,5-Dichlorosalicylic acidIC506.0 [1]
3,5-Dichlorosalicylic acidKi58.0 [1]
5-Chloro-4-Hydroxybiphenyl-3-Carboxylic AcidIC50100.0 [1]
5-Chloro-4-Hydroxybiphenyl-3-Carboxylic AcidKi1.5 [1]
5-Bromo-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acidIC50460.0 [1]
5-Bromo-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acidKi4.0 [1], 4.1 [2], 14.0 [3], 113.0 [4]
IndomethacinIC50100000.0 [1], 130000.0 [2]
IndomethacinKi100000.0 [1]
Flufenamic acidIC50980.0 [1], 2640.0 [2]
Meclofenamic acidIC50740.0 [1], 3160.0 [2]
3-((4-(Trifluoromethyl)Phenyl)Amino)Benzoic AcidIC5022700.0 [1]
3-[(4-Nitrophenyl)amino]benzoic AcidIC506740.0 [1]
Medroxyprogesterone acetateIC50700.0 [1], 1800.0 [2]
Jasmonic acidKi106000.0 [1]
Mefenamic acidIC503910.0 [1]
Mefenamic acidKi810.0 [1]
3,5-Dibromosalicylic acidIC502300.0 [1]
3,5-Dibromosalicylic acidKi9.0 [1]
1-(4-Chlorobenzoyl)-5-methoxy-1H-indole-3-acetic acidIC50100.0 [1], 100000.0 [2]
1-[4-(3,4-Dihydro-1H-isoquinolin-2-ylsulfonyl)phenyl]pyrrolidin-2-oneIC5030000.0 [1]
3-(4-Acetylanilino)benzoic acidIC5015600.0 [1]
3-[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]propanoic acidIC50100.0 [1], 100000.0 [2]
2-[5-Methoxy-2-methyl-1-(4-methylbenzoyl)indol-3-yl]acetic acidIC50100.0 [1], 100000.0 [2]
9-(4-Chlorobenzoyl)-6-methoxy-1,2,3,4-tetrahydrocarbazole-3-carboxylic acidIC5076.25 [1], 76250.0 [2]
3a-Phenyl-3,4-dihydro-2H-pyrrolo[1,2-a]benzimidazol-1-oneIC50167200.0 [1]
3a-Phenyl-3,4-dihydro-2H-pyrrolo[1,2-a]benzimidazol-1-oneKi83600.0 [1]
5-Fluoro-4-hydroxybiphenyl-3-carboxylic acidIC50300.0 [1]
5-Fluoro-4-hydroxybiphenyl-3-carboxylic acidKi1.3 [1]
3-[(4-Bromophenyl)Amino]Benzoic AcidIC5031300.0 [1]
3-(4-Tert-butylanilino)benzoic acidIC5035600.0 [1]
3-[(4-Chlorophenyl)Amino]Benzoic AcidIC5030200.0 [1]
2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-(trifluoromethylsulfonyl)acetamideIC50100.0 [1], 100000.0 [2]
1h-Indole-3-acetic acid,5-methoxy-2-methyl-1-[4-(trifluoromethyl)benzoyl]-IC50100.0 [1], 100000.0 [2]
3-[1-(4-Chlorobenzoyl)-5-methoxy-3-methylindol-2-yl]propanoic acidIC5017.73 [1], 17730.0 [2]
3-[1-(4-Chlorobenzoyl)-5-methoxy-3-methylindol-2-yl]-N-methylsulfonylpropanamideIC50100.0 [1], 100000.0 [2]
3-[1-(4-Chlorobenzoyl)-3-ethyl-5-methoxyindol-2-yl]propanoic acidIC5030.71 [1], 30710.0 [2]
2-[1-(4-Chlorobenzoyl)-5-methoxyindol-3-yl]-N-(trifluoromethylsulfonyl)acetamideIC50100.0 [1], 100000.0 [2]
1-[4-(Chloromethyl)benzoyl]-2-methyl-5-methoxy-1H-indole-3-acetic acidIC50100.0 [1], 100000.0 [2]
DiazepamIC505600.0 [1]
NaproxenIC50100000.0 [1]
FlurbiprofenIC50100000.0 [1]
Caffeic acid phenethyl esterIC5013000.0 [1]
BenzbromaroneIC5048.0 [1]
DexibuprofenIC50100000.0 [1]
CloxazolamKi10000.0 [1]
2'-HydroxyflavoneIC506200.0 [1]
3-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic acidIC5020300.0 [1]
1-[4-(Piperidine-1-sulfonyl)-phenyl]-pyrrolidin-2-oneIC5030000.0 [1]
N-[(2,6-Dioxo-4-phenylcyclohexylidene)methyl]glycineKi56000.0 [1]
N-(4-(Cyano(Phenyl)Methyl)Phenyl)AcetamideKi89000.0 [1]
3-[(2-Naphthylsulfonyl)amino]propanoic acidKi103000.0 [1]
alpha-Phenylcinnamic acidIC507900.0 [1]
Morpholin-4-yl-(4-phenyl-piperazin-1-yl)-methanoneIC5030000.0 [1]
3-[(2-Phenylethyl)sulfamoyl]benzoic acidIC5030000.0 [1]
3-(1,3-Dihydro-isoindole-2-sulfonyl)-benzoic acidIC503890.0 [1]
4-[Methyl(phenylsulfonyl)amino]benzoic acidKi124000.0 [1]
4-((3,4-Dihydroisoquinolin-2(1H)-yl)sulfonyl)benzoic acidIC5030000.0 [1]
4-(4-Chlorophenyl)piperazinyl piperidyl ketoneIC5030000.0 [1]
6-Amino-4-(4-hydroxy-3-methoxyphenyl)-3-propyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrileIC502490.0 [1]
TetrabromophenolphthaleinIC5033.0 [1]
1-Phenylcyclopentanecarboxylic acidIC5072900.0 [1]
7-Benzoyl-4,5-dihydro-1,4-benzoxazepin-3(2H)-oneKi66000.0 [1]
3-(2-Carboxyethylamino)naphthalene-2-carboxylic acidKi19000.0 [1]
[4-(4-Fluoro-phenyl)-piperazin-1-yl]-morpholin-4-yl-methanoneIC5030000.0 [1]
(E)-3-[3-(3-Methylbut-2-enyl)-4-(3-phenylpropanoyloxy)phenyl]prop-2-enoic acidIC50100000.0 [1]
1-{4-[(2-Methylpiperidin-1-yl)sulfonyl]phenyl}pyrrolidin-2-oneIC5030000.0 [1]
[4-(4-Chlorophenyl)piperazin-1-yl](morpholin-4-yl)methanoneIC5030000.0 [1]
3-(3,4-Dihydroisoquinolin-2(1h)-Ylsulfonyl)-N-MethylbenzamideIC5030000.0 [1]
1-(4-Bromophenyl)sulfonylindole-3-carboxylic acidIC50830.0 [1]
1-Naphthalen-2-ylsulfonylpyrrolidine-3-carboxylic acidIC5022200.0 [1]
5-Bromo-3-phenylsalicylic acidKi140.0 [1]
3-(3,4-Dihydro-2H-quinoline-1-sulfonyl)-benzoic acidIC5030000.0 [1]
3-(Naphthalen-2-ylsulfamoyl)benzoic acidIC5030000.0 [1]
3-(3,4-Dihydro-1H-isoquinolin-2-ylsulfonyl)-N,N-dimethylbenzamideIC5030000.0 [1]
Morpholin-4-yl[4-(4-nitrophenyl)piperazin-1-yl]methanoneIC5030000.0 [1]
3-[(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-(2,3-Dihydro-indole-1-sulfonyl)-benzoic acidIC506610.0 [1]
3-(3,4-Dihydro-1H-isoquinolin-2-ylsulfonyl)benzamideIC5030000.0 [1]
(E)-2-(4-Fluorophenyl)-3-(4-methylsulfonylphenyl)prop-2-enoic acidIC5023300.0 [1]
(E)-3-(4-Methylsulfonylphenyl)-2-phenylprop-2-enoic acidIC5030800.0 [1]
3-[2-(4-Methoxyphenyl)ethylsulfamoyl]benzoic acidIC5030000.0 [1]
3-[2-(4-Chlorophenyl)ethylsulfamoyl]benzoic acidIC5030000.0 [1]
3-[2-(2-Fluorophenyl)ethylsulfamoyl]benzoic acidIC5030000.0 [1]
3-[2-(3-Chlorophenyl)ethylsulfamoyl]benzoic acidIC5030000.0 [1]
3-[(4-Nitronaphthalen-1-Yl)amino]benzoic AcidIC5011100.0 [1]
(S)-1-(Naphthalene-2-sulfonyl)-piperidine-3-carboxylic acidIC5030000.0 [1]
(R)-1-(Naphthalene-2-sulfonyl)-piperidine-3-carboxylic acidIC5030000.0 [1]
1-[3-(2-Chlorophenyl)phenyl]sulfonylpiperidine-3-carboxylic acidIC5030000.0 [1]
1-[4-(3-Phenylphenyl)phenyl]sulfonylpiperidine-3-carboxylic acidIC50730.0 [1]
3-[(7-Iodo-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-[(3-Methyl-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-[(5-Bromo-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
1-Anthracen-2-ylsulfonylpiperidine-3-carboxylic acidIC5030000.0 [1]
3-[(7-Chloro-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-[2-(4-Methylphenyl)ethylsulfamoyl]benzoic acidIC5030000.0 [1]
3-[(5-Hydroxy-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5025600.0 [1]
3-[(6-Nitro-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
3-(3,4-Dihydro-1H-isoquinolin-2-ylsulfonyl)-N-(2-pyridin-4-ylethyl)benzamideIC5030000.0 [1]
3-[(5-Nitro-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5024600.0 [1]
3-[(5-Chloro-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]benzoic acidIC5030000.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Aldo-keto reductase family 1 member C1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/aldo-keto-reductase-family-1-member-c1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Aldo-keto reductase family 1 member C1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/aldo-keto-reductase-family-1-member-c1-inhibitors-ic50-ki.
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