Advanced glycosylation end product-specific receptor Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Fps-ZM1	Ki	25.0 [1], 148.0 [2], 230.0 [3]
	2-(Diethylamino)ethyl 4-[[(2R)-2-amino-3-naphthalen-2-ylpropanoyl]amino]-3-butoxybenzoate	IC50	1750.0 [1], 2290.0 [2], 3400.0 [3]
	Tert-butyl N-[(1R)-1-[1-butyl-5-[3-(diethylamino)propoxy]benzimidazol-2-yl]-2-[4-[2-(4-chlorophenyl)ethoxy]phenyl]ethyl]carbamate	IC50	500.0 [1]
	9H-Fluoren-9-ylmethyl N-[3-(1-benzylpiperidin-4-yl)-1-[2-butoxy-4-[3-(diethylamino)propoxy]anilino]-1-oxopropan-2-yl]carbamate	IC50	500.0 [1]
	4,6-Bis(4-chlorophenyl)-N-[3-[2-(diethylamino)ethoxy]phenyl]pyrimidin-2-amine	IC50	16500.0 [1]
	N-[2-Butoxy-4-[3-(diethylamino)propoxy]phenyl]-5-[4-(4-fluorophenoxy)phenyl]-2-methylpyrazole-3-carboxamide	IC50	1900.0 [1]
	4-Butyl-2-[4-(4-chlorophenoxy)phenyl]-5-[4-[(1-ethylpiperidin-3-yl)methoxy]phenyl]-1,3-thiazole	IC50	1140.0 [1]
	5-Butyl-4-[4-(4-chlorophenoxy)phenyl]-2-[4-[3-(4-methylpiperazin-1-yl)propoxy]phenyl]-1,3-thiazole	IC50	1240.0 [1]
	5-Butyl-4-[4-(4-chlorophenoxy)phenyl]-2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-1,3-thiazole	IC50	910.0 [1]
	2-[4-[5-Butyl-4-[4-(4-chlorophenoxy)phenyl]-1,3-thiazol-2-yl]phenoxy]-N,N-diethylethanamine	IC50	1580.0 [1]
	3-[4-[5-Butyl-2-[4-(4-chlorophenoxy)phenyl]-1,3-thiazol-4-yl]phenoxy]-N,N-diethylpropan-1-amine	IC50	1120.0 [1]
	4,6-Bis(4-chlorophenyl)-N-[2-[2-(diethylamino)ethoxy]phenyl]pyrimidin-2-amine	IC50	4600.0 [1]
	5-Butyl-4-[4-(4-chlorophenoxy)phenyl]-2-[4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-1,3-thiazole	IC50	1210.0 [1]
	5-Butyl-2-[4-(4-chlorophenoxy)phenyl]-4-[4-[(1-ethylpiperidin-3-yl)methoxy]phenyl]-1,3-thiazole	IC50	1910.0 [1]
	3-[4-[5-Butyl-4-[4-(4-chlorophenoxy)phenyl]-1,3-thiazol-2-yl]phenoxy]-N,N-diethylpropan-1-amine	IC50	1720.0 [1]
	5-Butyl-4-[4-(4-chlorophenoxy)phenyl]-2-[4-(2-piperidin-1-ylethoxy)phenyl]-1,3-thiazole	IC50	1040.0 [1]
	2-[4-[5-Butyl-4-[4-(4-chlorophenoxy)phenyl]-1,3-thiazol-2-yl]phenoxy]-N,N-dimethylethanamine	IC50	3180.0 [1]
	5-Butyl-4-[4-(4-chlorophenoxy)phenyl]-2-[4-[(1-ethylpiperidin-3-yl)methoxy]phenyl]-1,3-thiazole	IC50	660.0 [1]
	5-Butyl-4-[4-(4-chlorophenoxy)phenyl]-2-[4-(3-piperidin-1-ylpropoxy)phenyl]-1,3-thiazole	IC50	1840.0 [1]
	3-[4-[4-Butyl-2-[4-(4-chlorophenoxy)phenyl]-1,3-thiazol-5-yl]phenoxy]-N,N-diethylpropan-1-amine	IC50	2010.0 [1]
	N-[2-Butoxy-4-[3-(diethylamino)propoxy]phenyl]-2-methyl-5-(4-phenoxyphenyl)pyrazole-3-carboxamide	IC50	5400.0 [1]
	N-[2-Butoxy-4-[3-(diethylamino)propoxy]phenyl]-5-(4-cyclohexyloxyphenyl)-2-methylpyrazole-3-carboxamide	IC50	2500.0 [1]
	N-[2-Butoxy-4-[3-(diethylamino)propoxy]phenyl]-2-methyl-5-[4-[4-(trifluoromethyl)phenoxy]phenyl]pyrazole-3-carboxamide	IC50	1900.0 [1]
	N-[2-Butoxy-4-[3-(diethylamino)propoxy]phenyl]-2-methyl-5-(4-pyridin-2-yloxyphenyl)pyrazole-3-carboxamide	IC50	18900.0 [1]
	N-[2-Butoxy-4-[3-(diethylamino)propoxy]phenyl]-5-[4-(4-methoxyphenoxy)phenyl]-2-methylpyrazole-3-carboxamide	IC50	7800.0 [1]
	N-[2-Butoxy-4-[3-(diethylamino)propoxy]phenyl]-5-[4-(4-chloro-3-methoxyphenoxy)phenyl]-2-methylpyrazole-3-carboxamide	IC50	5300.0 [1]
	5-Butyl-4-[4-(4-chlorophenoxy)phenyl]-N-[4-[3-(diethylamino)propoxy]phenyl]-1,3-thiazol-2-amine;trihydrochloride	IC50	550.0 [1]
	N-[5-Butyl-4-[4-(4-chlorophenoxy)phenyl]-1,3-thiazol-2-yl]-4-[3-(diethylamino)propoxy]benzamide	IC50	5590.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

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References

This online tool may be cited as follows

MLA	"Quest Database™ Advanced glycosylation end product-specific receptor Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Dec. 2024, https://www.aatbio.com/data-sets/advanced-glycosylation-end-product-specific-receptor-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, December 21). Quest Database™ Advanced glycosylation end product-specific receptor Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/advanced-glycosylation-end-product-specific-receptor-inhibitors-ic50-ki.
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