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Adrenergic receptor beta Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
PropranololIC504.0 [1], 12.0 [2]
OlanzapineKi10000.0 [1]
SotalolIC507200.0 [1]
CisaprideIC5010000.0 [1]
Sotalol hydrochlorideIC507200.0 [1]
AlprenololIC502.3 [1]
ZafirlukastIC5010000.0 [1]
SematilideIC507000000.0 [1]
4-Amino-5-chloro-N-((hexahydro-1H-pyrrolizin-1-yl)methyl)-2-methoxybenzamide hydrochlorideKi10000.0 [1]
NaluzotanKi2000.0 [1]
N-DesmethylolanzapineKi10000.0 [1]
4-(3-Tert-Butylamino-propoxy)-3-methyl-benzofuran-2-carboxylic acid ethyl esterIC5025000.0 [1]
2-Hydroxymethyl OlanzapineKi10000.0 [1]
Ethyl 4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-1-benzofuran-2-carboxylateIC5098.0 [1]
Ethyl 3-methyl-4-{3-[(methylethyl)amino]propoxy}benzo[d]furan-2-carboxylateIC5038000.0 [1]
Ethyl 4-{3-[(tert-butyl)amino]-2-hydroxypropoxy}-3-methylbenzo[d]furan-2-carboxylateIC504.3 [1]
4-Amino-N-[(4R)-1-azatricyclo[3.3.1.03,7]nonan-4-yl]-5-chloro-2-methoxybenzamideIC5010000.0 [1]
N-[2-[(2-Hydroxy-3-naphthalen-1-yloxypropyl)amino]ethyl]-4-(methanesulfonamido)benzamideIC50150.0 [1]
N-[2-[[2-Hydroxy-3-(4-methoxyphenoxy)propyl]amino]ethyl]-4-(methanesulfonamido)benzamideIC5043800.0 [1]
N-[2-[(2-Hydroxy-3-phenoxypropyl)amino]ethyl]-4-(methanesulfonamido)benzamideIC503900.0 [1]
N-[2-[[3-(2-Cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-4-(methanesulfonamido)benzamideIC502900.0 [1]
N-[2-[(2-Hydroxy-3-phenoxypropyl)amino]cyclohexyl]-4-(methanesulfonamido)benzamideIC50192000.0 [1]
N-[2-[[2-Hydroxy-3-[4-(2-methoxyethyl)phenoxy]propyl]amino]ethyl]-4-imidazol-1-ylbenzamideIC5012400.0 [1]
N-[2-[[2-Hydroxy-3-(4-methoxyphenoxy)propyl]amino]ethyl]-4-imidazol-1-ylbenzamideIC5061400.0 [1]
N-[2-[(2-Hydroxy-3-naphthalen-1-yloxypropyl)amino]ethyl]-4-imidazol-1-ylbenzamideIC50420.0 [1]
N-[2-[[2-Hydroxy-3-[4-(methanesulfonamido)phenoxy]propyl]amino]ethyl]-4-imidazol-1-ylbenzamideIC50227000.0 [1]
1-[2-Hydroxy-3-(1-naphthalenyloxy)propyl]-4-[4-[(methylsulfonyl)amino]benzoyl]piperazineIC5030900.0 [1]
1-[4-(Methylsulfonylamino)benzoyl]-4-[2-hydroxy-3-phenoxypropyl]piperazineIC5012200.0 [1]
1-[4-(Methylsulfonylamino)benzoyl]-4-[2-hydroxy-3-[4-(2-methoxyethyl)phenoxy]propyl]piperazineIC50360000.0 [1]
1-[4-(Methylsulfonylamino)benzylamino]-3-(3-methylphenoxy)-2-propanolIC50990.0 [1]
1-[4-(Methylsulfonylamino)benzylamino]-3-phenoxy-2-propanolIC502900.0 [1]
1-[4-(Methylsulfonylamino)benzylamino]-3-[4-(2-methoxyethyl)phenoxy]-2-propanolIC5025800.0 [1]
1-(4-Imidazol-1-yl-benzylamino)-3-o-tolyloxy-propan-2-olIC50780.0 [1]
1-[4-[4-(Methylsulfonylamino)phenyl]-1-piperazinyl]-3-phenoxy-2-propanolIC5015800.0 [1]
1-[4-[4-(Methylsulfonylamino)phenyl]-1-piperazinyl]-3-(3-methylphenoxy)-2-propanolIC5015700.0 [1]
1-[4-[4-(Methylsulfonylamino)phenyl]-1-piperazinyl]-3-[4-(2-methoxyethyl)phenoxy]-2-propanolIC50109000.0 [1]
N-[4-[2-Hydroxy-3-[4-[4-(methanesulfonamido)phenyl]piperazin-1-yl]propoxy]phenyl]acetamideIC50293000.0 [1]
N-[4-[4-[2-Hydroxy-3-[(5-oxo-7,8-dihydro-6H-naphthalen-1-yl)oxy]propyl]piperazin-1-yl]phenyl]methanesulfonamideIC508400.0 [1]
1-[4-[4-(Methylsulfonylamino)phenyl]-1-piperazinyl]-3-(2-methylphenoxy)-2-propanolIC502300.0 [1]
1-[[2-[4-(1H-Imidazol-1-yl)phenoxy]ethyl]amino]-3-phenoxy-2-propanolIC5040.0 [1]
1-[[2-[4-(1H-Imidazol-1-yl)phenoxy]ethyl]amino]-3-[4-(2-methoxyethyl)phenoxy]-2-propanolIC50270.0 [1]
1-{2-[4-(3H-Imidazol-1-yl)-phenoxy]-ethylamino}-3-m-tolyloxy-propan-2-olIC5090.0 [1]
2-[2-[4-(1H-Imidazol-1-yl)phenoxy]ethylamino]-1-[4-(methylsulfonylamino)phenyl]ethanolIC503600.0 [1]
alpha-[[[2-[4-(1H-Imidazol-1-yl)phenoxy]ethyl]amino]methyl]-2-methoxybenzenemethanolIC503700.0 [1]
4-Amino-N-(1-azatricyclo[3.3.1.13,7]decan-4-yl)-5-chloro-2-methoxybenzamideIC5010000.0 [1]
N-[4-[4-[3-(Dicyclopropylmethylamino)oxy-2-hydroxypropyl]piperazin-1-yl]phenyl]methanesulfonamideIC5015700.0 [1]
1-(Dicyclopropylmethylamino)oxy-3-[2-(4-imidazol-1-ylphenoxy)ethylamino]propan-2-olIC50300.0 [1]
(5R)-3-(3-Methyl-1-benzofuran-5-yl)spiro[1,3-oxazolidine-5,3'-1-azabicyclo[2.2.2]octane]-2-oneIC5010000.0 [1]
1-[2-Hydroxy-2-[4-[(methylsulfonyl)amino]phenyl]ethyl]-3-methyl-1H-imidazol-3-iumIC502350000.0 [1]
4-Amino-N-(1-azatricyclo[3.3.1.03,7]nonan-4-yl)-5-chloro-2-methoxybenzamideIC5010000.0 [1]
4-Amino-N-(1-azatricyclo[3.3.1.13,7]decan-4-ylmethyl)-5-chloro-2-methoxybenzamideIC5010000.0 [1]
Olanzapine N-OxideKi10000.0 [1]
5-Fluoro-2-[(E)-2-[3-[[4-(2-methylimidazo[4,5-c]pyridin-1-yl)phenoxy]methyl]phenyl]ethenyl]-1,3-benzothiazoleIC5010000.0 [1]
7-Chloro-2-[(E)-2-[3-[[4-(2-methylimidazo[4,5-c]pyridin-1-yl)phenoxy]methyl]phenyl]ethenyl]quinolineIC5010000.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Adrenergic receptor beta Inhibitors (IC50, Ki)." AAT Bioquest, Inc.22 Dec2024https://www.aatbio.com/data-sets/adrenergic-receptor-beta-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 22). Quest Database™ Adrenergic receptor beta Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/adrenergic-receptor-beta-inhibitors-ic50-ki.
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