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Adenylate cyclase type V Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
6-Amino-9H-purine-9-butanehydroximic acidIC507900.0 [1]
5-(6-Aminopurin-9-yl)-N-hydroxypentanamideIC507600.0 [1]
6-(6-Aminopurin-9-yl)-N-hydroxyhexanamideIC5035400.0 [1]
2-[3-(6-Amino-9H-purine-9-yl)propoxy]acetohydroximic acidIC5094000.0 [1]
2-(1-Naphthalen-1-ylsulfonylindol-6-yl)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazineIC507.2 [1]
5-(6-Aminopurin-9-yl)pentanoic acidIC50200000.0 [1]
2-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyloxy]-N-hydroxy-acetamideIC5013600.0 [1]
{[2-(6-Amino-purin-9-yl)-ethyl]-tert-butoxycarbonyl-amino}-acetic acid methyl esterIC50200000.0 [1]
(1R,3R)-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl]-acetic acidIC50200000.0 [1]
(1R,3S)-3-(6-Aminopurin-9-yl)-N-hydroxycyclopentane-1-carboxamideIC504600.0 [1]
(1R,3S)-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl]-acetic acidIC50200000.0 [1]
(1S,3S)-3-(6-Aminopurin-9-yl)-N-hydroxycyclopentane-1-carboxamideIC50200.0 [1]
(1S,3S)-[3-(6-Amino-purin-9-yl)-cyclopentyl]-acetic acidIC50100000.0 [1]
(1R,3R)-2-[3-(6-Amino-purin-9-yl)-cyclopentyl]-N-hydroxy-acetamideIC50600.0 [1]
(1S,3R)-[3-(6-Amino-purin-9-yl)-cyclopentyl]-acetic acidIC50200000.0 [1]
(1R,3R)-2-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl]-N-hydroxy-acetamideIC5016300.0 [1]
(1R,4R)-4-(6-Aminopurin-9-yl)-N-hydroxycyclopent-2-ene-1-carboxamideIC504900.0 [1]
(1S,3R)-2-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl]-N-hydroxy-acetamideIC50400.0 [1]
(1S,3S)-2-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl]-N-hydroxy-acetamideIC502600.0 [1]
(1R,3S)-[3-(6-Amino-purin-9-yl)-cyclopentyl]-acetic acidIC50200000.0 [1]
(1S,4R)-4-(6-Aminopurin-9-yl)-N-hydroxycyclopent-2-ene-1-carboxamideIC50188000.0 [1]
(1R,3R)-[3-(6-Amino-purin-9-yl)-cyclopentyl]-acetic acidIC5028800.0 [1]
(1S,3R)-2-[3-(6-Amino-purin-9-yl)-cyclopentyl]-N-hydroxy-acetamideIC5055000.0 [1]
(1R,3S)-2-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl]-N-hydroxy-acetamideIC504300.0 [1]
(1S,4S)-4-(6-Aminopurin-9-yl)-N-hydroxycyclopent-2-ene-1-carboxamideIC50100000.0 [1]
(1S,3R)-3-(6-Aminopurin-9-yl)-N-hydroxycyclopentane-1-carboxamideIC5070000.0 [1]
2-[(1S,4R)-4-(6-Aminopurin-9-yl)cyclopent-2-en-1-yl]acetic acidIC508200.0 [1]
(1S,3S)-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl]-acetic acidIC5073200.0 [1]
(1S,3S)-2-[3-(6-Amino-purin-9-yl)-cyclopentyl]-N-hydroxy-acetamideIC509400.0 [1]
(1R,4S)-4-(6-Aminopurin-9-yl)-N-hydroxycyclopent-2-ene-1-carboxamideIC50200000.0 [1]
(1R,3S)-2-[3-(6-Amino-purin-9-yl)-cyclopentyl]-N-hydroxy-acetamideIC5025100.0 [1]
7-(6-Amino-purin-9-yl)-heptanoic acidIC50200000.0 [1]
6-(6-Amino-purin-9-yl)-hexanoic acidIC50200000.0 [1]
6-Amino-9H-purine-9-propanehydroximic acidIC50200000.0 [1]
{Acetyl-[2-(6-amino-purin-9-yl)-ethyl]-amino}-acetic acidIC50200000.0 [1]
7-(6-Aminopurin-9-yl)-N-hydroxyheptanamideIC50200000.0 [1]
2-[Methyl[2-(6-amino-9H-purine-9-yl)ethyl]amino]acetohydroximic acidIC5015300.0 [1]
{[2-(6-Amino-purin-9-yl)-ethyl]-methyl-amino}-acetic acid methyl esterIC50200000.0 [1]
6-Amino-9H-purine-9-valeric acid methyl esterIC50200000.0 [1]
6-(6-Amino-purin-9-yl)-hexanoic acid ethyl esterIC50200000.0 [1]
N-[2-(6-Amino-purin-9-yl)-ethyl]-N-hydroxycarbamoylmethyl-acetamideIC50200000.0 [1]
[3-(6-Amino-purin-9-yl)-propylamino]-acetic acid methyl esterIC50200000.0 [1]
[2-(6-Amino-purin-9-yl)-ethylamino]-acetic acid methyl esterIC50200000.0 [1]
{Acetyl-[2-(6-amino-purin-9-yl)-ethyl]-amino}-acetic acid methyl esterIC50200000.0 [1]
2-[3-(6-Amino-9H-purine-9-yl)propylamino]acetohydroximic acidIC50200000.0 [1]
[3-(6-Amino-purin-9-yl)-propylamino]-acetic acidIC50200000.0 [1]
[2-(6-Amino-purin-9-yl)-ethylamino]-acetic acidIC50200000.0 [1]
2-[Tert-Butoxycarbonyl[3-(6-amino-9H-purine-9-yl)propyl]amino]acetohydroximic acidIC50200000.0 [1]
2-[2-(6-Amino-9H-purine-9-yl)ethylamino]acetohydroximic acidIC50200000.0 [1]
[3-(6-Amino-purin-9-yl)-propoxy]-acetic acidIC50140500.0 [1]
[3-(6-Amino-purin-9-yl)-propoxy]-acetic acid ethyl esterIC50200000.0 [1]
{[3-(6-Amino-purin-9-yl)-propyl]-tert-butoxycarbonyl-amino}-acetic acidIC50200000.0 [1]
{[2-(6-Amino-purin-9-yl)-ethyl]-tert-butoxycarbonyl-amino}-acetic acidIC50200000.0 [1]
2-[Tert-Butoxycarbonyl[2-(6-amino-9H-purine-9-yl)ethyl]amino]acetohydroximic acidIC50200000.0 [1]
7-(6-Amino-purin-9-yl)-heptanoic acid ethyl esterIC50200000.0 [1]
[[(1R,4R)-4-(6-Amino-9H-purine-9-yl)cyclopentyl]oxy]acetic acidIC50200000.0 [1]
[[(1R,4R)-4-(6-Amino-9H-purine-9-yl)-2-cyclopentene-1-yl]oxy]acetic acidIC50200000.0 [1]
[[(1S,4S)-4-(6-Amino-9H-purine-9-yl)cyclopentyl]oxy]acetic acidIC50200000.0 [1]
[[(1S,4S)-4-(6-Amino-9H-purine-9-yl)-2-cyclopentene-1-yl]oxy]acetic acidIC5072000.0 [1]
2-[(R)-3-((R)-6-Amino-purin-9-yl)-cyclopentyloxy]-N-hydroxy-acetamideIC50110000.0 [1]
2-[[(1S,4R)-4-(6-Amino-9H-purine-9-yl)-2-cyclopentene-1-yl]oxy]acetohydroximic acidIC50116000.0 [1]
[(R)-3-((R)-6-Amino-purin-9-yl)-cyclopentyloxy]-acetic acidIC50200000.0 [1]
[[(1S,4R)-4-(6-Amino-9H-purine-9-yl)-2-cyclopentene-1-yl]oxy]acetic acidIC5078000.0 [1]
[(S)-3-((S)-6-Amino-purin-9-yl)-cyclopentyloxy]-acetic acidIC5079000.0 [1]
2-[[(1R,4S)-4-(6-Amino-9H-purine-9-yl)-2-cyclopentene-1-yl]oxy]acetohydroximic acidIC5096000.0 [1]
[[(1R,4S)-4-(6-Amino-9H-purine-9-yl)-2-cyclopentene-1-yl]oxy]acetic acidIC5098000.0 [1]
2-[(S)-3-((S)-6-Amino-purin-9-yl)-cyclopentyloxy]-N-hydroxy-acetamideIC50109000.0 [1]
2-[3-(6-Amino-purin-9-yl)-cyclopentyloxy]-N-hydroxy-acetamideIC5010800.0 [1]
(1R,3R)-3-(6-Aminopurin-9-yl)-N-hydroxycyclopentane-1-carboxamideIC5078000.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Adenylate cyclase type V Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/adenylate-cyclase-type-v-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Adenylate cyclase type V Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/adenylate-cyclase-type-v-inhibitors-ic50-ki.
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