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Adenosine deaminase Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
PentostatinKi0.0 [1], 0.03 [2], 0.1 [3]
CoformycinKi0.0 [1], 0.01 [2], 0.1 [3]
(2R,3S)-3-(6-Amino-9H-purin-9-yl)nonan-2-olKi0.4 [1], 3.7 [2], 4.3 [3]
1H-Imidazole-4-carboxamide, 1-(1-(hydroxymethyl)-3-phenylpropyl)-Ki5900.0 [1], 5900000.0 [2]
N''-(4-(5-((1H-Benzimidazol-2-ylamino)methyl)-2-thienyl)-1,3-thiazol-2-YL)guanidineIC50700.0 [1]
N''-(4-(5-((1H-Benzimidazol-2-ylamino)methyl)-2-thienyl)-1,3-thiazol-2-YL)guanidineKi1200.0 [1]
1-[(2R)-1-Hydroxy-4-[6-[3-(1-methylbenzimidazol-2-yl)propanoylamino]indol-1-yl]butan-2-yl]imidazole-4-carboxamideKi7.7 [1]
1-[1-[2-(1-Naphthyl)ethyl]-2-hydroxyethyl]-1H-imidazole-4-carboxamideIC50570.0 [1]
1-[1-[2-(1-Naphthyl)ethyl]-2-hydroxyethyl]-1H-imidazole-4-carboxamideKi680.0 [1]
1H-Imidazole-4-carboxamide, 1-((1R,2S)-2-hydroxy-1-(2-(1-naphthalenyl)ethyl)propyl)-IC5016.0 [1]
1H-Imidazole-4-carboxamide, 1-((1R,2S)-2-hydroxy-1-(2-(1-naphthalenyl)ethyl)propyl)-Ki11.0 [1]
1-[(3R,4S)-1-(2,3-Dichlorophenyl)-4-hydroxypentan-3-yl]-1H-imidazole-4-carboxamideIC5015.0 [1]
1-[(3R,4S)-1-(2,3-Dichlorophenyl)-4-hydroxypentan-3-yl]-1H-imidazole-4-carboxamideKi13.0 [1]
1-[(2R)-4-[5-[3-(4-Chlorophenyl)propoxy]-1-methylindol-3-yl]-1-hydroxybutan-2-yl]imidazole-4-carboxamideIC506.7 [1]
1-[(2R)-4-[5-[3-(4-Chlorophenyl)propoxy]-1-methylindol-3-yl]-1-hydroxybutan-2-yl]imidazole-4-carboxamideKi4.9 [1]
AdenosineKi2180000.0 [1]
Melanotan-1Ki16.0 [1]
NebularineKi7000.0 [1]
1-Deaza-adenosineKi100.0 [1]
(2S,3R)-3-(6-Amino-9H-purin-9-yl)nonan-2-olKi2.0 [1]
9H-Purine-9-ethanol, 6-amino-beta-hexyl-alpha-methyl-, (S-(R*,R*))-Ki80.0 [1]
3-(4-Amino-imidazo[4,5-c]pyridin-1-yl)-nonan-2-olKi6.3 [1]
3-(7-Amino-imidazo[4,5-b]pyridin-3-yl)-nonan-2-olKi120.0 [1]
3-(4-Amino-pyrrolo[2,3-d]pyrimidin-7-yl)-nonan-2-olKi180000.0 [1]
3-(4-Amino-benzoimidazol-1-yl)-nonan-2-olKi15000.0 [1]
(2R)-1-(4-Aminopyrazolo[3,4-d]pyrimidin-2-yl)decan-2-olKi0.05 [1]
1-[(2R)-1-Hydroxy-4-phenylbutan-2-yl]-1H-imidazole-4-carboxamideKi5900.0 [1]
1-{(1R,2S)-2-Hydroxy-1-[2-(2-naphthyloxy)ethyl]propyl}-1H-imidazone-4-carboxamideKi9.8 [1]
(2R,3R,4R,5R)-2-[6-Amino-2-(triazol-1-yl)purin-9-yl]-5-(hydroxymethyl)-3-methyloxolane-3,4-diolIC503700.0 [1]
5-(4-Amino-7-ethyl-5-fluoro-1-isobutyl-1H-benzo[d]imidazol-2-yl)furan-2-ylphosphonic acidIC50100000.0 [1]
8-Aza-NebularineKi40.0 [1]
1-[(3R,4S)-1-[2-(4-Chlorophenyl)-1,3-benzoxazol-4-yl]-4-hydroxypentan-3-yl]imidazole-4-carboxamideIC508.7 [1]
1-[(3R,4S)-1-[2-(4-Chlorophenyl)-1,3-benzoxazol-7-yl]-4-hydroxypentan-3-yl]imidazole-4-carboxamideIC508.6 [1]
1-[(2R)-1-Hydroxy-4-[6-(4-phenylbutoxy)-1H-indol-1-yl]butan-2-yl]-1H-imidazole-4-carboxamideKi12.0 [1]
1-[(R)-1-(Hydroxymethyl)-3-[6-(acetylamino)-1H-indole-1-yl]propyl]-1H-imidazole-4-carboxamideKi1300.0 [1]
1-[(2R)-4-[5-(Hexyloxy)-1H-indol-1-yl]-1-hydroxybutan-2-yl]-1H-imidazole-4-carboxamideKi6200.0 [1]
1-[(2R)-1-Hydroxy-4-[6-[4-(4-methylphenyl)butanoylamino]indol-1-yl]butan-2-yl]imidazole-4-carboxamideKi34.0 [1]
1-[(2R)-1-Hydroxy-4-[6-(6-phenylhexanamido)-1H-indol-1-yl]butan-2-yl]-1H-imidazole-4-carboxamideKi91.0 [1]
1-[(2R)-4-[5-(Hexyloxy)-1-methyl-1H-indol-3-yl]-1-hydroxybutan-2-yl]-1H-imidazole-4-carboxamideKi13.0 [1]
1-[(2R)-1-Hydroxy-4-[6-[3-(4-methoxyphenyl)propanoylamino]indol-1-yl]butan-2-yl]imidazole-4-carboxamideKi57.0 [1]
1-[(2R)-1-Hydroxy-4-[5-(3-phenylpropoxy)-1H-indol-1-yl]butan-2-yl]-1H-imidazole-4-carboxamideKi1900.0 [1]
1-[(2R)-1-Hydroxy-4-[6-(3-phenylpropoxy)-1H-indol-1-yl]butan-2-yl]-1H-imidazole-4-carboxamideKi17.0 [1]
1-[(2R)-4-(6-Butoxy-1H-indol-1-yl)-1-hydroxybutan-2-yl]-1H-imidazole-4-carboxamideKi240.0 [1]
1-[(2R)-4-[6-(Hexyloxy)-1H-indol-1-yl]-1-hydroxybutan-2-yl]-1H-imidazole-4-carboxamideKi55.0 [1]
1-[(2R)-1-Hydroxy-4-[6-[3-(4-methylphenyl)propanoylamino]indol-1-yl]butan-2-yl]imidazole-4-carboxamideKi38.0 [1]
1-[(2R)-1-Hydroxy-4-[6-(3-pyridin-3-ylpropanoylamino)indol-1-yl]butan-2-yl]imidazole-4-carboxamideKi17.0 [1]
1-[(2R)-4-[6-[3-(4-Chlorophenyl)propoxy]indol-1-yl]-1-hydroxybutan-2-yl]imidazole-4-carboxamideKi13.0 [1]
1-[(R)-1-(Hydroxymethyl)-3-[6-(hexanoylamino)-1H-indole-1-yl]propyl]-1H-imidazole-4-carboxamideKi24.0 [1]
9H-Purine-9-ethanol, 6-amino-beta-hexyl-alpha-methyl-, (R,(R*,R*))-Ki122.0 [1]
1-[alpha-(Hydroxymethyl)benzyl]-1H-imidazole-4-carboxamideKi54000.0 [1]
1-[alpha-(Hydroxymethyl)benzyl]-1H-imidazole-4-carboxylic acidKi100000.0 [1]
Methyl 1-(2-hydroxy-1-phenylethyl)-1H-imidazole-4-carboxylateKi100000.0 [1]
1-[alpha-(Hydroxymethyl)benzyl]-1H-imidazole-4-methanolKi100000.0 [1]
[5-(6-Amino-purin-9-yl)-oxazolidin-2-yl]-methanolKi85000.0 [1]
2-[4-[5-[(1H-Indol-2-ylamino)methyl]thiophen-2-yl]-1,3-thiazol-2-yl]guanidineKi1200.0 [1]
1-[(2R)-4-{6-[(Benzylcarbamoyl)amino]-1H-indol-1-yl}-1-hydroxybutan-2-yl]-1H-imidazole-4-carboxamideKi7.5 [1]
1-[(2R)-1-Hydroxy-4-[6-(5-phenylpentanoylamino)indol-1-yl]butan-2-yl]imidazole-4-carboxamideKi11.0 [1]
1-[(2R)-1-Hydroxy-4-[6-(3-phenylpropanamido)-1H-indol-1-yl]butan-2-yl]-1H-imidazole-4-carboxamideKi30.0 [1]
ConformycinKi0.01 [1]
(3R,4S,5R)-2-(4-Aminotriazolo[4,5-d]pyridazin-1-yl)-5-(hydroxymethyl)oxolane-3,4-diolKi1410000.0 [1]
(2R,3R,4S,5R)-2-[(8R)-8-Hydroxy-8H-imidazo[4,5-d][1,3]diazepin-3-yl]-5-(hydroxymethyl)oxolane-3,4-diolKi0.01 [1]
(8R)-3-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-8H-imidazo[4,5-d][1,3]diazepin-8-olKi0.0 [1]
(8R)-3-[(2S,4R,5S)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-7,8-dihydro-6H-imidazo[4,5-b]azepin-8-olKi0.0 [1]
1-[(2R)-1-Hydroxy-4-[1-methyl-5-(3-phenylpropoxy)indol-3-yl]butan-2-yl]imidazole-4-carboxamideKi26.0 [1]
Items per page: 1 - 10 of 64
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References

This online tool may be cited as follows

MLA

"Quest Database™ Adenosine deaminase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Dec. 2024, https://www.aatbio.com/data-sets/adenosine-deaminase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, December 21). Quest Database™ Adenosine deaminase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/adenosine-deaminase-inhibitors-ic50-ki.
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